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Pard6a cDNA ORF clone, Mus musculus(house mouse)

Summary

Gene Symbol Pard6a
Entrez Gene ID 56513
Full Name par-6 family cell polarity regulator alpha
Synonyms 0710008C04Rik,2610010A15Rik,PAR-6A,PAR6alpha,Par-6,Par6,Par6c,TAX40,Tip-40
General protein information
Preferred Names

par-6 family cell polarity regulator alpha

Names

partitioning defective 6 homolog alpha
PAR-6 alpha
Tax interaction protein 40
par-6 (partitioning defective 6,) homolog alpha
Gene Type protein-coding
Organism Mus musculus(house mouse)
Genome

8

8|8 D3

Reference Sequences (RefSeq)

mRNA and Protein(s)

mRNA Protein Name
NM_001047436.2 NP_001040901.1 partitioning defective 6 homolog alpha isoform 3
NM_019695.3 NP_062669.2 partitioning defective 6 homolog alpha isoform 1
NM_001047435.2 NP_001040900.1 partitioning defective 6 homolog alpha isoform 2
NM_001286345.1 NP_001273274.1 partitioning defective 6 homolog alpha isoform 5
NM_001286344.1 NP_001273273.1 partitioning defective 6 homolog alpha isoform 4

Pathways from BioSystems


Homologies


Canis lupus familiaris (dog) PARD6A XP_546876.5
Mus musculus (house mouse) Pard6a NP_062669.2
Gallus gallus (chicken) PARD6A XP_004944104.1
Danio rerio (zebrafish) pard6a NP_001093521.2
PARD6A XP_001092684.1
Bos taurus (cattle) PARD6A NP_001039739.1
Homo sapiens (human) PARD6A NP_058644.1
Pan troglodytes (chimpanzee) PARD6A XP_511037.2
Rattus norvegicus (Norway rat) Pard6a NP_001003653.1

Gene Ontology


Bibliography

Related articles in PubMed

FRMD4A-cytohesin signaling modulates the cellular release of tau.
Yan X, Nyk?nen NP, Brunello CA, Haapasalo A, Hiltunen M, Uronen RL, Huttunen HJ
Journal of cell science129(10)2003-15(2016 05)

Zeb1 controls neuron differentiation and germinal zone exit by a mesenchymal-epithelial-like transition.
Singh S, Howell D, Trivedi N, Kessler K, Ong T, Rosmaninho P, Raposo AA, Robinson G, Roussel MF, Castro DS, Solecki DJ
eLife5(2016 05)

Antagonistic functions of Dishevelleds regulate Frizzled3 endocytosis via filopodia tips in Wnt-mediated growth cone guidance.
Onishi K, Shafer B, Lo C, Tissir F, Goffinet AM, Zou Y
The Journal of neuroscience : the official journal of the Society for Neuroscience33(49)19071-85(2013 Dec)

Loss of aPKC? in differentiated neurons disrupts the polarity complex but does not induce obvious neuronal loss or disorientation in mouse brains.
Yamanaka T, Tosaki A, Kurosawa M, Akimoto K, Hirose T, Ohno S, Hattori N, Nukina N
PloS one8(12)e84036(2013)

GeneRIFs: Gene References Into Functions What's a GeneRIF?

Our results provide the first in vivo characterization of RalA function in the mammalian brain and highlight a novel
Title: RalA promotes a direct exocyst-Par6 interaction to regulate polarity in neuronal development.

Lgl1 forms two distinct complexes in vivo, Lgl1-NMIIA and Lgl1-Par6alpha-aPKCzeta, and that the formation of these complexes is affected by the phosphorylation state of Lgl1.
Title: The tumor suppressor Lgl1 forms discrete complexes with NMII-A and Par6?-aPKC? that are affected by Lgl1 phosphorylation.

The nucleus of a myoblast moves rapidly after fusion towards the central myotube nuclei which is driven by microtubules and dynein/dynactin complex, and requires Cdc42, Par6 and Par3.
Title: Nuclear movement during myotube formation is microtubule and dynein dependent and is regulated by Cdc42, Par6 and Par3.

PAR6 has a role in forming primordial follicles in mouse ovary
Title: PAR6, a potential marker for the germ cells selected to form primordial follicles in mouse ovary.

the TGFbeta-Par6 polarity pathway has a role in breast cancer progression
Title: A role for the TGFbeta-Par6 polarity pathway in breast cancer progression.

The following Pard6a gene cDNA ORF clone sequences were retrieved from the NCBI Reference Sequence Database (RefSeq). These sequences represent the protein coding region of the Pard6a cDNA ORF which is encoded by the open reading frame (ORF) sequence. ORF sequences can be delivered in our standard vector, pcDNA3.1+/C-(K)DYK or the vector of your choice as an expression/transfection-ready ORF clone. Not the clone you want? Click here to find your clone.

***CloneID Accession No. Definition **Vector *Turnaround time Price (USD) Select
OMu19901 NM_001286344.1
Latest version!		 Mus musculus par-6 family cell polarity regulator alpha (Pard6a), transcript variant 4, mRNA. pcDNA3.1+/C-(K)DYK or customized vector 5-7 $69.30
$99.00
OMu19753 NM_019695.3
Latest version!		 Mus musculus par-6 family cell polarity regulator alpha (Pard6a), transcript variant 1, mRNA. pcDNA3.1+/C-(K)DYK or customized vector 7-9 $223.30
$319.00
OMu19843 NM_001047436.2
Latest version!		 Mus musculus par-6 family cell polarity regulator alpha (Pard6a), transcript variant 3, mRNA. pcDNA3.1+/C-(K)DYK or customized vector 7-9 $188.30
$269.00
OMu19878 NM_001286345.1
Latest version!		 Mus musculus par-6 family cell polarity regulator alpha (Pard6a), transcript variant 5, mRNA. pcDNA3.1+/C-(K)DYK or customized vector 7-9 $139.30
$199.00
OMu19773 NM_001047435.2
Latest version!		 Mus musculus par-6 family cell polarity regulator alpha (Pard6a), transcript variant 2, mRNA. pcDNA3.1+/C-(K)DYK or customized vector 5-7 $223.30
$319.00

ORF Online Only Promotion

Next-day Shipping ORF Clones ( in default vector with tag)
1 Clone 30% OFF
2-4 Clone 40% OFF
5 or more Clone 50% OFF
All Other ORF Clones
30% OFF

*Business Day

** You may select a custom vector to replace pcDNA3.1+/C-(K)DYK after clone is added to cart.

** GenScript guarantees 100% sequence accuracy of all synthetic DNA constructs we deliver, but we do not guarantee protein expression in your experimental system. Protein expression is influenced by many factors that may vary between experiments or laboratories. In addition, please pay attention to the signal peptide, propeptide and transit peptide in target ORF, which may affect the choice of vector (N/C terminal tag vector).

***One clone ID might be correlated to multiple accession numbers, which share the same CDS sequence.

Reference Sequences (Refseq)


CloneID OMu19901
Clone ID Related Accession (Same CDS sequence) NM_001286344.1
Accession Version NM_001286344.1 Latest version! Documents for ORF clone product in default vector
Sequence Information ORF Nucleotide Sequence (Length: 513bp)
Protein sequence
SNP
Vector pcDNA3.1+/C-(K)DYK or customized vector User Manual
Clone information Clone Map MSDS
Tag on pcDNA3.1+/C-(K)DYK C terminal DYKDDDDK tags
ORF Insert Method CloneEZ™ Seamless cloning technology
Insert Structure linear
Update Date 2019-09-30
Organism Mus musculus(house mouse)
Product partitioning defective 6 homolog alpha isoform 4
Comment Comment: VALIDATED REFSEQ: This record has undergone validation or preliminary review. The reference sequence was derived from BY099545.1, CK618363.1, AK158848.1 and BF466814.1. Transcript Variant: This variant (4) differs in the 5' UTR, lacks a portion of the 5' coding region, and initiates translation at a downstream start codon. This encodes a shorter protein (isoform 4), compared to isoform 1. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Gene record to access additional publications. ##Evidence-Data-START## Transcript exon combination :: BY099545.1, BI409102.1 [ECO:0000332] RNAseq introns :: single sample supports all introns SAMN00849374, SAMN00849375 [ECO:0000348] ##Evidence-Data-END## COMPLETENESS: complete on the 3' end. 

1
61
121
181
241
301
361
421
481
ATGAGTGTTC GCGTGGCTCC CCAGGGCCTG GAGCGGGTTC CAGGTATCTT CATCTCCCGC 
CTGGTACGTG GGGGCCTGGC TGAGAGTACA GGGCTGCTGG CGGTCAGTGA TGAGATCCTT 
GAGGTCAACG GCATTGAGGT GGCCGGGAAG ACCTTGGACC AAGTGACGGA CATGATGGTC 
GCCAACAGCC ACAACCTCAT CGTCACTGTC AAGCCTGCCA ACCAGCGTAA TAATGTGGTA 
CGGGGGGCAT CTGGGCGTCT GACAGGGCCT TCCTCTGTAG GGCCTGGGCC TACTGATCCT 
GACAGTGACG ATGACAGCAG TGACCTGGTC ATTGAGAATC GCCACCCTCC CTGTTCTAAT 
GGGCTGTCTC AGGGGCCCCT GTGCTGGGAC CTGCAACCTG GCTGCCTACT TCCTGGTGCT 
GGCAGCTCTC TGCCCTCCTT GGATAGCAGA GAGCAAGCCA ATTCTGGCTG GGGGAATGGC 
ATGCGAGGTG ATGTTAGCGG ATTCAGCCTC TGA

The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.

RefSeq NP_001273273.1
CDS605..1117
Translation

Target ORF information:

RefSeq Version NM_001286344.1
Organism Mus musculus(house mouse)
Definition Mus musculus par-6 family cell polarity regulator alpha (Pard6a), transcript variant 4, mRNA.

Target ORF information:

Epitope DYKDDDDK
Bacterial selection AMPR
Mammalian selection NeoR
Vector pcDNA3.1+/C-(K)DYK
 NM_001286344.1

ORF Insert Sequence:

1
61
121
181
241
301
361
421
481
ATGAGTGTTC GCGTGGCTCC CCAGGGCCTG GAGCGGGTTC CAGGTATCTT CATCTCCCGC 
CTGGTACGTG GGGGCCTGGC TGAGAGTACA GGGCTGCTGG CGGTCAGTGA TGAGATCCTT 
GAGGTCAACG GCATTGAGGT GGCCGGGAAG ACCTTGGACC AAGTGACGGA CATGATGGTC 
GCCAACAGCC ACAACCTCAT CGTCACTGTC AAGCCTGCCA ACCAGCGTAA TAATGTGGTA 
CGGGGGGCAT CTGGGCGTCT GACAGGGCCT TCCTCTGTAG GGCCTGGGCC TACTGATCCT 
GACAGTGACG ATGACAGCAG TGACCTGGTC ATTGAGAATC GCCACCCTCC CTGTTCTAAT 
GGGCTGTCTC AGGGGCCCCT GTGCTGGGAC CTGCAACCTG GCTGCCTACT TCCTGGTGCT 
GGCAGCTCTC TGCCCTCCTT GGATAGCAGA GAGCAAGCCA ATTCTGGCTG GGGGAATGGC 
ATGCGAGGTG ATGTTAGCGG ATTCAGCCTC TGA

The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.

CloneID OMu19753
Clone ID Related Accession (Same CDS sequence) NM_019695.3
Accession Version NM_019695.3 Latest version! Documents for ORF clone product in default vector
Sequence Information ORF Nucleotide Sequence (Length: 1041bp)
Protein sequence
SNP
Vector pcDNA3.1+/C-(K)DYK or customized vector User Manual
Clone information Clone Map MSDS
Tag on pcDNA3.1+/C-(K)DYK C terminal DYKDDDDK tags
ORF Insert Method CloneEZ™ Seamless cloning technology
Insert Structure linear
Update Date 2019-12-27
Organism Mus musculus(house mouse)
Product partitioning defective 6 homolog alpha isoform 1
Comment Comment: VALIDATED REFSEQ: This record has undergone validation or preliminary review. The reference sequence was derived from AC152826.2, AK158848.1, CX206739.1 and BF466814.1. On Nov 2, 2013 this sequence version replaced NM_019695.2. Transcript Variant: This variant (1) encodes the longest protein (isoform 1). Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Gene record to access additional publications. ##Evidence-Data-START## Transcript exon combination :: AF070970.1, BG806503.1 [ECO:0000332] RNAseq introns :: single sample supports all introns SAMN00849374, SAMN00849375 [ECO:0000348] ##Evidence-Data-END## COMPLETENESS: complete on the 3' end. 

1
61
121
181
241
301
361
421
481
541
601
661
721
781
841
901
961
1021
ATGGCCAGGC CGCAGAGGAC TCCGGCGCGC AGTCCCGATA GCATCGTCGA GGTGAAGAGC 
AAATTTGACG CCGAGTTCCG ACGCTTTGCA CTACCCCGCA CTTCGGTGAG AGGCTTTCAG 
GAGTTCTCGC GATTGCTGTG TGTGGTACAC CAGATCCCTG GCCTGGACGT CCTGCTTGGC 
TATACGGATG CTCACGGTGA CTTGCTGCCC CTCACCAACG ATGACAGTTT GCACCGGGCC 
CTGGCCAGCG GGCCCCCACC TCTGCGCCTC TTGGTTCAGA AACGGGCAGA AGGTGACTCG 
AGTGGCCTGG CTTTTGCCTC CAACTCTCTA CAAAGGCGCA AGAAAGGGCT CCTGCTACGA 
CCAGTGGCAC CTCTGCGCAC CAGGCCACCC TTGTTAATCA GCTTGCCCCA AGATTTCCGC 
CAGGTGTCTT CAGTTATAGA TGTGGACCTA CTACCTGAGA CCCACCGACG AGTGAGGCTG 
CACAAACATG GTTCAGACCG TCCCCTGGGC TTCTACATTC GAGATGGCAT GAGTGTTCGC 
GTGGCTCCCC AGGGCCTGGA GCGGGTTCCA GGTATCTTCA TCTCCCGCCT GGTACGTGGG 
GGCCTGGCTG AGAGTACAGG GCTGCTGGCG GTCAGTGATG AGATCCTTGA GGTCAACGGC 
ATTGAGGTGG CCGGGAAGAC CTTGGACCAA GTGACGGACA TGATGGTCGC CAACAGCCAC 
AACCTCATCG TCACTGTCAA GCCTGCCAAC CAGCGTAATA ATGTGGTACG GGGGGCATCT 
GGGCGTCTGA CAGGGCCTTC CTCTGTAGGG CCTGGGCCTA CTGATCCTGA CAGTGACGAT 
GACAGCAGTG ACCTGGTCAT TGAGAATCGC CACCCTCCCT GTTCTAATGG GCTGTCTCAG 
GGGCCCCTGT GCTGGGACCT GCAACCTGGC TGCCTACTTC CTGGTGCTGG CAGCTCTCTG 
CCCTCCTTGG ATAGCAGAGA GCAAGCCAAT TCTGGCTGGG GGAATGGCAT GCGAGGTGAT 
GTTAGCGGAT TCAGCCTCTG A

The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.

RefSeq NP_062669.2
CDS95..1135
Translation

Target ORF information:

RefSeq Version NM_019695.3
Organism Mus musculus(house mouse)
Definition Mus musculus par-6 family cell polarity regulator alpha (Pard6a), transcript variant 1, mRNA.

Target ORF information:

Epitope DYKDDDDK
Bacterial selection AMPR
Mammalian selection NeoR
Vector pcDNA3.1+/C-(K)DYK
 NM_019695.3

ORF Insert Sequence:

1
61
121
181
241
301
361
421
481
541
601
661
721
781
841
901
961
1021
ATGGCCAGGC CGCAGAGGAC TCCGGCGCGC AGTCCCGATA GCATCGTCGA GGTGAAGAGC 
AAATTTGACG CCGAGTTCCG ACGCTTTGCA CTACCCCGCA CTTCGGTGAG AGGCTTTCAG 
GAGTTCTCGC GATTGCTGTG TGTGGTACAC CAGATCCCTG GCCTGGACGT CCTGCTTGGC 
TATACGGATG CTCACGGTGA CTTGCTGCCC CTCACCAACG ATGACAGTTT GCACCGGGCC 
CTGGCCAGCG GGCCCCCACC TCTGCGCCTC TTGGTTCAGA AACGGGCAGA AGGTGACTCG 
AGTGGCCTGG CTTTTGCCTC CAACTCTCTA CAAAGGCGCA AGAAAGGGCT CCTGCTACGA 
CCAGTGGCAC CTCTGCGCAC CAGGCCACCC TTGTTAATCA GCTTGCCCCA AGATTTCCGC 
CAGGTGTCTT CAGTTATAGA TGTGGACCTA CTACCTGAGA CCCACCGACG AGTGAGGCTG 
CACAAACATG GTTCAGACCG TCCCCTGGGC TTCTACATTC GAGATGGCAT GAGTGTTCGC 
GTGGCTCCCC AGGGCCTGGA GCGGGTTCCA GGTATCTTCA TCTCCCGCCT GGTACGTGGG 
GGCCTGGCTG AGAGTACAGG GCTGCTGGCG GTCAGTGATG AGATCCTTGA GGTCAACGGC 
ATTGAGGTGG CCGGGAAGAC CTTGGACCAA GTGACGGACA TGATGGTCGC CAACAGCCAC 
AACCTCATCG TCACTGTCAA GCCTGCCAAC CAGCGTAATA ATGTGGTACG GGGGGCATCT 
GGGCGTCTGA CAGGGCCTTC CTCTGTAGGG CCTGGGCCTA CTGATCCTGA CAGTGACGAT 
GACAGCAGTG ACCTGGTCAT TGAGAATCGC CACCCTCCCT GTTCTAATGG GCTGTCTCAG 
GGGCCCCTGT GCTGGGACCT GCAACCTGGC TGCCTACTTC CTGGTGCTGG CAGCTCTCTG 
CCCTCCTTGG ATAGCAGAGA GCAAGCCAAT TCTGGCTGGG GGAATGGCAT GCGAGGTGAT 
GTTAGCGGAT TCAGCCTCTG A

The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.

CloneID OMu19843
Clone ID Related Accession (Same CDS sequence) NM_001047436.2
Accession Version NM_001047436.2 Latest version! Documents for ORF clone product in default vector
Sequence Information ORF Nucleotide Sequence (Length: 993bp)
Protein sequence
SNP
Vector pcDNA3.1+/C-(K)DYK or customized vector User Manual
Clone information Clone Map MSDS
Tag on pcDNA3.1+/C-(K)DYK C terminal DYKDDDDK tags
ORF Insert Method CloneEZ™ Seamless cloning technology
Insert Structure linear
Update Date 2019-09-30
Organism Mus musculus(house mouse)
Product partitioning defective 6 homolog alpha isoform 3
Comment Comment: VALIDATED REFSEQ: This record has undergone validation or preliminary review. The reference sequence was derived from AC152826.2, CX220562.1, AK158848.1 and BF466814.1. On Nov 2, 2013 this sequence version replaced NM_001047436.1. Transcript Variant: This variant (3) differs in the 5' UTR, lacks a portion of the 5' coding region, and initiates translation at an alternate start codon. This encodes a shorter protein (isoform 3), compared to isoform 1. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Gene record to access additional publications. ##Evidence-Data-START## Transcript exon combination :: BU939458.1, CX206739.1 [ECO:0000332] RNAseq introns :: single sample supports all introns SAMN00849374, SAMN00849375 [ECO:0000348] ##Evidence-Data-END## COMPLETENESS: complete on the 3' end. 

1
61
121
181
241
301
361
421
481
541
601
661
721
781
841
901
961
ATGAGAGCGA TCCAGTTTGA CGCCGAGTTC CGACGCTTTG CACTACCCCG CACTTCGGTG 
AGAGGCTTTC AGGAGTTCTC GCGATTGCTG TGTGTGGTAC ACCAGATCCC TGGCCTGGAC 
GTCCTGCTTG GCTATACGGA TGCTCACGGT GACTTGCTGC CCCTCACCAA CGATGACAGT 
TTGCACCGGG CCCTGGCCAG CGGGCCCCCA CCTCTGCGCC TCTTGGTTCA GAAACGGGCA 
GAAGGTGACT CGAGTGGCCT GGCTTTTGCC TCCAACTCTC TACAAAGGCG CAAGAAAGGG 
CTCCTGCTAC GACCAGTGGC ACCTCTGCGC ACCAGGCCAC CCTTGTTAAT CAGCTTGCCC 
CAAGATTTCC GCCAGGTGTC TTCAGTTATA GATGTGGACC TACTACCTGA GACCCACCGA 
CGAGTGAGGC TGCACAAACA TGGTTCAGAC CGTCCCCTGG GCTTCTACAT TCGAGATGGC 
ATGAGTGTTC GCGTGGCTCC CCAGGGCCTG GAGCGGGTTC CAGGTATCTT CATCTCCCGC 
CTGGTACGTG GGGGCCTGGC TGAGAGTACA GGGCTGCTGG CGGTCAGTGA TGAGATCCTT 
GAGGTCAACG GCATTGAGGT GGCCGGGAAG ACCTTGGACC AAGTGACGGA CATGATGGTC 
GCCAACAGCC ACAACCTCAT CGTCACTGTC AAGCCTGCCA ACCAGCGTAA TAATGTGGTA 
CGGGGGGCAT CTGGGCGTCT GACAGGGCCT TCCTCTGTAG GGCCTGGGCC TACTGATCCT 
GACAGTGACG ATGACAGCAG TGACCTGGTC ATTGAGAATC GCCACCCTCC CTGTTCTAAT 
GGGCTGTCTC AGGGGCCCCT GTGCTGGGAC CTGCAACCTG GCTGCCTACT TCCTGGTGCT 
GGCAGCTCTC TGCCCTCCTT GGATAGCAGA GAGCAAGCCA ATTCTGGCTG GGGGAATGGC 
ATGCGAGGTG ATGTTAGCGG ATTCAGCCTC TGA

The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.

RefSeq NP_001040901.1
CDS156..1148
Translation

Target ORF information:

RefSeq Version NM_001047436.2
Organism Mus musculus(house mouse)
Definition Mus musculus par-6 family cell polarity regulator alpha (Pard6a), transcript variant 3, mRNA.

Target ORF information:

Epitope DYKDDDDK
Bacterial selection AMPR
Mammalian selection NeoR
Vector pcDNA3.1+/C-(K)DYK
 NM_001047436.2

ORF Insert Sequence:

1
61
121
181
241
301
361
421
481
541
601
661
721
781
841
901
961
ATGAGAGCGA TCCAGTTTGA CGCCGAGTTC CGACGCTTTG CACTACCCCG CACTTCGGTG 
AGAGGCTTTC AGGAGTTCTC GCGATTGCTG TGTGTGGTAC ACCAGATCCC TGGCCTGGAC 
GTCCTGCTTG GCTATACGGA TGCTCACGGT GACTTGCTGC CCCTCACCAA CGATGACAGT 
TTGCACCGGG CCCTGGCCAG CGGGCCCCCA CCTCTGCGCC TCTTGGTTCA GAAACGGGCA 
GAAGGTGACT CGAGTGGCCT GGCTTTTGCC TCCAACTCTC TACAAAGGCG CAAGAAAGGG 
CTCCTGCTAC GACCAGTGGC ACCTCTGCGC ACCAGGCCAC CCTTGTTAAT CAGCTTGCCC 
CAAGATTTCC GCCAGGTGTC TTCAGTTATA GATGTGGACC TACTACCTGA GACCCACCGA 
CGAGTGAGGC TGCACAAACA TGGTTCAGAC CGTCCCCTGG GCTTCTACAT TCGAGATGGC 
ATGAGTGTTC GCGTGGCTCC CCAGGGCCTG GAGCGGGTTC CAGGTATCTT CATCTCCCGC 
CTGGTACGTG GGGGCCTGGC TGAGAGTACA GGGCTGCTGG CGGTCAGTGA TGAGATCCTT 
GAGGTCAACG GCATTGAGGT GGCCGGGAAG ACCTTGGACC AAGTGACGGA CATGATGGTC 
GCCAACAGCC ACAACCTCAT CGTCACTGTC AAGCCTGCCA ACCAGCGTAA TAATGTGGTA 
CGGGGGGCAT CTGGGCGTCT GACAGGGCCT TCCTCTGTAG GGCCTGGGCC TACTGATCCT 
GACAGTGACG ATGACAGCAG TGACCTGGTC ATTGAGAATC GCCACCCTCC CTGTTCTAAT 
GGGCTGTCTC AGGGGCCCCT GTGCTGGGAC CTGCAACCTG GCTGCCTACT TCCTGGTGCT 
GGCAGCTCTC TGCCCTCCTT GGATAGCAGA GAGCAAGCCA ATTCTGGCTG GGGGAATGGC 
ATGCGAGGTG ATGTTAGCGG ATTCAGCCTC TGA

The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.

CloneID OMu19878
Clone ID Related Accession (Same CDS sequence) NM_001286345.1
Accession Version NM_001286345.1 Latest version! Documents for ORF clone product in default vector
Sequence Information ORF Nucleotide Sequence (Length: 951bp)
Protein sequence
SNP
Vector pcDNA3.1+/C-(K)DYK or customized vector User Manual
Clone information Clone Map MSDS
Tag on pcDNA3.1+/C-(K)DYK C terminal DYKDDDDK tags
ORF Insert Method CloneEZ™ Seamless cloning technology
Insert Structure linear
Update Date 2019-09-30
Organism Mus musculus(house mouse)
Product partitioning defective 6 homolog alpha isoform 5
Comment Comment: VALIDATED REFSEQ: This record has undergone validation or preliminary review. The reference sequence was derived from AC152826.2, AK158848.1, CX206739.1 and BF466814.1. Transcript Variant: This variant (5) uses an alternate in-frame splice site in the coding region, compared to variant 1. This encodes a shorter protein (isoform 4), compared to isoform 1. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Gene record to access additional publications. ##Evidence-Data-START## Transcript exon combination :: BC061114.1 [ECO:0000332] RNAseq introns :: single sample supports all introns SAMN00849374, SAMN00849375 [ECO:0000348] ##Evidence-Data-END## COMPLETENESS: complete on the 3' end. 

1
61
121
181
241
301
361
421
481
541
601
661
721
781
841
901
ATGGCCAGGC CGCAGAGGAC TCCGGCGCGC AGTCCCGATA GCATCGTCGA GGTGAAGAGC 
AAATTTGACG CCGAGTTCCG ACGCTTTGCA CTACCCCGCA CTTCGGTGAG AGGCTTTCAG 
GAGTTCTCGC GATTGCTGTG TGTGGTACAC CAGATCCCTG GCCTGGACGT CCTGCTTGGC 
TATACGGATG CTCACGCAGA AGGTGACTCG AGTGGCCTGG CTTTTGCCTC CAACTCTCTA 
CAAAGGCGCA AGAAAGGGCT CCTGCTACGA CCAGTGGCAC CTCTGCGCAC CAGGCCACCC 
TTGTTAATCA GCTTGCCCCA AGATTTCCGC CAGGTGTCTT CAGTTATAGA TGTGGACCTA 
CTACCTGAGA CCCACCGACG AGTGAGGCTG CACAAACATG GTTCAGACCG TCCCCTGGGC 
TTCTACATTC GAGATGGCAT GAGTGTTCGC GTGGCTCCCC AGGGCCTGGA GCGGGTTCCA 
GGTATCTTCA TCTCCCGCCT GGTACGTGGG GGCCTGGCTG AGAGTACAGG GCTGCTGGCG 
GTCAGTGATG AGATCCTTGA GGTCAACGGC ATTGAGGTGG CCGGGAAGAC CTTGGACCAA 
GTGACGGACA TGATGGTCGC CAACAGCCAC AACCTCATCG TCACTGTCAA GCCTGCCAAC 
CAGCGTAATA ATGTGGTACG GGGGGCATCT GGGCGTCTGA CAGGGCCTTC CTCTGTAGGG 
CCTGGGCCTA CTGATCCTGA CAGTGACGAT GACAGCAGTG ACCTGGTCAT TGAGAATCGC 
CACCCTCCCT GTTCTAATGG GCTGTCTCAG GGGCCCCTGT GCTGGGACCT GCAACCTGGC 
TGCCTACTTC CTGGTGCTGG CAGCTCTCTG CCCTCCTTGG ATAGCAGAGA GCAAGCCAAT 
TCTGGCTGGG GGAATGGCAT GCGAGGTGAT GTTAGCGGAT TCAGCCTCTG A

The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.

RefSeq NP_001273274.1
CDS95..1045
Translation

Target ORF information:

RefSeq Version NM_001286345.1
Organism Mus musculus(house mouse)
Definition Mus musculus par-6 family cell polarity regulator alpha (Pard6a), transcript variant 5, mRNA.

Target ORF information:

Epitope DYKDDDDK
Bacterial selection AMPR
Mammalian selection NeoR
Vector pcDNA3.1+/C-(K)DYK
 NM_001286345.1

ORF Insert Sequence:

1
61
121
181
241
301
361
421
481
541
601
661
721
781
841
901
ATGGCCAGGC CGCAGAGGAC TCCGGCGCGC AGTCCCGATA GCATCGTCGA GGTGAAGAGC 
AAATTTGACG CCGAGTTCCG ACGCTTTGCA CTACCCCGCA CTTCGGTGAG AGGCTTTCAG 
GAGTTCTCGC GATTGCTGTG TGTGGTACAC CAGATCCCTG GCCTGGACGT CCTGCTTGGC 
TATACGGATG CTCACGCAGA AGGTGACTCG AGTGGCCTGG CTTTTGCCTC CAACTCTCTA 
CAAAGGCGCA AGAAAGGGCT CCTGCTACGA CCAGTGGCAC CTCTGCGCAC CAGGCCACCC 
TTGTTAATCA GCTTGCCCCA AGATTTCCGC CAGGTGTCTT CAGTTATAGA TGTGGACCTA 
CTACCTGAGA CCCACCGACG AGTGAGGCTG CACAAACATG GTTCAGACCG TCCCCTGGGC 
TTCTACATTC GAGATGGCAT GAGTGTTCGC GTGGCTCCCC AGGGCCTGGA GCGGGTTCCA 
GGTATCTTCA TCTCCCGCCT GGTACGTGGG GGCCTGGCTG AGAGTACAGG GCTGCTGGCG 
GTCAGTGATG AGATCCTTGA GGTCAACGGC ATTGAGGTGG CCGGGAAGAC CTTGGACCAA 
GTGACGGACA TGATGGTCGC CAACAGCCAC AACCTCATCG TCACTGTCAA GCCTGCCAAC 
CAGCGTAATA ATGTGGTACG GGGGGCATCT GGGCGTCTGA CAGGGCCTTC CTCTGTAGGG 
CCTGGGCCTA CTGATCCTGA CAGTGACGAT GACAGCAGTG ACCTGGTCAT TGAGAATCGC 
CACCCTCCCT GTTCTAATGG GCTGTCTCAG GGGCCCCTGT GCTGGGACCT GCAACCTGGC 
TGCCTACTTC CTGGTGCTGG CAGCTCTCTG CCCTCCTTGG ATAGCAGAGA GCAAGCCAAT 
TCTGGCTGGG GGAATGGCAT GCGAGGTGAT GTTAGCGGAT TCAGCCTCTG A

The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.

CloneID OMu19773
Clone ID Related Accession (Same CDS sequence) NM_001047435.2
Accession Version NM_001047435.2 Latest version! Documents for ORF clone product in default vector
Sequence Information ORF Nucleotide Sequence (Length: 1038bp)
Protein sequence
SNP
Vector pcDNA3.1+/C-(K)DYK or customized vector User Manual
Clone information Clone Map MSDS
Tag on pcDNA3.1+/C-(K)DYK C terminal DYKDDDDK tags
ORF Insert Method CloneEZ™ Seamless cloning technology
Insert Structure linear
Update Date 2019-12-27
Organism Mus musculus(house mouse)
Product partitioning defective 6 homolog alpha isoform 2
Comment Comment: VALIDATED REFSEQ: This record has undergone validation or preliminary review. The reference sequence was derived from AC152826.2, AK158848.1 and BF466814.1. On Nov 2, 2013 this sequence version replaced NM_001047435.1. Transcript Variant: This variant (2) uses an alternate in-frame splice site in the 3' coding region, compared to variant 1. This results in a shorter protein (isoform 2), compared to isoform 1. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Gene record to access additional publications. ##Evidence-Data-START## Transcript exon combination :: AK158848.1, BC049593.1 [ECO:0000332] RNAseq introns :: single sample supports all introns SAMN00849374, SAMN00849375 [ECO:0000348] ##Evidence-Data-END## COMPLETENESS: complete on the 3' end. 

1
61
121
181
241
301
361
421
481
541
601
661
721
781
841
901
961
1021
ATGGCCAGGC CGCAGAGGAC TCCGGCGCGC AGTCCCGATA GCATCGTCGA GGTGAAGAGC 
AAATTTGACG CCGAGTTCCG ACGCTTTGCA CTACCCCGCA CTTCGGTGAG AGGCTTTCAG 
GAGTTCTCGC GATTGCTGTG TGTGGTACAC CAGATCCCTG GCCTGGACGT CCTGCTTGGC 
TATACGGATG CTCACGGTGA CTTGCTGCCC CTCACCAACG ATGACAGTTT GCACCGGGCC 
CTGGCCAGCG GGCCCCCACC TCTGCGCCTC TTGGTTCAGA AACGGGAAGG TGACTCGAGT 
GGCCTGGCTT TTGCCTCCAA CTCTCTACAA AGGCGCAAGA AAGGGCTCCT GCTACGACCA 
GTGGCACCTC TGCGCACCAG GCCACCCTTG TTAATCAGCT TGCCCCAAGA TTTCCGCCAG 
GTGTCTTCAG TTATAGATGT GGACCTACTA CCTGAGACCC ACCGACGAGT GAGGCTGCAC 
AAACATGGTT CAGACCGTCC CCTGGGCTTC TACATTCGAG ATGGCATGAG TGTTCGCGTG 
GCTCCCCAGG GCCTGGAGCG GGTTCCAGGT ATCTTCATCT CCCGCCTGGT ACGTGGGGGC 
CTGGCTGAGA GTACAGGGCT GCTGGCGGTC AGTGATGAGA TCCTTGAGGT CAACGGCATT 
GAGGTGGCCG GGAAGACCTT GGACCAAGTG ACGGACATGA TGGTCGCCAA CAGCCACAAC 
CTCATCGTCA CTGTCAAGCC TGCCAACCAG CGTAATAATG TGGTACGGGG GGCATCTGGG 
CGTCTGACAG GGCCTTCCTC TGTAGGGCCT GGGCCTACTG ATCCTGACAG TGACGATGAC 
AGCAGTGACC TGGTCATTGA GAATCGCCAC CCTCCCTGTT CTAATGGGCT GTCTCAGGGG 
CCCCTGTGCT GGGACCTGCA ACCTGGCTGC CTACTTCCTG GTGCTGGCAG CTCTCTGCCC 
TCCTTGGATA GCAGAGAGCA AGCCAATTCT GGCTGGGGGA ATGGCATGCG AGGTGATGTT 
AGCGGATTCA GCCTCTGA

The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.

RefSeq NP_001040900.1
CDS95..1132
Translation

Target ORF information:

RefSeq Version NM_001047435.2
Organism Mus musculus(house mouse)
Definition Mus musculus par-6 family cell polarity regulator alpha (Pard6a), transcript variant 2, mRNA.

Target ORF information:

Epitope DYKDDDDK
Bacterial selection AMPR
Mammalian selection NeoR
Vector pcDNA3.1+/C-(K)DYK
 NM_001047435.2

ORF Insert Sequence:

1
61
121
181
241
301
361
421
481
541
601
661
721
781
841
901
961
1021
ATGGCCAGGC CGCAGAGGAC TCCGGCGCGC AGTCCCGATA GCATCGTCGA GGTGAAGAGC 
AAATTTGACG CCGAGTTCCG ACGCTTTGCA CTACCCCGCA CTTCGGTGAG AGGCTTTCAG 
GAGTTCTCGC GATTGCTGTG TGTGGTACAC CAGATCCCTG GCCTGGACGT CCTGCTTGGC 
TATACGGATG CTCACGGTGA CTTGCTGCCC CTCACCAACG ATGACAGTTT GCACCGGGCC 
CTGGCCAGCG GGCCCCCACC TCTGCGCCTC TTGGTTCAGA AACGGGAAGG TGACTCGAGT 
GGCCTGGCTT TTGCCTCCAA CTCTCTACAA AGGCGCAAGA AAGGGCTCCT GCTACGACCA 
GTGGCACCTC TGCGCACCAG GCCACCCTTG TTAATCAGCT TGCCCCAAGA TTTCCGCCAG 
GTGTCTTCAG TTATAGATGT GGACCTACTA CCTGAGACCC ACCGACGAGT GAGGCTGCAC 
AAACATGGTT CAGACCGTCC CCTGGGCTTC TACATTCGAG ATGGCATGAG TGTTCGCGTG 
GCTCCCCAGG GCCTGGAGCG GGTTCCAGGT ATCTTCATCT CCCGCCTGGT ACGTGGGGGC 
CTGGCTGAGA GTACAGGGCT GCTGGCGGTC AGTGATGAGA TCCTTGAGGT CAACGGCATT 
GAGGTGGCCG GGAAGACCTT GGACCAAGTG ACGGACATGA TGGTCGCCAA CAGCCACAAC 
CTCATCGTCA CTGTCAAGCC TGCCAACCAG CGTAATAATG TGGTACGGGG GGCATCTGGG 
CGTCTGACAG GGCCTTCCTC TGTAGGGCCT GGGCCTACTG ATCCTGACAG TGACGATGAC 
AGCAGTGACC TGGTCATTGA GAATCGCCAC CCTCCCTGTT CTAATGGGCT GTCTCAGGGG 
CCCCTGTGCT GGGACCTGCA ACCTGGCTGC CTACTTCCTG GTGCTGGCAG CTCTCTGCCC 
TCCTTGGATA GCAGAGAGCA AGCCAATTCT GGCTGGGGGA ATGGCATGCG AGGTGATGTT 
AGCGGATTCA GCCTCTGA

The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.

PubMed

book

FRMD4A-cytohesin signaling modulates the cellular release of tau.
Journal of cell science129(10)2003-15(2016 05)
Yan X,Nyk?nen NP,Brunello CA,Haapasalo A,Hiltunen M,Uronen RL,Huttunen HJ


book

Zeb1 controls neuron differentiation and germinal zone exit by a mesenchymal-epithelial-like transition.
eLife5(2016 05)
Singh S,Howell D,Trivedi N,Kessler K,Ong T,Rosmaninho P,Raposo AA,Robinson G,Roussel MF,Castro DS,Solecki DJ


book

Antagonistic functions of Dishevelleds regulate Frizzled3 endocytosis via filopodia tips in Wnt-mediated growth cone guidance.
The Journal of neuroscience : the official journal of the Society for Neuroscience33(49)19071-85(2013 Dec)
Onishi K,Shafer B,Lo C,Tissir F,Goffinet AM,Zou Y


book

Loss of aPKC? in differentiated neurons disrupts the polarity complex but does not induce obvious neuronal loss or disorientation in mouse brains.
PloS one8(12)e84036(2013)
Yamanaka T,Tosaki A,Kurosawa M,Akimoto K,Hirose T,Ohno S,Hattori N,Nukina N