Slc46a2 cDNA ORF clone, Mus musculus(house mouse)
| Gene Symbol | Slc46a2 |
| Entrez Gene ID | 30936 |
| Full Name | solute carrier family 46, member 2 |
| Synonyms | 5430429N04Rik,Ly110,TSO-1C12,Tscot |
| General protein information |
|
| Gene Type | protein-coding |
| Organism | Mus musculus(house mouse) |
| Genome |
mRNA and Protein(s)
| mRNA | Protein | Name |
|---|---|---|
| NM_021053.4 | NP_066395.3 | thymic stromal cotransporter protein |
| Rattus norvegicus (Norway rat) | Slc46a2 | NP_001100122.1 |
| Gallus gallus (chicken) | SLC46A2 | XP_429188.3 |
| Pan troglodytes (chimpanzee) | SLC46A2 | XP_528392.2 |
| Canis lupus familiaris (dog) | SLC46A2 | NP_001002997.1 |
| Xenopus tropicalis (tropical clawed frog) | LOC100487507 | XP_002936742.1 |
| SLC46A2 | XP_001113919.1 | |
| Mus musculus (house mouse) | Slc46a2 | NP_066395.3 |
| Danio rerio (zebrafish) | LOC100002406 | XP_001921462.3 |
| Homo sapiens (human) | SLC46A2 | NP_149040.3 |
| Bos taurus (cattle) | SLC46A2 | NP_001019690.1 |
| Xenopus tropicalis (tropical clawed frog) | LOC100487354 | XP_002936741.2 |
| Xenopus tropicalis (tropical clawed frog) | LOC100487203 | XP_002936740.2 |
Related articles in PubMed
Expression Analyses Revealed Thymic Stromal Co-Transporter/Slc46A2 Is in Stem Cell Populations and Is a Putative Tumor Suppressor.
Kim KY, Lee G, Yoon M, Cho EH, Park CS, Kim MG
Molecules and cells38(6)548-61(2015 Jun)
Thymic epithelial requirement for ?? T cell development revealed in the cell ablation transgenic system with TSCOT promoter.
Lee G, Kim KY, Chang CH, Kim MG
Molecules and cells34(5)481-93(2012 Nov)
TSCOT+ thymic epithelial cell-mediated sensitive CD4 tolerance by direct presentation.
Ahn S, Lee G, Yang SJ, Lee D, Lee S, Shin HS, Kim MC, Lee KN, Palmer DC, Theoret MR, Jenkinson EJ, Anderson G, Restifo NP, Kim MG
PLoS biology6(8)e191(2008 Aug)
Characterization of the mouse gene, human promoter and human cDNA of TSCOT reveals strong interspecies homology.
Chen C, Kim MG, Soo Lyu M, Kozak CA, Schwartz RH, Flomerfelt FA
Biochimica et biophysica acta1493(1-2)159-69(2000 Sep)
A putative 12 transmembrane domain cotransporter expressed in thymic cortical epithelial cells.
Kim MG, Flomerfelt FA, Lee KN, Chen C, Schwartz RH
Journal of immunology (Baltimore, Md. : 1950)164(6)3185-92(2000 Mar)
GeneRIFs: Gene References Into Functions What's a GeneRIF?
Expression profiling of thymic stromal cotransporter (TSCOT), Slc46A2/Ly110, that was shown to be expressed in bipotent precursor and cortical thymic epithelial cells.
Title: Expression Analyses Revealed Thymic Stromal Co-Transporter/Slc46A2 Is in Stem Cell Populations and Is a Putative Tumor Suppressor.
Thymic epithelial requirement for gammadelta T cell development revealed in the cell ablation transgenic system with TSCOT promoter
Title: Thymic epithelial requirement for ?? T cell development revealed in the cell ablation transgenic system with TSCOT promoter.
the introduction of a neoantigen into TSCOT-expressing cells can efficiently establish complete tolerance and suggest a possible application for the deletion of antigen-specific T cells by antigen introduction into TSCOT+ cells.
Title: TSCOT+ thymic epithelial cell-mediated sensitive CD4 tolerance by direct presentation.
The following Slc46a2 gene cDNA ORF clone sequences were retrieved from the NCBI Reference Sequence Database (RefSeq). These sequences represent the protein coding region of the Slc46a2 cDNA ORF which is encoded by the open reading frame (ORF) sequence. ORF sequences can be delivered in our standard vector, pcDNA3.1+/C-(K)DYK or the vector of your choice as an expression/transfection-ready ORF clone. Not the clone you want? Click here to find your clone.
| CloneID | OMu12137 | |
| Clone ID Related Accession (Same CDS sequence) | NM_021053.4 | |
| Accession Version | NM_021053.4 Latest version! | Documents for ORF clone product in default vector |
| Sequence Information | ORF Nucleotide Sequence (Length: 1440bp) Protein sequence SNP |
|
| Vector | pcDNA3.1+/C-(K)DYK or customized vector |  User Manual |
| Clone information | Clone Map | MSDS |
| Tag on pcDNA3.1+/C-(K)DYK | C terminal DYKDDDDK tags | |
| ORF Insert Method | CloneEZ™ Seamless cloning technology | |
| Insert Structure | linear | |
| Update Date | 2019-07-05 | |
| Organism | Mus musculus(house mouse) | |
| Product | thymic stromal cotransporter protein | |
| Comment | Comment: VALIDATED REFSEQ: This record has undergone validation or preliminary review. The reference sequence was derived from AK040063.1 and AL831738.4. On Mar 21, 2009 this sequence version replaced NM_021053.3. ##Evidence-Data-START## Transcript exon combination :: AK017363.1, AK040063.1 [ECO:0000332] RNAseq introns :: single sample supports all introns SAMN00849375, SAMN00849376 [ECO:0000348] ##Evidence-Data-END## | |
1 | ATGGGTCCAG GGGGCACCTG TCCGTGGAGC AGCCGGCTCT CTGGCTTCCG GGTGAGGACT |
The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.
| RefSeq | NP_066395.3 |
| CDS | 136..1575 |
| Translation |
Target ORF information:
Target ORF information:
|
 NM_021053.4 |
ORF Insert Sequence:
1 | ATGGGTCCAG GGGGCACCTG TCCGTGGAGC AGCCGGCTCT CTGGCTTCCG GGTGAGGACT |
The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.
 |
Expression Analyses Revealed Thymic Stromal Co-Transporter/Slc46A2 Is in Stem Cell Populations and Is a Putative Tumor Suppressor. |
|
Thymic epithelial requirement for ?? T cell development revealed in the cell ablation transgenic system with TSCOT promoter. |
|
TSCOT+ thymic epithelial cell-mediated sensitive CD4 tolerance by direct presentation. |
|
Characterization of the mouse gene, human promoter and human cDNA of TSCOT reveals strong interspecies homology. |
|
A putative 12 transmembrane domain cotransporter expressed in thymic cortical epithelial cells. |