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Chmp2a cDNA ORF clone, Mus musculus(house mouse)

Summary

Gene Symbol Chmp2a
Entrez Gene ID 68953
Full Name charged multivesicular body protein 2A
Synonyms 1500016L11Rik
General protein information
Preferred Names

charged multivesicular body protein 2A

Names

charged multivesicular body protein 2a
chromatin modifying protein 2A
chromatin-modifying protein 2a
mVps2
vacuolar protein sorting-associated protein 2
Gene Type protein-coding
Organism Mus musculus(house mouse)
Genome

7

7 A1|7

Reference Sequences (RefSeq)

mRNA and Protein(s)

mRNA Protein Name
XM_006540345.2 XP_006540408.1 charged multivesicular body protein 2a isoform X1
NM_001360730.1 NP_001347659.1 charged multivesicular body protein 2a isoform a
XM_006540345.3 XP_006540408.1 charged multivesicular body protein 2a isoform X2
NM_026885.3 NP_081161.1 charged multivesicular body protein 2a isoform a
NM_001360733.1 NP_001347662.1 charged multivesicular body protein 2a isoform c
XM_006540344.1 XP_006540407.1 charged multivesicular body protein 2a isoform X1
XM_011250690.1 XP_011248992.1 charged multivesicular body protein 2a isoform X1
NM_001360731.1 NP_001347660.1 charged multivesicular body protein 2a isoform b

Pathways from BioSystems


Homologies


Xenopus tropicalis (tropical clawed frog) chmp2a NP_001005008.1
Homo sapiens (human) CHMP2A NP_940818.1
Canis lupus familiaris (dog) CHMP2A XP_850536.1
Anopheles gambiae (African malaria mosquito) AgaP_AGAP001285 XP_321862.3
Caenorhabditis elegans (roundworm) vps-2 NP_496717.1
Schizosaccharomyces pombe (fission yeast) did4 NP_593871.3
Oryza sativa (rice) Os07g0236800 NP_001059248.1
Bos taurus (cattle) CHMP2A NP_001029722.1
Mus musculus (house mouse) Chmp2a NP_081161.1
Rattus norvegicus (Norway rat) Chmp2a NP_001102376.1
Danio rerio (zebrafish) bc2 NP_998682.1
Neurospora crassa NCU00435 XP_956699.1
Pan troglodytes (chimpanzee) CHMP2A XP_003316813.1
CHMP2A XP_001099219.1
Gallus gallus (chicken) CHMP2A NP_001074361.1
Drosophila melanogaster (fruit fly) vps2 NP_651455.1
Magnaporthe oryzae (rice blast fungus) MGG_05208 XP_003712753.1
Saccharomyces cerevisiae (baker's yeast) DID4 NP_012924.2
Kluyveromyces lactis KLLA0B13343g XP_452125.1
Eremothecium gossypii AGOS_ABR002C NP_982948.1
Arabidopsis thaliana (thale cress) VPS2.1 NP_565336.1

Gene Ontology


Bibliography

Related articles in PubMed

Germline Chd8 haploinsufficiency alters brain development in mouse.
Gompers AL, Su-Feher L, Ellegood J, Copping NA, Riyadh MA, Stradleigh TW, Pride MC, Schaffler MD, Wade AA, Catta-Preta R, Zdilar I, Louis S, Kaushik G, Mannion BJ, Plajzer-Frick I, Afzal V, Visel A, Pennacchio LA, Dickel DE, Lerch JP, Crawley JN, Zarbalis KS, Silverman JL, Nord AS
Nature neuroscience20(8)1062-1073(2017 Aug)

Mammalian class E Vps proteins, SBP1 and mVps2/CHMP2A, interact with and regulate the function of an AAA-ATPase SKD1/Vps4B.
Fujita H, Umezuki Y, Imamura K, Ishikawa D, Uchimura S, Nara A, Yoshimori T, Hayashizaki Y, Kawai J, Ishidoh K, Tanaka Y, Himeno M
Journal of cell science117(Pt 14)2997-3009(2004 Jun)

GeneRIFs: Gene References Into Functions What's a GeneRIF?

The following Chmp2a gene cDNA ORF clone sequences were retrieved from the NCBI Reference Sequence Database (RefSeq). These sequences represent the protein coding region of the Chmp2a cDNA ORF which is encoded by the open reading frame (ORF) sequence. ORF sequences can be delivered in our standard vector, pcDNA3.1+/C-(K)DYK or the vector of your choice as an expression/transfection-ready ORF clone. Not the clone you want? Click here to find your clone.

***CloneID Accession No. Definition **Vector *Turnaround time Price (USD) Select
OMu38489 XM_006540344.1
Latest version!		 Mus musculus charged multivesicular body protein 2A (Chmp2a), transcript variant X1, mRNA. pcDNA3.1+/C-(K)DYK or customized vector 7-9 $139.30
$199.00
OMu38489 XM_011250690.1
Latest version!		 Mus musculus charged multivesicular body protein 2A (Chmp2a), transcript variant X2, mRNA. pcDNA3.1+/C-(K)DYK or customized vector 7-9 $139.30
$199.00
OMu03216 NM_026885.3
Latest version!		 Mus musculus charged multivesicular body protein 2A (Chmp2a), transcript variant 2, mRNA. pcDNA3.1+/C-(K)DYK or customized vector 5-7 $139.30
$199.00
OMu03216 NM_001360730.1
Latest version!		 Mus musculus charged multivesicular body protein 2A (Chmp2a), transcript variant 1, mRNA. pcDNA3.1+/C-(K)DYK or customized vector 5-7 $139.30
$199.00
OMu84018 NM_001360733.1
Latest version!		 Mus musculus charged multivesicular body protein 2A (Chmp2a), transcript variant 4, mRNA. pcDNA3.1+/C-(K)DYK or customized vector 9-11 $69.30
$99.00
OMu84328 NM_001360731.1
Latest version!		 Mus musculus charged multivesicular body protein 2A (Chmp2a), transcript variant 3, mRNA. pcDNA3.1+/C-(K)DYK or customized vector 9-11 $69.30
$99.00
OMu03216 XM_006540345.3
Latest version!		 Mus musculus charged multivesicular body protein 2A (Chmp2a), transcript variant X3, mRNA. pcDNA3.1+/C-(K)DYK or customized vector 5-7 $139.30
$199.00
View Old Accession Versions >>
OMu03216 XM_006540345.2 Mus musculus charged multivesicular body protein 2A (Chmp2a), transcript variant X3, mRNA. pcDNA3.1+/C-(K)DYK or customized vector 5-7 $139.30
$199.00
Hide Old Accession Versions >>

ORF Online Only Promotion

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** You may select a custom vector to replace pcDNA3.1+/C-(K)DYK after clone is added to cart.

** GenScript guarantees 100% sequence accuracy of all synthetic DNA constructs we deliver, but we do not guarantee protein expression in your experimental system. Protein expression is influenced by many factors that may vary between experiments or laboratories. In addition, please pay attention to the signal peptide, propeptide and transit peptide in target ORF, which may affect the choice of vector (N/C terminal tag vector).

***One clone ID might be correlated to multiple accession numbers, which share the same CDS sequence.

Reference Sequences (Refseq)


CloneID OMu38489
Clone ID Related Accession (Same CDS sequence) XM_006540344.1 , XM_011250690.1
Accession Version XM_006540344.1 Latest version! Documents for ORF clone product in default vector
Sequence Information ORF Nucleotide Sequence (Length: 753bp)
Protein sequence
SNP
Vector pcDNA3.1+/C-(K)DYK or customized vector User Manual
Clone information Clone Map MSDS
Tag on pcDNA3.1+/C-(K)DYK C terminal DYKDDDDK tags
ORF Insert Method CloneEZ™ Seamless cloning technology
Insert Structure linear
Update Date 2016-06-21
Organism Mus musculus(house mouse)
Product charged multivesicular body protein 2a isoform X1
Comment Comment: MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_000073.6) annotated using gene prediction method: Gnomon, supported by EST evidence. Also see: Documentation of NCBI's Annotation Process ##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Version :: Mus musculus Annotation Release 106 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 7.1 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END## 

1
61
121
181
241
301
361
421
481
541
601
661
721
ATGGACCTGT TGTTTGGGCG CCGGAAGACG CCAGAGGAAC TACTTCGGCA AAACCAGAGG 
GCCCTGAACC GAGCCATGAG AGAACTGGAC AGGGAACGAC AGAAACTAGA AACCCAGGAA 
AAGAAAATCA TTGCGGACAT CAAAAAGATG GCAAAGCAAG GCCAGATGGA TGCTGTTCGA 
ATCATGGCAA AAGACCTGGT GCGTACCCGG AGATATGTAC GCAAGTTTGT GTTGATGCGG 
GCCAACATCC AAGCTGTGTC CCTCAAGATA CAGACTCTAA AATCCAACAA CTCAATGGCA 
CAAGCCATGA AGGGTGTTAC TAAGGCCATG GGCACTATGA ACAGACAGCT GAAATTACCC 
CAGATCCAGA AGATCATGAT GGAGTTTGAA CGGCAGGCAG AGATCATGGA CATGAAGGAA 
GAAATGATGA ATGACGCAAT TGATGATGCC ATGGGTGATG AGGAAGATGA AGAGGAGAGG 
TGTGAGACTT TGACAGGAAG GCAGGGATAT TTACCAGGAC CCTTACCCAT TCGTAGTCCT 
GATGAGTTCT TTTTCTTTCC TAGTGATGCT GTTGTGTCCC AGGTCCTGGA TGAGCTGGGA 
CTGAGCCTCA CAGATGAGCT GTCAAACCTT CCCTCCACTG GAGGCTCACT CAGTGTGGCA 
GCTGGTGGGA AGAAAGCAGA GGCCACAGCC TCAGCCCTGG CTGATGCTGA TGCAGACCTG 
GAAGAGAGGC TCAAGAACCT TCGCAGGGAC TGA

The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.

RefSeq XP_006540407.1
CDS165..917
Translation

Target ORF information:

RefSeq Version XM_006540344.1
Organism Mus musculus(house mouse)
Definition Mus musculus charged multivesicular body protein 2A (Chmp2a), transcript variant X1, mRNA.

Target ORF information:

Epitope DYKDDDDK
Bacterial selection AMPR
Mammalian selection NeoR
Vector pcDNA3.1+/C-(K)DYK
 XM_006540344.1

ORF Insert Sequence:

1
61
121
181
241
301
361
421
481
541
601
661
721
ATGGACCTGT TGTTTGGGCG CCGGAAGACG CCAGAGGAAC TACTTCGGCA AAACCAGAGG 
GCCCTGAACC GAGCCATGAG AGAACTGGAC AGGGAACGAC AGAAACTAGA AACCCAGGAA 
AAGAAAATCA TTGCGGACAT CAAAAAGATG GCAAAGCAAG GCCAGATGGA TGCTGTTCGA 
ATCATGGCAA AAGACCTGGT GCGTACCCGG AGATATGTAC GCAAGTTTGT GTTGATGCGG 
GCCAACATCC AAGCTGTGTC CCTCAAGATA CAGACTCTAA AATCCAACAA CTCAATGGCA 
CAAGCCATGA AGGGTGTTAC TAAGGCCATG GGCACTATGA ACAGACAGCT GAAATTACCC 
CAGATCCAGA AGATCATGAT GGAGTTTGAA CGGCAGGCAG AGATCATGGA CATGAAGGAA 
GAAATGATGA ATGACGCAAT TGATGATGCC ATGGGTGATG AGGAAGATGA AGAGGAGAGG 
TGTGAGACTT TGACAGGAAG GCAGGGATAT TTACCAGGAC CCTTACCCAT TCGTAGTCCT 
GATGAGTTCT TTTTCTTTCC TAGTGATGCT GTTGTGTCCC AGGTCCTGGA TGAGCTGGGA 
CTGAGCCTCA CAGATGAGCT GTCAAACCTT CCCTCCACTG GAGGCTCACT CAGTGTGGCA 
GCTGGTGGGA AGAAAGCAGA GGCCACAGCC TCAGCCCTGG CTGATGCTGA TGCAGACCTG 
GAAGAGAGGC TCAAGAACCT TCGCAGGGAC TGA

The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.

CloneID OMu38489
Clone ID Related Accession (Same CDS sequence) XM_006540344.1 , XM_011250690.1
Accession Version XM_011250690.1 Latest version! Documents for ORF clone product in default vector
Sequence Information ORF Nucleotide Sequence (Length: 753bp)
Protein sequence
SNP
Vector pcDNA3.1+/C-(K)DYK or customized vector User Manual
Clone information Clone Map MSDS
Tag on pcDNA3.1+/C-(K)DYK C terminal DYKDDDDK tags
ORF Insert Method CloneEZ™ Seamless cloning technology
Insert Structure linear
Update Date 2016-06-21
Organism Mus musculus(house mouse)
Product charged multivesicular body protein 2a isoform X1
Comment Comment: MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_000073.6) annotated using gene prediction method: Gnomon, supported by EST evidence. Also see: Documentation of NCBI's Annotation Process ##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Version :: Mus musculus Annotation Release 106 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 7.1 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END## 

1
61
121
181
241
301
361
421
481
541
601
661
721
ATGGACCTGT TGTTTGGGCG CCGGAAGACG CCAGAGGAAC TACTTCGGCA AAACCAGAGG 
GCCCTGAACC GAGCCATGAG AGAACTGGAC AGGGAACGAC AGAAACTAGA AACCCAGGAA 
AAGAAAATCA TTGCGGACAT CAAAAAGATG GCAAAGCAAG GCCAGATGGA TGCTGTTCGA 
ATCATGGCAA AAGACCTGGT GCGTACCCGG AGATATGTAC GCAAGTTTGT GTTGATGCGG 
GCCAACATCC AAGCTGTGTC CCTCAAGATA CAGACTCTAA AATCCAACAA CTCAATGGCA 
CAAGCCATGA AGGGTGTTAC TAAGGCCATG GGCACTATGA ACAGACAGCT GAAATTACCC 
CAGATCCAGA AGATCATGAT GGAGTTTGAA CGGCAGGCAG AGATCATGGA CATGAAGGAA 
GAAATGATGA ATGACGCAAT TGATGATGCC ATGGGTGATG AGGAAGATGA AGAGGAGAGG 
TGTGAGACTT TGACAGGAAG GCAGGGATAT TTACCAGGAC CCTTACCCAT TCGTAGTCCT 
GATGAGTTCT TTTTCTTTCC TAGTGATGCT GTTGTGTCCC AGGTCCTGGA TGAGCTGGGA 
CTGAGCCTCA CAGATGAGCT GTCAAACCTT CCCTCCACTG GAGGCTCACT CAGTGTGGCA 
GCTGGTGGGA AGAAAGCAGA GGCCACAGCC TCAGCCCTGG CTGATGCTGA TGCAGACCTG 
GAAGAGAGGC TCAAGAACCT TCGCAGGGAC TGA

The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.

RefSeq XP_011248992.1
CDS195..947
Translation

Target ORF information:

RefSeq Version XM_011250690.1
Organism Mus musculus(house mouse)
Definition Mus musculus charged multivesicular body protein 2A (Chmp2a), transcript variant X2, mRNA.

Target ORF information:

Epitope DYKDDDDK
Bacterial selection AMPR
Mammalian selection NeoR
Vector pcDNA3.1+/C-(K)DYK
 XM_011250690.1

ORF Insert Sequence:

1
61
121
181
241
301
361
421
481
541
601
661
721
ATGGACCTGT TGTTTGGGCG CCGGAAGACG CCAGAGGAAC TACTTCGGCA AAACCAGAGG 
GCCCTGAACC GAGCCATGAG AGAACTGGAC AGGGAACGAC AGAAACTAGA AACCCAGGAA 
AAGAAAATCA TTGCGGACAT CAAAAAGATG GCAAAGCAAG GCCAGATGGA TGCTGTTCGA 
ATCATGGCAA AAGACCTGGT GCGTACCCGG AGATATGTAC GCAAGTTTGT GTTGATGCGG 
GCCAACATCC AAGCTGTGTC CCTCAAGATA CAGACTCTAA AATCCAACAA CTCAATGGCA 
CAAGCCATGA AGGGTGTTAC TAAGGCCATG GGCACTATGA ACAGACAGCT GAAATTACCC 
CAGATCCAGA AGATCATGAT GGAGTTTGAA CGGCAGGCAG AGATCATGGA CATGAAGGAA 
GAAATGATGA ATGACGCAAT TGATGATGCC ATGGGTGATG AGGAAGATGA AGAGGAGAGG 
TGTGAGACTT TGACAGGAAG GCAGGGATAT TTACCAGGAC CCTTACCCAT TCGTAGTCCT 
GATGAGTTCT TTTTCTTTCC TAGTGATGCT GTTGTGTCCC AGGTCCTGGA TGAGCTGGGA 
CTGAGCCTCA CAGATGAGCT GTCAAACCTT CCCTCCACTG GAGGCTCACT CAGTGTGGCA 
GCTGGTGGGA AGAAAGCAGA GGCCACAGCC TCAGCCCTGG CTGATGCTGA TGCAGACCTG 
GAAGAGAGGC TCAAGAACCT TCGCAGGGAC TGA

The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.

CloneID OMu03216
Clone ID Related Accession (Same CDS sequence) XM_006540345.2 , NM_001360730.1 , XM_006540345.3 , NM_026885.3
Accession Version NM_001360730.1 Latest version! Documents for ORF clone product in default vector
Sequence Information ORF Nucleotide Sequence (Length: 669bp)
Protein sequence
SNP
Vector pcDNA3.1+/C-(K)DYK or customized vector User Manual
Clone information Clone Map MSDS
Tag on pcDNA3.1+/C-(K)DYK C terminal DYKDDDDK tags
ORF Insert Method CloneEZ™ Seamless cloning technology
Insert Structure linear
Update Date 2019-10-23
Organism Mus musculus(house mouse)
Product charged multivesicular body protein 2a isoform a
Comment Comment: VALIDATED REFSEQ: This record has undergone validation or preliminary review. The reference sequence was derived from AC121301.8. On Feb 10, 2018 this sequence version replaced XM_006540345.3. Transcript Variant: This variant (1) represents the longest transcript and encodes the longest isoform (a). Variants 1 and 2 both encode the same isoform (a). Sequence Note: The RefSeq transcript and protein were derived from genomic sequence to make the sequence consistent with the reference genome assembly. The genomic coordinates used for the transcript record were based on alignments. ##Evidence-Data-START## Transcript exon combination :: BI413447.1, BU937207.1 [ECO:0000332] RNAseq introns :: single sample supports all introns SAMN01164134, SAMN01164135 [ECO:0000348] ##Evidence-Data-END## COMPLETENESS: complete on the 3' end. 

1
61
121
181
241
301
361
421
481
541
601
661
ATGGACCTGT TGTTTGGGCG CCGGAAGACG CCAGAGGAAC TACTTCGGCA AAACCAGAGG 
GCCCTGAACC GAGCCATGAG AGAACTGGAC AGGGAACGAC AGAAACTAGA AACCCAGGAA 
AAGAAAATCA TTGCGGACAT CAAAAAGATG GCAAAGCAAG GCCAGATGGA TGCTGTTCGA 
ATCATGGCAA AAGACCTGGT GCGTACCCGG AGATATGTAC GCAAGTTTGT GTTGATGCGG 
GCCAACATCC AAGCTGTGTC CCTCAAGATA CAGACTCTAA AATCCAACAA CTCAATGGCA 
CAAGCCATGA AGGGTGTTAC TAAGGCCATG GGCACTATGA ACAGACAGCT GAAATTACCC 
CAGATCCAGA AGATCATGAT GGAGTTTGAA CGGCAGGCAG AGATCATGGA CATGAAGGAA 
GAAATGATGA ATGACGCAAT TGATGATGCC ATGGGTGATG AGGAAGATGA AGAGGAGAGT 
GATGCTGTTG TGTCCCAGGT CCTGGATGAG CTGGGACTGA GCCTCACAGA TGAGCTGTCA 
AACCTTCCCT CCACTGGAGG CTCACTCAGT GTGGCAGCTG GTGGGAAGAA AGCAGAGGCC 
ACAGCCTCAG CCCTGGCTGA TGCTGATGCA GACCTGGAAG AGAGGCTCAA GAACCTTCGC 
AGGGACTGA

The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.

RefSeq NP_001347659.1
CDS323..991
Translation

Target ORF information:

RefSeq Version NM_001360730.1
Organism Mus musculus(house mouse)
Definition Mus musculus charged multivesicular body protein 2A (Chmp2a), transcript variant 1, mRNA.

Target ORF information:

Epitope DYKDDDDK
Bacterial selection AMPR
Mammalian selection NeoR
Vector pcDNA3.1+/C-(K)DYK
 NM_001360730.1

ORF Insert Sequence:

1
61
121
181
241
301
361
421
481
541
601
661
ATGGACCTGT TGTTTGGGCG CCGGAAGACG CCAGAGGAAC TACTTCGGCA AAACCAGAGG 
GCCCTGAACC GAGCCATGAG AGAACTGGAC AGGGAACGAC AGAAACTAGA AACCCAGGAA 
AAGAAAATCA TTGCGGACAT CAAAAAGATG GCAAAGCAAG GCCAGATGGA TGCTGTTCGA 
ATCATGGCAA AAGACCTGGT GCGTACCCGG AGATATGTAC GCAAGTTTGT GTTGATGCGG 
GCCAACATCC AAGCTGTGTC CCTCAAGATA CAGACTCTAA AATCCAACAA CTCAATGGCA 
CAAGCCATGA AGGGTGTTAC TAAGGCCATG GGCACTATGA ACAGACAGCT GAAATTACCC 
CAGATCCAGA AGATCATGAT GGAGTTTGAA CGGCAGGCAG AGATCATGGA CATGAAGGAA 
GAAATGATGA ATGACGCAAT TGATGATGCC ATGGGTGATG AGGAAGATGA AGAGGAGAGT 
GATGCTGTTG TGTCCCAGGT CCTGGATGAG CTGGGACTGA GCCTCACAGA TGAGCTGTCA 
AACCTTCCCT CCACTGGAGG CTCACTCAGT GTGGCAGCTG GTGGGAAGAA AGCAGAGGCC 
ACAGCCTCAG CCCTGGCTGA TGCTGATGCA GACCTGGAAG AGAGGCTCAA GAACCTTCGC 
AGGGACTGA

The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.

CloneID OMu03216
Clone ID Related Accession (Same CDS sequence) XM_006540345.2 , NM_001360730.1 , XM_006540345.3 , NM_026885.3
Accession Version NM_026885.3 Latest version! Documents for ORF clone product in default vector
Sequence Information ORF Nucleotide Sequence (Length: 669bp)
Protein sequence
SNP
Vector pcDNA3.1+/C-(K)DYK or customized vector User Manual
Clone information Clone Map MSDS
Tag on pcDNA3.1+/C-(K)DYK C terminal DYKDDDDK tags
ORF Insert Method CloneEZ™ Seamless cloning technology
Insert Structure linear
Update Date 2019-02-22
Organism Mus musculus(house mouse)
Product charged multivesicular body protein 2a isoform a
Comment Comment: VALIDATED REFSEQ: This record has undergone validation or preliminary review. The reference sequence was derived from BY157363.1, AK005267.1 and AC121301.8. On Jul 29, 2009 this sequence version replaced NM_026885.2. Transcript Variant: This variant (2) differs in the 5' UTR compared to variant 1. Variants 1 and 2 both encode the same isoform (a). ##Evidence-Data-START## Transcript exon combination :: DV047492.1, AK005267.1 [ECO:0000332] RNAseq introns :: single sample supports all introns SAMN00849377, SAMN00849381 [ECO:0000348] ##Evidence-Data-END## COMPLETENESS: complete on the 3' end. 

1
61
121
181
241
301
361
421
481
541
601
661
ATGGACCTGT TGTTTGGGCG CCGGAAGACG CCAGAGGAAC TACTTCGGCA AAACCAGAGG 
GCCCTGAACC GAGCCATGAG AGAACTGGAC AGGGAACGAC AGAAACTAGA AACCCAGGAA 
AAGAAAATCA TTGCGGACAT CAAAAAGATG GCAAAGCAAG GCCAGATGGA TGCTGTTCGA 
ATCATGGCAA AAGACCTGGT GCGTACCCGG AGATATGTAC GCAAGTTTGT GTTGATGCGG 
GCCAACATCC AAGCTGTGTC CCTCAAGATA CAGACTCTAA AATCCAACAA CTCAATGGCA 
CAAGCCATGA AGGGTGTTAC TAAGGCCATG GGCACTATGA ACAGACAGCT GAAATTACCC 
CAGATCCAGA AGATCATGAT GGAGTTTGAA CGGCAGGCAG AGATCATGGA CATGAAGGAA 
GAAATGATGA ATGACGCAAT TGATGATGCC ATGGGTGATG AGGAAGATGA AGAGGAGAGT 
GATGCTGTTG TGTCCCAGGT CCTGGATGAG CTGGGACTGA GCCTCACAGA TGAGCTGTCA 
AACCTTCCCT CCACTGGAGG CTCACTCAGT GTGGCAGCTG GTGGGAAGAA AGCAGAGGCC 
ACAGCCTCAG CCCTGGCTGA TGCTGATGCA GACCTGGAAG AGAGGCTCAA GAACCTTCGC 
AGGGACTGA

The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.

RefSeq NP_081161.1
CDS190..858
Translation

Target ORF information:

RefSeq Version NM_026885.3
Organism Mus musculus(house mouse)
Definition Mus musculus charged multivesicular body protein 2A (Chmp2a), transcript variant 2, mRNA.

Target ORF information:

Epitope DYKDDDDK
Bacterial selection AMPR
Mammalian selection NeoR
Vector pcDNA3.1+/C-(K)DYK
 NM_026885.3

ORF Insert Sequence:

1
61
121
181
241
301
361
421
481
541
601
661
ATGGACCTGT TGTTTGGGCG CCGGAAGACG CCAGAGGAAC TACTTCGGCA AAACCAGAGG 
GCCCTGAACC GAGCCATGAG AGAACTGGAC AGGGAACGAC AGAAACTAGA AACCCAGGAA 
AAGAAAATCA TTGCGGACAT CAAAAAGATG GCAAAGCAAG GCCAGATGGA TGCTGTTCGA 
ATCATGGCAA AAGACCTGGT GCGTACCCGG AGATATGTAC GCAAGTTTGT GTTGATGCGG 
GCCAACATCC AAGCTGTGTC CCTCAAGATA CAGACTCTAA AATCCAACAA CTCAATGGCA 
CAAGCCATGA AGGGTGTTAC TAAGGCCATG GGCACTATGA ACAGACAGCT GAAATTACCC 
CAGATCCAGA AGATCATGAT GGAGTTTGAA CGGCAGGCAG AGATCATGGA CATGAAGGAA 
GAAATGATGA ATGACGCAAT TGATGATGCC ATGGGTGATG AGGAAGATGA AGAGGAGAGT 
GATGCTGTTG TGTCCCAGGT CCTGGATGAG CTGGGACTGA GCCTCACAGA TGAGCTGTCA 
AACCTTCCCT CCACTGGAGG CTCACTCAGT GTGGCAGCTG GTGGGAAGAA AGCAGAGGCC 
ACAGCCTCAG CCCTGGCTGA TGCTGATGCA GACCTGGAAG AGAGGCTCAA GAACCTTCGC 
AGGGACTGA

The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.

CloneID OMu84018
Clone ID Related Accession (Same CDS sequence) NM_001360733.1
Accession Version NM_001360733.1 Latest version! Documents for ORF clone product in default vector
Sequence Information ORF Nucleotide Sequence (Length: 519bp)
Protein sequence
SNP
Vector pcDNA3.1+/C-(K)DYK or customized vector User Manual
Clone information Clone Map MSDS
Tag on pcDNA3.1+/C-(K)DYK C terminal DYKDDDDK tags
ORF Insert Method CloneEZ™ Seamless cloning technology
Insert Structure linear
Update Date 2019-10-24
Organism Mus musculus(house mouse)
Product charged multivesicular body protein 2a isoform c
Comment Comment: VALIDATED REFSEQ: This record has undergone validation or preliminary review. The reference sequence was derived from AC121301.8. Transcript Variant: This variant (4) differs in the 5' UTR and uses an alternate in-frame splice junction compared to variant 1. The resulting isoform (c) has the same N- and C-termini but is shorter compared to isoform a. Sequence Note: The RefSeq transcript and protein were derived from genomic sequence to make the sequence consistent with the reference genome assembly. The genomic coordinates used for the transcript record were based on alignments. ##Evidence-Data-START## Transcript exon combination :: CF423548.1, CK382658.1 [ECO:0000332] RNAseq introns :: single sample supports all introns SAMN00849383 [ECO:0000348] ##Evidence-Data-END## COMPLETENESS: complete on the 3' end. 

1
61
121
181
241
301
361
421
481
ATGGACCTGT TGTTTGGGCG CCGGAAGACG CCAGAGGAAC TACTTCGGCA AAACCAGAGG 
GCCCTGAACC GAGCCATGAG AGAACTGGAC AGGGAACGAC AGAAACTAGA AACCCAGGAA 
AAGAAAATCA TTGCGGACAT CAAAAAGATG GCAAAGCAAG GCCAGATGGA TGCTGTTCGA 
ATCATGGCAA AAGACCTGCT GAAATTACCC CAGATCCAGA AGATCATGAT GGAGTTTGAA 
CGGCAGGCAG AGATCATGGA CATGAAGGAA GAAATGATGA ATGACGCAAT TGATGATGCC 
ATGGGTGATG AGGAAGATGA AGAGGAGAGT GATGCTGTTG TGTCCCAGGT CCTGGATGAG 
CTGGGACTGA GCCTCACAGA TGAGCTGTCA AACCTTCCCT CCACTGGAGG CTCACTCAGT 
GTGGCAGCTG GTGGGAAGAA AGCAGAGGCC ACAGCCTCAG CCCTGGCTGA TGCTGATGCA 
GACCTGGAAG AGAGGCTCAA GAACCTTCGC AGGGACTGA

The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.

RefSeq NP_001347662.1
CDS190..708
Translation

Target ORF information:

RefSeq Version NM_001360733.1
Organism Mus musculus(house mouse)
Definition Mus musculus charged multivesicular body protein 2A (Chmp2a), transcript variant 4, mRNA.

Target ORF information:

Epitope DYKDDDDK
Bacterial selection AMPR
Mammalian selection NeoR
Vector pcDNA3.1+/C-(K)DYK
 NM_001360733.1

ORF Insert Sequence:

1
61
121
181
241
301
361
421
481
ATGGACCTGT TGTTTGGGCG CCGGAAGACG CCAGAGGAAC TACTTCGGCA AAACCAGAGG 
GCCCTGAACC GAGCCATGAG AGAACTGGAC AGGGAACGAC AGAAACTAGA AACCCAGGAA 
AAGAAAATCA TTGCGGACAT CAAAAAGATG GCAAAGCAAG GCCAGATGGA TGCTGTTCGA 
ATCATGGCAA AAGACCTGCT GAAATTACCC CAGATCCAGA AGATCATGAT GGAGTTTGAA 
CGGCAGGCAG AGATCATGGA CATGAAGGAA GAAATGATGA ATGACGCAAT TGATGATGCC 
ATGGGTGATG AGGAAGATGA AGAGGAGAGT GATGCTGTTG TGTCCCAGGT CCTGGATGAG 
CTGGGACTGA GCCTCACAGA TGAGCTGTCA AACCTTCCCT CCACTGGAGG CTCACTCAGT 
GTGGCAGCTG GTGGGAAGAA AGCAGAGGCC ACAGCCTCAG CCCTGGCTGA TGCTGATGCA 
GACCTGGAAG AGAGGCTCAA GAACCTTCGC AGGGACTGA

The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.

CloneID OMu84328
Clone ID Related Accession (Same CDS sequence) NM_001360731.1
Accession Version NM_001360731.1 Latest version! Documents for ORF clone product in default vector
Sequence Information ORF Nucleotide Sequence (Length: 522bp)
Protein sequence
SNP
Vector pcDNA3.1+/C-(K)DYK or customized vector User Manual
Clone information Clone Map MSDS
Tag on pcDNA3.1+/C-(K)DYK C terminal DYKDDDDK tags
ORF Insert Method CloneEZ™ Seamless cloning technology
Insert Structure linear
Update Date 2019-02-26
Organism Mus musculus(house mouse)
Product charged multivesicular body protein 2a isoform b
Comment Comment: VALIDATED REFSEQ: This record has undergone validation or preliminary review. The reference sequence was derived from AC121301.8. Transcript Variant: This variant (3) differs in the 5' UTR and uses an alternate splice junction compared to variant 1, that causes a frameshift. The resulting isoform (b) has a shorter and distinct C-terminus compared to isoform a. Sequence Note: The RefSeq transcript and protein were derived from genomic sequence to make the sequence consistent with the reference genome assembly. The genomic coordinates used for the transcript record were based on alignments. ##Evidence-Data-START## RNAseq introns :: single sample supports all introns SAMN00849377, SAMN01164131 [ECO:0000348] ##Evidence-Data-END## COMPLETENESS: complete on the 3' end. 

1
61
121
181
241
301
361
421
481
ATGGACCTGT TGTTTGGGCG CCGGAAGACG CCAGAGGAAC TACTTCGGCA AAACCAGAGG 
GCCCTGAACC GAGCCATGAG AGAACTGGAC AGGGAACGAC AGAAACTAGA AACCCAGGAA 
AAGAAAATCA TTGCGGACAT CAAAAAGATG GCAAAGCAAG GCCAGATGGA TGCTGTTCGA 
ATCATGGCAA AAGACCTGGT GCGTACCCGG AGATATGTAC GCAAGTTTGT GTTGATGCGG 
GCCAACATCC AAGCTGTGTC CCTCAAGATA CAGACTCTAA AATCCAACAA CTCAATGGCA 
CAAGCCATGA AGGGTGTTAC TAAGGCCATG GGCACTATGA ACAGACAGCT GAAATTACCC 
CAGATCCAGA AGATCATGAT GGAGTTTGAA CGGCAGGCAG AGATCATGGA CATGAAGGAA 
GAAATGATGA ATGACGCAAT TGATGATGCC ATGGGTGATG AGGAAGATGA AGAGGAGAGG 
TTGATGCTGT TGTGTCCCAG GTCCTGGATG AGCTGGGACT GA

The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.

RefSeq NP_001347660.1
CDS190..711
Translation

Target ORF information:

RefSeq Version NM_001360731.1
Organism Mus musculus(house mouse)
Definition Mus musculus charged multivesicular body protein 2A (Chmp2a), transcript variant 3, mRNA.

Target ORF information:

Epitope DYKDDDDK
Bacterial selection AMPR
Mammalian selection NeoR
Vector pcDNA3.1+/C-(K)DYK
 NM_001360731.1

ORF Insert Sequence:

1
61
121
181
241
301
361
421
481
ATGGACCTGT TGTTTGGGCG CCGGAAGACG CCAGAGGAAC TACTTCGGCA AAACCAGAGG 
GCCCTGAACC GAGCCATGAG AGAACTGGAC AGGGAACGAC AGAAACTAGA AACCCAGGAA 
AAGAAAATCA TTGCGGACAT CAAAAAGATG GCAAAGCAAG GCCAGATGGA TGCTGTTCGA 
ATCATGGCAA AAGACCTGGT GCGTACCCGG AGATATGTAC GCAAGTTTGT GTTGATGCGG 
GCCAACATCC AAGCTGTGTC CCTCAAGATA CAGACTCTAA AATCCAACAA CTCAATGGCA 
CAAGCCATGA AGGGTGTTAC TAAGGCCATG GGCACTATGA ACAGACAGCT GAAATTACCC 
CAGATCCAGA AGATCATGAT GGAGTTTGAA CGGCAGGCAG AGATCATGGA CATGAAGGAA 
GAAATGATGA ATGACGCAAT TGATGATGCC ATGGGTGATG AGGAAGATGA AGAGGAGAGG 
TTGATGCTGT TGTGTCCCAG GTCCTGGATG AGCTGGGACT GA

The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.

CloneID OMu03216
Clone ID Related Accession (Same CDS sequence) XM_006540345.2 , NM_001360730.1 , XM_006540345.3 , NM_026885.3
Accession Version XM_006540345.2 Documents for ORF clone product in default vector
Sequence Information ORF Nucleotide Sequence (Length: 669bp)
Protein sequence
SNP
Vector pcDNA3.1+/C-(K)DYK or customized vector User Manual
Clone information Clone Map MSDS
Tag on pcDNA3.1+/C-(K)DYK C terminal DYKDDDDK tags
ORF Insert Method CloneEZ™ Seamless cloning technology
Insert Structure linear
Update Date 2015-02-08
Organism Mus musculus(House mouse)
Product charged multivesicular body protein 2a isoform X1
Comment 

1
61
121
181
241
301
361
421
481
541
601
661
ATGGACCTGT TGTTTGGGCG CCGGAAGACG CCAGAGGAAC TACTTCGGCA AAACCAGAGG 
GCCCTGAACC GAGCCATGAG AGAACTGGAC AGGGAACGAC AGAAACTAGA AACCCAGGAA 
AAGAAAATCA TTGCGGACAT CAAAAAGATG GCAAAGCAAG GCCAGATGGA TGCTGTTCGA 
ATCATGGCAA AAGACCTGGT GCGTACCCGG AGATATGTAC GCAAGTTTGT GTTGATGCGG 
GCCAACATCC AAGCTGTGTC CCTCAAGATA CAGACTCTAA AATCCAACAA CTCAATGGCA 
CAAGCCATGA AGGGTGTTAC TAAGGCCATG GGCACTATGA ACAGACAGCT GAAATTACCC 
CAGATCCAGA AGATCATGAT GGAGTTTGAA CGGCAGGCAG AGATCATGGA CATGAAGGAA 
GAAATGATGA ATGACGCAAT TGATGATGCC ATGGGTGATG AGGAAGATGA AGAGGAGAGT 
GATGCTGTTG TGTCCCAGGT CCTGGATGAG CTGGGACTGA GCCTCACAGA TGAGCTGTCA 
AACCTTCCCT CCACTGGAGG CTCACTCAGT GTGGCAGCTG GTGGGAAGAA AGCAGAGGCC 
ACAGCCTCAG CCCTGGCTGA TGCTGATGCA GACCTGGAAG AGAGGCTCAA GAACCTTCGC 
AGGGACTGA

The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.

RefSeq XP_006540408.1
Translation

Target ORF information:

RefSeq Version XM_006540345.2
Organism Mus musculus(House mouse)
Definition Mus musculus charged multivesicular body protein 2A (Chmp2a), transcript variant X3, mRNA.

Target ORF information:

Epitope DYKDDDDK
Bacterial selection AMPR
Mammalian selection NeoR
Vector pcDNA3.1+/C-(K)DYK
 XM_006540345.2

ORF Insert Sequence:

1
61
121
181
241
301
361
421
481
541
601
661
ATGGACCTGT TGTTTGGGCG CCGGAAGACG CCAGAGGAAC TACTTCGGCA AAACCAGAGG 
GCCCTGAACC GAGCCATGAG AGAACTGGAC AGGGAACGAC AGAAACTAGA AACCCAGGAA 
AAGAAAATCA TTGCGGACAT CAAAAAGATG GCAAAGCAAG GCCAGATGGA TGCTGTTCGA 
ATCATGGCAA AAGACCTGGT GCGTACCCGG AGATATGTAC GCAAGTTTGT GTTGATGCGG 
GCCAACATCC AAGCTGTGTC CCTCAAGATA CAGACTCTAA AATCCAACAA CTCAATGGCA 
CAAGCCATGA AGGGTGTTAC TAAGGCCATG GGCACTATGA ACAGACAGCT GAAATTACCC 
CAGATCCAGA AGATCATGAT GGAGTTTGAA CGGCAGGCAG AGATCATGGA CATGAAGGAA 
GAAATGATGA ATGACGCAAT TGATGATGCC ATGGGTGATG AGGAAGATGA AGAGGAGAGT 
GATGCTGTTG TGTCCCAGGT CCTGGATGAG CTGGGACTGA GCCTCACAGA TGAGCTGTCA 
AACCTTCCCT CCACTGGAGG CTCACTCAGT GTGGCAGCTG GTGGGAAGAA AGCAGAGGCC 
ACAGCCTCAG CCCTGGCTGA TGCTGATGCA GACCTGGAAG AGAGGCTCAA GAACCTTCGC 
AGGGACTGA

The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.

CloneID OMu03216
Clone ID Related Accession (Same CDS sequence) XM_006540345.2 , NM_001360730.1 , XM_006540345.3 , NM_026885.3
Accession Version XM_006540345.3 Latest version! Documents for ORF clone product in default vector
Sequence Information ORF Nucleotide Sequence (Length: 669bp)
Protein sequence
SNP
Vector pcDNA3.1+/C-(K)DYK or customized vector User Manual
Clone information Clone Map MSDS
Tag on pcDNA3.1+/C-(K)DYK C terminal DYKDDDDK tags
ORF Insert Method CloneEZ™ Seamless cloning technology
Insert Structure linear
Update Date 2016-06-21
Organism Mus musculus(house mouse)
Product charged multivesicular body protein 2a isoform X2
Comment Comment: MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_000073.6) annotated using gene prediction method: Gnomon, supported by EST evidence. Also see: Documentation of NCBI's Annotation Process On Jun 22, 2016 this sequence version replaced XM_006540345.2. ##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Version :: Mus musculus Annotation Release 106 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 7.1 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END## 

1
61
121
181
241
301
361
421
481
541
601
661
ATGGACCTGT TGTTTGGGCG CCGGAAGACG CCAGAGGAAC TACTTCGGCA AAACCAGAGG 
GCCCTGAACC GAGCCATGAG AGAACTGGAC AGGGAACGAC AGAAACTAGA AACCCAGGAA 
AAGAAAATCA TTGCGGACAT CAAAAAGATG GCAAAGCAAG GCCAGATGGA TGCTGTTCGA 
ATCATGGCAA AAGACCTGGT GCGTACCCGG AGATATGTAC GCAAGTTTGT GTTGATGCGG 
GCCAACATCC AAGCTGTGTC CCTCAAGATA CAGACTCTAA AATCCAACAA CTCAATGGCA 
CAAGCCATGA AGGGTGTTAC TAAGGCCATG GGCACTATGA ACAGACAGCT GAAATTACCC 
CAGATCCAGA AGATCATGAT GGAGTTTGAA CGGCAGGCAG AGATCATGGA CATGAAGGAA 
GAAATGATGA ATGACGCAAT TGATGATGCC ATGGGTGATG AGGAAGATGA AGAGGAGAGT 
GATGCTGTTG TGTCCCAGGT CCTGGATGAG CTGGGACTGA GCCTCACAGA TGAGCTGTCA 
AACCTTCCCT CCACTGGAGG CTCACTCAGT GTGGCAGCTG GTGGGAAGAA AGCAGAGGCC 
ACAGCCTCAG CCCTGGCTGA TGCTGATGCA GACCTGGAAG AGAGGCTCAA GAACCTTCGC 
AGGGACTGA

The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.

RefSeq XP_006540408.1
CDS195..863
Translation

Target ORF information:

RefSeq Version XM_006540345.3
Organism Mus musculus(house mouse)
Definition Mus musculus charged multivesicular body protein 2A (Chmp2a), transcript variant X3, mRNA.

Target ORF information:

Epitope DYKDDDDK
Bacterial selection AMPR
Mammalian selection NeoR
Vector pcDNA3.1+/C-(K)DYK
 XM_006540345.3

ORF Insert Sequence:

1
61
121
181
241
301
361
421
481
541
601
661
ATGGACCTGT TGTTTGGGCG CCGGAAGACG CCAGAGGAAC TACTTCGGCA AAACCAGAGG 
GCCCTGAACC GAGCCATGAG AGAACTGGAC AGGGAACGAC AGAAACTAGA AACCCAGGAA 
AAGAAAATCA TTGCGGACAT CAAAAAGATG GCAAAGCAAG GCCAGATGGA TGCTGTTCGA 
ATCATGGCAA AAGACCTGGT GCGTACCCGG AGATATGTAC GCAAGTTTGT GTTGATGCGG 
GCCAACATCC AAGCTGTGTC CCTCAAGATA CAGACTCTAA AATCCAACAA CTCAATGGCA 
CAAGCCATGA AGGGTGTTAC TAAGGCCATG GGCACTATGA ACAGACAGCT GAAATTACCC 
CAGATCCAGA AGATCATGAT GGAGTTTGAA CGGCAGGCAG AGATCATGGA CATGAAGGAA 
GAAATGATGA ATGACGCAAT TGATGATGCC ATGGGTGATG AGGAAGATGA AGAGGAGAGT 
GATGCTGTTG TGTCCCAGGT CCTGGATGAG CTGGGACTGA GCCTCACAGA TGAGCTGTCA 
AACCTTCCCT CCACTGGAGG CTCACTCAGT GTGGCAGCTG GTGGGAAGAA AGCAGAGGCC 
ACAGCCTCAG CCCTGGCTGA TGCTGATGCA GACCTGGAAG AGAGGCTCAA GAACCTTCGC 
AGGGACTGA

The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.

PubMed

book

Germline Chd8 haploinsufficiency alters brain development in mouse.
Nature neuroscience20(8)1062-1073(2017 Aug)
Gompers AL,Su-Feher L,Ellegood J,Copping NA,Riyadh MA,Stradleigh TW,Pride MC,Schaffler MD,Wade AA,Catta-Preta R,Zdilar I,Louis S,Kaushik G,Mannion BJ,Plajzer-Frick I,Afzal V,Visel A,Pennacchio LA,Dickel DE,Lerch JP,Crawley JN,Zarbalis KS,Silverman JL,Nord AS


book

Mammalian class E Vps proteins, SBP1 and mVps2/CHMP2A, interact with and regulate the function of an AAA-ATPase SKD1/Vps4B.
Journal of cell science117(Pt 14)2997-3009(2004 Jun)
Fujita H,Umezuki Y,Imamura K,Ishikawa D,Uchimura S,Nara A,Yoshimori T,Hayashizaki Y,Kawai J,Ishidoh K,Tanaka Y,Himeno M