Gene Symbol | Timm50 |
Entrez Gene ID | 66525 |
Full Name | translocase of inner mitochondrial membrane 50 |
Synonyms | 2810403L02Rik,AU015082,TIM50L |
General protein information |
|
Gene Type | protein-coding |
Organism | Mus musculus(house mouse) |
Genome |
ORF » Species Summary » Mus musculus » Timm50 cDNA ORF clone
Gene Symbol | Timm50 |
Entrez Gene ID | 66525 |
Full Name | translocase of inner mitochondrial membrane 50 |
Synonyms | 2810403L02Rik,AU015082,TIM50L |
General protein information |
|
Gene Type | protein-coding |
Organism | Mus musculus(house mouse) |
Genome |
mRNA | Protein | Name |
---|---|---|
XM_011250673.2 | XP_011248975.1 | mitochondrial import inner membrane translocase subunit TIM50 isoform X1 |
XM_011250673.3 | XP_011248975.1 | mitochondrial import inner membrane translocase subunit TIM50 isoform X1 |
NM_025616.3 | NP_079892.1 | mitochondrial import inner membrane translocase subunit TIM50 precursor |
Pan troglodytes (chimpanzee) | TIMM50 | XP_001138592.1 |
Bos taurus (cattle) | TIMM50 | NP_001030196.1 |
Mus musculus (house mouse) | Timm50 | NP_079892.1 |
Rattus norvegicus (Norway rat) | LOC687295 | XP_003748854.1 |
Xenopus tropicalis (tropical clawed frog) | timm50 | NP_001120038.1 |
Gallus gallus (chicken) | TIMM50 | XP_001233751.3 |
Danio rerio (zebrafish) | timm50 | NP_956959.1 |
Drosophila melanogaster (fruit fly) | ttm50 | NP_570027.1 |
Homo sapiens (human) | TIMM50 | NP_001001563.1 |
Canis lupus familiaris (dog) | TIMM50 | XP_533672.3 |
Anopheles gambiae (African malaria mosquito) | AgaP_AGAP001108 | XP_322056.5 |
Translocase of Inner Membrane 50 Functions as a Novel Protective Regulator of Pathological Cardiac Hypertrophy.
Tang K, Zhao Y, Li H, Zhu M, Li W, Liu W, Zhu G, Xu D, Peng W, Xu YW
Journal of the American Heart Association6(4)(2017 Apr)
High-throughput discovery of novel developmental phenotypes.
Dickinson ME, Flenniken AM, Ji X, Teboul L, Wong MD, White JK, Meehan TF, Weninger WJ, Westerberg H, Adissu H, Baker CN, Bower L, Brown JM, Caddle LB, Chiani F, Clary D, Cleak J, Daly MJ, Denegre JM, Doe B, Dolan ME, Edie SM, Fuchs H, Gailus-Durner V, Galli A, Gambadoro A, Gallegos J, Guo S, Horner NR, Hsu CW, Johnson SJ, Kalaga S, Keith LC, Lanoue L, Lawson TN, Lek M, Mark M, Marschall S, Mason J, McElwee ML, Newbigging S, Nutter LM, Peterson KA, Ramirez-Solis R, Rowland DJ, Ryder E, Samocha KE, Seavitt JR, Selloum M, Szoke-Kovacs Z, Tamura M, Trainor AG, Tudose I, Wakana S, Warren J, Wendling O, West DB, Wong L, Yoshiki A, , , , , , , , , MacArthur DG, Tocchini-Valentini GP, Gao X, Flicek P, Bradley A, Skarnes WC, Justice MJ, Parkinson HE, Moore M, Wells S, Braun RE, Svenson KL, de Angelis MH, Herault Y, Mohun T, Mallon AM, Henkelman RM, Brown SD, Adams DJ, Lloyd KC, McKerlie C, Beaudet AL, Bu?an M, Murray SA
Nature537(7621)508-514(2016 09)
Tim50, a component of the mitochondrial translocator, regulates mitochondrial integrity and cell death.
Guo Y, Cheong N, Zhang Z, De Rose R, Deng Y, Farber SA, Fernandes-Alnemri T, Alnemri ES
The Journal of biological chemistry279(23)24813-25(2004 Jun)
BayGenomics: a resource of insertional mutations in mouse embryonic stem cells.
Stryke D, Kawamoto M, Huang CC, Johns SJ, King LA, Harper CA, Meng EC, Lee RE, Yee A, L'Italien L, Chuang PT, Young SG, Skarnes WC, Babbitt PC, Ferrin TE
Nucleic acids research31(1)278-81(2003 Jan)
GeneRIFs: Gene References Into Functions What's a GeneRIF?
The following Timm50 gene cDNA ORF clone sequences were retrieved from the NCBI Reference Sequence Database (RefSeq). These sequences represent the protein coding region of the Timm50 cDNA ORF which is encoded by the open reading frame (ORF) sequence. ORF sequences can be delivered in our standard vector, pcDNA3.1+/C-(K)DYK or the vector of your choice as an expression/transfection-ready ORF clone. Not the clone you want? Click here to find your clone.
CloneID | OMu13400 | |
Clone ID Related Accession (Same CDS sequence) | NM_025616.3 | |
Accession Version | NM_025616.3 Latest version! | Documents for ORF clone product in default vector |
Sequence Information | ORF Nucleotide Sequence (Length: 1062bp) Protein sequence SNP |
|
Vector | pcDNA3.1-C-(k)DYK or customized vector | User Manual |
Clone information | Clone Map | MSDS |
Tag on pcDNA3.1+/C-(K)DYK | C terminal DYKDDDDK tags | |
ORF Insert Method | CloneEZ™ Seamless cloning technology | |
Insert Structure | linear | |
Update Date | 2019-09-20 | |
Organism | Mus musculus(house mouse) | |
Product | mitochondrial import inner membrane translocase subunit TIM50 precursor | |
Comment | Comment: PROVISIONAL REFSEQ: This record has not yet been subject to final NCBI review. The reference sequence was derived from AC148986.5. On Apr 29, 2007 this sequence version replaced NM_025616.2. Sequence Note: The RefSeq transcript and protein were derived from genomic sequence to make the sequence consistent with the reference genome assembly. The genomic coordinates used for the transcript record were based on alignments. ##Evidence-Data-START## Transcript exon combination :: AK008340.1, AK167473.1 [ECO:0000332] RNAseq introns :: single sample supports all introns SAMN01164138, SAMN01164139 [ECO:0000348] ##Evidence-Data-END## ##RefSeq-Attributes-START## gene product(s) localized to mito. :: reported by MitoCarta ##RefSeq-Attributes-END## |
1 | ATGGCGGCCT CGGCGGCTCT GTTCTCGCGC TTGCGGAGCG GGCTCCGGGT AGGCGCGCGG |
The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.
RefSeq | NP_079892.1 |
CDS | 15..1076 |
Translation |
Target ORF information:
Target ORF information:
|
NM_025616.3 |
1 | ATGGCGGCCT CGGCGGCTCT GTTCTCGCGC TTGCGGAGCG GGCTCCGGGT AGGCGCGCGG |
The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.
CloneID | OMu69958 | |
Clone ID Related Accession (Same CDS sequence) | XM_011250673.2 , XM_011250673.3 | |
Accession Version | XM_011250673.2 | Documents for ORF clone product in default vector |
Sequence Information | ORF Nucleotide Sequence (Length: 1119bp) Protein sequence SNP |
|
Vector | pcDNA3.1-C-(k)DYK or customized vector | User Manual |
Clone information | Clone Map | MSDS |
Tag on pcDNA3.1+/C-(K)DYK | C terminal DYKDDDDK tags | |
ORF Insert Method | CloneEZ™ Seamless cloning technology | |
Insert Structure | linear | |
Update Date | 2016-06-21 | |
Organism | Mus musculus(house mouse) | |
Product | mitochondrial import inner membrane translocase subunit TIM50 isoform X1 | |
Comment | Comment: MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_000073.6) annotated using gene prediction method: Gnomon, supported by mRNA and EST evidence. Also see: Documentation of NCBI's Annotation Process On Jun 22, 2016 this sequence version replaced XM_011250673.1. ##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Version :: Mus musculus Annotation Release 106 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 7.1 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END## |
1 | ATGGGACGGA GCCCGCGTTT TCGATGTTTC CATGCTTCCT GTGTGGACCA CAGTTGCTCC |
The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.
RefSeq | XP_011248975.1 |
CDS | 68..1186 |
Translation |
Target ORF information:
Target ORF information:
|
XM_011250673.2 |
1 | ATGGGACGGA GCCCGCGTTT TCGATGTTTC CATGCTTCCT GTGTGGACCA CAGTTGCTCC |
The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.
CloneID | OMu69958 | |
Clone ID Related Accession (Same CDS sequence) | XM_011250673.2 , XM_011250673.3 | |
Accession Version | XM_011250673.3 Latest version! | Documents for ORF clone product in default vector |
Sequence Information | ORF Nucleotide Sequence (Length: 1119bp) Protein sequence SNP |
|
Vector | pcDNA3.1-C-(k)DYK or customized vector | User Manual |
Clone information | Clone Map | MSDS |
Tag on pcDNA3.1+/C-(K)DYK | C terminal DYKDDDDK tags | |
ORF Insert Method | CloneEZ™ Seamless cloning technology | |
Insert Structure | linear | |
Update Date | 2019-08-07 | |
Organism | Mus musculus(house mouse) | |
Product | mitochondrial import inner membrane translocase subunit TIM50 isoform X1 | |
Comment | Comment: MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_000073.6) annotated using gene prediction method: Gnomon, supported by mRNA and EST evidence. Also see: Documentation of NCBI's Annotation Process On Aug 8, 2019 this sequence version replaced XM_011250673.2. ##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Name :: Mus musculus Annotation Release 108 Annotation Version :: 108 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 8.2 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END## |
1 | ATGGGACGGA GCCCGCGTTT TCGATGTTTC CATGCTTCCT GTGTGGACCA CAGTTGCTCC |
The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.
RefSeq | XP_011248975.1 |
CDS | 193..1311 |
Translation |
Target ORF information:
Target ORF information:
|
XM_011250673.3 |
1 | ATGGGACGGA GCCCGCGTTT TCGATGTTTC CATGCTTCCT GTGTGGACCA CAGTTGCTCC |
The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.
Translocase of Inner Membrane 50 Functions as a Novel Protective Regulator of Pathological Cardiac Hypertrophy. |
High-throughput discovery of novel developmental phenotypes. |
Tim50, a component of the mitochondrial translocator, regulates mitochondrial integrity and cell death. |
BayGenomics: a resource of insertional mutations in mouse embryonic stem cells. |