Ttpa cDNA ORF clone, Mus musculus(house mouse)

Gene
Clones
gRNAs

Gene Symbol	Ttpa
Entrez Gene ID	50500
Full Name	tocopherol (alpha) transfer protein
Synonyms	alpha-TTP
General protein information	Preferred Names tocopherol (alpha) transfer protein Names alpha-tocopherol transfer protein alpha TTP
Gene Type	protein-coding
Organism	Mus musculus(house mouse)
Genome	Chromosome: 4 Map Location: 4 A3\|4 7.76 cM

mRNA and Protein(s)

mRNA	Protein	Name
XM_017320306.1	XP_017175795.1	alpha-tocopherol transfer protein isoform X1
XM_030253651.1	XP_030109511.1	alpha-tocopherol transfer protein isoform X2
NM_015767.4	NP_056582.1	alpha-tocopherol transfer protein isoform 1
NM_001317723.1	NP_001304652.1	alpha-tocopherol transfer protein isoform 2
XM_017320306.2	XP_017175795.1	alpha-tocopherol transfer protein isoform X1

Pathways from BioSystems

Homologies

Pan troglodytes (chimpanzee)	TTPA	XP_528150.2
Rattus norvegicus (Norway rat)	Ttpa	NP_037180.1
Gallus gallus (chicken)	TTPA	XP_001234376.2
Bos taurus (cattle)	TTPA	NP_001193605.1
Danio rerio (zebrafish)	ttpa	NP_956025.2
	TTPA	XP_001092014.1
Mus musculus (house mouse)	Ttpa	NP_056582.1
Homo sapiens (human)	TTPA	NP_000361.1
Canis lupus familiaris (dog)	TTPA	XP_005638207.1

Gene Ontology
Bibliography

Related articles in PubMed

Vitamin transporters in mice brain with aging.
Marcos P, Gonz?lez-Fuentes J, Castro-V?zquez L, Lozano MV, Santander-Ortega MJ, Rodr?guez-Robledo V, Villaseca-Gonz?lez N, Arroyo-Jim?nez MM
Journal of anatomy(2018 Jan)

Enhanced Phospholipase A2 Group 3 Expression by Oxidative Stress Decreases the Insulin-Degrading Enzyme.
Yui D, Nishida Y, Nishina T, Mogushi K, Tajiri M, Ishibashi S, Ajioka I, Ishikawa K, Mizusawa H, Murayama S, Yokota T
PloS one10(12)e0143518(2015)

Vitamin E is essential for Purkinje neuron integrity.
Ulatowski L, Parker R, Warrier G, Sultana R, Butterfield DA, Manor D
Neuroscience260120-9(2014 Feb)

Impaired ?-TTP-PIPs interaction underlies familial vitamin E deficiency.
Kono N, Ohto U, Hiramatsu T, Urabe M, Uchida Y, Satow Y, Arai H
Science (New York, N.Y.)340(6136)1106-10(2013 May)

GeneRIFs: Gene References Into Functions What's a GeneRIF?

alpha-TTP protects against CQ toxicity by preventing CQ accumulation in acidic organelles through a mechanism distinct from vitamin E transport.
Title: A novel role for ?-tocopherol transfer protein (?-TTP) in protecting against chloroquine toxicity.

Results suggest that lipid peroxidation due to depletion of alpha-tocopherol impairs Abeta clearances from the brain and from the blood, possibly causing increased Abeta accumulation in Ttpa(-/-)APPsw brain and plasma.
Title: Depletion of vitamin E increases amyloid beta accumulation by decreasing its clearances from brain and blood in a mouse model of Alzheimer disease.

Increase expression of tPA implicate fibrinolysis in ALD progression.
Title: Direct effects of alcohol on hepatic fibrinolytic balance: implications for alcoholic liver disease.

alpha-tocopherol deficiency decreases oxidative stress and unmasks alpha-tocopherol-dependent regulation of mitochondrial function in the brain
Title: Prolonged alpha-tocopherol deficiency decreases oxidative stress and unmasks alpha-tocopherol-dependent regulation of mitochondrial function in the brain.

The results show that both gender and the hepatic alpha-TTP, but not brain alpha-TTP gene expression are important in determining alpha-T concentrations within the brain.
Title: Mice lacking alpha-tocopherol transfer protein gene have severe alpha-tocopherol deficiency in multiple regions of the central nervous system.

The following Ttpa gene cDNA ORF clone sequences were retrieved from the NCBI Reference Sequence Database (RefSeq). These sequences represent the protein coding region of the Ttpa cDNA ORF which is encoded by the open reading frame (ORF) sequence. ORF sequences can be delivered in our standard vector, pcDNA3.1⁺/C-(K)DYK or the vector of your choice as an expression/transfection-ready ORF clone. Not the clone you want? Click here to find your clone.

***CloneID	Accession No.	Definition	**Vector	*Turnaround time	Price (USD)
OMu21766	NM_015767.4 Latest version!	Mus musculus tocopherol (alpha) transfer protein (Ttpa), transcript variant 1, mRNA.	pcDNA3.1-C-(k)DYK or customized vector	7-9	$188.30 $269.00
OMu69365	NM_001317723.1 Latest version!	Mus musculus tocopherol (alpha) transfer protein (Ttpa), transcript variant 2, mRNA.	pcDNA3.1-C-(k)DYK or customized vector	7-9	$139.30 $199.00
OMu69365	XM_017320306.2 Latest version!	Mus musculus tocopherol (alpha) transfer protein (Ttpa), transcript variant X1, mRNA.	pcDNA3.1-C-(k)DYK or customized vector	9-11	$139.30 $199.00
OMu88576	XM_030253651.1 Latest version!	Mus musculus tocopherol (alpha) transfer protein (Ttpa), transcript variant X2, mRNA.	pcDNA3.1-C-(k)DYK or customized vector	9-11	$69.30 $99.00
View Old Accession Versions >>
OMu69365	XM_017320306.1	Mus musculus tocopherol (alpha) transfer protein (Ttpa), transcript variant X1, mRNA.	pcDNA3.1-C-(k)DYK or customized vector	7-9	$139.30 $199.00
Hide Old Accession Versions >>

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** GenScript guarantees 100% sequence accuracy of all synthetic DNA constructs we deliver, but we do not guarantee protein expression in your experimental system. Protein expression is influenced by many factors that may vary between experiments or laboratories. In addition, please pay attention to the signal peptide, propeptide and transit peptide in target ORF, which may affect the choice of vector (N/C terminal tag vector).

***One clone ID might be correlated to multiple accession numbers, which share the same CDS sequence.

Reference Sequences (Refseq)

Ttpa ( NM_015767.4 ) cDNA ORF clone, Mus musculus(house mouse) -> NP_056582.1 Mus musculus tocopherol (alpha) transfer protein (Ttpa), transcript variant 1, mRNA.

Price & Availability↑

CloneID	OMu21766
Clone ID Related Accession (Same CDS sequence)	NM_015767.4
Accession Version	NM_015767.4 Latest version!	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 837bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2019-07-30
Organism	Mus musculus(house mouse)
Product	alpha-tocopherol transfer protein isoform 1
Comment	Comment: VALIDATED REFSEQ: This record has undergone validation or preliminary review. The reference sequence was derived from BY072913.1, AL732527.6, AK050374.1, AK004882.1 and AV026942.2. On Dec 4, 2015 this sequence version replaced NM_015767.3. Transcript Variant: This variant (1) represents the longer transcript and encodes the longer isoform (1). Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Gene record to access additional publications. ##Evidence-Data-START## Transcript exon combination :: SRR1660815.108174.1, AK050374.1 [ECO:0000332] RNAseq introns :: single sample supports all introns SAMN00849374, SAMN00849375 [ECO:0000348] ##Evidence-Data-END## COMPLETENESS: complete on the 3' end.

ATGGCAGAGA TGCGGCCGGG GCCATTGGTT GGGAAACAGC TCAACGAGCT GCCCGACCAC 
TCGCCGCTGC TCCAGCCCGG CCTGGCGGAG CTCAGGCGCC GGGTGCAGGA GGCAGGCGTC 
CCGCAGACCC CGCAGCCTCT CACAGACGCT TTCCTGCTGC GCTTCCTGCG CGCCCGGGAT 
TTCGATCTGG ATCTGGCCTG GCGCTTAATG AAAAACTATT ATAAATGGCG AGCAGAATGC 
CCAGAATTAA GTGCAGATCT ACGCCCTAGA AGTATCCTTG GACTTCTGAA AGCTGGCTAC 
CATGGCGTGC TCAGGTCCCG GGATTCTACT GGCAGTAGAG TTCTCATTTA CAGAATTGCA 
TACTGGGACC CAAAAGTTTT TACAGCTTAT GATGTATTTC GTGTAAGTCT GATCACATCA 
GAGCTCATTG TACAGGAGGT GGAAACTCAA CGCAATGGAG TTAAAGCTAT ATTTGACCTG 
GAAGGCTGGC AGGTTTCTCA TGCTTTCCAA ATTACCCCAT CTGTAGCCAA GAAGATTGCT 
GCTGTACTTA CAGATTCCTT TCCACTGAAA GTTCGTGGGA TCCATTTGAT AAATGAGCCA 
GTCATTTTCC ATGCTGTCTT CTCCATGATT AAACCATTTC TGACTGAAAA GATTAAGGAC 
CGGATTCATC TGCACGGGAA CAACTACAAA TCAAGCATGC TTCAGCACTT CCCAGACATT 
CTTCCTCGGG AATATGGCGG TAAAGAGTTC TCCATGGAGG ATATTTGTCA GGAGTGGACA 
AATTTTATAA TGAAGTCTGA AGATTATCTC AGCAGCATTT CTGAGACCAT CCAATGA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	NP_056582.1
CDS	112..948
Translation	MAEMRPGPLVGKQLNELPDHSPLLQPGLAELRRRVQEAGVPQTPQPLTDAFLLRFLRARDFDLDLAWRLMKNYYKWRAECPELSADLRPRSILGLLKAGYHGVLRSRDSTGSRVLIYRIAYWDPKVFTAYDVFRVSLITSELIVQEVETQRNGVKAIFDLEGWQVSHAFQITPSVAKKIAAVLTDSFPLKVRGIHLINEPVIFHAVFSMIKPFLTEKIKDRIHLHGNNYKSSMLQHFPDILPREYGGKEFSMEDICQEWTNFIMKSEDYLSSISETIQ

Target ORF information:

RefSeq Version	NM_015767.4
Organism	Mus musculus(house mouse)
Definition	Mus musculus tocopherol (alpha) transfer protein (Ttpa), transcript variant 1, mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

NM_015767.4

ORF Insert Sequence:

ATGGCAGAGA TGCGGCCGGG GCCATTGGTT GGGAAACAGC TCAACGAGCT GCCCGACCAC 
TCGCCGCTGC TCCAGCCCGG CCTGGCGGAG CTCAGGCGCC GGGTGCAGGA GGCAGGCGTC 
CCGCAGACCC CGCAGCCTCT CACAGACGCT TTCCTGCTGC GCTTCCTGCG CGCCCGGGAT 
TTCGATCTGG ATCTGGCCTG GCGCTTAATG AAAAACTATT ATAAATGGCG AGCAGAATGC 
CCAGAATTAA GTGCAGATCT ACGCCCTAGA AGTATCCTTG GACTTCTGAA AGCTGGCTAC 
CATGGCGTGC TCAGGTCCCG GGATTCTACT GGCAGTAGAG TTCTCATTTA CAGAATTGCA 
TACTGGGACC CAAAAGTTTT TACAGCTTAT GATGTATTTC GTGTAAGTCT GATCACATCA 
GAGCTCATTG TACAGGAGGT GGAAACTCAA CGCAATGGAG TTAAAGCTAT ATTTGACCTG 
GAAGGCTGGC AGGTTTCTCA TGCTTTCCAA ATTACCCCAT CTGTAGCCAA GAAGATTGCT 
GCTGTACTTA CAGATTCCTT TCCACTGAAA GTTCGTGGGA TCCATTTGAT AAATGAGCCA 
GTCATTTTCC ATGCTGTCTT CTCCATGATT AAACCATTTC TGACTGAAAA GATTAAGGAC 
CGGATTCATC TGCACGGGAA CAACTACAAA TCAAGCATGC TTCAGCACTT CCCAGACATT 
CTTCCTCGGG AATATGGCGG TAAAGAGTTC TCCATGGAGG ATATTTGTCA GGAGTGGACA 
AATTTTATAA TGAAGTCTGA AGATTATCTC AGCAGCATTT CTGAGACCAT CCAATGA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

Ttpa ( NM_001317723.1 ) cDNA ORF clone, Mus musculus(house mouse) -> NP_001304652.1 Mus musculus tocopherol (alpha) transfer protein (Ttpa), transcript variant 2, mRNA.

Price & Availability↑

CloneID	OMu69365
Clone ID Related Accession (Same CDS sequence)	XM_017320306.1 , NM_001317723.1 , XM_017320306.2
Accession Version	NM_001317723.1 Latest version!	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 630bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2019-07-30
Organism	Mus musculus(house mouse)
Product	alpha-tocopherol transfer protein isoform 2
Comment	Comment: VALIDATED REFSEQ: This record has undergone validation or preliminary review. The reference sequence was derived from AL732527.6. On Dec 4, 2015 this sequence version replaced XM_011250064.1. Transcript Variant: This variant (2) uses an alternate 5' terminal exon, resulting in a novel 5' UTR, and the use of a downstream start codon, compared to variant 1. The encoded isoform (2) has a shorter N-terminus compared isoform 1. Sequence Note: The RefSeq transcript and protein were derived from genomic sequence to make the sequence consistent with the reference genome assembly. The genomic coordinates used for the transcript record were based on alignments. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Gene record to access additional publications. ##Evidence-Data-START## Transcript exon combination :: BC026882.1, BI110384.1 [ECO:0000332] RNAseq introns :: single sample supports all introns SAMN00849374, SAMN00849375 [ECO:0000348] ##Evidence-Data-END## COMPLETENESS: complete on the 3' end.

ATGAAAAACT ATTATAAATG GCGAGCAGAA TGCCCAGAAT TAAGTGCAGA TCTACGCCCT 
AGAAGTATCC TTGGACTTCT GAAAGCTGGC TACCATGGCG TGCTCAGGTC CCGGGATTCT 
ACTGGCAGTA GAGTTCTCAT TTACAGAATT GCATACTGGG ACCCAAAAGT TTTTACAGCT 
TATGATGTAT TTCGTGTAAG TCTGATCACA TCAGAGCTCA TTGTACAGGA GGTGGAAACT 
CAACGCAATG GAGTTAAAGC TATATTTGAC CTGGAAGGCT GGCAGGTTTC TCATGCTTTC 
CAAATTACCC CATCTGTAGC CAAGAAGATT GCTGCTGTAC TTACAGATTC CTTTCCACTG 
AAAGTTCGTG GGATCCATTT GATAAATGAG CCAGTCATTT TCCATGCTGT CTTCTCCATG 
ATTAAACCAT TTCTGACTGA AAAGATTAAG GACCGGATTC ATCTGCACGG GAACAACTAC 
AAATCAAGCA TGCTTCAGCA CTTCCCAGAC ATTCTTCCTC GGGAATATGG CGGTAAAGAG 
TTCTCCATGG AGGATATTTG TCAGGAGTGG ACAAATTTTA TAATGAAGTC TGAAGATTAT 
CTCAGCAGCA TTTCTGAGAC CATCCAATGA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	NP_001304652.1
CDS	108..737
Translation	MKNYYKWRAECPELSADLRPRSILGLLKAGYHGVLRSRDSTGSRVLIYRIAYWDPKVFTAYDVFRVSLITSELIVQEVETQRNGVKAIFDLEGWQVSHAFQITPSVAKKIAAVLTDSFPLKVRGIHLINEPVIFHAVFSMIKPFLTEKIKDRIHLHGNNYKSSMLQHFPDILPREYGGKEFSMEDICQEWTNFIMKSEDYLSSISETIQ

Target ORF information:

RefSeq Version	NM_001317723.1
Organism	Mus musculus(house mouse)
Definition	Mus musculus tocopherol (alpha) transfer protein (Ttpa), transcript variant 2, mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

NM_001317723.1

ORF Insert Sequence:

ATGAAAAACT ATTATAAATG GCGAGCAGAA TGCCCAGAAT TAAGTGCAGA TCTACGCCCT 
AGAAGTATCC TTGGACTTCT GAAAGCTGGC TACCATGGCG TGCTCAGGTC CCGGGATTCT 
ACTGGCAGTA GAGTTCTCAT TTACAGAATT GCATACTGGG ACCCAAAAGT TTTTACAGCT 
TATGATGTAT TTCGTGTAAG TCTGATCACA TCAGAGCTCA TTGTACAGGA GGTGGAAACT 
CAACGCAATG GAGTTAAAGC TATATTTGAC CTGGAAGGCT GGCAGGTTTC TCATGCTTTC 
CAAATTACCC CATCTGTAGC CAAGAAGATT GCTGCTGTAC TTACAGATTC CTTTCCACTG 
AAAGTTCGTG GGATCCATTT GATAAATGAG CCAGTCATTT TCCATGCTGT CTTCTCCATG 
ATTAAACCAT TTCTGACTGA AAAGATTAAG GACCGGATTC ATCTGCACGG GAACAACTAC 
AAATCAAGCA TGCTTCAGCA CTTCCCAGAC ATTCTTCCTC GGGAATATGG CGGTAAAGAG 
TTCTCCATGG AGGATATTTG TCAGGAGTGG ACAAATTTTA TAATGAAGTC TGAAGATTAT 
CTCAGCAGCA TTTCTGAGAC CATCCAATGA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

Ttpa ( XM_017320306.1 ) cDNA ORF clone, Mus musculus(house mouse) -> XP_017175795.1 Mus musculus tocopherol (alpha) transfer protein (Ttpa), transcript variant X1, mRNA.

Price & Availability↑

CloneID	OMu69365
Clone ID Related Accession (Same CDS sequence)	XM_017320306.1 , NM_001317723.1 , XM_017320306.2
Accession Version	XM_017320306.1	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 630bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2016-06-21
Organism	Mus musculus(house mouse)
Product	alpha-tocopherol transfer protein isoform X1
Comment	Comment: MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_000070.6) annotated using gene prediction method: Gnomon, supported by mRNA and EST evidence. Also see: Documentation of NCBI's Annotation Process ##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Version :: Mus musculus Annotation Release 106 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 7.1 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END##

ATGAAAAACT ATTATAAATG GCGAGCAGAA TGCCCAGAAT TAAGTGCAGA TCTACGCCCT 
AGAAGTATCC TTGGACTTCT GAAAGCTGGC TACCATGGCG TGCTCAGGTC CCGGGATTCT 
ACTGGCAGTA GAGTTCTCAT TTACAGAATT GCATACTGGG ACCCAAAAGT TTTTACAGCT 
TATGATGTAT TTCGTGTAAG TCTGATCACA TCAGAGCTCA TTGTACAGGA GGTGGAAACT 
CAACGCAATG GAGTTAAAGC TATATTTGAC CTGGAAGGCT GGCAGGTTTC TCATGCTTTC 
CAAATTACCC CATCTGTAGC CAAGAAGATT GCTGCTGTAC TTACAGATTC CTTTCCACTG 
AAAGTTCGTG GGATCCATTT GATAAATGAG CCAGTCATTT TCCATGCTGT CTTCTCCATG 
ATTAAACCAT TTCTGACTGA AAAGATTAAG GACCGGATTC ATCTGCACGG GAACAACTAC 
AAATCAAGCA TGCTTCAGCA CTTCCCAGAC ATTCTTCCTC GGGAATATGG CGGTAAAGAG 
TTCTCCATGG AGGATATTTG TCAGGAGTGG ACAAATTTTA TAATGAAGTC TGAAGATTAT 
CTCAGCAGCA TTTCTGAGAC CATCCAATGA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	XP_017175795.1
CDS	194..823
Translation	MKNYYKWRAECPELSADLRPRSILGLLKAGYHGVLRSRDSTGSRVLIYRIAYWDPKVFTAYDVFRVSLITSELIVQEVETQRNGVKAIFDLEGWQVSHAFQITPSVAKKIAAVLTDSFPLKVRGIHLINEPVIFHAVFSMIKPFLTEKIKDRIHLHGNNYKSSMLQHFPDILPREYGGKEFSMEDICQEWTNFIMKSEDYLSSISETIQ

Target ORF information:

RefSeq Version	XM_017320306.1
Organism	Mus musculus(house mouse)
Definition	Mus musculus tocopherol (alpha) transfer protein (Ttpa), transcript variant X1, mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

XM_017320306.1

ORF Insert Sequence:

ATGAAAAACT ATTATAAATG GCGAGCAGAA TGCCCAGAAT TAAGTGCAGA TCTACGCCCT 
AGAAGTATCC TTGGACTTCT GAAAGCTGGC TACCATGGCG TGCTCAGGTC CCGGGATTCT 
ACTGGCAGTA GAGTTCTCAT TTACAGAATT GCATACTGGG ACCCAAAAGT TTTTACAGCT 
TATGATGTAT TTCGTGTAAG TCTGATCACA TCAGAGCTCA TTGTACAGGA GGTGGAAACT 
CAACGCAATG GAGTTAAAGC TATATTTGAC CTGGAAGGCT GGCAGGTTTC TCATGCTTTC 
CAAATTACCC CATCTGTAGC CAAGAAGATT GCTGCTGTAC TTACAGATTC CTTTCCACTG 
AAAGTTCGTG GGATCCATTT GATAAATGAG CCAGTCATTT TCCATGCTGT CTTCTCCATG 
ATTAAACCAT TTCTGACTGA AAAGATTAAG GACCGGATTC ATCTGCACGG GAACAACTAC 
AAATCAAGCA TGCTTCAGCA CTTCCCAGAC ATTCTTCCTC GGGAATATGG CGGTAAAGAG 
TTCTCCATGG AGGATATTTG TCAGGAGTGG ACAAATTTTA TAATGAAGTC TGAAGATTAT 
CTCAGCAGCA TTTCTGAGAC CATCCAATGA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

Ttpa ( XM_017320306.2 ) cDNA ORF clone, Mus musculus(house mouse) -> XP_017175795.1 Mus musculus tocopherol (alpha) transfer protein (Ttpa), transcript variant X1, mRNA.

Price & Availability↑

CloneID	OMu69365
Clone ID Related Accession (Same CDS sequence)	XM_017320306.1 , NM_001317723.1 , XM_017320306.2
Accession Version	XM_017320306.2 Latest version!	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 630bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2019-08-07
Organism	Mus musculus(house mouse)
Product	alpha-tocopherol transfer protein isoform X1
Comment	Comment: MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_000070.6) annotated using gene prediction method: Gnomon, supported by mRNA and EST evidence. Also see: Documentation of NCBI's Annotation Process On Aug 8, 2019 this sequence version replaced XM_017320306.1. ##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Name :: Mus musculus Annotation Release 108 Annotation Version :: 108 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 8.2 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END##

ATGAAAAACT ATTATAAATG GCGAGCAGAA TGCCCAGAAT TAAGTGCAGA TCTACGCCCT 
AGAAGTATCC TTGGACTTCT GAAAGCTGGC TACCATGGCG TGCTCAGGTC CCGGGATTCT 
ACTGGCAGTA GAGTTCTCAT TTACAGAATT GCATACTGGG ACCCAAAAGT TTTTACAGCT 
TATGATGTAT TTCGTGTAAG TCTGATCACA TCAGAGCTCA TTGTACAGGA GGTGGAAACT 
CAACGCAATG GAGTTAAAGC TATATTTGAC CTGGAAGGCT GGCAGGTTTC TCATGCTTTC 
CAAATTACCC CATCTGTAGC CAAGAAGATT GCTGCTGTAC TTACAGATTC CTTTCCACTG 
AAAGTTCGTG GGATCCATTT GATAAATGAG CCAGTCATTT TCCATGCTGT CTTCTCCATG 
ATTAAACCAT TTCTGACTGA AAAGATTAAG GACCGGATTC ATCTGCACGG GAACAACTAC 
AAATCAAGCA TGCTTCAGCA CTTCCCAGAC ATTCTTCCTC GGGAATATGG CGGTAAAGAG 
TTCTCCATGG AGGATATTTG TCAGGAGTGG ACAAATTTTA TAATGAAGTC TGAAGATTAT 
CTCAGCAGCA TTTCTGAGAC CATCCAATGA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	XP_017175795.1
CDS	209..838
Translation	MKNYYKWRAECPELSADLRPRSILGLLKAGYHGVLRSRDSTGSRVLIYRIAYWDPKVFTAYDVFRVSLITSELIVQEVETQRNGVKAIFDLEGWQVSHAFQITPSVAKKIAAVLTDSFPLKVRGIHLINEPVIFHAVFSMIKPFLTEKIKDRIHLHGNNYKSSMLQHFPDILPREYGGKEFSMEDICQEWTNFIMKSEDYLSSISETIQ

Target ORF information:

RefSeq Version	XM_017320306.2
Organism	Mus musculus(house mouse)
Definition	Mus musculus tocopherol (alpha) transfer protein (Ttpa), transcript variant X1, mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

XM_017320306.2

ORF Insert Sequence:

ATGAAAAACT ATTATAAATG GCGAGCAGAA TGCCCAGAAT TAAGTGCAGA TCTACGCCCT 
AGAAGTATCC TTGGACTTCT GAAAGCTGGC TACCATGGCG TGCTCAGGTC CCGGGATTCT 
ACTGGCAGTA GAGTTCTCAT TTACAGAATT GCATACTGGG ACCCAAAAGT TTTTACAGCT 
TATGATGTAT TTCGTGTAAG TCTGATCACA TCAGAGCTCA TTGTACAGGA GGTGGAAACT 
CAACGCAATG GAGTTAAAGC TATATTTGAC CTGGAAGGCT GGCAGGTTTC TCATGCTTTC 
CAAATTACCC CATCTGTAGC CAAGAAGATT GCTGCTGTAC TTACAGATTC CTTTCCACTG 
AAAGTTCGTG GGATCCATTT GATAAATGAG CCAGTCATTT TCCATGCTGT CTTCTCCATG 
ATTAAACCAT TTCTGACTGA AAAGATTAAG GACCGGATTC ATCTGCACGG GAACAACTAC 
AAATCAAGCA TGCTTCAGCA CTTCCCAGAC ATTCTTCCTC GGGAATATGG CGGTAAAGAG 
TTCTCCATGG AGGATATTTG TCAGGAGTGG ACAAATTTTA TAATGAAGTC TGAAGATTAT 
CTCAGCAGCA TTTCTGAGAC CATCCAATGA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

Ttpa ( XM_030253651.1 ) cDNA ORF clone, Mus musculus(house mouse) -> XP_030109511.1 Mus musculus tocopherol (alpha) transfer protein (Ttpa), transcript variant X2, mRNA.

Price & Availability↑

CloneID	OMu88576
Clone ID Related Accession (Same CDS sequence)	XM_030253651.1
Accession Version	XM_030253651.1 Latest version!	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 399bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2019-08-07
Organism	Mus musculus(house mouse)
Product	alpha-tocopherol transfer protein isoform X2
Comment	Comment: MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_000070.6) annotated using gene prediction method: Gnomon, supported by EST evidence. Also see: Documentation of NCBI's Annotation Process ##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Name :: Mus musculus Annotation Release 108 Annotation Version :: 108 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 8.2 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END##

ATGGCAGAGA TGCGGCCGGG GCCATTGGTT GGGAAACAGC TCAACGAGCT GCCCGACCAC 
TCGCCGCTGC TCCAGCCCGG CCTGGCGGAG CTCAGGCGCC GGGTGCAGGA GGCAGGCGTC 
CCGCAGACCC CGCAGCCTCT CACAGACGCT TTCCTGCTGC GCTTCCTGCG CGCCCGGGAT 
TTCGATCTGG ATCTGGCCTG GCGCTTAATG AAAAACTATT ATAAATGGCG AGCAGAATGC 
CCAGAATTAA GTGCAGATCT ACGCCCTAGA AGTATCCTTG GACTTCTGAA AGCTGGCTAC 
CATGGCGTGC TCAGGTCCCG GGATTCTACT GGCAGTAGAG TTCTCATTTA CAGAATTGGA 
GTTCATAGAG GACAGGCTGG CTTTGAACTC ACCGAATAG

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	XP_030109511.1
CDS	106..504
Translation	MAEMRPGPLVGKQLNELPDHSPLLQPGLAELRRRVQEAGVPQTPQPLTDAFLLRFLRARDFDLDLAWRLMKNYYKWRAECPELSADLRPRSILGLLKAGYHGVLRSRDSTGSRVLIYRIGVHRGQAGFELTE

Target ORF information:

RefSeq Version	XM_030253651.1
Organism	Mus musculus(house mouse)
Definition	Mus musculus tocopherol (alpha) transfer protein (Ttpa), transcript variant X2, mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

XM_030253651.1

ORF Insert Sequence:

ATGGCAGAGA TGCGGCCGGG GCCATTGGTT GGGAAACAGC TCAACGAGCT GCCCGACCAC 
TCGCCGCTGC TCCAGCCCGG CCTGGCGGAG CTCAGGCGCC GGGTGCAGGA GGCAGGCGTC 
CCGCAGACCC CGCAGCCTCT CACAGACGCT TTCCTGCTGC GCTTCCTGCG CGCCCGGGAT 
TTCGATCTGG ATCTGGCCTG GCGCTTAATG AAAAACTATT ATAAATGGCG AGCAGAATGC 
CCAGAATTAA GTGCAGATCT ACGCCCTAGA AGTATCCTTG GACTTCTGAA AGCTGGCTAC 
CATGGCGTGC TCAGGTCCCG GGATTCTACT GGCAGTAGAG TTCTCATTTA CAGAATTGGA 
GTTCATAGAG GACAGGCTGG CTTTGAACTC ACCGAATAG

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

PubMed

Vitamin transporters in mice brain with aging.
Journal of anatomy(2018 Jan)
Marcos P,Gonz?lez-Fuentes J,Castro-V?zquez L,Lozano MV,Santander-Ortega MJ,Rodr?guez-Robledo V,Villaseca-Gonz?lez N,Arroyo-Jim?nez MM

Enhanced Phospholipase A2 Group 3 Expression by Oxidative Stress Decreases the Insulin-Degrading Enzyme.
PloS one10(12)e0143518(2015)
Yui D,Nishida Y,Nishina T,Mogushi K,Tajiri M,Ishibashi S,Ajioka I,Ishikawa K,Mizusawa H,Murayama S,Yokota T

Vitamin E is essential for Purkinje neuron integrity.
Neuroscience260120-9(2014 Feb)
Ulatowski L,Parker R,Warrier G,Sultana R,Butterfield DA,Manor D

Impaired ?-TTP-PIPs interaction underlies familial vitamin E deficiency.
Science (New York, N.Y.)340(6136)1106-10(2013 May)
Kono N,Ohto U,Hiramatsu T,Urabe M,Uchida Y,Satow Y,Arai H

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Ttpa cDNA ORF clone, Mus musculus(house mouse)

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Target ORF information:

Target ORF information:

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Target ORF information:

ORF Insert Sequence:

Target ORF information:

Target ORF information:

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Target ORF information:

ORF Insert Sequence:

Target ORF information:

Target ORF information:

ORF Insert Sequence:

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