Gene Symbol | E2f6 |
Entrez Gene ID | 50496 |
Full Name | E2F transcription factor 6 |
Synonyms | AI462434,E2F6a,E2F6b,EMA |
General protein information |
|
Gene Type | protein-coding |
Organism | Mus musculus(house mouse) |
Genome |
ORF » Species Summary » Mus musculus » E2f6 cDNA ORF clone
Gene Symbol | E2f6 |
Entrez Gene ID | 50496 |
Full Name | E2F transcription factor 6 |
Synonyms | AI462434,E2F6a,E2F6b,EMA |
General protein information |
|
Gene Type | protein-coding |
Organism | Mus musculus(house mouse) |
Genome |
mRNA | Protein | Name |
---|---|---|
XM_006515148.1 | XP_006515211.1 | transcription factor E2F6 isoform X1 |
XM_006515148.2 | XP_006515211.1 | transcription factor E2F6 isoform X1 |
XM_011243882.1 | XP_011242184.1 | transcription factor E2F6 isoform X3 |
XM_006515149.4 | XP_006515212.1 | transcription factor E2F6 isoform X2 |
XM_011243882.2 | XP_011242184.1 | transcription factor E2F6 isoform X3 |
XM_006515147.1 | XP_006515210.1 | transcription factor E2F6 isoform X1 |
XM_006515149.3 | XP_006515212.1 | transcription factor E2F6 isoform X2 |
NM_033270.2 | NP_150373.2 | transcription factor E2F6 |
Homo sapiens (human) | E2F6 | NP_937987.2 |
Danio rerio (zebrafish) | si:ch211-195d17.2 | NP_001025315.1 |
Xenopus tropicalis (tropical clawed frog) | e2f6 | XP_002942229.1 |
Mus musculus (house mouse) | E2f6 | NP_150373.2 |
Gallus gallus (chicken) | E2F6 | NP_001231667.1 |
E2F6 | XP_001088811.1 | |
Pan troglodytes (chimpanzee) | E2F6 | NP_001229273.1 |
Canis lupus familiaris (dog) | E2F6 | XP_852463.1 |
Bos taurus (cattle) | E2F6 | NP_001070316.1 |
Rattus norvegicus (Norway rat) | E2f6 | NP_001094187.1 |
Contrasting effects of an Mdm2 functional polymorphism on tumor phenotypes.
Ortiz GJ, Li Y, Post SM, Pant V, Xiong S, Larsson CA, El-Naggar AK, Johnson DG, Lozano G
Oncogene37(3)332-340(2018 Jan)
E2F6 protein levels modulate drug induced apoptosis in cardiomyocytes.
Major JL, Salih M, Tuana BS
Cellular signalling40230-238(2017 Dec)
SRSF10 Plays a Role in Myoblast Differentiation and Glucose Production via Regulation of Alternative Splicing.
Wei N, Cheng Y, Wang Z, Liu Y, Luo C, Liu L, Chen L, Xie Z, Lu Y, Feng Y
Cell reports13(8)1647-57(2015 Nov)
Interplay between the E2F pathway and ?-adrenergic signaling in the pathological hypertrophic response of myocardium.
Major JL, Salih M, Tuana BS
Journal of molecular and cellular cardiology84179-90(2015 Jul)
A high-resolution spatiotemporal atlas of gene expression of the developing mouse brain.
Thompson CL, Ng L, Menon V, Martinez S, Lee CK, Glattfelder K, Sunkin SM, Henry A, Lau C, Dang C, Garcia-Lopez R, Martinez-Ferre A, Pombero A, Rubenstein JLR, Wakeman WB, Hohmann J, Dee N, Sodt AJ, Young R, Smith K, Nguyen TN, Kidney J, Kuan L, Jeromin A, Kaykas A, Miller J, Page D, Orta G, Bernard A, Riley Z, Smith S, Wohnoutka P, Hawrylycz MJ, Puelles L, Jones AR
Neuron83(2)309-323(2014 Jul)
GeneRIFs: Gene References Into Functions What's a GeneRIF?
These data reveal a novel interplay between the E2F pathway, beta2-adrenergic/PKA/PDE4D, and ERK/c-Src axis in fine tuning the pathological hypertrophic growth response.
Title: Interplay between the E2F pathway and ?-adrenergic signaling in the pathological hypertrophic response of myocardium.
E2f6 was similarly bound to the proximal promoter regions both in embryonic stem cells (ESCs) and epiblast stem cells (EpiSCs)
Title: E2f6-mediated repression of the meiotic Stag3 and Smc1? genes during early embryonic development requires Ezh2 and not the de novo methyltransferase Dnmt3b.
possesses a broad ability to bind to and regulate the meiosis-specific gene population
Title: A conserved E2F6-binding element in murine meiosis-specific gene promoters.
This analysis shows that E2f6 and Bmi1 cooperate in the regulation of Hox genes, and consequently axial skeleton development, but not in the repression of the Ink4a-Arf locus.
Title: E2f6 and Bmi1 cooperate in axial skeletal development.
E2F6 silences SMC1beta and STAG3 in somatic cells
Title: Silencing of the meiotic genes SMC1beta and STAG3 in somatic cells by E2F6.
The following E2f6 gene cDNA ORF clone sequences were retrieved from the NCBI Reference Sequence Database (RefSeq). These sequences represent the protein coding region of the E2f6 cDNA ORF which is encoded by the open reading frame (ORF) sequence. ORF sequences can be delivered in our standard vector, pcDNA3.1+/C-(K)DYK or the vector of your choice as an expression/transfection-ready ORF clone. Not the clone you want? Click here to find your clone.
CloneID | OMu47359 | |
Clone ID Related Accession (Same CDS sequence) | XM_006515148.1 , XM_006515148.2 , XM_006515147.1 | |
Accession Version | XM_006515148.1 | Documents for ORF clone product in default vector |
Sequence Information | ORF Nucleotide Sequence (Length: 714bp) Protein sequence SNP |
|
Vector | pcDNA3.1-C-(k)DYK or customized vector | User Manual |
Clone information | Clone Map | MSDS |
Tag on pcDNA3.1+/C-(K)DYK | C terminal DYKDDDDK tags | |
ORF Insert Method | CloneEZ™ Seamless cloning technology | |
Insert Structure | linear | |
Update Date | 2016-06-21 | |
Organism | Mus musculus(house mouse) | |
Product | transcription factor E2F6 isoform X1 | |
Comment | Comment: MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_000078.6) annotated using gene prediction method: Gnomon, supported by mRNA and EST evidence. Also see: Documentation of NCBI's Annotation Process ##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Version :: Mus musculus Annotation Release 106 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 7.1 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END## |
1 | ATGCCATCAA AAATAAGGAT TAATCTAGAA GAAAATGTAC AGTATGTGTC CATGAGAAAA |
The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.
RefSeq | XP_006515211.1 |
CDS | 278..991 |
Translation |
Target ORF information:
Target ORF information:
|
XM_006515148.1 |
1 | ATGCCATCAA AAATAAGGAT TAATCTAGAA GAAAATGTAC AGTATGTGTC CATGAGAAAA |
The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.
CloneID | OMu47359 | |
Clone ID Related Accession (Same CDS sequence) | XM_006515148.1 , XM_006515148.2 , XM_006515147.1 | |
Accession Version | XM_006515147.1 Latest version! | Documents for ORF clone product in default vector |
Sequence Information | ORF Nucleotide Sequence (Length: 714bp) Protein sequence SNP |
|
Vector | pcDNA3.1-C-(k)DYK or customized vector | User Manual |
Clone information | Clone Map | MSDS |
Tag on pcDNA3.1+/C-(K)DYK | C terminal DYKDDDDK tags | |
ORF Insert Method | CloneEZ™ Seamless cloning technology | |
Insert Structure | linear | |
Update Date | 2019-08-07 | |
Organism | Mus musculus(house mouse) | |
Product | transcription factor E2F6 isoform X1 | |
Comment | Comment: MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_000078.6) annotated using gene prediction method: Gnomon, supported by mRNA and EST evidence. Also see: Documentation of NCBI's Annotation Process ##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Name :: Mus musculus Annotation Release 108 Annotation Version :: 108 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 8.2 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END## |
1 | ATGCCATCAA AAATAAGGAT TAATCTAGAA GAAAATGTAC AGTATGTGTC CATGAGAAAA |
The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.
RefSeq | XP_006515210.1 |
CDS | 534..1247 |
Translation |
Target ORF information:
Target ORF information:
|
XM_006515147.1 |
1 | ATGCCATCAA AAATAAGGAT TAATCTAGAA GAAAATGTAC AGTATGTGTC CATGAGAAAA |
The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.
CloneID | OMu47360 | |
Clone ID Related Accession (Same CDS sequence) | XM_006515149.4 , XM_006515149.3 | |
Accession Version | XM_006515149.3 | Documents for ORF clone product in default vector |
Sequence Information | ORF Nucleotide Sequence (Length: 663bp) Protein sequence SNP |
|
Vector | pcDNA3.1-C-(k)DYK or customized vector | User Manual |
Clone information | Clone Map | MSDS |
Tag on pcDNA3.1+/C-(K)DYK | C terminal DYKDDDDK tags | |
ORF Insert Method | CloneEZ™ Seamless cloning technology | |
Insert Structure | linear | |
Update Date | 2016-06-21 | |
Organism | Mus musculus(house mouse) | |
Product | transcription factor E2F6 isoform X2 | |
Comment | Comment: MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_000078.6) annotated using gene prediction method: Gnomon, supported by mRNA and EST evidence. Also see: Documentation of NCBI's Annotation Process On Jun 22, 2016 this sequence version replaced XM_006515149.2. ##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Version :: Mus musculus Annotation Release 106 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 7.1 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END## |
1 | ATGAGAAAAG CTCTGAAAGT GAAGAGGCCC CGGTTTGATG TGTCACTGGT ATACTTAACT |
The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.
RefSeq | XP_006515212.1 |
CDS | 1605..2267 |
Translation |
Target ORF information:
Target ORF information:
|
XM_006515149.3 |
1 | ATGAGAAAAG CTCTGAAAGT GAAGAGGCCC CGGTTTGATG TGTCACTGGT ATACTTAACT |
The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.
CloneID | OMu16709 | |
Clone ID Related Accession (Same CDS sequence) | NM_033270.2 | |
Accession Version | NM_033270.2 Latest version! | Documents for ORF clone product in default vector |
Sequence Information | ORF Nucleotide Sequence (Length: 819bp) Protein sequence SNP |
|
Vector | pcDNA3.1-C-(k)DYK or customized vector | User Manual |
Clone information | Clone Map | MSDS |
Tag on pcDNA3.1+/C-(K)DYK | C terminal DYKDDDDK tags | |
ORF Insert Method | CloneEZ™ Seamless cloning technology | |
Insert Structure | linear | |
Update Date | 2019-10-18 | |
Organism | Mus musculus(house mouse) | |
Product | transcription factor E2F6 | |
Comment | Comment: VALIDATED REFSEQ: This record has undergone validation or preliminary review. The reference sequence was derived from BY739130.1, BC037656.1 and AI851823.1. On May 16, 2009 this sequence version replaced NM_033270.1. Transcript Variant: This variant (1) represents the protein-coding transcript. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Gene record to access additional publications. ##Evidence-Data-START## Transcript exon combination :: BC057929.1, AF032131.1 [ECO:0000332] RNAseq introns :: single sample supports all introns SAMN00849374, SAMN00849375 [ECO:0000348] ##Evidence-Data-END## COMPLETENESS: complete on the 3' end. |
1 | ATGAGTCAGC AGCGGACGGC GCGGAGACAG CCCAGCCTGC TGGTGGACCC GGCGCAGGAA |
The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.
RefSeq | NP_150373.2 |
CDS | 244..1062 |
Translation |
Target ORF information:
Target ORF information:
|
NM_033270.2 |
1 | ATGAGTCAGC AGCGGACGGC GCGGAGACAG CCCAGCCTGC TGGTGGACCC GGCGCAGGAA |
The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.
CloneID | OMu47359 | |
Clone ID Related Accession (Same CDS sequence) | XM_006515148.1 , XM_006515148.2 , XM_006515147.1 | |
Accession Version | XM_006515148.2 Latest version! | Documents for ORF clone product in default vector |
Sequence Information | ORF Nucleotide Sequence (Length: 714bp) Protein sequence SNP |
|
Vector | pcDNA3.1-C-(k)DYK or customized vector | User Manual |
Clone information | Clone Map | MSDS |
Tag on pcDNA3.1+/C-(K)DYK | C terminal DYKDDDDK tags | |
ORF Insert Method | CloneEZ™ Seamless cloning technology | |
Insert Structure | linear | |
Update Date | 2019-08-07 | |
Organism | Mus musculus(house mouse) | |
Product | transcription factor E2F6 isoform X1 | |
Comment | Comment: MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_000078.6) annotated using gene prediction method: Gnomon, supported by mRNA and EST evidence. Also see: Documentation of NCBI's Annotation Process On Aug 8, 2019 this sequence version replaced XM_006515148.1. ##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Name :: Mus musculus Annotation Release 108 Annotation Version :: 108 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 8.2 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END## |
1 | ATGCCATCAA AAATAAGGAT TAATCTAGAA GAAAATGTAC AGTATGTGTC CATGAGAAAA |
The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.
RefSeq | XP_006515211.1 |
CDS | 574..1287 |
Translation |
Target ORF information:
Target ORF information:
|
XM_006515148.2 |
1 | ATGCCATCAA AAATAAGGAT TAATCTAGAA GAAAATGTAC AGTATGTGTC CATGAGAAAA |
The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.
CloneID | OMu47360 | |
Clone ID Related Accession (Same CDS sequence) | XM_006515149.4 , XM_006515149.3 | |
Accession Version | XM_006515149.4 Latest version! | Documents for ORF clone product in default vector |
Sequence Information | ORF Nucleotide Sequence (Length: 663bp) Protein sequence SNP |
|
Vector | pcDNA3.1-C-(k)DYK or customized vector | User Manual |
Clone information | Clone Map | MSDS |
Tag on pcDNA3.1+/C-(K)DYK | C terminal DYKDDDDK tags | |
ORF Insert Method | CloneEZ™ Seamless cloning technology | |
Insert Structure | linear | |
Update Date | 2019-08-07 | |
Organism | Mus musculus(house mouse) | |
Product | transcription factor E2F6 isoform X2 | |
Comment | Comment: MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_000078.6) annotated using gene prediction method: Gnomon, supported by mRNA and EST evidence. Also see: Documentation of NCBI's Annotation Process On Aug 8, 2019 this sequence version replaced XM_006515149.3. ##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Name :: Mus musculus Annotation Release 108 Annotation Version :: 108 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 8.2 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END## |
1 | ATGAGAAAAG CTCTGAAAGT GAAGAGGCCC CGGTTTGATG TGTCACTGGT ATACTTAACT |
The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.
RefSeq | XP_006515212.1 |
CDS | 1604..2266 |
Translation |
Target ORF information:
Target ORF information:
|
XM_006515149.4 |
1 | ATGAGAAAAG CTCTGAAAGT GAAGAGGCCC CGGTTTGATG TGTCACTGGT ATACTTAACT |
The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.
CloneID | OMu69362 | |
Clone ID Related Accession (Same CDS sequence) | XM_011243882.1 , XM_011243882.2 | |
Accession Version | XM_011243882.2 Latest version! | Documents for ORF clone product in default vector |
Sequence Information | ORF Nucleotide Sequence (Length: 489bp) Protein sequence SNP |
|
Vector | pcDNA3.1-C-(k)DYK or customized vector | User Manual |
Clone information | Clone Map | MSDS |
Tag on pcDNA3.1+/C-(K)DYK | C terminal DYKDDDDK tags | |
ORF Insert Method | CloneEZ™ Seamless cloning technology | |
Insert Structure | linear | |
Update Date | 2019-08-07 | |
Organism | Mus musculus(house mouse) | |
Product | transcription factor E2F6 isoform X3 | |
Comment | Comment: MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_000078.6) annotated using gene prediction method: Gnomon, supported by EST evidence. Also see: Documentation of NCBI's Annotation Process On Aug 8, 2019 this sequence version replaced XM_011243882.1. ##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Name :: Mus musculus Annotation Release 108 Annotation Version :: 108 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 8.2 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END## |
1 | ATGTGCAAAC GCGGGTGCAC TGCGCATGCG GAAAGATGGC CGGCCAGGGA ACCTGAGCGC |
The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.
RefSeq | XP_011242184.1 |
CDS | 32..520 |
Translation |
Target ORF information:
Target ORF information:
|
XM_011243882.2 |
1 | ATGTGCAAAC GCGGGTGCAC TGCGCATGCG GAAAGATGGC CGGCCAGGGA ACCTGAGCGC |
The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.
CloneID | OMu69362 | |
Clone ID Related Accession (Same CDS sequence) | XM_011243882.1 , XM_011243882.2 | |
Accession Version | XM_011243882.1 | Documents for ORF clone product in default vector |
Sequence Information | ORF Nucleotide Sequence (Length: 489bp) Protein sequence SNP |
|
Vector | pcDNA3.1-C-(k)DYK or customized vector | User Manual |
Clone information | Clone Map | MSDS |
Tag on pcDNA3.1+/C-(K)DYK | C terminal DYKDDDDK tags | |
ORF Insert Method | CloneEZ™ Seamless cloning technology | |
Insert Structure | linear | |
Update Date | 2016-06-21 | |
Organism | Mus musculus(house mouse) | |
Product | transcription factor E2F6 isoform X3 | |
Comment | Comment: MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_000078.6) annotated using gene prediction method: Gnomon, supported by EST evidence. Also see: Documentation of NCBI's Annotation Process ##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Version :: Mus musculus Annotation Release 106 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 7.1 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END## |
1 | ATGTGCAAAC GCGGGTGCAC TGCGCATGCG GAAAGATGGC CGGCCAGGGA ACCTGAGCGC |
The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.
RefSeq | XP_011242184.1 |
CDS | 38..526 |
Translation |
Target ORF information:
Target ORF information:
|
XM_011243882.1 |
1 | ATGTGCAAAC GCGGGTGCAC TGCGCATGCG GAAAGATGGC CGGCCAGGGA ACCTGAGCGC |
The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.
Contrasting effects of an Mdm2 functional polymorphism on tumor phenotypes. |
E2F6 protein levels modulate drug induced apoptosis in cardiomyocytes. |
SRSF10 Plays a Role in Myoblast Differentiation and Glucose Production via Regulation of Alternative Splicing. |
Interplay between the E2F pathway and ?-adrenergic signaling in the pathological hypertrophic response of myocardium. |
A high-resolution spatiotemporal atlas of gene expression of the developing mouse brain. |