Gene Symbol | Ruvbl1 |
Entrez Gene ID | 56505 |
Full Name | RuvB-like protein 1 |
Synonyms | 2510009G06Rik,Pontin52,Tip49a |
General protein information |
|
Gene Type | protein-coding |
Organism | Mus musculus(house mouse) |
Genome |
ORF » Species Summary » Mus musculus » Ruvbl1 cDNA ORF clone
Gene Symbol | Ruvbl1 |
Entrez Gene ID | 56505 |
Full Name | RuvB-like protein 1 |
Synonyms | 2510009G06Rik,Pontin52,Tip49a |
General protein information |
|
Gene Type | protein-coding |
Organism | Mus musculus(house mouse) |
Genome |
mRNA | Protein | Name |
---|---|---|
NM_019685.2 | NP_062659.1 | ruvB-like 1 |
NM_019685.3 | NP_062659.1 | ruvB-like 1 |
Pan troglodytes (chimpanzee) | RUVBL1 | NP_001233458.1 |
RUVBL1 | XP_002798758.1 | |
Gallus gallus (chicken) | RUVBL1 | NP_001006138.1 |
Drosophila melanogaster (fruit fly) | pont | NP_652608.1 |
Caenorhabditis elegans (roundworm) | ruvb-1 | NP_505567.2 |
Saccharomyces cerevisiae (baker's yeast) | RVB1 | NP_010476.1 |
Eremothecium gossypii | AGOS_AGL119C | NP_986548.1 |
Homo sapiens (human) | RUVBL1 | NP_003698.1 |
Mus musculus (house mouse) | Ruvbl1 | NP_062659.1 |
Rattus norvegicus (Norway rat) | Ruvbl1 | NP_671706.1 |
Magnaporthe oryzae (rice blast fungus) | MGG_03958 | XP_003719906.1 |
Oryza sativa (rice) | Os01g0837500 | NP_001044738.1 |
Xenopus tropicalis (tropical clawed frog) | ruvbl1 | XP_002933113.1 |
Canis lupus familiaris (dog) | RUVBL1 | XP_848712.1 |
Bos taurus (cattle) | RUVBL1 | NP_001094546.1 |
Danio rerio (zebrafish) | ruvbl1 | NP_776196.2 |
Kluyveromyces lactis | KLLA0D18502g | XP_453880.1 |
Schizosaccharomyces pombe (fission yeast) | rvb1 | NP_594783.1 |
Neurospora crassa | NCU03482 | XP_955769.1 |
Arabidopsis thaliana (thale cress) | RIN1 | NP_197625.1 |
Axonemal dynein assembly requires the R2TP complex component Pontin.
Li Y, Zhao L, Yuan S, Zhang J, Sun Z
Development (Cambridge, England)144(24)4684-4693(2017 Dec)
Recruitment of Pontin/Reptin by E2f1 amplifies E2f transcriptional response during cancer progression.
Tarangelo A, Lo N, Teng R, Kim E, Le L, Watson D, Furth EE, Raman P, Ehmer U, Viatour P
Nature communications610028(2015 Dec)
A Novel Interaction of Ecdysoneless (ECD) Protein with R2TP Complex Component RUVBL1 Is Required for the Functional Role of ECD in Cell Cycle Progression.
Mir RA, Bele A, Mirza S, Srivastava S, Olou AA, Ammons SA, Kim JH, Gurumurthy CB, Qiu F, Band H, Band V
Molecular and cellular biology36(6)886-99(2015 Dec)
A human interactome in three quantitative dimensions organized by stoichiometries and abundances.
Hein MY, Hubner NC, Poser I, Cox J, Nagaraj N, Toyoda Y, Gak IA, Weisswange I, Mansfeld J, Buchholz F, Hyman AA, Mann M
Cell163(3)712-23(2015 Oct)
GeneRIFs: Gene References Into Functions What's a GeneRIF?
In mouse testis, Pontin is essential for the stabilization of axonemal dynein intermediate chain 1 (DNAI1) and DNAI2, the first appreciated step in axonemal dynein arm assembly.
Title: Axonemal dynein assembly requires the R2TP complex component Pontin.
accumulating E2f1 progressively recruits a Pontin/Reptin complex to open the chromatin conformation at E2f target genes and amplifies the E2f transcriptional response.
Title: Recruitment of Pontin/Reptin by E2f1 amplifies E2f transcriptional response during cancer progression.
Pontin functions as an essential coactivator for Oct4-dependent large intergenic noncoding RNA expression in mouse embryonic stem cells.
Title: Pontin functions as an essential coactivator for Oct4-dependent lincRNA expression in mouse embryonic stem cells.
Loss of Ruvbl1 gene is associated with bone marrow failure.
Title: Pontin is essential for murine hematopoietic stem cell survival.
The following Ruvbl1 gene cDNA ORF clone sequences were retrieved from the NCBI Reference Sequence Database (RefSeq). These sequences represent the protein coding region of the Ruvbl1 cDNA ORF which is encoded by the open reading frame (ORF) sequence. ORF sequences can be delivered in our standard vector, pcDNA3.1+/C-(K)DYK or the vector of your choice as an expression/transfection-ready ORF clone. Not the clone you want? Click here to find your clone.
CloneID | OMu11614 | |
Clone ID Related Accession (Same CDS sequence) | NM_019685.2 , NM_019685.3 | |
Accession Version | NM_019685.2 | Documents for ORF clone product in default vector |
Sequence Information | ORF Nucleotide Sequence (Length: 1371bp) Protein sequence SNP |
|
Vector | pcDNA3.1-C-(k)DYK or customized vector | User Manual |
Clone information | Clone Map | MSDS |
Tag on pcDNA3.1+/C-(K)DYK | C terminal DYKDDDDK tags | |
ORF Insert Method | CloneEZ™ Seamless cloning technology | |
Insert Structure | linear | |
Update Date | 2015-02-14 | |
Organism | Mus musculus(House mouse) | |
Product | ruvB-like 1 | |
Comment |
1 | ATGAAGATTG AGGAGGTGAA GAGCACCACG AAGACGCAGC GCATCGCCTC CCACAGCCAC |
The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.
RefSeq | NP_062659.1 |
Translation |
Target ORF information:
Target ORF information:
|
NM_019685.2 |
1 | ATGAAGATTG AGGAGGTGAA GAGCACCACG AAGACGCAGC GCATCGCCTC CCACAGCCAC |
The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.
CloneID | OMu11614 | |
Clone ID Related Accession (Same CDS sequence) | NM_019685.2 , NM_019685.3 | |
Accession Version | NM_019685.3 Latest version! | Documents for ORF clone product in default vector |
Sequence Information | ORF Nucleotide Sequence (Length: 1371bp) Protein sequence SNP |
|
Vector | pcDNA3.1-C-(k)DYK or customized vector | User Manual |
Clone information | Clone Map | MSDS |
Tag on pcDNA3.1+/C-(K)DYK | C terminal DYKDDDDK tags | |
ORF Insert Method | CloneEZ™ Seamless cloning technology | |
Insert Structure | linear | |
Update Date | 2019-06-07 | |
Organism | Mus musculus(house mouse) | |
Product | ruvB-like 1 | |
Comment | Comment: VALIDATED REFSEQ: This record has undergone validation or preliminary review. The reference sequence was derived from AC153694.1, AK132783.1 and AF100694.2. On Dec 30, 2016 this sequence version replaced NM_019685.2. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Gene record to access additional publications. ##Evidence-Data-START## Transcript exon combination :: BC004718.1, AK146374.1 [ECO:0000332] RNAseq introns :: single sample supports all introns SAMN00849374, SAMN00849375 [ECO:0000348] ##Evidence-Data-END## COMPLETENESS: complete on the 3' end. |
1 | ATGAAGATTG AGGAGGTGAA GAGCACCACG AAGACGCAGC GCATCGCCTC CCACAGCCAC |
The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.
RefSeq | NP_062659.1 |
CDS | 120..1490 |
Translation |
Target ORF information:
Target ORF information:
|
NM_019685.3 |
1 | ATGAAGATTG AGGAGGTGAA GAGCACCACG AAGACGCAGC GCATCGCCTC CCACAGCCAC |
The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.
Axonemal dynein assembly requires the R2TP complex component Pontin. |
Recruitment of Pontin/Reptin by E2f1 amplifies E2f transcriptional response during cancer progression. |
A Novel Interaction of Ecdysoneless (ECD) Protein with R2TP Complex Component RUVBL1 Is Required for the Functional Role of ECD in Cell Cycle Progression. |
A human interactome in three quantitative dimensions organized by stoichiometries and abundances. |