Gene Symbol | Bcap31 |
Entrez Gene ID | 27061 |
Full Name | B cell receptor associated protein 31 |
Synonyms | Bap31 |
General protein information |
|
Gene Type | protein-coding |
Organism | Mus musculus(house mouse) |
Genome |
ORF » Species Summary » Mus musculus » Bcap31 cDNA ORF clone
gRNAs
Gene Symbol | Bcap31 |
Entrez Gene ID | 27061 |
Full Name | B cell receptor associated protein 31 |
Synonyms | Bap31 |
General protein information |
|
Gene Type | protein-coding |
Organism | Mus musculus(house mouse) |
Genome |
mRNA | Protein | Name |
---|---|---|
XM_006528048.2 | XP_006528111.1 | B-cell receptor-associated protein 31 isoform X1 |
XM_011247600.2 | XP_011245902.1 | B-cell receptor-associated protein 31 isoform X1 |
XM_011247600.3 | XP_011245902.1 | B-cell receptor-associated protein 31 isoform X1 |
NM_001313698.1 | NP_001300627.1 | B-cell receptor-associated protein 31 |
XM_006528048.3 | XP_006528111.1 | B-cell receptor-associated protein 31 isoform X1 |
NM_012060.5 | NP_036190.2 | B-cell receptor-associated protein 31 |
Homo sapiens (human) | BCAP31 | NP_001132929.1 |
Rattus norvegicus (Norway rat) | Bcap31 | NP_001004224.1 |
Anopheles gambiae (African malaria mosquito) | AgaP_AGAP010557 | XP_314530.4 |
Canis lupus familiaris (dog) | BCAP31 | XP_005642052.1 |
Caenorhabditis elegans (roundworm) | Y54G2A.18 | NP_500267.1 |
Danio rerio (zebrafish) | bcap31 | NP_956386.1 |
Xenopus tropicalis (tropical clawed frog) | bcap31 | NP_988982.1 |
Bos taurus (cattle) | BCAP31 | NP_001014941.1 |
Drosophila melanogaster (fruit fly) | CG13887 | NP_728548.1 |
BCAP31 | XP_001085171.1 | |
Mus musculus (house mouse) | Bcap31 | NP_036190.2 |
Hepatocyte-specific deletion of BAP31 promotes SREBP1C activation, promotes hepatic lipid accumulation, and worsens IR in mice.
Xu JL, Li LY, Wang YQ, Li YQ, Shan M, Sun SZ, Yu Y, Wang B
Journal of lipid research59(1)35-47(2018 Jan)
BAP31 is involved in T cell activation through TCR signal pathways.
Niu K, Xu J, Cao Y, Hou Y, Shan M, Wang Y, Xu Y, Sun M, Wang B
Scientific reports744809(2017 Mar)
Epitope Mapping of Antibodies Suggests the Novel Membrane Topology of B-Cell Receptor Associated Protein 31 on the Cell Surface of Embryonic Stem Cells: The Novel Membrane Topology of BAP31.
Kim WT, Choi HS, Hwang HJ, Jung HS, Ryu CJ
PloS one10(6)e0130670(2015)
CDIP1-BAP31 complex transduces apoptotic signals from endoplasmic reticulum to mitochondria under endoplasmic reticulum stress.
Namba T, Tian F, Chu K, Hwang SY, Yoon KW, Byun S, Hiraki M, Mandinova A, Lee SW
Cell reports5(2)331-9(2013 Oct)
GeneRIFs: Gene References Into Functions What's a GeneRIF?
The C-terminal domain of BAP31 is exposed on the cell surface of mouse embryonic stem cells.
Title: Epitope Mapping of Antibodies Suggests the Novel Membrane Topology of B-Cell Receptor Associated Protein 31 on the Cell Surface of Embryonic Stem Cells: The Novel Membrane Topology of BAP31.
BAP31/CDIP1-mediated regulation of mitochondrial apoptosis pathway represents a mechanism for establishing an ER-mitochondrial crosstalk for ER-stress-mediated apoptosis.
Title: CDIP1-BAP31 complex transduces apoptotic signals from endoplasmic reticulum to mitochondria under endoplasmic reticulum stress.
Data suggest that endoplasmic reticulum-localized Bcl2 protects against a Bax/Bak-independent cell death pathway initiated by the p20 fragment of Bap31.
Title: Bcl2 at the endoplasmic reticulum protects against a Bax/Bak-independent paraptosis-like cell death pathway initiated via p20Bap31.
interaction of P450 2C2 with BAP31 is important for its ER retention and expression level and that BAP31 may be involved in the regulation of apoptosis induced by the ER overload response to increased expression of P450.
Title: BAP31 is involved in the retention of cytochrome P450 2C2 in the endoplasmic reticulum.
These results suggest that a compositional change of AMPA receptor (increase of GluR1) and upregulation of the Bap31 gene may be implicated in fatigue in mice.
Title: Increase of AMPA receptor glutamate receptor 1 subunit and B-cell receptor-associated protein 31 gene expression in hippocampus of fatigued mice.
The following Bcap31 gene cDNA ORF clone sequences were retrieved from the NCBI Reference Sequence Database (RefSeq). These sequences represent the protein coding region of the Bcap31 cDNA ORF which is encoded by the open reading frame (ORF) sequence. ORF sequences can be delivered in our standard vector, pcDNA3.1+/C-(K)DYK or the vector of your choice as an expression/transfection-ready ORF clone. Not the clone you want? Click here to find your clone.
CloneID | OMu09399 | |
Clone ID Related Accession (Same CDS sequence) | XM_006528048.2 , XM_011247600.2 , XM_011247600.3 , NM_001313698.1 , XM_006528048.3 , NM_012060.5 | |
Accession Version | NM_001313698.1 Latest version! | Documents for ORF clone product in default vector |
Sequence Information | ORF Nucleotide Sequence (Length: 738bp) Protein sequence SNP |
|
Vector | pcDNA3.1-C-(k)DYK or customized vector | ![]() |
Clone information | Clone Map | ![]() |
Tag on pcDNA3.1+/C-(K)DYK | C terminal DYKDDDDK tags | |
ORF Insert Method | CloneEZ™ Seamless cloning technology | |
Insert Structure | linear | |
Update Date | 2019-12-28 | |
Organism | Mus musculus(house mouse) | |
Product | B-cell receptor-associated protein 31 | |
Comment | Comment: VALIDATED REFSEQ: This record has undergone validation or preliminary review. The reference sequence was derived from CX226458.1, AL805924.5, AK011500.1 and AI838720.1. Transcript Variant: This variant (2) differs in the 5' UTR compared to variant 1. Variants 1 and 2 both encode the same protein. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Gene record to access additional publications. ##Evidence-Data-START## CDS exon combination :: BC002106.1, AK008043.1 [ECO:0000331] RNAseq introns :: single sample supports all introns SAMN01164131 [ECO:0000348] ##Evidence-Data-END## ##RefSeq-Attributes-START## inferred exon combination :: based on alignments, homology ##RefSeq-Attributes-END## COMPLETENESS: complete on the 3' end. |
1 | ATGAGTTTGC AGTGGACTAC AGTTGCCACC TTCCTCTACG CAGAGGTCTT TGCTGTGTTG |
The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.
RefSeq | NP_001300627.1 |
CDS | 200..937 |
Translation |
Target ORF information:
Target ORF information:
|
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1 | ATGAGTTTGC AGTGGACTAC AGTTGCCACC TTCCTCTACG CAGAGGTCTT TGCTGTGTTG |
The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.
CloneID | OMu09399 | |
Clone ID Related Accession (Same CDS sequence) | XM_006528048.2 , XM_011247600.2 , XM_011247600.3 , NM_001313698.1 , XM_006528048.3 , NM_012060.5 | |
Accession Version | NM_012060.5 Latest version! | Documents for ORF clone product in default vector |
Sequence Information | ORF Nucleotide Sequence (Length: 738bp) Protein sequence SNP |
|
Vector | pcDNA3.1-C-(k)DYK or customized vector | ![]() |
Clone information | Clone Map | ![]() |
Tag on pcDNA3.1+/C-(K)DYK | C terminal DYKDDDDK tags | |
ORF Insert Method | CloneEZ™ Seamless cloning technology | |
Insert Structure | linear | |
Update Date | 2019-11-15 | |
Organism | Mus musculus(house mouse) | |
Product | B-cell receptor-associated protein 31 | |
Comment | Comment: VALIDATED REFSEQ: This record has undergone validation or preliminary review. The reference sequence was derived from AL805924.5, CB954946.1, AK011500.1 and AI838720.1. On Sep 11, 2015 this sequence version replaced NM_012060.4. Transcript Variant: This variant (1) represents the predominant transcript. Variants 1 and 2 both encode the same protein. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Gene record to access additional publications. ##Evidence-Data-START## Transcript exon combination :: AK011500.1, AK151641.1 [ECO:0000332] RNAseq introns :: single sample supports all introns SAMN01164131, SAMN01164142 [ECO:0000348] ##Evidence-Data-END## COMPLETENESS: complete on the 3' end. |
1 | ATGAGTTTGC AGTGGACTAC AGTTGCCACC TTCCTCTACG CAGAGGTCTT TGCTGTGTTG |
The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.
RefSeq | NP_036190.2 |
CDS | 132..869 |
Translation |
Target ORF information:
Target ORF information:
|
![]() |
1 | ATGAGTTTGC AGTGGACTAC AGTTGCCACC TTCCTCTACG CAGAGGTCTT TGCTGTGTTG |
The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.
CloneID | OMu09399 | |
Clone ID Related Accession (Same CDS sequence) | XM_006528048.2 , XM_011247600.2 , XM_011247600.3 , NM_001313698.1 , XM_006528048.3 , NM_012060.5 | |
Accession Version | XM_006528048.2 | Documents for ORF clone product in default vector |
Sequence Information | ORF Nucleotide Sequence (Length: 738bp) Protein sequence SNP |
|
Vector | pcDNA3.1-C-(k)DYK or customized vector | ![]() |
Clone information | Clone Map | ![]() |
Tag on pcDNA3.1+/C-(K)DYK | C terminal DYKDDDDK tags | |
ORF Insert Method | CloneEZ™ Seamless cloning technology | |
Insert Structure | linear | |
Update Date | 2016-06-21 | |
Organism | Mus musculus(house mouse) | |
Product | B-cell receptor-associated protein 31 isoform X1 | |
Comment | Comment: MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_000086.7) annotated using gene prediction method: Gnomon, supported by mRNA and EST evidence. Also see: Documentation of NCBI's Annotation Process On Feb 9, 2015 this sequence version replaced XM_006528048.1. ##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Version :: Mus musculus Annotation Release 106 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 7.1 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END## |
1 | ATGAGTTTGC AGTGGACTAC AGTTGCCACC TTCCTCTACG CAGAGGTCTT TGCTGTGTTG |
The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.
RefSeq | XP_006528111.1 |
CDS | 281..1018 |
Translation |
Target ORF information:
Target ORF information:
|
![]() |
1 | ATGAGTTTGC AGTGGACTAC AGTTGCCACC TTCCTCTACG CAGAGGTCTT TGCTGTGTTG |
The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.
CloneID | OMu09399 | |
Clone ID Related Accession (Same CDS sequence) | XM_006528048.2 , XM_011247600.2 , XM_011247600.3 , NM_001313698.1 , XM_006528048.3 , NM_012060.5 | |
Accession Version | XM_011247600.2 | Documents for ORF clone product in default vector |
Sequence Information | ORF Nucleotide Sequence (Length: 738bp) Protein sequence SNP |
|
Vector | pcDNA3.1-C-(k)DYK or customized vector | ![]() |
Clone information | Clone Map | ![]() |
Tag on pcDNA3.1+/C-(K)DYK | C terminal DYKDDDDK tags | |
ORF Insert Method | CloneEZ™ Seamless cloning technology | |
Insert Structure | linear | |
Update Date | 2016-06-21 | |
Organism | Mus musculus(house mouse) | |
Product | B-cell receptor-associated protein 31 isoform X1 | |
Comment | Comment: MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_000086.7) annotated using gene prediction method: Gnomon, supported by mRNA and EST evidence. Also see: Documentation of NCBI's Annotation Process On Jun 22, 2016 this sequence version replaced XM_011247600.1. ##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Version :: Mus musculus Annotation Release 106 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 7.1 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END## |
1 | ATGAGTTTGC AGTGGACTAC AGTTGCCACC TTCCTCTACG CAGAGGTCTT TGCTGTGTTG |
The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.
RefSeq | XP_011245902.1 |
CDS | 216..953 |
Translation |
Target ORF information:
Target ORF information:
|
![]() |
1 | ATGAGTTTGC AGTGGACTAC AGTTGCCACC TTCCTCTACG CAGAGGTCTT TGCTGTGTTG |
The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.
CloneID | OMu09399 | |
Clone ID Related Accession (Same CDS sequence) | XM_006528048.2 , XM_011247600.2 , XM_011247600.3 , NM_001313698.1 , XM_006528048.3 , NM_012060.5 | |
Accession Version | XM_011247600.3 Latest version! | Documents for ORF clone product in default vector |
Sequence Information | ORF Nucleotide Sequence (Length: 738bp) Protein sequence SNP |
|
Vector | pcDNA3.1-C-(k)DYK or customized vector | ![]() |
Clone information | Clone Map | ![]() |
Tag on pcDNA3.1+/C-(K)DYK | C terminal DYKDDDDK tags | |
ORF Insert Method | CloneEZ™ Seamless cloning technology | |
Insert Structure | linear | |
Update Date | 2019-08-07 | |
Organism | Mus musculus(house mouse) | |
Product | B-cell receptor-associated protein 31 isoform X1 | |
Comment | Comment: MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_000086.7) annotated using gene prediction method: Gnomon, supported by mRNA and EST evidence. Also see: Documentation of NCBI's Annotation Process On Aug 8, 2019 this sequence version replaced XM_011247600.2. ##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Name :: Mus musculus Annotation Release 108 Annotation Version :: 108 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 8.2 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END## |
1 | ATGAGTTTGC AGTGGACTAC AGTTGCCACC TTCCTCTACG CAGAGGTCTT TGCTGTGTTG |
The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.
RefSeq | XP_011245902.1 |
CDS | 173..910 |
Translation |
Target ORF information:
Target ORF information:
|
![]() |
1 | ATGAGTTTGC AGTGGACTAC AGTTGCCACC TTCCTCTACG CAGAGGTCTT TGCTGTGTTG |
The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.
CloneID | OMu09399 | |
Clone ID Related Accession (Same CDS sequence) | XM_006528048.2 , XM_011247600.2 , XM_011247600.3 , NM_001313698.1 , XM_006528048.3 , NM_012060.5 | |
Accession Version | XM_006528048.3 Latest version! | Documents for ORF clone product in default vector |
Sequence Information | ORF Nucleotide Sequence (Length: 738bp) Protein sequence SNP |
|
Vector | pcDNA3.1-C-(k)DYK or customized vector | ![]() |
Clone information | Clone Map | ![]() |
Tag on pcDNA3.1+/C-(K)DYK | C terminal DYKDDDDK tags | |
ORF Insert Method | CloneEZ™ Seamless cloning technology | |
Insert Structure | linear | |
Update Date | 2019-08-07 | |
Organism | Mus musculus(house mouse) | |
Product | B-cell receptor-associated protein 31 isoform X1 | |
Comment | Comment: MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_000086.7) annotated using gene prediction method: Gnomon, supported by mRNA and EST evidence. Also see: Documentation of NCBI's Annotation Process On Aug 8, 2019 this sequence version replaced XM_006528048.2. ##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Name :: Mus musculus Annotation Release 108 Annotation Version :: 108 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 8.2 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END## |
1 | ATGAGTTTGC AGTGGACTAC AGTTGCCACC TTCCTCTACG CAGAGGTCTT TGCTGTGTTG |
The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.
RefSeq | XP_006528111.1 |
CDS | 329..1066 |
Translation |
Target ORF information:
Target ORF information:
|
![]() |
1 | ATGAGTTTGC AGTGGACTAC AGTTGCCACC TTCCTCTACG CAGAGGTCTT TGCTGTGTTG |
The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.
Hepatocyte-specific deletion of BAP31 promotes SREBP1C activation, promotes hepatic lipid accumulation, and worsens IR in mice. |
BAP31 is involved in T cell activation through TCR signal pathways. |
Epitope Mapping of Antibodies Suggests the Novel Membrane Topology of B-Cell Receptor Associated Protein 31 on the Cell Surface of Embryonic Stem Cells: The Novel Membrane Topology of BAP31. |
CDIP1-BAP31 complex transduces apoptotic signals from endoplasmic reticulum to mitochondria under endoplasmic reticulum stress. |