Gene Symbol | Smoc1 |
Entrez Gene ID | 64075 |
Full Name | SPARC related modular calcium binding 1 |
Synonyms | 2600002F22Rik,AI848508,SRG |
General protein information |
|
Gene Type | protein-coding |
Organism | Mus musculus(house mouse) |
Genome |
ORF » Species Summary » Mus musculus » Smoc1 cDNA ORF clone
gRNAs
Gene Symbol | Smoc1 |
Entrez Gene ID | 64075 |
Full Name | SPARC related modular calcium binding 1 |
Synonyms | 2600002F22Rik,AI848508,SRG |
General protein information |
|
Gene Type | protein-coding |
Organism | Mus musculus(house mouse) |
Genome |
mRNA | Protein | Name |
---|---|---|
NM_001146217.1 | NP_001139689.1 | SPARC-related modular calcium-binding protein 1 isoform 1 precursor |
NM_022316.2 | NP_071711.2 | SPARC-related modular calcium-binding protein 1 isoform 2 precursor |
XM_006516135.3 | XP_006516198.1 | SPARC-related modular calcium-binding protein 1 isoform X1 |
XM_006516135.4 | XP_006516198.1 | SPARC-related modular calcium-binding protein 1 isoform X1 |
Homo sapiens (human) | SMOC1 | NP_001030024.1 |
Pan troglodytes (chimpanzee) | SMOC1 | XP_510036.4 |
Mus musculus (house mouse) | Smoc1 | NP_001139689.1 |
Rattus norvegicus (Norway rat) | Smoc1 | NP_001002835.1 |
Bos taurus (cattle) | SMOC1 | NP_001073239.1 |
LOC712994 | XP_001110348.2 | |
Canis lupus familiaris (dog) | SMOC1 | XP_005623640.1 |
Gallus gallus (chicken) | SMOC1 | XP_001231761.2 |
Danio rerio (zebrafish) | smoc1 | NP_001188322.1 |
Xenopus tropicalis (tropical clawed frog) | smoc1 | NP_001120579.1 |
High-throughput discovery of novel developmental phenotypes.
Dickinson ME, Flenniken AM, Ji X, Teboul L, Wong MD, White JK, Meehan TF, Weninger WJ, Westerberg H, Adissu H, Baker CN, Bower L, Brown JM, Caddle LB, Chiani F, Clary D, Cleak J, Daly MJ, Denegre JM, Doe B, Dolan ME, Edie SM, Fuchs H, Gailus-Durner V, Galli A, Gambadoro A, Gallegos J, Guo S, Horner NR, Hsu CW, Johnson SJ, Kalaga S, Keith LC, Lanoue L, Lawson TN, Lek M, Mark M, Marschall S, Mason J, McElwee ML, Newbigging S, Nutter LM, Peterson KA, Ramirez-Solis R, Rowland DJ, Ryder E, Samocha KE, Seavitt JR, Selloum M, Szoke-Kovacs Z, Tamura M, Trainor AG, Tudose I, Wakana S, Warren J, Wendling O, West DB, Wong L, Yoshiki A, , , , , , , , , MacArthur DG, Tocchini-Valentini GP, Gao X, Flicek P, Bradley A, Skarnes WC, Justice MJ, Parkinson HE, Moore M, Wells S, Braun RE, Svenson KL, de Angelis MH, Herault Y, Mohun T, Mallon AM, Henkelman RM, Brown SD, Adams DJ, Lloyd KC, McKerlie C, Beaudet AL, Bu?an M, Murray SA
Nature537(7621)508-514(2016 09)
Pbx Regulates Patterning of the Cerebral Cortex in Progenitors and Postmitotic Neurons.
Golonzhka O, Nord A, Tang PL, Lindtner S, Ypsilanti AR, Ferretti E, Visel A, Selleri L, Rubenstein JL
Neuron88(6)1192-207(2015 Dec)
Spatiotemporal regulation of GLI target genes in the mammalian limb bud.
Lewandowski JP, Du F, Zhang S, Powell MB, Falkenstein KN, Ji H, Vokes SA
Developmental biology406(1)92-103(2015 Oct)
GeneRIFs: Gene References Into Functions What's a GeneRIF?
SMOC1 is an activin-like kinase antagonist produced by endothelial cells that tips TGF-beta signalling towards ALK1 activation
Title: Role of secreted modular calcium-binding protein 1 (SMOC1) in transforming growth factor ? signalling and angiogenesis.
The heparin-binding activity of secreted modular calcium-binding protein 1 (SMOC-1) modulates its cell adhesion properties.
Title: The heparin-binding activity of secreted modular calcium-binding protein 1 (SMOC-1) modulates its cell adhesion properties.
these findings indicate that SMOC1/Smoc1 is essential for ocular and limb development in both humans and mice.
Title: SMOC1 is essential for ocular and limb development in humans and mice.
SMOC1 and SMOC2 may mediate intercellular signaling and cell type-specific differentiation during gonad and reproductive tract development
Title: Developmental expression of Smoc1 and Smoc2 suggests potential roles in fetal gonad and reproductive tract differentiation.
expression of SMOC-1 examined in the early embryo day 7, as well as in following embryonic stages on days 12, 14, 16 & 18; broad and organ-specific distribution suggests multifunctional roles of SMOC-1 during mouse embryogenesis
Title: Secreted modular calcium-binding protein-1 localization during mouse embryogenesis.
The following Smoc1 gene cDNA ORF clone sequences were retrieved from the NCBI Reference Sequence Database (RefSeq). These sequences represent the protein coding region of the Smoc1 cDNA ORF which is encoded by the open reading frame (ORF) sequence. ORF sequences can be delivered in our standard vector, pcDNA3.1+/C-(K)DYK or the vector of your choice as an expression/transfection-ready ORF clone. Not the clone you want? Click here to find your clone.
CloneID | OMu07272 | |
Clone ID Related Accession (Same CDS sequence) | NM_001146217.1 | |
Accession Version | NM_001146217.1 Latest version! | Documents for ORF clone product in default vector |
Sequence Information | ORF Nucleotide Sequence (Length: 1392bp) Protein sequence SNP |
|
Vector | pcDNA3.1-C-(k)DYK or customized vector | ![]() |
Clone information | Clone Map | ![]() |
Tag on pcDNA3.1+/C-(K)DYK | C terminal DYKDDDDK tags | |
ORF Insert Method | CloneEZ™ Seamless cloning technology | |
Insert Structure | linear | |
Update Date | 2019-12-09 | |
Organism | Mus musculus(house mouse) | |
Product | SPARC-related modular calcium-binding protein 1 isoform 1 precursor | |
Comment | Comment: VALIDATED REFSEQ: This record has undergone validation or preliminary review. The reference sequence was derived from AK040931.1 and AC124384.4. Transcript Variant: This variant (1) represents the longer transcript and encodes the longer isoform (1). Sequence Note: This RefSeq record was created from transcript and genomic sequence data to make the sequence consistent with the reference genome assembly. The genomic coordinates used for the transcript record were based on transcript alignments. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Gene record to access additional publications. ##Evidence-Data-START## Transcript exon combination :: AK040931.1 [ECO:0000332] RNAseq introns :: single sample supports all introns SAMN00849374, SAMN00849375 [ECO:0000348] ##Evidence-Data-END## COMPLETENESS: complete on the 3' end. |
1 | ATGCTGCCCG CGCGCGTCCG TCTGCTCACG CCCCACTTGC TGCTCGTGTT GGTGCAGCTG |
The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.
RefSeq | NP_001139689.1 |
CDS | 256..1647 |
Translation |
Target ORF information:
Target ORF information:
|
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1 | ATGCTGCCCG CGCGCGTCCG TCTGCTCACG CCCCACTTGC TGCTCGTGTT GGTGCAGCTG |
The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.
CloneID | OMu12591 | |
Clone ID Related Accession (Same CDS sequence) | NM_022316.2 | |
Accession Version | NM_022316.2 Latest version! | Documents for ORF clone product in default vector |
Sequence Information | ORF Nucleotide Sequence (Length: 1359bp) Protein sequence SNP |
|
Vector | pcDNA3.1-C-(k)DYK or customized vector | ![]() |
Clone information | Clone Map | ![]() |
Tag on pcDNA3.1+/C-(K)DYK | C terminal DYKDDDDK tags | |
ORF Insert Method | CloneEZ™ Seamless cloning technology | |
Insert Structure | linear | |
Update Date | 2019-12-09 | |
Organism | Mus musculus(house mouse) | |
Product | SPARC-related modular calcium-binding protein 1 isoform 2 precursor | |
Comment | Comment: VALIDATED REFSEQ: This record has undergone validation or preliminary review. The reference sequence was derived from AK040931.1 and AC124384.4. On Apr 2, 2009 this sequence version replaced NM_022316.1. Transcript Variant: This variant (2) uses an alternate in-frame splice site in the coding region compared to variant 1. This results in a shorter protein (isoform 2) compared to isoform 1. Sequence Note: This RefSeq record was created from transcript and genomic sequence data to make the sequence consistent with the reference genome assembly. The genomic coordinates used for the transcript record were based on transcript alignments. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Gene record to access additional publications. ##Evidence-Data-START## Transcript exon combination :: BC031804.1, AF070470.1 [ECO:0000332] RNAseq introns :: single sample supports all introns SAMN00849374, SAMN00849375 [ECO:0000348] ##Evidence-Data-END## COMPLETENESS: complete on the 3' end. |
1 | ATGCTGCCCG CGCGCGTCCG TCTGCTCACG CCCCACTTGC TGCTCGTGTT GGTGCAGCTG |
The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.
RefSeq | NP_071711.2 |
CDS | 256..1614 |
Translation |
Target ORF information:
Target ORF information:
|
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1 | ATGCTGCCCG CGCGCGTCCG TCTGCTCACG CCCCACTTGC TGCTCGTGTT GGTGCAGCTG |
The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.
CloneID | OMu48034 | |
Clone ID Related Accession (Same CDS sequence) | XM_006516135.3 , XM_006516135.4 | |
Accession Version | XM_006516135.3 | Documents for ORF clone product in default vector |
Sequence Information | ORF Nucleotide Sequence (Length: 1371bp) Protein sequence SNP |
|
Vector | pcDNA3.1-C-(k)DYK or customized vector | ![]() |
Clone information | Clone Map | ![]() |
Tag on pcDNA3.1+/C-(K)DYK | C terminal DYKDDDDK tags | |
ORF Insert Method | CloneEZ™ Seamless cloning technology | |
Insert Structure | linear | |
Update Date | 2016-06-21 | |
Organism | Mus musculus(house mouse) | |
Product | SPARC-related modular calcium-binding protein 1 isoform X1 | |
Comment | Comment: MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_000078.6) annotated using gene prediction method: Gnomon, supported by mRNA and EST evidence. Also see: Documentation of NCBI's Annotation Process On Jun 22, 2016 this sequence version replaced XM_006516135.2. ##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Version :: Mus musculus Annotation Release 106 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 7.1 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END## |
1 | ATGAACAGCA GCAATACCAA GAGTGCTGGG ATTAAAGGCG TGCTCCACCA CTGTCCAGCA |
The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.
RefSeq | XP_006516198.1 |
CDS | 185..1555 |
Translation |
Target ORF information:
Target ORF information:
|
![]() |
1 | ATGAACAGCA GCAATACCAA GAGTGCTGGG ATTAAAGGCG TGCTCCACCA CTGTCCAGCA |
The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.
CloneID | OMu48034 | |
Clone ID Related Accession (Same CDS sequence) | XM_006516135.3 , XM_006516135.4 | |
Accession Version | XM_006516135.4 Latest version! | Documents for ORF clone product in default vector |
Sequence Information | ORF Nucleotide Sequence (Length: 1371bp) Protein sequence SNP |
|
Vector | pcDNA3.1-C-(k)DYK or customized vector | ![]() |
Clone information | Clone Map | ![]() |
Tag on pcDNA3.1+/C-(K)DYK | C terminal DYKDDDDK tags | |
ORF Insert Method | CloneEZ™ Seamless cloning technology | |
Insert Structure | linear | |
Update Date | 2019-08-07 | |
Organism | Mus musculus(house mouse) | |
Product | SPARC-related modular calcium-binding protein 1 isoform X1 | |
Comment | Comment: MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_000078.6) annotated using gene prediction method: Gnomon, supported by mRNA and EST evidence. Also see: Documentation of NCBI's Annotation Process On Aug 8, 2019 this sequence version replaced XM_006516135.3. ##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Name :: Mus musculus Annotation Release 108 Annotation Version :: 108 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 8.2 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END## |
1 | ATGAACAGCA GCAATACCAA GAGTGCTGGG ATTAAAGGCG TGCTCCACCA CTGTCCAGCA |
The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.
RefSeq | XP_006516198.1 |
CDS | 182..1552 |
Translation |
Target ORF information:
Target ORF information:
|
![]() |
1 | ATGAACAGCA GCAATACCAA GAGTGCTGGG ATTAAAGGCG TGCTCCACCA CTGTCCAGCA |
The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.
High-throughput discovery of novel developmental phenotypes. |
Pbx Regulates Patterning of the Cerebral Cortex in Progenitors and Postmitotic Neurons. |
Spatiotemporal regulation of GLI target genes in the mammalian limb bud. |