×

AATF cDNA ORF clone, Mus musculus(House mouse)

Gene Symbol AATF
Entrez Gene ID 56321
Full Name apoptosis antagonizing transcription factor
Synonyms 4933415H02Rik,5830465M17Rik,Che-1,Trb
General protein information
Preferred Names

apoptosis antagonizing transcription factor

Names

protein AATF
rb-binding protein Che-1
traube protein

Gene Type protein-coding
Organism Mus musculus(House mouse)
Genome

11

11|11 C


mRNA and Protein(s)

mRNA Protein Name
NM_019816.1 NP_062790.1 protein AATF
XM_006533789.3 XP_006533852.1 protein AATF isoform X1
XM_011249153.2 XP_011247455.1 protein AATF isoform X2



Anopheles gambiae (African malaria mosquito) AgaP_AGAP007394 XP_308438.4
Caenorhabditis elegans (roundworm) Y73E7A.2 NP_490870.2
Oryza sativa (rice) Os01g0526200 NP_001043227.1
Xenopus tropicalis (tropical clawed frog) aatf NP_001016308.1
Canis lupus familiaris (dog) AATF XP_005624830.1
Mus musculus (house mouse) Aatf NP_062790.1
Danio rerio (zebrafish) aatf NP_001258768.1
Macaca mulatta (rhesus monkey) AATF XP_001109240.2
Pan troglodytes (chimpanzee) AATF XP_511427.2
Rattus norvegicus (Norway rat) Aatf NP_446172.1
Homo sapiens (human) AATF NP_036270.1
Bos taurus (cattle) AATF XP_002695664.3
Gallus gallus (chicken) AATF NP_001025895.1
Arabidopsis thaliana (thale cress) AT5G61330 NP_200941.2


Related articles in PubMed

Nucleolar AATF regulates c-Jun-mediated apoptosis.
Ferraris SE, Isoniemi K, Torvaldson E, Anckar J, Westermarck J, Eriksson JE
Molecular biology of the cell23(21)4323-32(2012 Nov)

AATF mediates an antiapoptotic effect of the unfolded protein response through transcriptional regulation of AKT1.
Ishigaki S, Fonseca SG, Oslowski CM, Jurczyk A, Shearstone JR, Zhu LJ, Permutt MA, Greiner DL, Bortell R, Urano F
Cell death and differentiation17(5)774-86(2010 May)

Resolution of cell fate decisions revealed by single-cell gene expression analysis from zygote to blastocyst.
Guo G, Huss M, Tong GQ, Wang C, Li Sun L, Clarke ND, Robson P
Developmental cell18(4)675-85(2010 Apr)

A systems approach reveals that the myogenesis genome network is regulated by the transcriptional repressor RP58.
Yokoyama S, Ito Y, Ueno-Kudoh H, Shimizu H, Uchibe K, Albini S, Mitsuoka K, Miyaki S, Kiso M, Nagai A, Hikata T, Osada T, Fukuda N, Yamashita S, Harada D, Mezzano V, Kasai M, Puri PL, Hayashizaki Y, Okado H, Hashimoto M, Asahara H
Developmental cell17(6)836-48(2009 Dec)

NRAGE associates with the anti-apoptotic factor Che-1 and regulates its degradation to induce cell death.
Di Certo MG, Corbi N, Bruno T, Iezzi S, De Nicola F, Desantis A, Ciotti MT, Mattei E, Floridi A, Fanciulli M, Passananti C
Journal of cell science120(Pt 11)1852-8(2007 Jun)

GeneRIFs: Gene References Into Functions What's a GeneRIF?

we found that object recognition memory persistence at 7days was impaired in Che-1(+/-) heterozygous mice. This is the first evidence showing that Che-1 is involved in memory processes.
Title: Heterozygous Che-1 KO mice show deficiencies in object recognition memory persistence.

These results identify AATF as a nucleolar-confined c-Jun cofactor whose expression levels and spatial distribution determine the stress-induced activity of c-Jun and the levels of c-Jun-mediated apoptosis.
Title: Nucleolar AATF regulates c-Jun-mediated apoptosis.

Che-1 as a new Pin1 and HDM2 target and confirm its important role in the cellular response to DNA damage.
Title: The prolyl isomerase Pin1 affects Che-1 stability in response to apoptotic DNA damage.

AATF is an endogenous antagonist of Par-4 activity and an effective inhibitor of aberrant amyloid beta 1-42 production and secretion under apoptotic conditions.
Title: AATF inhibits aberrant production of amyloid beta peptide 1-42 by interacting directly with Par-4.

The following AATF gene cDNA ORF clone sequences were retrieved from the NCBI Reference Sequence Database (RefSeq). These sequences represent the protein coding region of the AATF cDNA ORF which is encoded by the open reading frame (ORF) sequence. ORF sequences can be delivered in our standard vector, pcDNA3.1+/C-(K)DYK or the vector of your choice as an expression/transfection-ready ORF clone. Not the clone you want? Click here to find your clone.

***CloneID RefSeq Accession Definition **Vector *Turnaround time Price (USD) Select
OMu11318 NM_019816.1
Latest version!
Mus musculus apoptosis antagonizing transcription factor (Aatf), mRNA. pcDNA3.1+/C-(K)DYK or customized vector
in pcDNA3.1+/C-(K)DYK
$219.50-$307.30
$439.00
OMu46653 XM_006533789.3
Latest version!
Mus musculus apoptosis antagonizing transcription factor (Aatf), transcript variant X3, mRNA. pcDNA3.1+/C-(K)DYK or customized vector 7-9 $223.30
$319.00
OMu69636 XM_011249153.2
Latest version!
Mus musculus apoptosis antagonizing transcription factor (Aatf), transcript variant X4, mRNA. pcDNA3.1+/C-(K)DYK or customized vector 7-9 $223.30
$319.00

ORF Online Only Promotion

Next-day Shipping ORF Clones ( in default vector with tag)
1 Clone 30% OFF
2-4 Clone 40% OFF
5 or more Clone 50% OFF
All Other ORF Clones
30% OFF

*Business Day

** You may select a custom vector to replace pcDNA3.1+/C-(K)DYK after clone is added to cart.

** GenScript guarantees 100% sequence accuracy of all synthetic DNA constructs we deliver, but we do not guarantee protein expression in your experimental system. Protein expression is influenced by many factors that may vary between experiments or laboratories. In addition, please pay attention to the signal peptide, propeptide and transit peptide in target ORF, which may affect the choice of vector (N/C terminal tag vector).

***One clone ID might be correlated to multiple accession numbers, which share the same CDS sequence.


CloneID OMu11318
Clone ID Related Accession (Same CDS sequence) NM_019816.1
Accession Version NM_019816.1 Latest version! Documents for ORF clone product in dufault vector
Sequence Information ORF Nucleotide Sequence (Length: 1581bp)
Protein sequence
SNP
Vector pcDNA3.1+/C-(K)DYK or customized vector User Manual
Clone information Clone Map MSDS
Tag on pcDNA3.1+/C-(K)DYK C terminal DYKDDDDK tags COA
ORF Insert Method CloneEZ® Seamless cloning technology
Insert Structure linear
Update Date 2016-09-09
Organism Mus musculus(House mouse)
Product protein AATF
Comment VALIDATED REFSEQ: This record has undergone validation or preliminary review. The reference sequence was derived from AF222801.1. On Dec 7, 2005 this sequence version replaced XM_914034.1. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Gene record to access additional publications. ##Evidence-Data-START## Transcript exon combination :: AF222801.1, AK141334.1 [ECO:0000332] RNAseq introns :: mixed/partial sample support SAMN00849374, SAMN00849375 [ECO:0000350] ##Evidence-Data-END##

1
61
121
181
241
301
361
421
481
541
601
661
721
781
841
901
961
1021
1081
1141
1201
1261
1321
1381
1441
1501
1561
ATGGCGGCGC CGCAGCCCTT GGCTCTGCAG CTGGAACAGT TGCTGAATCC GAGACCGCGT 
GAGGCGGATC CTGAGGCCGA CCCGGAGGAG GCCACTAGAG CCAGAGTGAT TGACAGGTTT
GATGAAGGGG AAGAGGAGAA AGATGATCTG GCAGTGAGTA GCATTAGAAA GTTGGCACCA
GTCTCCCTCT TGGACACCGA CAAAAGGTAT TCTGGCAAGA CCACTTCTAG GAAAGCTTGG
AAAGAAGACC ATTGGGAGCA GGCTCTGCCA AGTTCATCTG ATAACGAAGC ATCTGATGAG
GGAGGATCTG AAGATGGGGA TTCAGAGGGC CTGGGCCTGG AGGAGATCTC AGAAGATGTT
GACGAAGACT TAGAAGACAA CAAAATATCT GATGAGGGAG GATCTGAAGA TGGGGATTCA
GAGGGCCTGG GCCTGGAAGA GTTCTCAGAA GATGTTGAGG AGGACTTAGA AGGTGAGGAT
GAGGAAGACA GAGAAGAAGA CAGGAACAGT GAAGATGATG GTGTGGTGGC AGCCTTCTCC
AGTGTCAAAG TTTCTGAGGA AGTGGAAAAA GGAAGAGCTG TGAAGAATCA GATAGCATTG
TGGGACCAGC TCTTGGAAGG AAGGATCAAG CTACAAAAAG CTCTCTTGAC TACCAATCAG
TTGCCTCAAC CAGATGTTTT CCCTGTCTTC AAGGACAAAG GTGGCCCAGA ATTTGCCAGT
GCTCTGAAAA ATAGTCACAA AGCACTTAAA GCCTTGTTAA GGTCATTGGT GGATCTTCAG
GAAGAGTTGC TTTTCCAGTA CCCAGACACG AGACATATAG TAAATGGGGC GAAACCCAAT
ACAGAGAGTG AGGAGATTTC CAGTGAAGAT GATGAGCTAG TGGGAGAGAA GAAGAAACAA
CGAAAGGCCC CACCCAAGAG GAAGCTAGAG ATGGAGGACT ATCCCAGCTT CATGGCAAAG
CGCTTTGCTG ACTTCACCAT CTATAGGAAT CACACACTAC AGAAATGGCA TGATAAAACC
AAGCTTGCTT CTGGAAAACT GGGCAAGGGT TTTGGTGCCT TCGAACGCTC GATCTTGACT
CAGATCGATC ATATCATGAT GGACAAAGAA AGATTGCTTC GGAGGACACA GACCAAGCGC
TCTGCCTACC GAGTTCTTGG CAAACCGGAG CCAGTCCCTG AGCCTGTTGC AGAGACCTTG
CCAGGAGAAC CAGAGACGCT TCCTCAGGGC CCTGCCAATG CCCACCTGAG GGACTTGGAT
GAGGAGATAT TTGATGATGA TGACTTTTAC CACCAGCTCC TTCGAGAACT CATAGAGCGG
AAAACCAGCT CTTTGGATCC AAATGATCAG GTGGCCATGG GAAGGCAGTG GCTTGCAATC
CAGAAACTAC GAAGCAAAAT CCGCAAGAAG GTAGATAGAA AAGCCAGCAA AGGAAGGAAA
CTTCGGTTCC ATGTCCTTAG CAAGCTCCTG AGTTTCATGG CACCTATTGA CCACACCGCA
ATGAGTGATG ATGCCAGGAC GGAGTTGTTT CGATCTCTTT TCGGCCAGCT CAACCCTCCT
GATGCAGACC GTGGGAAGTG A

The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.

RefSeq NP_062790.1
CDS120..1700
Misc Feature(1)123..125
Misc Feature(2)303..305
Misc Feature(3)627..629
Misc Feature(4)681..1136
Misc Feature(5)837..965
Misc Feature(6)837..839
Misc Feature(7)966..1133
Misc Feature(8)966..968
Misc Feature(9)978..980
Misc Feature(10)981..983
Misc Feature(11)1134..1433
Misc Feature(12)1407..1661
Exon (1)1..210
Exon (2)211..399
Exon (3)400..495
Exon (4)496..714
Exon (5)715..852
Exon (6)853..967
Exon (7)968..1166
Exon (8)1167..1331
Exon (9)1332..1415
Exon (10)1416..1483
Exon (11)1484..1564
Exon (12)1565..1636
Exon (13)1637..1800
Translation

Target ORF information:

RefSeq Version NM_019816.1
Organism Mus musculus(House mouse)
Definition Mus musculus apoptosis antagonizing transcription factor (Aatf), mRNA.

Target ORF information:

Epitope DYKDDDDK
Bacterial selection AMPR
Mammalian selection NeoR
Vector pcDNA3.1+/C-(K)DYK
NM_019816.1

ORF Insert Sequence:

1
61
121
181
241
301
361
421
481
541
601
661
721
781
841
901
961
1021
1081
1141
1201
1261
1321
1381
1441
1501
1561
ATGGCGGCGC CGCAGCCCTT GGCTCTGCAG CTGGAACAGT TGCTGAATCC GAGACCGCGT 
GAGGCGGATC CTGAGGCCGA CCCGGAGGAG GCCACTAGAG CCAGAGTGAT TGACAGGTTT
GATGAAGGGG AAGAGGAGAA AGATGATCTG GCAGTGAGTA GCATTAGAAA GTTGGCACCA
GTCTCCCTCT TGGACACCGA CAAAAGGTAT TCTGGCAAGA CCACTTCTAG GAAAGCTTGG
AAAGAAGACC ATTGGGAGCA GGCTCTGCCA AGTTCATCTG ATAACGAAGC ATCTGATGAG
GGAGGATCTG AAGATGGGGA TTCAGAGGGC CTGGGCCTGG AGGAGATCTC AGAAGATGTT
GACGAAGACT TAGAAGACAA CAAAATATCT GATGAGGGAG GATCTGAAGA TGGGGATTCA
GAGGGCCTGG GCCTGGAAGA GTTCTCAGAA GATGTTGAGG AGGACTTAGA AGGTGAGGAT
GAGGAAGACA GAGAAGAAGA CAGGAACAGT GAAGATGATG GTGTGGTGGC AGCCTTCTCC
AGTGTCAAAG TTTCTGAGGA AGTGGAAAAA GGAAGAGCTG TGAAGAATCA GATAGCATTG
TGGGACCAGC TCTTGGAAGG AAGGATCAAG CTACAAAAAG CTCTCTTGAC TACCAATCAG
TTGCCTCAAC CAGATGTTTT CCCTGTCTTC AAGGACAAAG GTGGCCCAGA ATTTGCCAGT
GCTCTGAAAA ATAGTCACAA AGCACTTAAA GCCTTGTTAA GGTCATTGGT GGATCTTCAG
GAAGAGTTGC TTTTCCAGTA CCCAGACACG AGACATATAG TAAATGGGGC GAAACCCAAT
ACAGAGAGTG AGGAGATTTC CAGTGAAGAT GATGAGCTAG TGGGAGAGAA GAAGAAACAA
CGAAAGGCCC CACCCAAGAG GAAGCTAGAG ATGGAGGACT ATCCCAGCTT CATGGCAAAG
CGCTTTGCTG ACTTCACCAT CTATAGGAAT CACACACTAC AGAAATGGCA TGATAAAACC
AAGCTTGCTT CTGGAAAACT GGGCAAGGGT TTTGGTGCCT TCGAACGCTC GATCTTGACT
CAGATCGATC ATATCATGAT GGACAAAGAA AGATTGCTTC GGAGGACACA GACCAAGCGC
TCTGCCTACC GAGTTCTTGG CAAACCGGAG CCAGTCCCTG AGCCTGTTGC AGAGACCTTG
CCAGGAGAAC CAGAGACGCT TCCTCAGGGC CCTGCCAATG CCCACCTGAG GGACTTGGAT
GAGGAGATAT TTGATGATGA TGACTTTTAC CACCAGCTCC TTCGAGAACT CATAGAGCGG
AAAACCAGCT CTTTGGATCC AAATGATCAG GTGGCCATGG GAAGGCAGTG GCTTGCAATC
CAGAAACTAC GAAGCAAAAT CCGCAAGAAG GTAGATAGAA AAGCCAGCAA AGGAAGGAAA
CTTCGGTTCC ATGTCCTTAG CAAGCTCCTG AGTTTCATGG CACCTATTGA CCACACCGCA
ATGAGTGATG ATGCCAGGAC GGAGTTGTTT CGATCTCTTT TCGGCCAGCT CAACCCTCCT
GATGCAGACC GTGGGAAGTG A

The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.

CloneID OMu46653
Clone ID Related Accession (Same CDS sequence) XM_006533789.3
Accession Version XM_006533789.3 Latest version! Documents for ORF clone product in dufault vector
Sequence Information ORF Nucleotide Sequence (Length: 1485bp)
Protein sequence
SNP
Vector pcDNA3.1+/C-(K)DYK or customized vector User Manual
Clone information Clone Map MSDS
Tag on pcDNA3.1+/C-(K)DYK C terminal DYKDDDDK tags
ORF Insert Method CloneEZ® Seamless cloning technology
Insert Structure linear
Update Date 2016-06-22
Organism Mus musculus(House mouse)
Product protein AATF isoform X1
Comment MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_000077.6) annotated using gene prediction method: Gnomon, supported by EST evidence. Also see: Documentation of NCBI's Annotation Process On Jun 22, 2016 this sequence version replaced XM_006533789.2. ##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Version :: Mus musculus Annotation Release 106 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 7.1 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END##

1
61
121
181
241
301
361
421
481
541
601
661
721
781
841
901
961
1021
1081
1141
1201
1261
1321
1381
1441
ATGGCGGCGC CGCAGCCCTT GGCTCTGCAG CTGGAACAGT TGCTGAATCC GAGACCGCGT 
GAGGCGGATC CTGAGGCCGA CCCGGAGGAG GCCACTAGAG CCAGAGTGAT TGACAGGTTT
GATGAAGGGG AAGAGGAGAA AGATGATCTG GCAGTGAGTA GCATTAGAAA GTTGGCACCA
GTCTCCCTCT TGGACACCGA CAAAAGGTAT TCTGGCAAGA CCACTTCTAG GAAAGCTTGG
AAAGAAGACC ATTGGGAGCA GGCTCTGCCA AGTTCATCTG ACAACAAAAT ATCTGATGAG
GGAGGATCTG AAGATGGGGA TTCAGAGGGC CTGGGCCTGG AAGAGTTCTC AGAAGATGTT
GAGGAGGACT TAGAAGGTGA GGATGAGGAA GACAGAGAAG AAGACAGGAA CAGTGAAGAT
GATGGTGTGG TGGCAGCCTT CTCCAGTGTC AAAGTTTCTG AGGAAGTGGA AAAAGGAAGA
GCTGTGAAGA ATCAGATAGC ATTGTGGGAC CAGCTCTTGG AAGGAAGGAT CAAGCTACAA
AAAGCTCTCT TGACTACCAA TCAGTTGCCT CAACCAGATG TTTTCCCTGT CTTCAAGGAC
AAAGGTGGCC CAGAATTTGC CAGTGCTCTG AAAAATAGTC ACAAAGCACT TAAAGCCTTG
TTAAGGTCAT TGGTGGATCT TCAGGAAGAG TTGCTTTTCC AGTACCCAGA CACGAGACAT
ATAGTAAATG GGGCGAAACC CAATACAGAG AGTGAGGAGA TTTCCAGTGA AGATGATGAG
CTAGTGGGAG AGAAGAAGAA ACAACGAAAG GCCCCACCCA AGAGGAAGCT AGAGATGGAG
GACTATCCCA GCTTCATGGC AAAGCGCTTT GCTGACTTCA CCATCTATAG GAATCACACA
CTACAGAAAT GGCATGATAA AACCAAGCTT GCTTCTGGAA AACTGGGCAA GGGTTTTGGT
GCCTTCGAAC GCTCGATCTT GACTCAGATC GATCATATCA TGATGGACAA AGAAAGATTG
CTTCGGAGGA CACAGACCAA GCGCTCTGCC TACCGAGTTC TTGGCAAACC GGAGCCAGTC
CCTGAGCCTG TTGCAGAGAC CTTGCCAGGA GAACCAGAGA CGCTTCCTCA GGGCCCTGCC
AATGCCCACC TGAGGGACTT GGATGAGGAG ATATTTGATG ATGATGACTT TTACCACCAG
CTCCTTCGAG AACTCATAGA GCGGAAAACC AGCTCTTTGG ATCCAAATGA TCAGGTGGCC
ATGGGAAGGC AGTGGCTTGC AATCCAGAAA CTACGAAGCA AAATCCGCAA GAAGGTAGAT
AGAAAAGCCA GCAAAGGAAG GAAACTTCGG TTCCATGTCC TTAGCAAGCT CCTGAGTTTC
ATGGCACCTA TTGACCACAC CGCAATGAGT GATGATGCCA GGACGGAGTT GTTTCGATCT
CTTTTCGGCC AGCTCAACCC TCCTGATGCA GACCGTGGGA AGTGA

The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.

RefSeq XP_006533852.1
CDS182..1666
Misc Feature(1)647..1102
Misc Feature(2)1373..1627
Translation

Target ORF information:

RefSeq Version XM_006533789.3
Organism Mus musculus(House mouse)
Definition Mus musculus apoptosis antagonizing transcription factor (Aatf), transcript variant X3, mRNA.

Target ORF information:

Epitope DYKDDDDK
Bacterial selection AMPR
Mammalian selection NeoR
Vector pcDNA3.1+/C-(K)DYK
XM_006533789.3

ORF Insert Sequence:

1
61
121
181
241
301
361
421
481
541
601
661
721
781
841
901
961
1021
1081
1141
1201
1261
1321
1381
1441
ATGGCGGCGC CGCAGCCCTT GGCTCTGCAG CTGGAACAGT TGCTGAATCC GAGACCGCGT 
GAGGCGGATC CTGAGGCCGA CCCGGAGGAG GCCACTAGAG CCAGAGTGAT TGACAGGTTT
GATGAAGGGG AAGAGGAGAA AGATGATCTG GCAGTGAGTA GCATTAGAAA GTTGGCACCA
GTCTCCCTCT TGGACACCGA CAAAAGGTAT TCTGGCAAGA CCACTTCTAG GAAAGCTTGG
AAAGAAGACC ATTGGGAGCA GGCTCTGCCA AGTTCATCTG ACAACAAAAT ATCTGATGAG
GGAGGATCTG AAGATGGGGA TTCAGAGGGC CTGGGCCTGG AAGAGTTCTC AGAAGATGTT
GAGGAGGACT TAGAAGGTGA GGATGAGGAA GACAGAGAAG AAGACAGGAA CAGTGAAGAT
GATGGTGTGG TGGCAGCCTT CTCCAGTGTC AAAGTTTCTG AGGAAGTGGA AAAAGGAAGA
GCTGTGAAGA ATCAGATAGC ATTGTGGGAC CAGCTCTTGG AAGGAAGGAT CAAGCTACAA
AAAGCTCTCT TGACTACCAA TCAGTTGCCT CAACCAGATG TTTTCCCTGT CTTCAAGGAC
AAAGGTGGCC CAGAATTTGC CAGTGCTCTG AAAAATAGTC ACAAAGCACT TAAAGCCTTG
TTAAGGTCAT TGGTGGATCT TCAGGAAGAG TTGCTTTTCC AGTACCCAGA CACGAGACAT
ATAGTAAATG GGGCGAAACC CAATACAGAG AGTGAGGAGA TTTCCAGTGA AGATGATGAG
CTAGTGGGAG AGAAGAAGAA ACAACGAAAG GCCCCACCCA AGAGGAAGCT AGAGATGGAG
GACTATCCCA GCTTCATGGC AAAGCGCTTT GCTGACTTCA CCATCTATAG GAATCACACA
CTACAGAAAT GGCATGATAA AACCAAGCTT GCTTCTGGAA AACTGGGCAA GGGTTTTGGT
GCCTTCGAAC GCTCGATCTT GACTCAGATC GATCATATCA TGATGGACAA AGAAAGATTG
CTTCGGAGGA CACAGACCAA GCGCTCTGCC TACCGAGTTC TTGGCAAACC GGAGCCAGTC
CCTGAGCCTG TTGCAGAGAC CTTGCCAGGA GAACCAGAGA CGCTTCCTCA GGGCCCTGCC
AATGCCCACC TGAGGGACTT GGATGAGGAG ATATTTGATG ATGATGACTT TTACCACCAG
CTCCTTCGAG AACTCATAGA GCGGAAAACC AGCTCTTTGG ATCCAAATGA TCAGGTGGCC
ATGGGAAGGC AGTGGCTTGC AATCCAGAAA CTACGAAGCA AAATCCGCAA GAAGGTAGAT
AGAAAAGCCA GCAAAGGAAG GAAACTTCGG TTCCATGTCC TTAGCAAGCT CCTGAGTTTC
ATGGCACCTA TTGACCACAC CGCAATGAGT GATGATGCCA GGACGGAGTT GTTTCGATCT
CTTTTCGGCC AGCTCAACCC TCCTGATGCA GACCGTGGGA AGTGA

The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.

CloneID OMu69636
Clone ID Related Accession (Same CDS sequence) XM_011249153.2
Accession Version XM_011249153.2 Latest version! Documents for ORF clone product in dufault vector
Sequence Information ORF Nucleotide Sequence (Length: 1455bp)
Protein sequence
SNP
Vector pcDNA3.1+/C-(K)DYK or customized vector User Manual
Clone information Clone Map MSDS
Tag on pcDNA3.1+/C-(K)DYK C terminal DYKDDDDK tags
ORF Insert Method CloneEZ® Seamless cloning technology
Insert Structure linear
Update Date 2016-06-22
Organism Mus musculus(House mouse)
Product protein AATF isoform X2
Comment MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_000077.6) annotated using gene prediction method: Gnomon, supported by mRNA and EST evidence. Also see: Documentation of NCBI's Annotation Process On Jun 22, 2016 this sequence version replaced XM_011249153.1. ##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Version :: Mus musculus Annotation Release 106 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 7.1 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END##

1
61
121
181
241
301
361
421
481
541
601
661
721
781
841
901
961
1021
1081
1141
1201
1261
1321
1381
1441
ATGGCGGCGC CGCAGCCCTT GGCTCTGCAG CTGGAACAGT TGCTGAATCC GAGACCGCGT 
GAGGCGGATC CTGAGGCCGA CCCGGAGGAG GCCACTAGAG CCAGAGTGAT TGACAGGTTT
GATGAAGGGG AAGAGGAGAA AGATGATCTG GCAGTGAGTA GCATTAGAAA GTTGGCACCA
GTCTCCCTCT TGGACACCGA CAAAAGGTAT TCTGGCAAGA CCACTTCTAG GAAAGCTTGG
AAAGAAGACC ATTGGGAGCA GGCTCTGCCA AGTTCATCTG ATAACGAAGC ATCTGATGAG
GGAGGATCTG AAGATGGGGA TTCAGAGGGC CTGGGCCTGG AGGAGATCTC AGAAGATGTT
GACGAAGACT TAGAAGACAA CAAAATATCT GATGAGGGAG GATCTGAAGA TGGGGATTCA
GAGGGCCTGG GCCTGGAAGA GTTCTCAGAA GATGTTGAGG AGGACTTAGA AGGTGAGGAT
GAGGAAGACA GAGAAGAAGA CAGGAACAGT GAAGATGATG GTGTGGTGGC AGCCTTCTCC
AGTGTCAAAG TTTCTGAGGA AGTGGAAAAA GGAAGAGCTG TGAAGAATCA GATAGCATTG
TGGGACCAGC TCTTGGAAGG AAGGATCAAG CTACAAAAAG CTCTCTTGAC TACCAATCAG
TTGCCTCAAC CAGATGTTTT CCCTGTCTTC AAGGACAAAG GTGGCCCAGA ATTTGCCAGT
GCTCTGAAAA ATAGTCACAA AGCACTTAAA GCCTTGTTAA GGTCATTGGT GGATCTTCAG
GAAGAGTTGC TTTTCCAGTA CCCAGACACG AGACATATAG TAAATGGGGC GAAACCCAAT
ACAGAGAGTG AGGAGATTTC CAGTGAAGAT GATGAGCTAG TGGGAGAGAA GAAGAAACAA
CGAAAGGCCC CACCCAAGAG GAAGCTAGAG ATGGAGGACT ATCCCAGCTT CATGGCAAAG
CGCTTTGCTG ACTTCACCAT CTATAGGAAT CACACACTAC AGAAATGGCA TGATAAAACC
AAGCTTGCTT CTGGAAAACT GGGCAAGGGT TTTGGTGCCT TCGAACGCTC GATCTTGACT
CAGATCGATC ATATCATGAT GGACAAAGAA AGATTGCTTC GGAGGACACA GACCAAGCGC
TCTGCCTACC GAGTTCTTGG CAAACCGGAG CCAGTCCCTG AGCCTGTTGC AGAGACCTTG
CCAGGAGAAC CAGAGACGCT TCCTCAGGGC CCTGCCAATG CCCACCTGAG GGACTTGGAT
GAGGAGATAT TTGATGATGA TGACTTTTAC CACCAGAGCA AGAGTCCATC ATACCAAGGG
AGTCATGTCA GCAGACAGAC AGAGCAGGAA CCTGAGAGAC CACATCCTCA GTTGCAAGAA
CGGAGCAGAG CAAACTGGAA ATACTGCAAG GCTATATATT TTCAAAGCCC TCCCCCAGTG
ATCTACTTCC TCTAG

The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.

RefSeq XP_011247455.1
CDS184..1638
Misc Feature(1)745..1200
Translation

Target ORF information:

RefSeq Version XM_011249153.2
Organism Mus musculus(House mouse)
Definition Mus musculus apoptosis antagonizing transcription factor (Aatf), transcript variant X4, mRNA.

Target ORF information:

Epitope DYKDDDDK
Bacterial selection AMPR
Mammalian selection NeoR
Vector pcDNA3.1+/C-(K)DYK
XM_011249153.2

ORF Insert Sequence:

1
61
121
181
241
301
361
421
481
541
601
661
721
781
841
901
961
1021
1081
1141
1201
1261
1321
1381
1441
ATGGCGGCGC CGCAGCCCTT GGCTCTGCAG CTGGAACAGT TGCTGAATCC GAGACCGCGT 
GAGGCGGATC CTGAGGCCGA CCCGGAGGAG GCCACTAGAG CCAGAGTGAT TGACAGGTTT
GATGAAGGGG AAGAGGAGAA AGATGATCTG GCAGTGAGTA GCATTAGAAA GTTGGCACCA
GTCTCCCTCT TGGACACCGA CAAAAGGTAT TCTGGCAAGA CCACTTCTAG GAAAGCTTGG
AAAGAAGACC ATTGGGAGCA GGCTCTGCCA AGTTCATCTG ATAACGAAGC ATCTGATGAG
GGAGGATCTG AAGATGGGGA TTCAGAGGGC CTGGGCCTGG AGGAGATCTC AGAAGATGTT
GACGAAGACT TAGAAGACAA CAAAATATCT GATGAGGGAG GATCTGAAGA TGGGGATTCA
GAGGGCCTGG GCCTGGAAGA GTTCTCAGAA GATGTTGAGG AGGACTTAGA AGGTGAGGAT
GAGGAAGACA GAGAAGAAGA CAGGAACAGT GAAGATGATG GTGTGGTGGC AGCCTTCTCC
AGTGTCAAAG TTTCTGAGGA AGTGGAAAAA GGAAGAGCTG TGAAGAATCA GATAGCATTG
TGGGACCAGC TCTTGGAAGG AAGGATCAAG CTACAAAAAG CTCTCTTGAC TACCAATCAG
TTGCCTCAAC CAGATGTTTT CCCTGTCTTC AAGGACAAAG GTGGCCCAGA ATTTGCCAGT
GCTCTGAAAA ATAGTCACAA AGCACTTAAA GCCTTGTTAA GGTCATTGGT GGATCTTCAG
GAAGAGTTGC TTTTCCAGTA CCCAGACACG AGACATATAG TAAATGGGGC GAAACCCAAT
ACAGAGAGTG AGGAGATTTC CAGTGAAGAT GATGAGCTAG TGGGAGAGAA GAAGAAACAA
CGAAAGGCCC CACCCAAGAG GAAGCTAGAG ATGGAGGACT ATCCCAGCTT CATGGCAAAG
CGCTTTGCTG ACTTCACCAT CTATAGGAAT CACACACTAC AGAAATGGCA TGATAAAACC
AAGCTTGCTT CTGGAAAACT GGGCAAGGGT TTTGGTGCCT TCGAACGCTC GATCTTGACT
CAGATCGATC ATATCATGAT GGACAAAGAA AGATTGCTTC GGAGGACACA GACCAAGCGC
TCTGCCTACC GAGTTCTTGG CAAACCGGAG CCAGTCCCTG AGCCTGTTGC AGAGACCTTG
CCAGGAGAAC CAGAGACGCT TCCTCAGGGC CCTGCCAATG CCCACCTGAG GGACTTGGAT
GAGGAGATAT TTGATGATGA TGACTTTTAC CACCAGAGCA AGAGTCCATC ATACCAAGGG
AGTCATGTCA GCAGACAGAC AGAGCAGGAA CCTGAGAGAC CACATCCTCA GTTGCAAGAA
CGGAGCAGAG CAAACTGGAA ATACTGCAAG GCTATATATT TTCAAAGCCC TCCCCCAGTG
ATCTACTTCC TCTAG

The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.

book

Nucleolar AATF regulates c-Jun-mediated apoptosis.
Molecular biology of the cell23(21)4323-32(2012 Nov)
Ferraris SE,Isoniemi K,Torvaldson E,Anckar J,Westermarck J,Eriksson JE


book

AATF mediates an antiapoptotic effect of the unfolded protein response through transcriptional regulation of AKT1.
Cell death and differentiation17(5)774-86(2010 May)
Ishigaki S,Fonseca SG,Oslowski CM,Jurczyk A,Shearstone JR,Zhu LJ,Permutt MA,Greiner DL,Bortell R,Urano F


book

Resolution of cell fate decisions revealed by single-cell gene expression analysis from zygote to blastocyst.
Developmental cell18(4)675-85(2010 Apr)
Guo G,Huss M,Tong GQ,Wang C,Li Sun L,Clarke ND,Robson P


book

A systems approach reveals that the myogenesis genome network is regulated by the transcriptional repressor RP58.
Developmental cell17(6)836-48(2009 Dec)
Yokoyama S,Ito Y,Ueno-Kudoh H,Shimizu H,Uchibe K,Albini S,Mitsuoka K,Miyaki S,Kiso M,Nagai A,Hikata T,Osada T,Fukuda N,Yamashita S,Harada D,Mezzano V,Kasai M,Puri PL,Hayashizaki Y,Okado H,Hashimoto M,Asahara H


book

NRAGE associates with the anti-apoptotic factor Che-1 and regulates its degradation to induce cell death.
Journal of cell science120(Pt 11)1852-8(2007 Jun)
Di Certo MG,Corbi N,Bruno T,Iezzi S,De Nicola F,Desantis A,Ciotti MT,Mattei E,Floridi A,Fanciulli M,Passananti C


 
*
*
*
*