Gene Symbol | Tyk2 |
Entrez Gene ID | 54721 |
Full Name | tyrosine kinase 2 |
Synonyms | JTK1 |
General protein information |
|
Gene Type | protein-coding |
Organism | Mus musculus(house mouse) |
Genome |
ORF » Species Summary » Mus musculus » Tyk2 cDNA ORF clone
Gene Symbol | Tyk2 |
Entrez Gene ID | 54721 |
Full Name | tyrosine kinase 2 |
Synonyms | JTK1 |
General protein information |
|
Gene Type | protein-coding |
Organism | Mus musculus(house mouse) |
Genome |
mRNA | Protein | Name |
---|---|---|
XM_011242579.2 | XP_011240881.1 | non-receptor tyrosine-protein kinase TYK2 isoform X1 |
XM_030244455.1 | XP_030100315.1 | non-receptor tyrosine-protein kinase TYK2 isoform X3 |
XM_030244457.1 | XP_030100317.1 | non-receptor tyrosine-protein kinase TYK2 isoform X6 |
NM_001205312.1 | NP_001192241.1 | non-receptor tyrosine-protein kinase TYK2 isoform 1 |
NM_018793.2 | NP_061263.2 | non-receptor tyrosine-protein kinase TYK2 isoform 2 |
XM_011242579.3 | XP_011240881.1 | non-receptor tyrosine-protein kinase TYK2 isoform X1 |
XM_006510494.2 | XP_006510557.1 | non-receptor tyrosine-protein kinase TYK2 isoform X5 |
XM_006510493.2 | XP_006510556.1 | non-receptor tyrosine-protein kinase TYK2 isoform X3 |
XM_006510494.1 | XP_006510557.1 | non-receptor tyrosine-protein kinase TYK2 isoform X4 |
XM_006510492.3 | XP_006510555.1 | non-receptor tyrosine-protein kinase TYK2 isoform X2 |
XM_006510492.4 | XP_006510555.1 | non-receptor tyrosine-protein kinase TYK2 isoform X2 |
XM_030244456.1 | XP_030100316.1 | non-receptor tyrosine-protein kinase TYK2 isoform X4 |
TYK2 | XP_001101130.2 | |
Mus musculus (house mouse) | Tyk2 | NP_001192241.1 |
Pan troglodytes (chimpanzee) | TYK2 | XP_001165313.2 |
Rattus norvegicus (Norway rat) | Tyk2 | NP_001244276.1 |
Homo sapiens (human) | TYK2 | NP_003322.3 |
Canis lupus familiaris (dog) | TYK2 | XP_005633269.1 |
Bos taurus (cattle) | TYK2 | NP_001107236.1 |
Xenopus tropicalis (tropical clawed frog) | tyk2 | XP_004918872.1 |
Danio rerio (zebrafish) | tyk2 | XP_003198201.2 |
Loss of Tyrosine Kinase 2 Does Not Affect the Severity of
Yamaji T, Shide K, Kameda T, Sekine M, Kamiunten A, Hidaka T, Kubuki Y, Shimoda H, Abe H, Miike T, Iwakiri H, Tahara Y, Sueta M, Yamamoto S, Hasuike S, Nagata K, Shimoda K
Anticancer research37(7)3841-3847(2017 07)
Kinase Inactive Tyrosine Kinase (Tyk2) Supports Differentiation of Brown Fat Cells.
Raje V, Derecka M, Cantwell M, Meier J, Szczepanek K, Sisler JD, Strobl B, Gamero A, Harris TE, Larner AC
Endocrinology158(1)148-157(2017 Jan)
Re-evaluation of IL-10 signaling reveals novel insights on the contribution of the intracellular domain of the IL-10R2 chain.
Wilbers RHP, van Raaij DR, Westerhof LB, Bakker J, Smant G, Schots A
PloS one12(10)e0186317(2017)
Resolving TYK2 locus genotype-to-phenotype differences in autoimmunity.
Dendrou CA, Cortes A, Shipman L, Evans HG, Attfield KE, Jostins L, Barber T, Kaur G, Kuttikkatte SB, Leach OA, Desel C, Faergeman SL, Cheeseman J, Neville MJ, Sawcer S, Compston A, Johnson AR, Everett C, Bell JI, Karpe F, Ultsch M, Eigenbrot C, McVean G, Fugger L
Science translational medicine8(363)363ra149(2016 Nov)
GeneRIFs: Gene References Into Functions What's a GeneRIF?
Results show that loss of TYK2 does not affect disease severity of JAK2VF-induced murine myeloproliferative neoplasms (MPN) indicating that TYK2 has no cooperative effects with JAK2VF at the onset of MPN.
Title: Loss of Tyrosine Kinase 2 Does Not Affect the Severity of
mutated form which lacks tyrosine kinase activity restores differentiation of brown preadipocytes
Title: Kinase Inactive Tyrosine Kinase (Tyk2) Supports Differentiation of Brown Fat Cells.
TYK2 genetic variants are differentially associated with common autoimmune diseases
Title: Resolving TYK2 locus genotype-to-phenotype differences in autoimmunity.
Tyk2 protects against acute colitis in part by amplifying inflammation-induced epithelial IL-22 signaling to STAT3
Title: Intestinal Epithelial Cell Tyrosine Kinase 2 Transduces IL-22 Signals To Protect from Acute Colitis.
Decreased Tyk2 expression in pancreatic beta cells due to mutation determines susceptibility to virus-induced diabetes mellitus.
Title: Reduced Tyk2 gene expression in ?-cells due to natural mutation determines susceptibility to virus-induced diabetes.
The following Tyk2 gene cDNA ORF clone sequences were retrieved from the NCBI Reference Sequence Database (RefSeq). These sequences represent the protein coding region of the Tyk2 cDNA ORF which is encoded by the open reading frame (ORF) sequence. ORF sequences can be delivered in our standard vector, pcDNA3.1+/C-(K)DYK or the vector of your choice as an expression/transfection-ready ORF clone. Not the clone you want? Click here to find your clone.
CloneID | OMu42324 | |
Clone ID Related Accession (Same CDS sequence) | XM_006510494.2 , XM_006510494.1 | |
Accession Version | XM_006510494.1 | Documents for ORF clone product in default vector |
Sequence Information | ORF Nucleotide Sequence (Length: 2229bp) Protein sequence SNP |
|
Vector | pcDNA3.1-C-(k)DYK or customized vector | User Manual |
Clone information | Clone Map | MSDS |
Tag on pcDNA3.1+/C-(K)DYK | C terminal DYKDDDDK tags | |
ORF Insert Method | CloneEZ™ Seamless cloning technology | |
Insert Structure | linear | |
Update Date | 2016-06-21 | |
Organism | Mus musculus(house mouse) | |
Product | non-receptor tyrosine-protein kinase TYK2 isoform X4 | |
Comment | Comment: MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_000075.6) annotated using gene prediction method: Gnomon, supported by mRNA and EST evidence. Also see: Documentation of NCBI's Annotation Process ##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Version :: Mus musculus Annotation Release 106 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 7.1 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END## |
1 | ATGGTGGGGA CCATGCCTCT GTGTGGGCGG AGAGCCATCT TGGAAGACAG CAAGGCAGAT |
The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.
RefSeq | XP_006510557.1 |
CDS | 264..2492 |
Translation |
Target ORF information:
Target ORF information:
|
XM_006510494.1 |
1 | ATGGTGGGGA CCATGCCTCT GTGTGGGCGG AGAGCCATCT TGGAAGACAG CAAGGCAGAT |
The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.
CloneID | OMu42324 | |
Clone ID Related Accession (Same CDS sequence) | XM_006510494.2 , XM_006510494.1 | |
Accession Version | XM_006510494.2 Latest version! | Documents for ORF clone product in default vector |
Sequence Information | ORF Nucleotide Sequence (Length: 2229bp) Protein sequence SNP |
|
Vector | pcDNA3.1-C-(k)DYK or customized vector | User Manual |
Clone information | Clone Map | MSDS |
Tag on pcDNA3.1+/C-(K)DYK | C terminal DYKDDDDK tags | |
ORF Insert Method | CloneEZ™ Seamless cloning technology | |
Insert Structure | linear | |
Update Date | 2019-08-07 | |
Organism | Mus musculus(house mouse) | |
Product | non-receptor tyrosine-protein kinase TYK2 isoform X5 | |
Comment | Comment: MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_000075.6) annotated using gene prediction method: Gnomon, supported by mRNA and EST evidence. Also see: Documentation of NCBI's Annotation Process On Aug 8, 2019 this sequence version replaced XM_006510494.1. ##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Name :: Mus musculus Annotation Release 108 Annotation Version :: 108 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 8.2 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END## |
1 | ATGGTGGGGA CCATGCCTCT GTGTGGGCGG AGAGCCATCT TGGAAGACAG CAAGGCAGAT |
The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.
RefSeq | XP_006510557.1 |
CDS | 387..2615 |
Translation |
Target ORF information:
Target ORF information:
|
XM_006510494.2 |
1 | ATGGTGGGGA CCATGCCTCT GTGTGGGCGG AGAGCCATCT TGGAAGACAG CAAGGCAGAT |
The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.
CloneID | OMu90219 | |
Clone ID Related Accession (Same CDS sequence) | XM_030244456.1 | |
Accession Version | XM_030244456.1 Latest version! | Documents for ORF clone product in default vector |
Sequence Information | ORF Nucleotide Sequence (Length: 2781bp) Protein sequence SNP |
|
Vector | pcDNA3.1-C-(k)DYK or customized vector | User Manual |
Clone information | Clone Map | MSDS |
Tag on pcDNA3.1+/C-(K)DYK | C terminal DYKDDDDK tags | |
ORF Insert Method | CloneEZ™ Seamless cloning technology | |
Insert Structure | linear | |
Update Date | 2019-08-07 | |
Organism | Mus musculus(house mouse) | |
Product | non-receptor tyrosine-protein kinase TYK2 isoform X4 | |
Comment | Comment: MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_000075.6) annotated using gene prediction method: Gnomon, supported by mRNA and EST evidence. Also see: Documentation of NCBI's Annotation Process ##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Name :: Mus musculus Annotation Release 108 Annotation Version :: 108 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 8.2 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END## |
1 | ATGGTGAAGT ACTTGGCTAC CCTGGAGCGG CTGGCTCCGC GCTTTGGCTC AGAGCGCATA |
The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.
RefSeq | XP_030100316.1 |
CDS | 864..3644 |
Translation |
Target ORF information:
Target ORF information:
|
XM_030244456.1 |
1 | ATGGTGAAGT ACTTGGCTAC CCTGGAGCGG CTGGCTCCGC GCTTTGGCTC AGAGCGCATA |
The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.
CloneID | OMu90220 | |
Clone ID Related Accession (Same CDS sequence) | XM_030244457.1 | |
Accession Version | XM_030244457.1 Latest version! | Documents for ORF clone product in default vector |
Sequence Information | ORF Nucleotide Sequence (Length: 2193bp) Protein sequence SNP |
|
Vector | pcDNA3.1-C-(k)DYK or customized vector | User Manual |
Clone information | Clone Map | MSDS |
Tag on pcDNA3.1+/C-(K)DYK | C terminal DYKDDDDK tags | |
ORF Insert Method | CloneEZ™ Seamless cloning technology | |
Insert Structure | linear | |
Update Date | 2019-08-07 | |
Organism | Mus musculus(house mouse) | |
Product | non-receptor tyrosine-protein kinase TYK2 isoform X6 | |
Comment | Comment: MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_000075.6) annotated using gene prediction method: Gnomon, supported by mRNA and EST evidence. Also see: Documentation of NCBI's Annotation Process ##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Name :: Mus musculus Annotation Release 108 Annotation Version :: 108 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 8.2 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END## |
1 | ATGGATCCGT TTGTACAGGC CAAGCTGTGG CCAGAGGACG GCCTCTACCT GATTCAGTGG |
The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.
RefSeq | XP_030100317.1 |
CDS | 653..2845 |
Translation |
Target ORF information:
Target ORF information:
|
XM_030244457.1 |
1 | ATGGATCCGT TTGTACAGGC CAAGCTGTGG CCAGAGGACG GCCTCTACCT GATTCAGTGG |
The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.
CloneID | OMu20896 | |
Clone ID Related Accession (Same CDS sequence) | XM_011242579.2 , NM_018793.2 , XM_011242579.3 | |
Accession Version | NM_018793.2 Latest version! | Documents for ORF clone product in default vector |
Sequence Information | ORF Nucleotide Sequence (Length: 3555bp) Protein sequence SNP |
|
Vector | pcDNA3.1-C-(k)DYK or customized vector | User Manual |
Clone information | Clone Map | MSDS |
Tag on pcDNA3.1+/C-(K)DYK | C terminal DYKDDDDK tags | |
ORF Insert Method | CloneEZ™ Seamless cloning technology | |
Insert Structure | linear | |
Update Date | 2019-12-15 | |
Organism | Mus musculus(house mouse) | |
Product | non-receptor tyrosine-protein kinase TYK2 isoform 2 | |
Comment | Comment: VALIDATED REFSEQ: This record has undergone validation or preliminary review. The reference sequence was derived from AC163637.4, AK171609.1, BC094240.1 and BC053021.1. On Mar 22, 2007 this sequence version replaced NM_018793.1. Transcript Variant: This variant (2) uses an alternate in-frame splice site in the 3' coding region, compared to variant 1. This results in a shorter protein (isoform 2), compared to isoform 1. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Gene record to access additional publications. ##Evidence-Data-START## Transcript exon combination :: AK167726.1, AK159303.1 [ECO:0000332] RNAseq introns :: mixed/partial sample support SAMN00849374, SAMN00849375 [ECO:0000350] ##Evidence-Data-END## |
1 | ATGGTGGGGA CCATGCCTCT GTGTGGGCGG AGAGCCATCT TGGAAGACAG CAAGGCAGAT |
The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.
RefSeq | NP_061263.2 |
CDS | 269..3823 |
Translation |
Target ORF information:
Target ORF information:
|
NM_018793.2 |
1 | ATGGTGGGGA CCATGCCTCT GTGTGGGCGG AGAGCCATCT TGGAAGACAG CAAGGCAGAT |
The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.
CloneID | OMu20896 | |
Clone ID Related Accession (Same CDS sequence) | XM_011242579.2 , NM_018793.2 , XM_011242579.3 | |
Accession Version | XM_011242579.2 | Documents for ORF clone product in default vector |
Sequence Information | ORF Nucleotide Sequence (Length: 3555bp) Protein sequence SNP |
|
Vector | pcDNA3.1-C-(k)DYK or customized vector | User Manual |
Clone information | Clone Map | MSDS |
Tag on pcDNA3.1+/C-(K)DYK | C terminal DYKDDDDK tags | |
ORF Insert Method | CloneEZ™ Seamless cloning technology | |
Insert Structure | linear | |
Update Date | 2016-06-21 | |
Organism | Mus musculus(house mouse) | |
Product | non-receptor tyrosine-protein kinase TYK2 isoform X1 | |
Comment | Comment: MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_000075.6) annotated using gene prediction method: Gnomon, supported by mRNA and EST evidence. Also see: Documentation of NCBI's Annotation Process On Jun 22, 2016 this sequence version replaced XM_011242579.1. ##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Version :: Mus musculus Annotation Release 106 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 7.1 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END## |
1 | ATGGTGGGGA CCATGCCTCT GTGTGGGCGG AGAGCCATCT TGGAAGACAG CAAGGCAGAT |
The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.
RefSeq | XP_011240881.1 |
CDS | 225..3779 |
Translation |
Target ORF information:
Target ORF information:
|
XM_011242579.2 |
1 | ATGGTGGGGA CCATGCCTCT GTGTGGGCGG AGAGCCATCT TGGAAGACAG CAAGGCAGAT |
The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.
CloneID | OMu42323 | |
Clone ID Related Accession (Same CDS sequence) | XM_030244455.1 , XM_006510493.2 | |
Accession Version | XM_006510493.2 Latest version! | Documents for ORF clone product in default vector |
Sequence Information | ORF Nucleotide Sequence (Length: 3066bp) Protein sequence SNP |
|
Vector | pcDNA3.1-C-(k)DYK or customized vector | User Manual |
Clone information | Clone Map | MSDS |
Tag on pcDNA3.1+/C-(K)DYK | C terminal DYKDDDDK tags | |
ORF Insert Method | CloneEZ™ Seamless cloning technology | |
Insert Structure | linear | |
Update Date | 2016-06-21 | |
Organism | Mus musculus(house mouse) | |
Product | non-receptor tyrosine-protein kinase TYK2 isoform X3 | |
Comment | Comment: MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_000075.6) annotated using gene prediction method: Gnomon, supported by mRNA and EST evidence. Also see: Documentation of NCBI's Annotation Process On Feb 9, 2015 this sequence version replaced XM_006510493.1. ##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Version :: Mus musculus Annotation Release 106 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 7.1 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END## |
1 | ATGAACGATG TGGTGTCTCT GCGGGACCTG TCTAGCGAGG AGGAGATCCA CCACTTTAAG |
The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.
RefSeq | XP_006510556.1 |
CDS | 105..3170 |
Translation |
Target ORF information:
Target ORF information:
|
XM_006510493.2 |
1 | ATGAACGATG TGGTGTCTCT GCGGGACCTG TCTAGCGAGG AGGAGATCCA CCACTTTAAG |
The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.
CloneID | OMu20896 | |
Clone ID Related Accession (Same CDS sequence) | XM_011242579.2 , NM_018793.2 , XM_011242579.3 | |
Accession Version | XM_011242579.3 Latest version! | Documents for ORF clone product in default vector |
Sequence Information | ORF Nucleotide Sequence (Length: 3555bp) Protein sequence SNP |
|
Vector | pcDNA3.1-C-(k)DYK or customized vector | User Manual |
Clone information | Clone Map | MSDS |
Tag on pcDNA3.1+/C-(K)DYK | C terminal DYKDDDDK tags | |
ORF Insert Method | CloneEZ™ Seamless cloning technology | |
Insert Structure | linear | |
Update Date | 2019-08-07 | |
Organism | Mus musculus(house mouse) | |
Product | non-receptor tyrosine-protein kinase TYK2 isoform X1 | |
Comment | Comment: MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_000075.6) annotated using gene prediction method: Gnomon, supported by mRNA and EST evidence. Also see: Documentation of NCBI's Annotation Process On Aug 8, 2019 this sequence version replaced XM_011242579.2. ##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Name :: Mus musculus Annotation Release 108 Annotation Version :: 108 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 8.2 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END## |
1 | ATGGTGGGGA CCATGCCTCT GTGTGGGCGG AGAGCCATCT TGGAAGACAG CAAGGCAGAT |
The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.
RefSeq | XP_011240881.1 |
CDS | 240..3794 |
Translation |
Target ORF information:
Target ORF information:
|
XM_011242579.3 |
1 | ATGGTGGGGA CCATGCCTCT GTGTGGGCGG AGAGCCATCT TGGAAGACAG CAAGGCAGAT |
The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.
CloneID | OMu42322 | |
Clone ID Related Accession (Same CDS sequence) | XM_006510492.3 , XM_006510492.4 | |
Accession Version | XM_006510492.4 Latest version! | Documents for ORF clone product in default vector |
Sequence Information | ORF Nucleotide Sequence (Length: 3243bp) Protein sequence SNP |
|
Vector | pcDNA3.1-C-(k)DYK or customized vector | User Manual |
Clone information | Clone Map | MSDS |
Tag on pcDNA3.1+/C-(K)DYK | C terminal DYKDDDDK tags | |
ORF Insert Method | CloneEZ™ Seamless cloning technology | |
Insert Structure | linear | |
Update Date | 2019-08-07 | |
Organism | Mus musculus(house mouse) | |
Product | non-receptor tyrosine-protein kinase TYK2 isoform X2 | |
Comment | Comment: MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_000075.6) annotated using gene prediction method: Gnomon, supported by mRNA and EST evidence. Also see: Documentation of NCBI's Annotation Process On Aug 8, 2019 this sequence version replaced XM_006510492.3. ##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Name :: Mus musculus Annotation Release 108 Annotation Version :: 108 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 8.2 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END## |
1 | ATGGTGGGGA CCATGCCTCT GTGTGGGCGG AGAGCCATCT TGGAAGACAG CAAGGCAGAT |
The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.
RefSeq | XP_006510555.1 |
CDS | 254..3496 |
Translation |
Target ORF information:
Target ORF information:
|
XM_006510492.4 |
1 | ATGGTGGGGA CCATGCCTCT GTGTGGGCGG AGAGCCATCT TGGAAGACAG CAAGGCAGAT |
The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.
CloneID | OMu42323 | |
Clone ID Related Accession (Same CDS sequence) | XM_030244455.1 , XM_006510493.2 | |
Accession Version | XM_030244455.1 Latest version! | Documents for ORF clone product in default vector |
Sequence Information | ORF Nucleotide Sequence (Length: 3066bp) Protein sequence SNP |
|
Vector | pcDNA3.1-C-(k)DYK or customized vector | User Manual |
Clone information | Clone Map | MSDS |
Tag on pcDNA3.1+/C-(K)DYK | C terminal DYKDDDDK tags | |
ORF Insert Method | CloneEZ™ Seamless cloning technology | |
Insert Structure | linear | |
Update Date | 2019-08-07 | |
Organism | Mus musculus(house mouse) | |
Product | non-receptor tyrosine-protein kinase TYK2 isoform X3 | |
Comment | Comment: MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_000075.6) annotated using gene prediction method: Gnomon, supported by mRNA and EST evidence. Also see: Documentation of NCBI's Annotation Process ##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Name :: Mus musculus Annotation Release 108 Annotation Version :: 108 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 8.2 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END## |
1 | ATGAACGATG TGGTGTCTCT GCGGGACCTG TCTAGCGAGG AGGAGATCCA CCACTTTAAG |
The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.
RefSeq | XP_030100315.1 |
CDS | 613..3678 |
Translation |
Target ORF information:
Target ORF information:
|
XM_030244455.1 |
1 | ATGAACGATG TGGTGTCTCT GCGGGACCTG TCTAGCGAGG AGGAGATCCA CCACTTTAAG |
The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.
CloneID | OMu16270 | |
Clone ID Related Accession (Same CDS sequence) | NM_001205312.1 | |
Accession Version | NM_001205312.1 Latest version! | Documents for ORF clone product in default vector |
Sequence Information | ORF Nucleotide Sequence (Length: 3624bp) Protein sequence SNP |
|
Vector | pcDNA3.1-C-(k)DYK or customized vector | User Manual |
Clone information | Clone Map | MSDS |
Tag on pcDNA3.1+/C-(K)DYK | C terminal DYKDDDDK tags | |
ORF Insert Method | CloneEZ™ Seamless cloning technology | |
Insert Structure | linear | |
Update Date | 2019-12-15 | |
Organism | Mus musculus(house mouse) | |
Product | non-receptor tyrosine-protein kinase TYK2 isoform 1 | |
Comment | Comment: VALIDATED REFSEQ: This record has undergone validation or preliminary review. The reference sequence was derived from AC163637.4. Transcript Variant: This variant (1) represents the longer transcript and encodes the longer isoform (1). Sequence Note: The RefSeq transcript and protein were derived from genomic sequence to make the sequence consistent with the reference genome assembly. The genomic coordinates used for the transcript record were based on transcript alignments. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Gene record to access additional publications. ##Evidence-Data-START## Transcript exon combination :: AK154438.1 [ECO:0000332] RNAseq introns :: mixed/partial sample support SAMN00849374, SAMN00849375 [ECO:0000350] ##Evidence-Data-END## |
1 | ATGGTGGGGA CCATGCCTCT GTGTGGGCGG AGAGCCATCT TGGAAGACAG CAAGGCAGAT |
The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.
RefSeq | NP_001192241.1 |
CDS | 269..3892 |
Translation |
Target ORF information:
Target ORF information:
|
NM_001205312.1 |
1 | ATGGTGGGGA CCATGCCTCT GTGTGGGCGG AGAGCCATCT TGGAAGACAG CAAGGCAGAT |
The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.
CloneID | OMu42322 | |
Clone ID Related Accession (Same CDS sequence) | XM_006510492.3 , XM_006510492.4 | |
Accession Version | XM_006510492.3 | Documents for ORF clone product in default vector |
Sequence Information | ORF Nucleotide Sequence (Length: 3243bp) Protein sequence SNP |
|
Vector | pcDNA3.1-C-(k)DYK or customized vector | User Manual |
Clone information | Clone Map | MSDS |
Tag on pcDNA3.1+/C-(K)DYK | C terminal DYKDDDDK tags | |
ORF Insert Method | CloneEZ™ Seamless cloning technology | |
Insert Structure | linear | |
Update Date | 2016-06-21 | |
Organism | Mus musculus(house mouse) | |
Product | non-receptor tyrosine-protein kinase TYK2 isoform X2 | |
Comment | Comment: MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_000075.6) annotated using gene prediction method: Gnomon, supported by mRNA and EST evidence. Also see: Documentation of NCBI's Annotation Process On Jun 22, 2016 this sequence version replaced XM_006510492.2. ##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Version :: Mus musculus Annotation Release 106 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 7.1 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END## |
1 | ATGGTGGGGA CCATGCCTCT GTGTGGGCGG AGAGCCATCT TGGAAGACAG CAAGGCAGAT |
The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.
RefSeq | XP_006510555.1 |
CDS | 260..3502 |
Translation |
Target ORF information:
Target ORF information:
|
XM_006510492.3 |
1 | ATGGTGGGGA CCATGCCTCT GTGTGGGCGG AGAGCCATCT TGGAAGACAG CAAGGCAGAT |
The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.
Loss of Tyrosine Kinase 2 Does Not Affect the Severity of |
Kinase Inactive Tyrosine Kinase (Tyk2) Supports Differentiation of Brown Fat Cells. |
Re-evaluation of IL-10 signaling reveals novel insights on the contribution of the intracellular domain of the IL-10R2 chain. |
Resolving TYK2 locus genotype-to-phenotype differences in autoimmunity. |