Gene Symbol | Rabgef1 |
Entrez Gene ID | 56715 |
Full Name | RAB guanine nucleotide exchange factor (GEF) 1 |
Synonyms | Rab5ef,Rabex5,Rin2 |
General protein information |
|
Gene Type | protein-coding |
Organism | Mus musculus(house mouse) |
Genome |
ORF » Species Summary » Mus musculus » Rabgef1 cDNA ORF clone
gRNAs
Gene Symbol | Rabgef1 |
Entrez Gene ID | 56715 |
Full Name | RAB guanine nucleotide exchange factor (GEF) 1 |
Synonyms | Rab5ef,Rabex5,Rin2 |
General protein information |
|
Gene Type | protein-coding |
Organism | Mus musculus(house mouse) |
Genome |
mRNA | Protein | Name |
---|---|---|
XM_006504447.3 | XP_006504510.1 | rab5 GDP/GTP exchange factor isoform X2 |
XM_006504446.4 | XP_006504509.1 | rab5 GDP/GTP exchange factor isoform X1 |
XM_006504448.3 | XP_006504511.1 | rab5 GDP/GTP exchange factor isoform X3 |
XM_006504446.3 | XP_006504509.1 | rab5 GDP/GTP exchange factor isoform X1 |
XM_006504448.2 | XP_006504511.1 | rab5 GDP/GTP exchange factor isoform X3 |
NM_001199059.1 | NP_001185988.1 | rab5 GDP/GTP exchange factor isoform a |
NM_001359233.1 | NP_001346162.1 | rab5 GDP/GTP exchange factor isoform b |
NM_019983.2 | NP_064367.1 | rab5 GDP/GTP exchange factor isoform a |
XM_017321033.1 | XP_017176522.1 | rab5 GDP/GTP exchange factor isoform X4 |
XM_006504447.4 | XP_006504510.1 | rab5 GDP/GTP exchange factor isoform X2 |
LOC695887 | XP_002803299.1 | |
Mus musculus (house mouse) | Rabgef1 | NP_001185988.1 |
Drosophila melanogaster (fruit fly) | Rabex-5 | NP_612093.1 |
Pan troglodytes (chimpanzee) | RABGEF1 | XP_003318527.1 |
Rattus norvegicus (Norway rat) | Rabgef1 | NP_001101803.1 |
Homo sapiens (human) | RABGEF1 | NP_001273990.1 |
Canis lupus familiaris (dog) | RABGEF1 | XP_005620983.1 |
Bos taurus (cattle) | RABGEF1 | NP_777016.1 |
Anopheles gambiae (African malaria mosquito) | AgaP_AGAP005551 | XP_315556.4 |
Caenorhabditis elegans (roundworm) | rabx-5 | NP_499337.3 |
Oryza sativa (rice) | Os03g0842700 | NP_001051858.1 |
Danio rerio (zebrafish) | rabgef1 | NP_957137.1 |
Guanine nucleotide exchange factor RABGEF1 regulates keratinocyte-intrinsic signaling to maintain skin homeostasis.
Marichal T, Gaudenzio N, El Abbas S, Sibilano R, Zurek O, Starkl P, Reber LL, Pirottin D, Kim J, Chambon P, Roers A, Antoine N, Kawakami Y, Kawakami T, Bureau F, Tam SY, Tsai M, Galli SJ
The Journal of clinical investigation126(12)4497-4515(2016 Dec)
Variants of Rab GTPase-Effector Binding Protein-2 Cause Variation in the Collateral Circulation and Severity of Stroke.
Lucitti JL, Sealock R, Buckley BK, Zhang H, Xiao L, Dudley AC, Faber JE
Stroke47(12)3022-3031(2016 Dec)
AP-1/?1A and AP-1/?1B adaptor-proteins differentially regulate neuronal early endosome maturation via the Rab5/Vps34-pathway.
Candiello E, Kratzke M, Wenzel D, Cassel D, Schu P
Scientific reports629950(2016 Jul)
Rab5 activity regulates GLUT4 sorting into insulin-responsive and non-insulin-responsive endosomal compartments: a potential mechanism for development of insulin resistance.
Tessneer KL, Jackson RM, Griesel BA, Olson AL
Endocrinology155(9)3315-28(2014 Sep)
RABEX-5 is upregulated and plays an oncogenic role in gastric cancer development by activating the VEGF signaling pathway.
Wang S, Lu A, Chen X, Wei L, Ding J
PloS one9(11)e113891(2014)
GeneRIFs: Gene References Into Functions What's a GeneRIF?
findings reveal a key role for RABGEF1 in dampening keratinocyte-intrinsic MYD88 signaling and sustaining epidermal barrier function
Title: Guanine nucleotide exchange factor RABGEF1 regulates keratinocyte-intrinsic signaling to maintain skin homeostasis.
Hyperinsulinemia induced insulin resistance in 3T3-L1 adipocytes by retaining GLUT4 in a Rab5-activity-dependent compartment.
Title: Rab5 activity regulates GLUT4 sorting into insulin-responsive and non-insulin-responsive endosomal compartments: a potential mechanism for development of insulin resistance.
Knockdown of RABEX-5 also inhibited wound healing, migration and the invasive abilities of gastric cancer cells.
Title: RABEX-5 is upregulated and plays an oncogenic role in gastric cancer development by activating the VEGF signaling pathway.
Rab5 is required for phagocytosis of heat-inactivated Pseudomonas aeruginosa by macrophages.
Title: Regulation of Rab5 function during phagocytosis of live Pseudomonas aeruginosa in macrophages.
Kruppel-like factor 5 is indispensable for adhesion, homing, lodging and retention of haematopoietic stem cells and progenitors in the bone marrow through Rab5-dependent post-translational regulation of beta1/beta2 integrins
Title: Klf5 controls bone marrow homing of stem cells and progenitors through Rab5-mediated ?1/?2-integrin trafficking.
The following Rabgef1 gene cDNA ORF clone sequences were retrieved from the NCBI Reference Sequence Database (RefSeq). These sequences represent the protein coding region of the Rabgef1 cDNA ORF which is encoded by the open reading frame (ORF) sequence. ORF sequences can be delivered in our standard vector, pcDNA3.1+/C-(K)DYK or the vector of your choice as an expression/transfection-ready ORF clone. Not the clone you want? Click here to find your clone.
CloneID | OMu18545 | |
Clone ID Related Accession (Same CDS sequence) | NM_001199059.1 , NM_019983.2 | |
Accession Version | NM_001199059.1 Latest version! | Documents for ORF clone product in default vector |
Sequence Information | ORF Nucleotide Sequence (Length: 1476bp) Protein sequence SNP |
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Vector | pcDNA3.1-C-(k)DYK or customized vector | ![]() |
Clone information | Clone Map | ![]() |
Tag on pcDNA3.1+/C-(K)DYK | C terminal DYKDDDDK tags | |
ORF Insert Method | CloneEZ™ Seamless cloning technology | |
Insert Structure | linear | |
Update Date | 2019-10-17 | |
Organism | Mus musculus(house mouse) | |
Product | rab5 GDP/GTP exchange factor isoform a | |
Comment | Comment: VALIDATED REFSEQ: This record has undergone validation or preliminary review. The reference sequence was derived from BY285547.1, AK146734.1 and BC018229.1. Transcript Variant: This variant (2) differs in the 5' UTR compared to variant 1. Variants 1 and 2 both encode the same isoform (a). Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Gene record to access additional publications. ##Evidence-Data-START## Transcript exon combination :: SRR1660817.139220.1, AF093590.1 [ECO:0000332] RNAseq introns :: single sample supports all introns SAMN00849375, SAMN00849380 [ECO:0000348] ##Evidence-Data-END## COMPLETENESS: complete on the 3' end. |
1 | ATGAGCCTGA AGTCCGAACG CAGGGGAATT CATGTGGATC AATCTGAGCT CCTGTGCAAG |
The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.
RefSeq | NP_001185988.1 |
CDS | 84..1559 |
Translation |
Target ORF information:
Target ORF information:
|
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1 | ATGAGCCTGA AGTCCGAACG CAGGGGAATT CATGTGGATC AATCTGAGCT CCTGTGCAAG |
The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.
CloneID | OMu18545 | |
Clone ID Related Accession (Same CDS sequence) | NM_001199059.1 , NM_019983.2 | |
Accession Version | NM_019983.2 Latest version! | Documents for ORF clone product in default vector |
Sequence Information | ORF Nucleotide Sequence (Length: 1476bp) Protein sequence SNP |
|
Vector | pcDNA3.1-C-(k)DYK or customized vector | ![]() |
Clone information | Clone Map | ![]() |
Tag on pcDNA3.1+/C-(K)DYK | C terminal DYKDDDDK tags | |
ORF Insert Method | CloneEZ™ Seamless cloning technology | |
Insert Structure | linear | |
Update Date | 2019-10-18 | |
Organism | Mus musculus(house mouse) | |
Product | rab5 GDP/GTP exchange factor isoform a | |
Comment | Comment: VALIDATED REFSEQ: This record has undergone validation or preliminary review. The reference sequence was derived from BC018229.1. On Jun 19, 2003 this sequence version replaced NM_019983.1. Transcript Variant: This variant (1) represents the longest transcript. Variants 1 and 2 both encode the same isoform (a). Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Gene record to access additional publications. ##Evidence-Data-START## Transcript exon combination :: BC018229.1, SRR1660813.270582.1 [ECO:0000332] RNAseq introns :: single sample supports all introns SAMN00849375, SAMN00849380 [ECO:0000348] ##Evidence-Data-END## COMPLETENESS: complete on the 3' end. |
1 | ATGAGCCTGA AGTCCGAACG CAGGGGAATT CATGTGGATC AATCTGAGCT CCTGTGCAAG |
The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.
RefSeq | NP_064367.1 |
CDS | 229..1704 |
Translation |
Target ORF information:
Target ORF information:
|
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1 | ATGAGCCTGA AGTCCGAACG CAGGGGAATT CATGTGGATC AATCTGAGCT CCTGTGCAAG |
The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.
CloneID | OMu36158 | |
Clone ID Related Accession (Same CDS sequence) | NM_001359233.1 , XM_017321033.1 | |
Accession Version | NM_001359233.1 Latest version! | Documents for ORF clone product in default vector |
Sequence Information | ORF Nucleotide Sequence (Length: 900bp) Protein sequence SNP |
|
Vector | pcDNA3.1-C-(k)DYK or customized vector | ![]() |
Clone information | Clone Map | ![]() |
Tag on pcDNA3.1+/C-(K)DYK | C terminal DYKDDDDK tags | |
ORF Insert Method | CloneEZ™ Seamless cloning technology | |
Insert Structure | linear | |
Update Date | 2019-10-21 | |
Organism | Mus musculus(house mouse) | |
Product | rab5 GDP/GTP exchange factor isoform b | |
Comment | Comment: VALIDATED REFSEQ: This record has undergone validation or preliminary review. The reference sequence was derived from AC122339.3 and AC113029.23. On Dec 29, 2017 this sequence version replaced XM_017321033.1. Transcript Variant: This variant (3) lacks an alternate exon compared to variant 1. The resulting isoform (b) is shorter at the N-terminus compared to isoform a. Sequence Note: The RefSeq transcript and protein were derived from genomic sequence to make the sequence consistent with the reference genome assembly. The genomic coordinates used for the transcript record were based on alignments. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Gene record to access additional publications. ##Evidence-Data-START## Transcript exon combination :: SRR1660815.43383.1 [ECO:0000332] RNAseq introns :: single sample supports all introns SAMN00849377, SAMN00849381 [ECO:0000348] ##Evidence-Data-END## COMPLETENESS: complete on the 3' end. |
1 | ATGCAGACCC GTGGGAAAGT GCCTCCAGAG AAAGTGGAGA AGATAATGGA TCAGATCGAA |
The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.
RefSeq | NP_001346162.1 |
CDS | 493..1392 |
Translation |
Target ORF information:
Target ORF information:
|
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1 | ATGCAGACCC GTGGGAAAGT GCCTCCAGAG AAAGTGGAGA AGATAATGGA TCAGATCGAA |
The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.
CloneID | OMu36155 | |
Clone ID Related Accession (Same CDS sequence) | XM_006504446.4 , XM_006504446.3 | |
Accession Version | XM_006504446.3 | Documents for ORF clone product in default vector |
Sequence Information | ORF Nucleotide Sequence (Length: 1533bp) Protein sequence SNP |
|
Vector | pcDNA3.1-C-(k)DYK or customized vector | ![]() |
Clone information | Clone Map | ![]() |
Tag on pcDNA3.1+/C-(K)DYK | C terminal DYKDDDDK tags | |
ORF Insert Method | CloneEZ™ Seamless cloning technology | |
Insert Structure | linear | |
Update Date | 2016-06-21 | |
Organism | Mus musculus(house mouse) | |
Product | rab5 GDP/GTP exchange factor isoform X1 | |
Comment | Comment: MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_000071.6) annotated using gene prediction method: Gnomon, supported by EST evidence. Also see: Documentation of NCBI's Annotation Process On Jun 22, 2016 this sequence version replaced XM_006504446.2. ##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Version :: Mus musculus Annotation Release 106 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 7.1 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END## |
1 | ATGAGAAGTC CTGAAGCTGA GGCAGGAGGA TTGCCGCGAG TTTTGAGGAA GAAGATGAGC |
The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.
RefSeq | XP_006504509.1 |
CDS | 330..1862 |
Translation |
Target ORF information:
Target ORF information:
|
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1 | ATGAGAAGTC CTGAAGCTGA GGCAGGAGGA TTGCCGCGAG TTTTGAGGAA GAAGATGAGC |
The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.
CloneID | OMu36156 | |
Clone ID Related Accession (Same CDS sequence) | XM_006504447.3 , XM_006504447.4 | |
Accession Version | XM_006504447.3 | Documents for ORF clone product in default vector |
Sequence Information | ORF Nucleotide Sequence (Length: 1530bp) Protein sequence SNP |
|
Vector | pcDNA3.1-C-(k)DYK or customized vector | ![]() |
Clone information | Clone Map | ![]() |
Tag on pcDNA3.1+/C-(K)DYK | C terminal DYKDDDDK tags | |
ORF Insert Method | CloneEZ™ Seamless cloning technology | |
Insert Structure | linear | |
Update Date | 2016-06-21 | |
Organism | Mus musculus(house mouse) | |
Product | rab5 GDP/GTP exchange factor isoform X2 | |
Comment | Comment: MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_000071.6) annotated using gene prediction method: Gnomon, supported by mRNA and EST evidence. Also see: Documentation of NCBI's Annotation Process On Jun 22, 2016 this sequence version replaced XM_006504447.2. ##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Version :: Mus musculus Annotation Release 106 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 7.1 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END## |
1 | ATGAGAAGTC CTGAAGCTGA GGCAGGAGGA TTGCCGCGAG TTTTGAGGAA GAAGATGAGC |
The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.
RefSeq | XP_006504510.1 |
CDS | 330..1859 |
Translation |
Target ORF information:
Target ORF information:
|
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1 | ATGAGAAGTC CTGAAGCTGA GGCAGGAGGA TTGCCGCGAG TTTTGAGGAA GAAGATGAGC |
The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.
CloneID | OMu36157 | |
Clone ID Related Accession (Same CDS sequence) | XM_006504448.3 , XM_006504448.2 | |
Accession Version | XM_006504448.2 | Documents for ORF clone product in default vector |
Sequence Information | ORF Nucleotide Sequence (Length: 1479bp) Protein sequence SNP |
|
Vector | pcDNA3.1-C-(k)DYK or customized vector | ![]() |
Clone information | Clone Map | ![]() |
Tag on pcDNA3.1+/C-(K)DYK | C terminal DYKDDDDK tags | |
ORF Insert Method | CloneEZ™ Seamless cloning technology | |
Insert Structure | linear | |
Update Date | 2016-06-21 | |
Organism | Mus musculus(house mouse) | |
Product | rab5 GDP/GTP exchange factor isoform X3 | |
Comment | Comment: MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_000071.6) annotated using gene prediction method: Gnomon, supported by EST evidence. Also see: Documentation of NCBI's Annotation Process On Jun 22, 2016 this sequence version replaced XM_006504448.1. ##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Version :: Mus musculus Annotation Release 106 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 7.1 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END## |
1 | ATGAGCCTGA AGTCCGAACG CAGGGGAATT CATGTGGATC AATCTGAGCT CCTGTGCAAG |
The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.
RefSeq | XP_006504511.1 |
CDS | 112..1590 |
Translation |
Target ORF information:
Target ORF information:
|
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1 | ATGAGCCTGA AGTCCGAACG CAGGGGAATT CATGTGGATC AATCTGAGCT CCTGTGCAAG |
The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.
CloneID | OMu36158 | |
Clone ID Related Accession (Same CDS sequence) | NM_001359233.1 , XM_017321033.1 | |
Accession Version | XM_017321033.1 Latest version! | Documents for ORF clone product in default vector |
Sequence Information | ORF Nucleotide Sequence (Length: 900bp) Protein sequence SNP |
|
Vector | pcDNA3.1-C-(k)DYK or customized vector | ![]() |
Clone information | Clone Map | ![]() |
Tag on pcDNA3.1+/C-(K)DYK | C terminal DYKDDDDK tags | |
ORF Insert Method | CloneEZ™ Seamless cloning technology | |
Insert Structure | linear | |
Update Date | 2016-06-21 | |
Organism | Mus musculus(House mouse) | |
Product | rab5 GDP/GTP exchange factor isoform X4 | |
Comment | MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_000071.6) annotated using gene prediction method: Gnomon, supported by EST evidence. Also see: Documentation of NCBI's Annotation Process ##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Version :: Mus musculus Annotation Release 106 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 7.1 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END## |
1 | ATGCAGACCC GTGGGAAAGT GCCTCCAGAG AAAGTGGAGA AGATAATGGA TCAGATCGAA |
The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.
RefSeq | XP_017176522.1 |
CDS | 470..1369 |
Translation |
Target ORF information:
Target ORF information:
|
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1 | ATGCAGACCC GTGGGAAAGT GCCTCCAGAG AAAGTGGAGA AGATAATGGA TCAGATCGAA |
The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.
CloneID | OMu36157 | |
Clone ID Related Accession (Same CDS sequence) | XM_006504448.3 , XM_006504448.2 | |
Accession Version | XM_006504448.3 Latest version! | Documents for ORF clone product in default vector |
Sequence Information | ORF Nucleotide Sequence (Length: 1479bp) Protein sequence SNP |
|
Vector | pcDNA3.1-C-(k)DYK or customized vector | ![]() |
Clone information | Clone Map | ![]() |
Tag on pcDNA3.1+/C-(K)DYK | C terminal DYKDDDDK tags | |
ORF Insert Method | CloneEZ™ Seamless cloning technology | |
Insert Structure | linear | |
Update Date | 2019-08-07 | |
Organism | Mus musculus(house mouse) | |
Product | rab5 GDP/GTP exchange factor isoform X3 | |
Comment | Comment: MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_000071.6) annotated using gene prediction method: Gnomon, supported by EST evidence. Also see: Documentation of NCBI's Annotation Process On Aug 8, 2019 this sequence version replaced XM_006504448.2. ##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Name :: Mus musculus Annotation Release 108 Annotation Version :: 108 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 8.2 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END## |
1 | ATGAGCCTGA AGTCCGAACG CAGGGGAATT CATGTGGATC AATCTGAGCT CCTGTGCAAG |
The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.
RefSeq | XP_006504511.1 |
CDS | 112..1590 |
Translation |
Target ORF information:
Target ORF information:
|
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1 | ATGAGCCTGA AGTCCGAACG CAGGGGAATT CATGTGGATC AATCTGAGCT CCTGTGCAAG |
The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.
CloneID | OMu36155 | |
Clone ID Related Accession (Same CDS sequence) | XM_006504446.4 , XM_006504446.3 | |
Accession Version | XM_006504446.4 Latest version! | Documents for ORF clone product in default vector |
Sequence Information | ORF Nucleotide Sequence (Length: 1533bp) Protein sequence SNP |
|
Vector | pcDNA3.1-C-(k)DYK or customized vector | ![]() |
Clone information | Clone Map | ![]() |
Tag on pcDNA3.1+/C-(K)DYK | C terminal DYKDDDDK tags | |
ORF Insert Method | CloneEZ™ Seamless cloning technology | |
Insert Structure | linear | |
Update Date | 2019-08-07 | |
Organism | Mus musculus(house mouse) | |
Product | rab5 GDP/GTP exchange factor isoform X1 | |
Comment | Comment: MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_000071.6) annotated using gene prediction method: Gnomon, supported by EST evidence. Also see: Documentation of NCBI's Annotation Process On Aug 8, 2019 this sequence version replaced XM_006504446.3. ##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Name :: Mus musculus Annotation Release 108 Annotation Version :: 108 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 8.2 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END## |
1 | ATGAGAAGTC CTGAAGCTGA GGCAGGAGGA TTGCCGCGAG TTTTGAGGAA GAAGATGAGC |
The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.
RefSeq | XP_006504509.1 |
CDS | 276..1808 |
Translation |
Target ORF information:
Target ORF information:
|
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1 | ATGAGAAGTC CTGAAGCTGA GGCAGGAGGA TTGCCGCGAG TTTTGAGGAA GAAGATGAGC |
The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.
CloneID | OMu36156 | |
Clone ID Related Accession (Same CDS sequence) | XM_006504447.3 , XM_006504447.4 | |
Accession Version | XM_006504447.4 Latest version! | Documents for ORF clone product in default vector |
Sequence Information | ORF Nucleotide Sequence (Length: 1530bp) Protein sequence SNP |
|
Vector | pcDNA3.1-C-(k)DYK or customized vector | ![]() |
Clone information | Clone Map | ![]() |
Tag on pcDNA3.1+/C-(K)DYK | C terminal DYKDDDDK tags | |
ORF Insert Method | CloneEZ™ Seamless cloning technology | |
Insert Structure | linear | |
Update Date | 2019-08-07 | |
Organism | Mus musculus(house mouse) | |
Product | rab5 GDP/GTP exchange factor isoform X2 | |
Comment | Comment: MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_000071.6) annotated using gene prediction method: Gnomon, supported by mRNA and EST evidence. Also see: Documentation of NCBI's Annotation Process On Aug 8, 2019 this sequence version replaced XM_006504447.3. ##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Name :: Mus musculus Annotation Release 108 Annotation Version :: 108 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 8.2 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END## |
1 | ATGAGAAGTC CTGAAGCTGA GGCAGGAGGA TTGCCGCGAG TTTTGAGGAA GAAGATGAGC |
The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.
RefSeq | XP_006504510.1 |
CDS | 301..1830 |
Translation |
Target ORF information:
Target ORF information:
|
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1 | ATGAGAAGTC CTGAAGCTGA GGCAGGAGGA TTGCCGCGAG TTTTGAGGAA GAAGATGAGC |
The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.
Guanine nucleotide exchange factor RABGEF1 regulates keratinocyte-intrinsic signaling to maintain skin homeostasis. |
Variants of Rab GTPase-Effector Binding Protein-2 Cause Variation in the Collateral Circulation and Severity of Stroke. |
AP-1/?1A and AP-1/?1B adaptor-proteins differentially regulate neuronal early endosome maturation via the Rab5/Vps34-pathway. |
Rab5 activity regulates GLUT4 sorting into insulin-responsive and non-insulin-responsive endosomal compartments: a potential mechanism for development of insulin resistance. |
RABEX-5 is upregulated and plays an oncogenic role in gastric cancer development by activating the VEGF signaling pathway. |