Gene Symbol | Agk |
Entrez Gene ID | 69923 |
Full Name | acylglycerol kinase |
Synonyms | 2610037M15Rik,6720408I04Rik,AI465370,Mulk |
General protein information |
|
Gene Type | protein-coding |
Organism | Mus musculus(house mouse) |
Genome |
ORF » Species Summary » Mus musculus » Agk cDNA ORF clone
Gene Symbol | Agk |
Entrez Gene ID | 69923 |
Full Name | acylglycerol kinase |
Synonyms | 2610037M15Rik,6720408I04Rik,AI465370,Mulk |
General protein information |
|
Gene Type | protein-coding |
Organism | Mus musculus(house mouse) |
Genome |
mRNA | Protein | Name |
---|---|---|
XM_017321733.1 | XP_017177222.1 | acylglycerol kinase, mitochondrial isoform X3 |
XM_011241458.1 | XP_011239760.1 | acylglycerol kinase, mitochondrial isoform X1 |
XM_006506571.2 | XP_006506634.1 | acylglycerol kinase, mitochondrial isoform X2 |
XM_006506571.3 | XP_006506634.1 | acylglycerol kinase, mitochondrial isoform X2 |
XM_011241458.2 | XP_011239760.1 | acylglycerol kinase, mitochondrial isoform X1 |
NM_023538.2 | NP_076027.1 | acylglycerol kinase, mitochondrial precursor |
AGK | XP_001083626.1 | |
Anopheles gambiae (African malaria mosquito) | AgaP_AGAP005825 | XP_315851.4 |
Xenopus tropicalis (tropical clawed frog) | agk | NP_001090780.1 |
Homo sapiens (human) | AGK | NP_060708.1 |
Canis lupus familiaris (dog) | AGK | XP_005629603.1 |
Danio rerio (zebrafish) | agk | NP_956174.1 |
Drosophila melanogaster (fruit fly) | Mulk | NP_723549.1 |
Bos taurus (cattle) | AGK | NP_001092439.1 |
Rattus norvegicus (Norway rat) | Agk | NP_001120969.1 |
Gallus gallus (chicken) | AGK | XP_416354.2 |
Pan troglodytes (chimpanzee) | AGK | XP_519429.2 |
Mus musculus (house mouse) | Agk | NP_076027.1 |
Acylglycerol kinase promotes cell proliferation and tumorigenicity in breast cancer via suppression of the FOXO1 transcription factor.
Wang X, Lin C, Zhao X, Liu A, Zhu J, Li X, Song L
Molecular cancer13106(2014 May)
Loss of autophagy in erythroid cells leads to defective removal of mitochondria and severe anemia in vivo.
Mortensen M, Ferguson DJ, Edelmann M, Kessler B, Morten KJ, Komatsu M, Simon AK
Proceedings of the National Academy of Sciences of the United States of America107(2)832-7(2010 Jan)
Substrate chirality and specificity of diacylglycerol kinases and the multisubstrate lipid kinase.
Epand RM, Shulga YV, Timmons HC, Perri AL, Belani JD, Perinpanathan K, Johnson-McIntire LB, Bajjalieh S, Dicu AO, Elias C, Rychnovsky SD, Topham MK
Biochemistry46(49)14225-31(2007 Dec)
MuLK, a eukaryotic multi-substrate lipid kinase.
Waggoner DW, Johnson LB, Mann PC, Morris V, Guastella J, Bajjalieh SM
The Journal of biological chemistry279(37)38228-35(2004 Sep)
GeneRIFs: Gene References Into Functions What's a GeneRIF?
AGK promotes cell proliferation and tumorigenicity in breast cancer via suppression of the FOXO1.
Title: Acylglycerol kinase promotes cell proliferation and tumorigenicity in breast cancer via suppression of the FOXO1 transcription factor.
The following Agk gene cDNA ORF clone sequences were retrieved from the NCBI Reference Sequence Database (RefSeq). These sequences represent the protein coding region of the Agk cDNA ORF which is encoded by the open reading frame (ORF) sequence. ORF sequences can be delivered in our standard vector, pcDNA3.1+/C-(K)DYK or the vector of your choice as an expression/transfection-ready ORF clone. Not the clone you want? Click here to find your clone.
CloneID | OMu37562 | |
Clone ID Related Accession (Same CDS sequence) | XM_006506571.2 , XM_006506571.3 | |
Accession Version | XM_006506571.2 | Documents for ORF clone product in default vector |
Sequence Information | ORF Nucleotide Sequence (Length: 990bp) Protein sequence SNP |
|
Vector | pcDNA3.1-C-(k)DYK or customized vector | User Manual |
Clone information | Clone Map | MSDS |
Tag on pcDNA3.1+/C-(K)DYK | C terminal DYKDDDDK tags | |
ORF Insert Method | CloneEZ™ Seamless cloning technology | |
Insert Structure | linear | |
Update Date | 2016-06-21 | |
Organism | Mus musculus(house mouse) | |
Product | acylglycerol kinase, mitochondrial isoform X2 | |
Comment | Comment: MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_000072.6) annotated using gene prediction method: Gnomon, supported by mRNA and EST evidence. Also see: Documentation of NCBI's Annotation Process On Feb 9, 2015 this sequence version replaced XM_006506571.1. ##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Version :: Mus musculus Annotation Release 106 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 7.1 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END## |
1 | ATGGATGTGA CTGTTGTCAA GACGGATTAT GAGGGACAAG CCAAGAAGCT CTTGGAGTTG |
The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.
RefSeq | XP_006506634.1 |
CDS | 3114..4103 |
Translation |
Target ORF information:
Target ORF information:
|
XM_006506571.2 |
1 | ATGGATGTGA CTGTTGTCAA GACGGATTAT GAGGGACAAG CCAAGAAGCT CTTGGAGTTG |
The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.
CloneID | OMu70478 | |
Clone ID Related Accession (Same CDS sequence) | XM_011241458.1 , XM_011241458.2 | |
Accession Version | XM_011241458.1 | Documents for ORF clone product in default vector |
Sequence Information | ORF Nucleotide Sequence (Length: 1230bp) Protein sequence SNP |
|
Vector | pcDNA3.1-C-(k)DYK or customized vector | User Manual |
Clone information | Clone Map | MSDS |
Tag on pcDNA3.1+/C-(K)DYK | C terminal DYKDDDDK tags | |
ORF Insert Method | CloneEZ™ Seamless cloning technology | |
Insert Structure | linear | |
Update Date | 2016-06-21 | |
Organism | Mus musculus(house mouse) | |
Product | acylglycerol kinase, mitochondrial isoform X1 | |
Comment | Comment: MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_000072.6) annotated using gene prediction method: Gnomon, supported by mRNA and EST evidence. Also see: Documentation of NCBI's Annotation Process ##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Version :: Mus musculus Annotation Release 106 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 7.1 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END## |
1 | ATGACTGCAT TCTTTAAAAC GCTTCGAAAT CATTGGAAGA AAACTACAGC TGGGCTCTGT |
The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.
RefSeq | XP_011239760.1 |
CDS | 383..1612 |
Translation |
Target ORF information:
Target ORF information:
|
XM_011241458.1 |
1 | ATGACTGCAT TCTTTAAAAC GCTTCGAAAT CATTGGAAGA AAACTACAGC TGGGCTCTGT |
The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.
CloneID | OMu81796 | |
Clone ID Related Accession (Same CDS sequence) | XM_017321733.1 | |
Accession Version | XM_017321733.1 Latest version! | Documents for ORF clone product in default vector |
Sequence Information | ORF Nucleotide Sequence (Length: 651bp) Protein sequence SNP |
|
Vector | pcDNA3.1-C-(k)DYK or customized vector | User Manual |
Clone information | Clone Map | MSDS |
Tag on pcDNA3.1+/C-(K)DYK | C terminal DYKDDDDK tags | |
ORF Insert Method | CloneEZ™ Seamless cloning technology | |
Insert Structure | linear | |
Update Date | 2016-06-21 | |
Organism | Mus musculus(house mouse) | |
Product | acylglycerol kinase, mitochondrial isoform X3 | |
Comment | Comment: MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_000072.6) annotated using gene prediction method: Gnomon, supported by EST evidence. Also see: Documentation of NCBI's Annotation Process ##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Version :: Mus musculus Annotation Release 106 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 7.1 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END## |
1 | ATGACTGGCC TCCGGTGGGG ATCTTTCAGA GATGCTGGCG TCAAAGTTAG CAAGTACTGG |
The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.
RefSeq | XP_017177222.1 |
CDS | 234..884 |
Translation |
Target ORF information:
Target ORF information:
|
XM_017321733.1 |
1 | ATGACTGGCC TCCGGTGGGG ATCTTTCAGA GATGCTGGCG TCAAAGTTAG CAAGTACTGG |
The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.
CloneID | OMu13573 | |
Clone ID Related Accession (Same CDS sequence) | NM_023538.2 | |
Accession Version | NM_023538.2 Latest version! | Documents for ORF clone product in default vector |
Sequence Information | ORF Nucleotide Sequence (Length: 1266bp) Protein sequence SNP |
|
Vector | pcDNA3.1-C-(k)DYK or customized vector | User Manual |
Clone information | Clone Map | MSDS |
Tag on pcDNA3.1+/C-(K)DYK | C terminal DYKDDDDK tags | |
ORF Insert Method | CloneEZ™ Seamless cloning technology | |
Insert Structure | linear | |
Update Date | 2019-12-27 | |
Organism | Mus musculus(house mouse) | |
Product | acylglycerol kinase, mitochondrial precursor | |
Comment | Comment: VALIDATED REFSEQ: This record has undergone validation or preliminary review. The reference sequence was derived from AC153728.1. On Feb 2, 2010 this sequence version replaced NM_023538.1. Sequence Note: The RefSeq transcript and protein were derived from genomic sequence to make the sequence consistent with the reference genome assembly. The genomic coordinates used for the transcript record were based on alignments. ##Evidence-Data-START## Transcript exon combination :: BC019145.1, SRR1660813.207108.1 [ECO:0000332] RNAseq introns :: single sample supports all introns SAMN00849374, SAMN00849375 [ECO:0000348] ##Evidence-Data-END## ##RefSeq-Attributes-START## gene product(s) localized to mito. :: reported by MitoCarta ##RefSeq-Attributes-END## COMPLETENESS: complete on the 3' end. |
1 | ATGACTGCAT TCTTTAAAAC GCTTCGAAAT CATTGGAAGA AAACTACAGC TGGGCTCTGT |
The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.
RefSeq | NP_076027.1 |
CDS | 60..1325 |
Translation |
Target ORF information:
Target ORF information:
|
NM_023538.2 |
1 | ATGACTGCAT TCTTTAAAAC GCTTCGAAAT CATTGGAAGA AAACTACAGC TGGGCTCTGT |
The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.
CloneID | OMu37562 | |
Clone ID Related Accession (Same CDS sequence) | XM_006506571.2 , XM_006506571.3 | |
Accession Version | XM_006506571.3 Latest version! | Documents for ORF clone product in default vector |
Sequence Information | ORF Nucleotide Sequence (Length: 990bp) Protein sequence SNP |
|
Vector | pcDNA3.1-C-(k)DYK or customized vector | User Manual |
Clone information | Clone Map | MSDS |
Tag on pcDNA3.1+/C-(K)DYK | C terminal DYKDDDDK tags | |
ORF Insert Method | CloneEZ™ Seamless cloning technology | |
Insert Structure | linear | |
Update Date | 2019-08-07 | |
Organism | Mus musculus(house mouse) | |
Product | acylglycerol kinase, mitochondrial isoform X2 | |
Comment | Comment: MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_000072.6) annotated using gene prediction method: Gnomon, supported by mRNA and EST evidence. Also see: Documentation of NCBI's Annotation Process On Aug 8, 2019 this sequence version replaced XM_006506571.2. ##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Name :: Mus musculus Annotation Release 108 Annotation Version :: 108 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 8.2 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END## |
1 | ATGGATGTGA CTGTTGTCAA GACGGATTAT GAGGGACAAG CCAAGAAGCT CTTGGAGTTG |
The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.
RefSeq | XP_006506634.1 |
CDS | 3114..4103 |
Translation |
Target ORF information:
Target ORF information:
|
XM_006506571.3 |
1 | ATGGATGTGA CTGTTGTCAA GACGGATTAT GAGGGACAAG CCAAGAAGCT CTTGGAGTTG |
The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.
CloneID | OMu70478 | |
Clone ID Related Accession (Same CDS sequence) | XM_011241458.1 , XM_011241458.2 | |
Accession Version | XM_011241458.2 Latest version! | Documents for ORF clone product in default vector |
Sequence Information | ORF Nucleotide Sequence (Length: 1230bp) Protein sequence SNP |
|
Vector | pcDNA3.1-C-(k)DYK or customized vector | User Manual |
Clone information | Clone Map | MSDS |
Tag on pcDNA3.1+/C-(K)DYK | C terminal DYKDDDDK tags | |
ORF Insert Method | CloneEZ™ Seamless cloning technology | |
Insert Structure | linear | |
Update Date | 2019-08-07 | |
Organism | Mus musculus(house mouse) | |
Product | acylglycerol kinase, mitochondrial isoform X1 | |
Comment | Comment: MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_000072.6) annotated using gene prediction method: Gnomon, supported by mRNA and EST evidence. Also see: Documentation of NCBI's Annotation Process On Aug 8, 2019 this sequence version replaced XM_011241458.1. ##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Name :: Mus musculus Annotation Release 108 Annotation Version :: 108 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 8.2 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END## |
1 | ATGACTGCAT TCTTTAAAAC GCTTCGAAAT CATTGGAAGA AAACTACAGC TGGGCTCTGT |
The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.
RefSeq | XP_011239760.1 |
CDS | 462..1691 |
Translation |
Target ORF information:
Target ORF information:
|
XM_011241458.2 |
1 | ATGACTGCAT TCTTTAAAAC GCTTCGAAAT CATTGGAAGA AAACTACAGC TGGGCTCTGT |
The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.
Acylglycerol kinase promotes cell proliferation and tumorigenicity in breast cancer via suppression of the FOXO1 transcription factor. |
Loss of autophagy in erythroid cells leads to defective removal of mitochondria and severe anemia in vivo. |
Substrate chirality and specificity of diacylglycerol kinases and the multisubstrate lipid kinase. |
MuLK, a eukaryotic multi-substrate lipid kinase. |