Ndufs3 cDNA ORF clone, Mus musculus(house mouse)

Gene
Clones
gRNAs

Gene Symbol	Ndufs3
Entrez Gene ID	68349
Full Name	NADH dehydrogenase (ubiquinone) Fe-S protein 3
Synonyms	0610010M09Rik,CI-30kD
General protein information	Preferred Names NADH dehydrogenase (ubiquinone) Fe-S protein 3 Names NADH dehydrogenase [ubiquinone] iron-sulfur protein 3, mitochondrial NADH-ubiquinone oxidoreductase 30 kDa subunit complex I-30kD
Gene Type	protein-coding
Organism	Mus musculus(house mouse)
Genome	Chromosome: 2 Map Location: 2\|2 E1

mRNA and Protein(s)

mRNA	Protein	Name
NM_026688.2	NP_080964.1	NADH dehydrogenase [ubiquinone] iron-sulfur protein 3, mitochondrial precursor
NM_026688.3	NP_080964.1	NADH dehydrogenase [ubiquinone] iron-sulfur protein 3, mitochondrial precursor

Pathways from BioSystems

Homologies

Homo sapiens (human)	NDUFS3	NP_004542.1
	NDUFS3	XP_001105264.1
Mus musculus (house mouse)	Ndufs3	NP_080964.1
Danio rerio (zebrafish)	ndufs3	NP_001017755.1
Caenorhabditis elegans (roundworm)	nuo-2	NP_491881.2
Arabidopsis thaliana (thale cress)	nad9	NP_085479.1
Canis lupus familiaris (dog)	NDUFS3	XP_533185.2
Rattus norvegicus (Norway rat)	Ndufs3	NP_001099959.1
Magnaporthe oryzae (rice blast fungus)	MGG_01333	XP_003714259.1
Neurospora crassa	NCU04074	XP_957689.1
Pan troglodytes (chimpanzee)	NDUFS3	NP_001073382.1
Bos taurus (cattle)	NDUFS3	NP_777244.1
Drosophila melanogaster (fruit fly)	CG12079	NP_647775.1
Gallus gallus (chicken)	NDUFS3	NP_001139804.1
Anopheles gambiae (African malaria mosquito)	AgaP_AGAP006456	XP_316497.2
Xenopus tropicalis (tropical clawed frog)	ndufs3	NP_001003921.1

Gene Ontology
Bibliography

Related articles in PubMed

Partial complex I deficiency due to the CNS conditional ablation of Ndufa5 results in a mild chronic encephalopathy but no increase in oxidative damage.
Peralta S, Torraco A, Wenz T, Garcia S, Diaz F, Moraes CT
Human molecular genetics23(6)1399-412(2014 Mar)

Region-specific expression of mitochondrial complex I genes during murine brain development.
Wirtz S, Schuelke M
PloS one6(4)e18897(2011 Apr)

Analysis of mouse models of cytochrome c oxidase deficiency owing to mutations in Sco2.
Yang H, Brosel S, Acin-Perez R, Slavkovich V, Nishino I, Khan R, Goldberg IJ, Graziano J, Manfredi G, Schon EA
Human molecular genetics19(1)170-80(2010 Jan)

Mice with mitochondrial complex I deficiency develop a fatal encephalomyopathy.
Kruse SE, Watt WC, Marcinek DJ, Kapur RP, Schenkman KA, Palmiter RD
Cell metabolism7(4)312-20(2008 Apr)

Proteolipid protein is required for transport of sirtuin 2 into CNS myelin.
Werner HB, Kuhlmann K, Shen S, Uecker M, Schardt A, Dimova K, Orfaniotou F, Dhaunchak A, Brinkmann BG, M?bius W, Guarente L, Casaccia-Bonnefil P, Jahn O, Nave KA
The Journal of neuroscience : the official journal of the Society for Neuroscience27(29)7717-30(2007 Jul)

GeneRIFs: Gene References Into Functions What's a GeneRIF?

The following Ndufs3 gene cDNA ORF clone sequences were retrieved from the NCBI Reference Sequence Database (RefSeq). These sequences represent the protein coding region of the Ndufs3 cDNA ORF which is encoded by the open reading frame (ORF) sequence. ORF sequences can be delivered in our standard vector, pcDNA3.1⁺/C-(K)DYK or the vector of your choice as an expression/transfection-ready ORF clone. Not the clone you want? Click here to find your clone.

***CloneID	Accession No.	Definition	**Vector	*Turnaround time	Price (USD)
OMu15116	NM_026688.3 Latest version!	Mus musculus NADH:ubiquinone oxidoreductase core subunit S3 (Ndufs3), mRNA.	pcDNA3.1-C-(k)DYK or customized vector	5-7	$188.30 $269.00
View Old Accession Versions >>
OMu15116	NM_026688.2	Mus musculus NADH dehydrogenase (ubiquinone) Fe-S protein 3 (Ndufs3), mRNA.	pcDNA3.1-C-(k)DYK or customized vector	5-7	$188.30 $269.00
Hide Old Accession Versions >>

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** GenScript guarantees 100% sequence accuracy of all synthetic DNA constructs we deliver, but we do not guarantee protein expression in your experimental system. Protein expression is influenced by many factors that may vary between experiments or laboratories. In addition, please pay attention to the signal peptide, propeptide and transit peptide in target ORF, which may affect the choice of vector (N/C terminal tag vector).

***One clone ID might be correlated to multiple accession numbers, which share the same CDS sequence.

Reference Sequences (Refseq)

Ndufs3 ( NM_026688.2 ) cDNA ORF clone, Mus musculus(house mouse) -> NP_080964.1 Mus musculus NADH dehydrogenase (ubiquinone) Fe-S protein 3 (Ndufs3), mRNA.

Price & Availability↑

CloneID	OMu15116
Clone ID Related Accession (Same CDS sequence)	NM_026688.2 , NM_026688.3
Accession Version	NM_026688.2	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 792bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2017-12-26
Organism	Mus musculus(house mouse)
Product	NADH dehydrogenase [ubiquinone] iron-sulfur protein 3, mitochondrial precursor
Comment	Comment: PROVISIONAL REFSEQ: This record has not yet been subject to final NCBI review. The reference sequence was derived from AK088337.1. On Apr 5, 2007 this sequence version replaced NM_026688.1. ##Evidence-Data-START## Transcript exon combination :: AK088337.1, AK002501.1 [ECO:0000332] RNAseq introns :: single sample supports all introns SAMN00849374, SAMN00849376 [ECO:0000348] ##Evidence-Data-END## ##RefSeq-Attributes-START## gene product(s) localized to mito. :: reported by MitoCarta ##RefSeq-Attributes-END##

ATGGCGGCGG CTGCAGCCAG GGTCTGGTGT CGTGGGCTCT TGGGGGCCGC TTCCGTAGGC 
AGGGGGGCTG GGCGACCCTC CGTGCTGTGG CAGCACGTAA GAAGGGAGAG CGCGGCGGCT 
GACAAGCGCC CCACTGTCAG ACCCCGGAGT GATGTGACCC ACAAGCAGCT CTCAGCATTT 
GGAGAGTATG TGGCTGAAAT CTTACCCAAG TATGTCCAAC AAGTTCAGGT GTCCTGCCTT 
GATGAGTTAG AAATCTGTAT CCATCCCGAT GGAGTCATCC CAACGCTGAC TTTTCTCAGG 
GATCACACCA ATGCACAATT CAAATCCTTG GCTGACTTGA CGGCAGTGGA TGTCCCAACT 
CGGCAGAACC GTTTTGAGAT TGTCTACAAC CTGCTGTCTC TGCGGTTCAA CTCTAGGATT 
CGTGTGAAGA CCTATGCAGA TGAGCTGACA CCCATTGACT CTATAGTGTC TGTGCACATC 
GCGGCCAATT GGTATGAGAG GGAGGTCTGG GACATGTTTG GAGTTTTCTT TTTTAACCAC 
CCTGATTTAA GAAGGATCCT GACAGATTAT GGCTTCGAGG GACATCCTTT CCGGAAAGAC 
TTTCCCCTCA CTGGCTATGT TGAGCTTCGT TACGACGATG AGGTAAAGCG GGTAGTGGCT 
GAACCAGTGG AGCTGGCACA AGAATTCCGC AAGTTTGACC TGAACAGCCC CTGGGAGGCT 
TTCCCTGCCT ATCGCCAGCC TCCTGAGAGT CTCAAGCTCG AAGCTGGAGA CAAGAAGCCT 
GAAACCAAGT AA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	NP_080964.1
CDS	75..866
Translation	MAAAAARVWCRGLLGAASVGRGAGRPSVLWQHVRRESAAADKRPTVRPRSDVTHKQLSAFGEYVAEILPKYVQQVQVSCLDELEICIHPDGVIPTLTFLRDHTNAQFKSLADLTAVDVPTRQNRFEIVYNLLSLRFNSRIRVKTYADELTPIDSIVSVHIAANWYEREVWDMFGVFFFNHPDLRRILTDYGFEGHPFRKDFPLTGYVELRYDDEVKRVVAEPVELAQEFRKFDLNSPWEAFPAYRQPPESLKLEAGDKKPETK

Target ORF information:

RefSeq Version	NM_026688.2
Organism	Mus musculus(house mouse)
Definition	Mus musculus NADH dehydrogenase (ubiquinone) Fe-S protein 3 (Ndufs3), mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

NM_026688.2

ORF Insert Sequence:

ATGGCGGCGG CTGCAGCCAG GGTCTGGTGT CGTGGGCTCT TGGGGGCCGC TTCCGTAGGC 
AGGGGGGCTG GGCGACCCTC CGTGCTGTGG CAGCACGTAA GAAGGGAGAG CGCGGCGGCT 
GACAAGCGCC CCACTGTCAG ACCCCGGAGT GATGTGACCC ACAAGCAGCT CTCAGCATTT 
GGAGAGTATG TGGCTGAAAT CTTACCCAAG TATGTCCAAC AAGTTCAGGT GTCCTGCCTT 
GATGAGTTAG AAATCTGTAT CCATCCCGAT GGAGTCATCC CAACGCTGAC TTTTCTCAGG 
GATCACACCA ATGCACAATT CAAATCCTTG GCTGACTTGA CGGCAGTGGA TGTCCCAACT 
CGGCAGAACC GTTTTGAGAT TGTCTACAAC CTGCTGTCTC TGCGGTTCAA CTCTAGGATT 
CGTGTGAAGA CCTATGCAGA TGAGCTGACA CCCATTGACT CTATAGTGTC TGTGCACATC 
GCGGCCAATT GGTATGAGAG GGAGGTCTGG GACATGTTTG GAGTTTTCTT TTTTAACCAC 
CCTGATTTAA GAAGGATCCT GACAGATTAT GGCTTCGAGG GACATCCTTT CCGGAAAGAC 
TTTCCCCTCA CTGGCTATGT TGAGCTTCGT TACGACGATG AGGTAAAGCG GGTAGTGGCT 
GAACCAGTGG AGCTGGCACA AGAATTCCGC AAGTTTGACC TGAACAGCCC CTGGGAGGCT 
TTCCCTGCCT ATCGCCAGCC TCCTGAGAGT CTCAAGCTCG AAGCTGGAGA CAAGAAGCCT 
GAAACCAAGT AA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

Ndufs3 ( NM_026688.3 ) cDNA ORF clone, Mus musculus(house mouse) -> NP_080964.1 Mus musculus NADH:ubiquinone oxidoreductase core subunit S3 (Ndufs3), mRNA.

Price & Availability↑

CloneID	OMu15116
Clone ID Related Accession (Same CDS sequence)	NM_026688.2 , NM_026688.3
Accession Version	NM_026688.3 Latest version!	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 792bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2019-07-05
Organism	Mus musculus(house mouse)
Product	NADH dehydrogenase [ubiquinone] iron-sulfur protein 3, mitochondrial precursor
Comment	Comment: VALIDATED REFSEQ: This record has undergone validation or preliminary review. The reference sequence was derived from AL672241.6. On Apr 25, 2018 this sequence version replaced NM_026688.2. ##Evidence-Data-START## Transcript exon combination :: AK088337.1, AK002501.1 [ECO:0000332] RNAseq introns :: single sample supports all introns SAMN00849374, SAMN00849376 [ECO:0000348] ##Evidence-Data-END## ##RefSeq-Attributes-START## gene product(s) localized to mito. :: reported by MitoCarta ##RefSeq-Attributes-END## COMPLETENESS: complete on the 3' end.

ATGGCGGCGG CTGCAGCCAG GGTCTGGTGT CGTGGGCTCT TGGGGGCCGC TTCCGTAGGC 
AGGGGGGCTG GGCGACCCTC CGTGCTGTGG CAGCACGTAA GAAGGGAGAG CGCGGCGGCT 
GACAAGCGCC CCACTGTCAG ACCCCGGAGT GATGTGACCC ACAAGCAGCT CTCAGCATTT 
GGAGAGTATG TGGCTGAAAT CTTACCCAAG TATGTCCAAC AAGTTCAGGT GTCCTGCCTT 
GATGAGTTAG AAATCTGTAT CCATCCCGAT GGAGTCATCC CAACGCTGAC TTTTCTCAGG 
GATCACACCA ATGCACAATT CAAATCCTTG GCTGACTTGA CGGCAGTGGA TGTCCCAACT 
CGGCAGAACC GTTTTGAGAT TGTCTACAAC CTGCTGTCTC TGCGGTTCAA CTCTAGGATT 
CGTGTGAAGA CCTATGCAGA TGAGCTGACA CCCATTGACT CTATAGTGTC TGTGCACATC 
GCGGCCAATT GGTATGAGAG GGAGGTCTGG GACATGTTTG GAGTTTTCTT TTTTAACCAC 
CCTGATTTAA GAAGGATCCT GACAGATTAT GGCTTCGAGG GACATCCTTT CCGGAAAGAC 
TTTCCCCTCA CTGGCTATGT TGAGCTTCGT TACGACGATG AGGTAAAGCG GGTAGTGGCT 
GAACCAGTGG AGCTGGCACA AGAATTCCGC AAGTTTGACC TGAACAGCCC CTGGGAGGCT 
TTCCCTGCCT ATCGCCAGCC TCCTGAGAGT CTCAAGCTCG AAGCTGGAGA CAAGAAGCCT 
GAAACCAAGT AA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	NP_080964.1
CDS	75..866
Translation	MAAAAARVWCRGLLGAASVGRGAGRPSVLWQHVRRESAAADKRPTVRPRSDVTHKQLSAFGEYVAEILPKYVQQVQVSCLDELEICIHPDGVIPTLTFLRDHTNAQFKSLADLTAVDVPTRQNRFEIVYNLLSLRFNSRIRVKTYADELTPIDSIVSVHIAANWYEREVWDMFGVFFFNHPDLRRILTDYGFEGHPFRKDFPLTGYVELRYDDEVKRVVAEPVELAQEFRKFDLNSPWEAFPAYRQPPESLKLEAGDKKPETK

Target ORF information:

RefSeq Version	NM_026688.3
Organism	Mus musculus(house mouse)
Definition	Mus musculus NADH:ubiquinone oxidoreductase core subunit S3 (Ndufs3), mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

NM_026688.3

ORF Insert Sequence:

ATGGCGGCGG CTGCAGCCAG GGTCTGGTGT CGTGGGCTCT TGGGGGCCGC TTCCGTAGGC 
AGGGGGGCTG GGCGACCCTC CGTGCTGTGG CAGCACGTAA GAAGGGAGAG CGCGGCGGCT 
GACAAGCGCC CCACTGTCAG ACCCCGGAGT GATGTGACCC ACAAGCAGCT CTCAGCATTT 
GGAGAGTATG TGGCTGAAAT CTTACCCAAG TATGTCCAAC AAGTTCAGGT GTCCTGCCTT 
GATGAGTTAG AAATCTGTAT CCATCCCGAT GGAGTCATCC CAACGCTGAC TTTTCTCAGG 
GATCACACCA ATGCACAATT CAAATCCTTG GCTGACTTGA CGGCAGTGGA TGTCCCAACT 
CGGCAGAACC GTTTTGAGAT TGTCTACAAC CTGCTGTCTC TGCGGTTCAA CTCTAGGATT 
CGTGTGAAGA CCTATGCAGA TGAGCTGACA CCCATTGACT CTATAGTGTC TGTGCACATC 
GCGGCCAATT GGTATGAGAG GGAGGTCTGG GACATGTTTG GAGTTTTCTT TTTTAACCAC 
CCTGATTTAA GAAGGATCCT GACAGATTAT GGCTTCGAGG GACATCCTTT CCGGAAAGAC 
TTTCCCCTCA CTGGCTATGT TGAGCTTCGT TACGACGATG AGGTAAAGCG GGTAGTGGCT 
GAACCAGTGG AGCTGGCACA AGAATTCCGC AAGTTTGACC TGAACAGCCC CTGGGAGGCT 
TTCCCTGCCT ATCGCCAGCC TCCTGAGAGT CTCAAGCTCG AAGCTGGAGA CAAGAAGCCT 
GAAACCAAGT AA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

PubMed

Partial complex I deficiency due to the CNS conditional ablation of Ndufa5 results in a mild chronic encephalopathy but no increase in oxidative damage.
Human molecular genetics23(6)1399-412(2014 Mar)
Peralta S,Torraco A,Wenz T,Garcia S,Diaz F,Moraes CT

Region-specific expression of mitochondrial complex I genes during murine brain development.
PloS one6(4)e18897(2011 Apr)
Wirtz S,Schuelke M

Analysis of mouse models of cytochrome c oxidase deficiency owing to mutations in Sco2.
Human molecular genetics19(1)170-80(2010 Jan)
Yang H,Brosel S,Acin-Perez R,Slavkovich V,Nishino I,Khan R,Goldberg IJ,Graziano J,Manfredi G,Schon EA

Mice with mitochondrial complex I deficiency develop a fatal encephalomyopathy.
Cell metabolism7(4)312-20(2008 Apr)
Kruse SE,Watt WC,Marcinek DJ,Kapur RP,Schenkman KA,Palmiter RD

Proteolipid protein is required for transport of sirtuin 2 into CNS myelin.
The Journal of neuroscience : the official journal of the Society for Neuroscience27(29)7717-30(2007 Jul)
Werner HB,Kuhlmann K,Shen S,Uecker M,Schardt A,Dimova K,Orfaniotou F,Dhaunchak A,Brinkmann BG,M?bius W,Guarente L,Casaccia-Bonnefil P,Jahn O,Nave KA

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Ndufs3 cDNA ORF clone, Mus musculus(house mouse)

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Related articles in PubMed

Target ORF information:

Target ORF information:

ORF Insert Sequence:

Target ORF information:

Target ORF information:

ORF Insert Sequence:

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