Gene Symbol | Rhog |
Entrez Gene ID | 56212 |
Full Name | ras homolog family member G |
Synonyms | 2810426G09Rik,Arhg,Sid10750 |
General protein information |
|
Gene Type | protein-coding |
Organism | Mus musculus(house mouse) |
Genome |
ORF » Species Summary » Mus musculus » Rhog cDNA ORF clone
gRNAs
Gene Symbol | Rhog |
Entrez Gene ID | 56212 |
Full Name | ras homolog family member G |
Synonyms | 2810426G09Rik,Arhg,Sid10750 |
General protein information |
|
Gene Type | protein-coding |
Organism | Mus musculus(house mouse) |
Genome |
mRNA | Protein | Name |
---|---|---|
NM_019566.3 | NP_062512.1 | rho-related GTP-binding protein RhoG precursor |
Mus musculus (house mouse) | Rhog | NP_062512.1 |
Danio rerio (zebrafish) | rhogb | NP_956334.1 |
Homo sapiens (human) | RHOG | NP_001656.2 |
RHOG | XP_001113546.1 | |
Bos taurus (cattle) | RHOG | NP_001073774.1 |
Gallus gallus (chicken) | LOC100859599 | XP_004939037.1 |
Xenopus tropicalis (tropical clawed frog) | LOC100489878 | XP_004920315.1 |
Canis lupus familiaris (dog) | RHOG | XP_542335.2 |
Rattus norvegicus (Norway rat) | Rhog | NP_001032272.1 |
Deletion of JMJD2B in neurons leads to defective spine maturation, hyperactive behavior and memory deficits in mouse.
Fujiwara K, Fujita Y, Kasai A, Onaka Y, Hashimoto H, Okada H, Yamashita T
Translational psychiatry6e766(2016 Mar)
An ELMO2-RhoG-ILK network modulates microtubule dynamics.
Jackson BC, Ivanova IA, Dagnino L
Molecular biology of the cell26(14)2712-25(2015 Jul)
P-Rex1 directly activates RhoG to regulate GPCR-driven Rac signalling and actin polarity in neutrophils.
Damoulakis G, Gambardella L, Rossman KL, Lawson CD, Anderson KE, Fukui Y, Welch HC, Der CJ, Stephens LR, Hawkins PT
Journal of cell science127(Pt 11)2589-600(2014 Jun)
RhoG protein regulates platelet granule secretion and thrombus formation in mice.
Goggs R, Harper MT, Pope RJ, Savage JS, Williams CM, Mundell SJ, Heesom KJ, Bass M, Mellor H, Poole AW
The Journal of biological chemistry288(47)34217-29(2013 Nov)
GeneRIFs: Gene References Into Functions What's a GeneRIF?
ELMO2-RhoG-ILK complex has a key role in integrin-independent stabilization of the microtubule network in differentiated keratinocytes.
Title: An ELMO2-RhoG-ILK network modulates microtubule dynamics.
RhoG is expressed and activated in platelets, plays an important role in GPVI-Fc receptor gamma-chain complex-mediated platelet activation, and is critical for thrombus formation in vivo.
Title: RhoG protein regulates glycoprotein VI-Fc receptor ?-chain complex-mediated platelet activation and thrombus formation.
RhoG protein regulates platelet granule secretion and thrombus formation in mice.
Title: RhoG protein regulates platelet granule secretion and thrombus formation in mice.
Examined the role of RhoG in the invasive behavior of glioblastoma cells; found that depletion of RhoG strongly inhibits activation of the Rac1 GTPase by both HGF and EGF; also RhoG contributes to the formation of lamellipodia and invadopodia.
Title: The small GTPase RhoG mediates glioblastoma cell invasion.
several Rho family small GTPases activate PI3K by an indirect cooperative positive feedback that required a combination of Rac, CDC42, and RhoG small GTPase activities
Title: Cooperative activation of PI3K by Ras and Rho family small GTPases.
The following Rhog gene cDNA ORF clone sequences were retrieved from the NCBI Reference Sequence Database (RefSeq). These sequences represent the protein coding region of the Rhog cDNA ORF which is encoded by the open reading frame (ORF) sequence. ORF sequences can be delivered in our standard vector, pcDNA3.1+/C-(K)DYK or the vector of your choice as an expression/transfection-ready ORF clone. Not the clone you want? Click here to find your clone.
CloneID | OMu11210 | |
Clone ID Related Accession (Same CDS sequence) | NM_019566.3 | |
Accession Version | NM_019566.3 Latest version! | Documents for ORF clone product in default vector |
Sequence Information | ORF Nucleotide Sequence (Length: 576bp) Protein sequence SNP |
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Vector | pcDNA3.1-C-(k)DYK or customized vector | ![]() |
Clone information | Clone Map | ![]() |
Tag on pcDNA3.1+/C-(K)DYK | C terminal DYKDDDDK tags | |
ORF Insert Method | CloneEZ™ Seamless cloning technology | |
Insert Structure | linear | |
Update Date | 2019-10-19 | |
Organism | Mus musculus(house mouse) | |
Product | rho-related GTP-binding protein RhoG precursor | |
Comment | Comment: VALIDATED REFSEQ: This record has undergone validation or preliminary review. The reference sequence was derived from BQ942269.1 and AK143623.1. On May 22, 2007 this sequence version replaced NM_019566.2. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Gene record to access additional publications. ##Evidence-Data-START## Transcript exon combination :: AK143623.1, AK169853.1 [ECO:0000332] RNAseq introns :: single sample supports all introns SAMN00849374, SAMN00849375 [ECO:0000348] ##Evidence-Data-END## COMPLETENESS: complete on the 3' end. |
1 | ATGCAGAGCA TCAAGTGTGT GGTGGTGGGC GATGGGGCCG TAGGCAAGAC GTGCCTTCTC |
The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.
RefSeq | NP_062512.1 |
CDS | 143..718 |
Translation |
Target ORF information:
Target ORF information:
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1 | ATGCAGAGCA TCAAGTGTGT GGTGGTGGGC GATGGGGCCG TAGGCAAGAC GTGCCTTCTC |
The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.
Deletion of JMJD2B in neurons leads to defective spine maturation, hyperactive behavior and memory deficits in mouse. |
An ELMO2-RhoG-ILK network modulates microtubule dynamics. |
P-Rex1 directly activates RhoG to regulate GPCR-driven Rac signalling and actin polarity in neutrophils. |
RhoG protein regulates platelet granule secretion and thrombus formation in mice. |