Gene Symbol | Jph3 |
Entrez Gene ID | 57340 |
Full Name | junctophilin 3 |
Synonyms | JP-3,Jp3 |
General protein information |
|
Gene Type | protein-coding |
Organism | Mus musculus(house mouse) |
Genome |
ORF » Species Summary » Mus musculus » Jph3 cDNA ORF clone
gRNAs
Gene Symbol | Jph3 |
Entrez Gene ID | 57340 |
Full Name | junctophilin 3 |
Synonyms | JP-3,Jp3 |
General protein information |
|
Gene Type | protein-coding |
Organism | Mus musculus(house mouse) |
Genome |
mRNA | Protein | Name |
---|---|---|
NM_020605.3 | NP_065630.1 | junctophilin-3 |
Homo sapiens (human) | JPH3 | NP_065706.2 |
Pan troglodytes (chimpanzee) | JPH3 | XP_001153256.2 |
Canis lupus familiaris (dog) | JPH3 | XP_546789.2 |
Mus musculus (house mouse) | Jph3 | NP_065630.1 |
Rattus norvegicus (Norway rat) | Jph3 | NP_001100907.1 |
Gallus gallus (chicken) | JPH3 | XP_414192.1 |
Danio rerio (zebrafish) | LOC569861 | NP_001116174.1 |
LOC704611 | XP_001092976.2 | |
Bos taurus (cattle) | JPH3 | NP_001192548.1 |
Xenopus tropicalis (tropical clawed frog) | jph3 | XP_002936140.2 |
Junctophilin 3 expresses in pancreatic beta cells and is required for glucose-stimulated insulin secretion.
Li L, Pan ZF, Huang X, Wu BW, Li T, Kang MX, Ge RS, Hu XY, Zhang YH, Ge LJ, Zhu DY, Wu YL, Lou YJ
Cell death & disease7(6)e2275(2016 Jun)
Abnormal features in mutant cerebellar Purkinje cells lacking junctophilins.
Ikeda A, Miyazaki T, Kakizawa S, Okuno Y, Tsuchiya S, Myomoto A, Saito SY, Yamamoto T, Yamazaki T, Iino M, Tsujimoto G, Watanabe M, Takeshima H
Biochemical and biophysical research communications363(3)835-9(2007 Nov)
Qualitative and quantitative analyses of protein phosphorylation in naive and stimulated mouse synaptosomal preparations.
Munton RP, Tweedie-Cullen R, Livingstone-Zatchej M, Weinandy F, Waidelich M, Longo D, Gehrig P, Potthast F, Rutishauser D, Gerrits B, Panse C, Schlapbach R, Mansuy IM
Molecular & cellular proteomics : MCP6(2)283-93(2007 Feb)
Functional uncoupling between Ca2+ release and afterhyperpolarization in mutant hippocampal neurons lacking junctophilins.
Moriguchi S, Nishi M, Komazaki S, Sakagami H, Miyazaki T, Masumiya H, Saito SY, Watanabe M, Kondo H, Yawo H, Fukunaga K, Takeshima H
Proceedings of the National Academy of Sciences of the United States of America103(28)10811-6(2006 Jul)
Comprehensive identification of phosphorylation sites in postsynaptic density preparations.
Trinidad JC, Specht CG, Thalhammer A, Schoepfer R, Burlingame AL
Molecular & cellular proteomics : MCP5(5)914-22(2006 May)
GeneRIFs: Gene References Into Functions What's a GeneRIF?
The expression of JPH isoforms was examined in human and mouse pancreatic tissues, and JPH3 expression was found in both the beta cells.
Title: Junctophilin 3 expresses in pancreatic beta cells and is required for glucose-stimulated insulin secretion.
Gene expression was slightly altered in the JP-3 and JP-4 Knockout cerebellum.
Title: Abnormal features in mutant cerebellar Purkinje cells lacking junctophilins.
Motor discoordination in mutant mice lacking junctophilin type 3
Title: Motor discoordination in mutant mice lacking junctophilin type 3.
The following Jph3 gene cDNA ORF clone sequences were retrieved from the NCBI Reference Sequence Database (RefSeq). These sequences represent the protein coding region of the Jph3 cDNA ORF which is encoded by the open reading frame (ORF) sequence. ORF sequences can be delivered in our standard vector, pcDNA3.1+/C-(K)DYK or the vector of your choice as an expression/transfection-ready ORF clone. Not the clone you want? Click here to find your clone.
CloneID | OMu12062 | |
Clone ID Related Accession (Same CDS sequence) | NM_020605.3 | |
Accession Version | NM_020605.3 Latest version! | Documents for ORF clone product in default vector |
Sequence Information | ORF Nucleotide Sequence (Length: 2235bp) Protein sequence SNP |
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Vector | pcDNA3.1-C-(k)DYK or customized vector | ![]() |
Clone information | Clone Map | ![]() |
Tag on pcDNA3.1+/C-(K)DYK | C terminal DYKDDDDK tags | |
ORF Insert Method | CloneEZ™ Seamless cloning technology | |
Insert Structure | linear | |
Update Date | 2019-12-27 | |
Organism | Mus musculus(house mouse) | |
Product | junctophilin-3 | |
Comment | Comment: VALIDATED REFSEQ: This record has undergone validation or preliminary review. The reference sequence was derived from BY718602.1, AB024449.1 and AC121975.3. On Mar 24, 2011 this sequence version replaced NM_020605.2. Sequence Note: This RefSeq record was created from transcript and genomic sequence data to make the sequence consistent with the reference genome assembly. The genomic coordinates used for the transcript record were based on transcript alignments. ##Evidence-Data-START## Transcript exon combination :: SRR1660815.147366.1, SRR1660817.309665.1 [ECO:0000332] RNAseq introns :: single sample supports all introns SAMN00849377, SAMN00849379 [ECO:0000348] ##Evidence-Data-END## COMPLETENESS: complete on the 3' end. |
1 | ATGTCCAGTG GGGGTAGGTT TAATTTTGAC GATGGAGGGT CCTACTGCGG AGGCTGGGAG |
The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.
RefSeq | NP_065630.1 |
CDS | 65..2299 |
Translation |
Target ORF information:
Target ORF information:
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1 | ATGTCCAGTG GGGGTAGGTT TAATTTTGAC GATGGAGGGT CCTACTGCGG AGGCTGGGAG |
The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.
Junctophilin 3 expresses in pancreatic beta cells and is required for glucose-stimulated insulin secretion. |
Abnormal features in mutant cerebellar Purkinje cells lacking junctophilins. |
Qualitative and quantitative analyses of protein phosphorylation in naive and stimulated mouse synaptosomal preparations. |
Functional uncoupling between Ca2+ release and afterhyperpolarization in mutant hippocampal neurons lacking junctophilins. |
Comprehensive identification of phosphorylation sites in postsynaptic density preparations. |