Gene Symbol | Bcam |
Entrez Gene ID | 57278 |
Full Name | basal cell adhesion molecule |
Synonyms | 1200005K12Rik,B-CAM,Gplu,Lu |
General protein information |
|
Gene Type | protein-coding |
Organism | Mus musculus(house mouse) |
Genome |
ORF » Species Summary » Mus musculus » Bcam cDNA ORF clone
Gene Symbol | Bcam |
Entrez Gene ID | 57278 |
Full Name | basal cell adhesion molecule |
Synonyms | 1200005K12Rik,B-CAM,Gplu,Lu |
General protein information |
|
Gene Type | protein-coding |
Organism | Mus musculus(house mouse) |
Genome |
mRNA | Protein | Name |
---|---|---|
NM_020486.2 | NP_065232.1 | basal cell adhesion molecule precursor |
Homo sapiens (human) | BCAM | NP_005572.2 |
Danio rerio (zebrafish) | bcam | NP_001070095.1 |
Danio rerio (zebrafish) | LOC100536698 | XP_003201751.2 |
Pan troglodytes (chimpanzee) | BCAM | XP_001161955.3 |
Canis lupus familiaris (dog) | BCAM | XP_541571.4 |
Xenopus tropicalis (tropical clawed frog) | bcam | XP_002941084.2 |
Rattus norvegicus (Norway rat) | Bcam | NP_113940.1 |
Bos taurus (cattle) | BCAM | NP_777166.1 |
Mus musculus (house mouse) | Bcam | NP_065232.1 |
BCAM | XP_002801340.1 |
Cell-matrix signals specify bone endothelial cells during developmental osteogenesis.
Langen UH, Pitulescu ME, Kim JM, Enriquez-Gasca R, Sivaraj KK, Kusumbe AP, Singh A, Di Russo J, Bixel MG, Zhou B, Sorokin L, Vaquerizas JM, Adams RH
Nature cell biology19(3)189-201(2017 Mar)
YAP is essential for mechanical force production and epithelial cell proliferation during lung branching morphogenesis.
Lin C, Yao E, Zhang K, Jiang X, Croll S, Thompson-Peer K, Chuang PT
eLife6(2017 Mar)
Expression of the immunoglobulin superfamily cell adhesion molecules in the developing spinal cord and dorsal root ganglion.
Gu Z, Imai F, Kim IJ, Fujita H, Katayama Ki, Mori K, Yoshihara Y, Yoshida Y
PloS one10(3)e0121550(2015)
Lutheran/basal cell adhesion molecule accelerates progression of crescentic glomerulonephritis in mice.
Huang J, Filipe A, Rahuel C, Bonnin P, Mesnard L, Gu?rin C, Wang Y, Le Van Kim C, Colin Y, Tharaux PL
Kidney international85(5)1123-36(2014 May)
GeneRIFs: Gene References Into Functions What's a GeneRIF?
Lu/BCAM may have a critical role in facilitating the accumulation of monocytes and macrophages, thereby exacerbating renal injury in crescentic glomerulonephritis.
Title: Lutheran/basal cell adhesion molecule accelerates progression of crescentic glomerulonephritis in mice.
Lutheran (Lu), also known as basal cell adhesion molecule (B-CAM), competes with integrins for binding to laminin alpha5, a subunit of LM-511, a major component of basement membranes.
Title: The lutheran/basal cell adhesion molecule promotes tumor cell migration by modulating integrin-mediated cell attachment to laminin-511 protein.
Lu/BCAM, as a laminin receptor, is involved in vivo in the maintenance of normal basement membrane organization in the kidney and intestine.
Title: Genetic inactivation of the laminin alpha5 chain receptor Lu/BCAM leads to kidney and intestinal abnormalities in the mouse.
The following Bcam gene cDNA ORF clone sequences were retrieved from the NCBI Reference Sequence Database (RefSeq). These sequences represent the protein coding region of the Bcam cDNA ORF which is encoded by the open reading frame (ORF) sequence. ORF sequences can be delivered in our standard vector, pcDNA3.1+/C-(K)DYK or the vector of your choice as an expression/transfection-ready ORF clone. Not the clone you want? Click here to find your clone.
CloneID | OMu12030 | |
Clone ID Related Accession (Same CDS sequence) | NM_020486.2 | |
Accession Version | NM_020486.2 Latest version! | Documents for ORF clone product in default vector |
Sequence Information | ORF Nucleotide Sequence (Length: 1869bp) Protein sequence SNP |
|
Vector | pcDNA3.1-C-(k)DYK or customized vector | User Manual |
Clone information | Clone Map | MSDS |
Tag on pcDNA3.1+/C-(K)DYK | C terminal DYKDDDDK tags | |
ORF Insert Method | CloneEZ™ Seamless cloning technology | |
Insert Structure | linear | |
Update Date | 2019-12-25 | |
Organism | Mus musculus(house mouse) | |
Product | basal cell adhesion molecule precursor | |
Comment | Comment: VALIDATED REFSEQ: This record has undergone validation or preliminary review. The reference sequence was derived from AF109160.1, AF221507.1, AF346663.1 and BB190832.1. On Dec 9, 2006 this sequence version replaced NM_020486.1. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Gene record to access additional publications. ##Evidence-Data-START## Transcript exon combination :: AB035511.1, AK075704.1 [ECO:0000332] RNAseq introns :: mixed/partial sample support SAMN00849374, SAMN00849375 [ECO:0000350] ##Evidence-Data-END## |
1 | ATGGAACCCC CTGACGCCCG CGCAGGGCTG CTGTGGCTCA CCTTCCTGCT GTCGGGCTAC |
The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.
RefSeq | NP_065232.1 |
CDS | 63..1931 |
Translation |
Target ORF information:
Target ORF information:
|
NM_020486.2 |
1 | ATGGAACCCC CTGACGCCCG CGCAGGGCTG CTGTGGCTCA CCTTCCTGCT GTCGGGCTAC |
The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.
Cell-matrix signals specify bone endothelial cells during developmental osteogenesis. |
YAP is essential for mechanical force production and epithelial cell proliferation during lung branching morphogenesis. |
Expression of the immunoglobulin superfamily cell adhesion molecules in the developing spinal cord and dorsal root ganglion. |
Lutheran/basal cell adhesion molecule accelerates progression of crescentic glomerulonephritis in mice. |