Gene Symbol | Far2 |
Entrez Gene ID | 330450 |
Full Name | fatty acyl CoA reductase 2 |
Synonyms | A230046P18,AW048109,BC055759,Mlstd1 |
General protein information |
|
Gene Type | protein-coding |
Organism | Mus musculus(house mouse) |
Genome |
ORF » Species Summary » Mus musculus » Far2 cDNA ORF clone
Gene Symbol | Far2 |
Entrez Gene ID | 330450 |
Full Name | fatty acyl CoA reductase 2 |
Synonyms | A230046P18,AW048109,BC055759,Mlstd1 |
General protein information |
|
Gene Type | protein-coding |
Organism | Mus musculus(house mouse) |
Genome |
mRNA | Protein | Name |
---|---|---|
NM_001347516.1 | NP_001334445.1 | fatty acyl-CoA reductase 2 isoform 1 |
XM_006507070.3 | XP_006507133.1 | fatty acyl-CoA reductase 2 isoform X1 |
NM_178797.4 | NP_848912.1 | fatty acyl-CoA reductase 2 isoform 2 |
NM_178797.3 | NP_848912.1 | fatty acyl-CoA reductase 2 isoform 2 |
XM_006507070.4 | XP_006507133.1 | fatty acyl-CoA reductase 2 isoform X1 |
Homo sapiens (human) | FAR2 | NP_001258712.1 |
Drosophila melanogaster (fruit fly) | CG5065 | NP_001163168.1 |
Caenorhabditis elegans (roundworm) | fard-1 | NP_508505.1 |
FAR2 | XP_001105402.1 | |
Rattus norvegicus (Norway rat) | Far2 | XP_006237759.1 |
Gallus gallus (chicken) | FAR2 | XP_004938124.1 |
Anopheles gambiae (African malaria mosquito) | AgaP_AGAP009690 | XP_318748.4 |
Pan troglodytes (chimpanzee) | FAR2 | XP_001141453.1 |
Bos taurus (cattle) | FAR2 | NP_001069490.1 |
Canis lupus familiaris (dog) | FAR2 | XP_534853.1 |
Mus musculus (house mouse) | Far2 | NP_848912.1 |
Arabidopsis thaliana (thale cress) | MS2 | NP_187805.1 |
Oryza sativa (rice) | Os03g0167600 | NP_001049083.1 |
Systematic screening for skin, hair, and nail abnormalities in a large-scale knockout mouse program.
Sundberg JP, Dadras SS, Silva KA, Kennedy VE, Garland G, Murray SA, Sundberg BA, Schofield PN, Pratt CH
PloS one12(7)e0180682(2017)
High-throughput discovery of novel developmental phenotypes.
Dickinson ME, Flenniken AM, Ji X, Teboul L, Wong MD, White JK, Meehan TF, Weninger WJ, Westerberg H, Adissu H, Baker CN, Bower L, Brown JM, Caddle LB, Chiani F, Clary D, Cleak J, Daly MJ, Denegre JM, Doe B, Dolan ME, Edie SM, Fuchs H, Gailus-Durner V, Galli A, Gambadoro A, Gallegos J, Guo S, Horner NR, Hsu CW, Johnson SJ, Kalaga S, Keith LC, Lanoue L, Lawson TN, Lek M, Mark M, Marschall S, Mason J, McElwee ML, Newbigging S, Nutter LM, Peterson KA, Ramirez-Solis R, Rowland DJ, Ryder E, Samocha KE, Seavitt JR, Selloum M, Szoke-Kovacs Z, Tamura M, Trainor AG, Tudose I, Wakana S, Warren J, Wendling O, West DB, Wong L, Yoshiki A, , , , , , , , , MacArthur DG, Tocchini-Valentini GP, Gao X, Flicek P, Bradley A, Skarnes WC, Justice MJ, Parkinson HE, Moore M, Wells S, Braun RE, Svenson KL, de Angelis MH, Herault Y, Mohun T, Mallon AM, Henkelman RM, Brown SD, Adams DJ, Lloyd KC, McKerlie C, Beaudet AL, Bu?an M, Murray SA
Nature537(7621)508-514(2016 09)
GeneRIFs: Gene References Into Functions What's a GeneRIF?
Mouse strains with mesangial matrix expansion contain a 9-bp sequence in the 5' untranslated region of Far2 that is absent in most of the strains without it.
Title: Genetic analysis of mesangial matrix expansion in aging mice and identification of Far2 as a candidate gene.
wax monoester synthesis in mammals involves a two step biosynthetic pathway catalyzed by fatty acyl-CoA reductase and wax synthase enzymes
Title: Mammalian wax biosynthesis. II. Expression cloning of wax synthase cDNAs encoding a member of the acyltransferase enzyme family.
fatty alcohol synthesis in mammals is accomplished by two fatty acyl-CoA reductase isozymes that are expressed at high levels in tissues known to synthesize wax monoesters and ether lipids
Title: Mammalian wax biosynthesis. I. Identification of two fatty acyl-Coenzyme A reductases with different substrate specificities and tissue distributions.
The following Far2 gene cDNA ORF clone sequences were retrieved from the NCBI Reference Sequence Database (RefSeq). These sequences represent the protein coding region of the Far2 cDNA ORF which is encoded by the open reading frame (ORF) sequence. ORF sequences can be delivered in our standard vector, pcDNA3.1+/C-(K)DYK or the vector of your choice as an expression/transfection-ready ORF clone. Not the clone you want? Click here to find your clone.
CloneID | OMu37903 | |
Clone ID Related Accession (Same CDS sequence) | NM_001347516.1 , XM_006507070.3 , XM_006507070.4 | |
Accession Version | NM_001347516.1 Latest version! | Documents for ORF clone product in default vector |
Sequence Information | ORF Nucleotide Sequence (Length: 1548bp) Protein sequence SNP |
|
Vector | pcDNA3.1-C-(k)DYK or customized vector | User Manual |
Clone information | Clone Map | MSDS |
Tag on pcDNA3.1+/C-(K)DYK | C terminal DYKDDDDK tags | |
ORF Insert Method | CloneEZ™ Seamless cloning technology | |
Insert Structure | linear | |
Update Date | 2019-12-31 | |
Organism | Mus musculus(house mouse) | |
Product | fatty acyl-CoA reductase 2 isoform 1 | |
Comment | Comment: VALIDATED REFSEQ: This record has undergone validation or preliminary review. The reference sequence was derived from AK137298.1, BC055759.1 and AW048109.1. On Nov 30, 2016 this sequence version replaced XM_006507069.3. Transcript Variant: This variant (1) encodes the longer isoform (1). ##Evidence-Data-START## Transcript exon combination :: AK137298.1, SRR1660819.195503.1 [ECO:0000332] RNAseq introns :: single sample supports all introns SAMN00849377, SAMN00849378 [ECO:0000348] ##Evidence-Data-END## COMPLETENESS: complete on the 3' end. |
1 | ATGTCCATGA TCGCAGCTTT CTACAGCAAC AAGTCTATCC TCATCACAGG GGCCACAGGC |
The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.
RefSeq | NP_001334445.1 |
CDS | 135..1682 |
Translation |
Target ORF information:
Target ORF information:
|
NM_001347516.1 |
1 | ATGTCCATGA TCGCAGCTTT CTACAGCAAC AAGTCTATCC TCATCACAGG GGCCACAGGC |
The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.
CloneID | OMu37903 | |
Clone ID Related Accession (Same CDS sequence) | NM_001347516.1 , XM_006507070.3 , XM_006507070.4 | |
Accession Version | XM_006507070.3 | Documents for ORF clone product in default vector |
Sequence Information | ORF Nucleotide Sequence (Length: 1548bp) Protein sequence SNP |
|
Vector | pcDNA3.1-C-(k)DYK or customized vector | User Manual |
Clone information | Clone Map | MSDS |
Tag on pcDNA3.1+/C-(K)DYK | C terminal DYKDDDDK tags | |
ORF Insert Method | CloneEZ™ Seamless cloning technology | |
Insert Structure | linear | |
Update Date | 2016-06-21 | |
Organism | Mus musculus(house mouse) | |
Product | fatty acyl-CoA reductase 2 isoform X1 | |
Comment | Comment: MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_000072.6) annotated using gene prediction method: Gnomon, supported by EST evidence. Also see: Documentation of NCBI's Annotation Process On Jun 22, 2016 this sequence version replaced XM_006507070.2. ##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Version :: Mus musculus Annotation Release 106 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 7.1 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END## |
1 | ATGTCCATGA TCGCAGCTTT CTACAGCAAC AAGTCTATCC TCATCACAGG GGCCACAGGC |
The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.
RefSeq | XP_006507133.1 |
CDS | 328..1875 |
Translation |
Target ORF information:
Target ORF information:
|
XM_006507070.3 |
1 | ATGTCCATGA TCGCAGCTTT CTACAGCAAC AAGTCTATCC TCATCACAGG GGCCACAGGC |
The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.
CloneID | OMu07783 | |
Clone ID Related Accession (Same CDS sequence) | NM_178797.4 , NM_178797.3 | |
Accession Version | NM_178797.4 Latest version! | Documents for ORF clone product in default vector |
Sequence Information | ORF Nucleotide Sequence (Length: 1509bp) Protein sequence SNP |
|
Vector | pcDNA3.1-C-(k)DYK or customized vector | User Manual |
Clone information | Clone Map | MSDS |
Tag on pcDNA3.1+/C-(K)DYK | C terminal DYKDDDDK tags | |
ORF Insert Method | CloneEZ™ Seamless cloning technology | |
Insert Structure | linear | |
Update Date | 2020-01-01 | |
Organism | Mus musculus(house mouse) | |
Product | fatty acyl-CoA reductase 2 isoform 2 | |
Comment | Comment: VALIDATED REFSEQ: This record has undergone validation or preliminary review. The reference sequence was derived from AK043388.1 and AK043589.1. On Jan 18, 2018 this sequence version replaced NM_178797.3. Transcript Variant: This variant (2) differs in the 3' coding region and 3' UTR, compared to variant 1. These differences cause a translation frameshift and result in an isoform (2) with a shorter and distinct C-terminus, compared to isoform 1. ##Evidence-Data-START## Transcript exon combination :: AK043589.1, AK038584.1 [ECO:0000332] RNAseq introns :: single sample supports all introns SAMN00849378, SAMN01164131 [ECO:0000348] ##Evidence-Data-END## COMPLETENESS: complete on the 3' end. |
1 | ATGTCCATGA TCGCAGCTTT CTACAGCAAC AAGTCTATCC TCATCACAGG GGCCACAGGC |
The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.
RefSeq | NP_848912.1 |
CDS | 135..1643 |
Translation |
Target ORF information:
Target ORF information:
|
NM_178797.4 |
1 | ATGTCCATGA TCGCAGCTTT CTACAGCAAC AAGTCTATCC TCATCACAGG GGCCACAGGC |
The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.
CloneID | OMu07783 | |
Clone ID Related Accession (Same CDS sequence) | NM_178797.4 , NM_178797.3 | |
Accession Version | NM_178797.3 | Documents for ORF clone product in default vector |
Sequence Information | ORF Nucleotide Sequence (Length: 1509bp) Protein sequence SNP |
|
Vector | pcDNA3.1-C-(k)DYK or customized vector | User Manual |
Clone information | Clone Map | MSDS |
Tag on pcDNA3.1+/C-(K)DYK | C terminal DYKDDDDK tags | |
ORF Insert Method | CloneEZ™ Seamless cloning technology | |
Insert Structure | linear | |
Update Date | 2017-12-09 | |
Organism | Mus musculus(house mouse) | |
Product | fatty acyl-CoA reductase 2 isoform 2 | |
Comment | Comment: PROVISIONAL REFSEQ: This record has not yet been subject to final NCBI review. The reference sequence was derived from AC132613.4. On Nov 17, 2006 this sequence version replaced NM_178797.2. Transcript Variant: This variant (2) differs in the 3' coding region and 3' UTR, compared to variant 1. These differences cause a translation frameshift and result in an isoform (2) with a shorter and distinct C-terminus, compared to isoform 1. Sequence Note: The RefSeq transcript and protein were derived from genomic sequence to make the sequence consistent with the reference genome assembly. The genomic coordinates used for the transcript record were based on transcript alignments. ##Evidence-Data-START## Transcript exon combination :: AK043589.1, AK038584.1 [ECO:0000332] RNAseq introns :: single sample supports all introns SAMN00849378, SAMN01164131 [ECO:0000348] ##Evidence-Data-END## |
1 | ATGTCCATGA TCGCAGCTTT CTACAGCAAC AAGTCTATCC TCATCACAGG GGCCACAGGC |
The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.
RefSeq | NP_848912.1 |
CDS | 135..1643 |
Translation |
Target ORF information:
Target ORF information:
|
NM_178797.3 |
1 | ATGTCCATGA TCGCAGCTTT CTACAGCAAC AAGTCTATCC TCATCACAGG GGCCACAGGC |
The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.
CloneID | OMu37903 | |
Clone ID Related Accession (Same CDS sequence) | NM_001347516.1 , XM_006507070.3 , XM_006507070.4 | |
Accession Version | XM_006507070.4 Latest version! | Documents for ORF clone product in default vector |
Sequence Information | ORF Nucleotide Sequence (Length: 1548bp) Protein sequence SNP |
|
Vector | pcDNA3.1-C-(k)DYK or customized vector | User Manual |
Clone information | Clone Map | MSDS |
Tag on pcDNA3.1+/C-(K)DYK | C terminal DYKDDDDK tags | |
ORF Insert Method | CloneEZ™ Seamless cloning technology | |
Insert Structure | linear | |
Update Date | 2019-08-07 | |
Organism | Mus musculus(house mouse) | |
Product | fatty acyl-CoA reductase 2 isoform X1 | |
Comment | Comment: MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_000072.6) annotated using gene prediction method: Gnomon, supported by EST evidence. Also see: Documentation of NCBI's Annotation Process On Aug 8, 2019 this sequence version replaced XM_006507070.3. ##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Name :: Mus musculus Annotation Release 108 Annotation Version :: 108 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 8.2 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END## |
1 | ATGTCCATGA TCGCAGCTTT CTACAGCAAC AAGTCTATCC TCATCACAGG GGCCACAGGC |
The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.
RefSeq | XP_006507133.1 |
CDS | 315..1862 |
Translation |
Target ORF information:
Target ORF information:
|
XM_006507070.4 |
1 | ATGTCCATGA TCGCAGCTTT CTACAGCAAC AAGTCTATCC TCATCACAGG GGCCACAGGC |
The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.
Systematic screening for skin, hair, and nail abnormalities in a large-scale knockout mouse program. |
High-throughput discovery of novel developmental phenotypes. |