| Gene Symbol | Cubn |
| Entrez Gene ID | 65969 |
| Full Name | cubilin (intrinsic factor-cobalamin receptor) |
| Synonyms | AA408369,AL022750,D2Wsu88e |
| General protein information |
|
| Gene Type | protein-coding |
| Organism | Mus musculus(house mouse) |
| Genome |
gRNAs
The following Cubn gene cDNA ORF clone sequences were retrieved from the NCBI Reference Sequence Database (RefSeq). These sequences represent the protein coding region of the Cubn cDNA ORF which is encoded by the open reading frame (ORF) sequence. ORF sequences can be delivered in our standard vector, pcDNA3.1+/C-(K)DYK or the vector of your choice as an expression/transfection-ready ORF clone. Not the clone you want? Click here to find your clone.
| CloneID | OMu20964 | |
| Clone ID Related Accession (Same CDS sequence) | NM_001081084.2 | |
| Accession Version | NM_001081084.2 Latest version! | Documents for ORF clone product in default vector |
| Sequence Information | ORF Nucleotide Sequence (Length: 10872bp) Protein sequence SNP |
|
| Vector | pcDNA3.1-C-(k)DYK or customized vector |  User Manual |
| Clone information | Clone Map | MSDS |
| Tag on pcDNA3.1+/C-(K)DYK | C terminal DYKDDDDK tags | |
| ORF Insert Method | CloneEZ™ Seamless cloning technology | |
| Insert Structure | linear | |
| Update Date | 2019-09-15 | |
| Organism | Mus musculus(house mouse) | |
| Product | cubilin precursor | |
| Comment | Comment: VALIDATED REFSEQ: This record has undergone validation or preliminary review. The reference sequence was derived from AL773538.7, AK141391.1, CK623807.1, AL928807.3, CK390258.1, CK391977.1, CK391058.1, CF165743.1, CF169457.1, CK391475.1 and AF197159.1. On May 23, 2007 this sequence version replaced NM_001081084.1. Sequence Note: This RefSeq record was created from transcript and genomic sequence data because no single transcript from the same strain was available for the full length of the gene. The extent of this transcript is supported by orthologous data. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Gene record to access additional publications. ##Evidence-Data-START## RNAseq introns :: single sample supports all introns SAMN01164134 [ECO:0000348] ##Evidence-Data-END## | |
1 | ATGGCCTCAC ATTTTCTCTG GGGTTTTGTT ACTTTATTGA TGGTACCCGG ATTAGACGGT |
The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.
| RefSeq | NP_001074553.1 |
| CDS | 64..10935 |
| Translation |
Target ORF information:
Target ORF information:
|
 NM_001081084.2 |
1 | ATGGCCTCAC ATTTTCTCTG GGGTTTTGTT ACTTTATTGA TGGTACCCGG ATTAGACGGT |
The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.
Gene expression pattern in response to cholecalciferol supplementation highlights cubilin as a major protein of 25(OH)D uptake in adipocytes and male mice white adipose tissue. |
Reduced proximal tubular expression of protein endocytic receptors in proteinuria is associated with urinary receptor shedding. |
Megalin dependent urinary cystatin C excretion in ischemic kidney injury in rats. |
Loss of Zeb2 in mesenchyme-derived nephrons causes primary glomerulocystic disease. |
