Gene Symbol | Kdm7a |
Entrez Gene ID | 338523 |
Full Name | lysine (K)-specific demethylase 7A |
Synonyms | A630082K20Rik,BB041802,Jhdm1d,mKIAA1718 |
General protein information |
|
Gene Type | protein-coding |
Organism | Mus musculus(house mouse) |
Genome |
ORF » Species Summary » Mus musculus » Kdm7a cDNA ORF clone
Gene Symbol | Kdm7a |
Entrez Gene ID | 338523 |
Full Name | lysine (K)-specific demethylase 7A |
Synonyms | A630082K20Rik,BB041802,Jhdm1d,mKIAA1718 |
General protein information |
|
Gene Type | protein-coding |
Organism | Mus musculus(house mouse) |
Genome |
mRNA | Protein | Name |
---|---|---|
NM_001033430.4 | NP_001028602.2 | lysine-specific demethylase 7A |
JHDM1D | XP_001109325.1 | |
Canis lupus familiaris (dog) | JHDM1D | XP_005629614.1 |
Homo sapiens (human) | KDM7A | NP_085150.1 |
Bos taurus (cattle) | JHDM1D | XP_002687114.2 |
Pan troglodytes (chimpanzee) | JHDM1D | XP_527907.3 |
Mus musculus (house mouse) | Kdm7a | NP_001028602.2 |
Gallus gallus (chicken) | JHDM1D | XP_416344.4 |
Danio rerio (zebrafish) | kdm7ab | NP_001189348.1 |
Xenopus tropicalis (tropical clawed frog) | kdm7a | NP_001072664.1 |
Rattus norvegicus (Norway rat) | Jhdm1d | XP_006236422.1 |
Broad histone H3K4me3 domains in mouse oocytes modulate maternal-to-zygotic transition.
Dahl JA, Jung I, Aanes H, Greggains GD, Manaf A, Lerdrup M, Li G, Kuan S, Li B, Lee AY, Preissl S, Jermstad I, Haugen MH, Suganthan R, Bj?r?s M, Hansen K, Dalen KT, Fedorcsak P, Ren B, Klungland A
Nature537(7621)548-552(2016 09)
Novel skin phenotypes revealed by a genome-wide mouse reverse genetic screen.
Liakath-Ali K, Vancollie VE, Heath E, Smedley DP, Estabel J, Sunter D, Ditommaso T, White JK, Ramirez-Solis R, Smyth I, Steel KP, Watt FM
Nature communications53540(2014 Apr)
Increased expression of histone demethylase JHDM1D under nutrient starvation suppresses tumor growth via down-regulating angiogenesis.
Osawa T, Muramatsu M, Wang F, Tsuchida R, Kodama T, Minami T, Shibuya M
Proceedings of the National Academy of Sciences of the United States of America108(51)20725-9(2011 Dec)
The dual histone demethylase KDM7A promotes neural induction in early chick embryos.
Huang C, Chen J, Zhang T, Zhu Q, Xiang Y, Chen CD, Jing N
Developmental dynamics : an official publication of the American Association of Anatomists239(12)3350-7(2010 Dec)
KIAA1718 is a histone demethylase that erases repressive histone methyl marks.
Yokoyama A, Okuno Y, Chikanishi T, Hashiba W, Sekine H, Fujiki R, Kato S
Genes to cells : devoted to molecular & cellular mechanisms15(8)867-73(2010 Aug)
GeneRIFs: Gene References Into Functions What's a GeneRIF?
increased JHDM1D expression suppresses tumor growth by down-regulating angiogenesis under nutrient starvation
Title: Increased expression of histone demethylase JHDM1D under nutrient starvation suppresses tumor growth via down-regulating angiogenesis.
The KIAA1718, a PHF2/PHF8 subfamily member, possesses histone demethylase activity specific for H3K9 and H3K27, transcriptionally repressive histone marks.
Title: KIAA1718 is a histone demethylase that erases repressive histone methyl marks.
a JmjC domain-containing protein that catalyzes demethylation of both mono- or dimethylated H3K9 and H3K27 [KDM7]
Title: KDM7 is a dual demethylase for histone H3 Lys 9 and Lys 27 and functions in brain development.
The following Kdm7a gene cDNA ORF clone sequences were retrieved from the NCBI Reference Sequence Database (RefSeq). These sequences represent the protein coding region of the Kdm7a cDNA ORF which is encoded by the open reading frame (ORF) sequence. ORF sequences can be delivered in our standard vector, pcDNA3.1+/C-(K)DYK or the vector of your choice as an expression/transfection-ready ORF clone. Not the clone you want? Click here to find your clone.
CloneID | OMu21115 | |
Clone ID Related Accession (Same CDS sequence) | NM_001033430.4 | |
Accession Version | NM_001033430.4 Latest version! | Documents for ORF clone product in default vector |
Sequence Information | ORF Nucleotide Sequence (Length: 2823bp) Protein sequence SNP |
|
Vector | pcDNA3.1-C-(k)DYK or customized vector | User Manual |
Clone information | Clone Map | MSDS |
Tag on pcDNA3.1+/C-(K)DYK | C terminal DYKDDDDK tags | |
ORF Insert Method | CloneEZ™ Seamless cloning technology | |
Insert Structure | linear | |
Update Date | 2019-12-25 | |
Organism | Mus musculus(house mouse) | |
Product | lysine-specific demethylase 7A | |
Comment | Comment: VALIDATED REFSEQ: This record has undergone validation or preliminary review. The reference sequence was derived from AK042834.1, BC145848.1, AK129429.1, AC153818.5 and AW549902.2. On Nov 15, 2007 this sequence version replaced NM_001033430.3. Sequence Note: This RefSeq record was created from transcript and genomic sequence data to make the sequence consistent with the reference genome assembly. The genomic coordinates used for the transcript record were based on transcript alignments. ##Evidence-Data-START## Transcript exon combination :: SRR1660819.134946.1, BC145848.1 [ECO:0000332] RNAseq introns :: mixed/partial sample support SAMN00849374, SAMN00849375 [ECO:0000350] ##Evidence-Data-END## |
1 | ATGGCCGGAG CGGCGGCGGC GGTGGCCGCG GGAGCAGCAG CTGGAGCCGC CGCGGCAGCG |
The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.
RefSeq | NP_001028602.2 |
CDS | 140..2962 |
Translation |
Target ORF information:
Target ORF information:
|
NM_001033430.4 |
1 | ATGGCCGGAG CGGCGGCGGC GGTGGCCGCG GGAGCAGCAG CTGGAGCCGC CGCGGCAGCG |
The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.
Broad histone H3K4me3 domains in mouse oocytes modulate maternal-to-zygotic transition. |
Novel skin phenotypes revealed by a genome-wide mouse reverse genetic screen. |
Increased expression of histone demethylase JHDM1D under nutrient starvation suppresses tumor growth via down-regulating angiogenesis. |
The dual histone demethylase KDM7A promotes neural induction in early chick embryos. |
KIAA1718 is a histone demethylase that erases repressive histone methyl marks. |