This gene encodes a transmembrane and immunoglobulin domain-containing protein. Alternative splicing results in multiple transcript variants, one of which shares its 3' terminal exon with that of the overlapping adenosine A3 receptor gene (GeneID:11542). [provided by RefSeq, Nov 2014].
The following Tmigd3 gene cDNA ORF clone sequences were retrieved from the NCBI Reference Sequence Database (RefSeq). These sequences represent the protein coding region of the Tmigd3 cDNA ORF which is encoded by the open reading frame (ORF) sequence. ORF sequences can be delivered in our standard vector, pcDNA3.1+/C-(K)DYK or the vector of your choice as an expression/transfection-ready ORF clone. Not the clone you want? Click here to find your clone.
transmembrane domain-containing protein TMIGD3 isoform 3
Comment
Comment: VALIDATED REFSEQ: This record has undergone validation or preliminary review. The reference sequence was derived from BC100416.1 and AC121847.2. On Sep 24, 2013 this sequence version replaced NM_001174169.1.
Transcript Variant: This variant (3) includes the same 5' terminal exon but lacks the remaining exons and instead includes an alternate 3' terminal exon, compared to variant 2. The 3' terminal exon is shared with that of the adenosine A3 receptor gene. The encoded isoform (3), which is shorter and distinct compared to isoform 2, represents the C-terminal region of the adenosine A3 receptor.
Sequence Note: This RefSeq record was created from transcript and genomic sequence data to make the sequence consistent with the reference genome assembly. The genomic coordinates used for the transcript record were based on transcript alignments.
##Evidence-Data-START##
RNAseq introns :: single sample supports all introns SAMN00849384 [ECO:0000348]
##Evidence-Data-END##
COMPLETENESS: complete on the 3' end.
transmembrane domain-containing protein TMIGD3 isoform 2 precursor
Comment
Comment: VALIDATED REFSEQ: This record has undergone validation or preliminary review. The reference sequence was derived from AC121847.2, AK005581.1 and BC038878.1. On Sep 24, 2013 this sequence version replaced NM_027025.3.
Transcript Variant: This variant (2) encodes the longer isoform (2), which is a transmembrane and immunoglobulin domain-containing protein and it does not share any similarity with the adenosine A3 receptor.
##Evidence-Data-START##
RNAseq introns :: single sample supports all introns SAMN00849384 [ECO:0000348]
##Evidence-Data-END##
COMPLETENESS: complete on the 3' end.