Gene Symbol | Znhit1 |
Entrez Gene ID | 70103 |
Full Name | zinc finger, HIT domain containing 1 |
Synonyms | 2700001K05Rik,ZNFN4A1 |
General protein information |
|
Gene Type | protein-coding |
Organism | Mus musculus(house mouse) |
Genome |
ORF » Species Summary » Mus musculus » Znhit1 cDNA ORF clone
gRNAs
Gene Symbol | Znhit1 |
Entrez Gene ID | 70103 |
Full Name | zinc finger, HIT domain containing 1 |
Synonyms | 2700001K05Rik,ZNFN4A1 |
General protein information |
|
Gene Type | protein-coding |
Organism | Mus musculus(house mouse) |
Genome |
mRNA | Protein | Name |
---|---|---|
XM_006504497.4 | XP_006504560.1 | zinc finger HIT domain-containing protein 1 isoform X1 |
NM_001310747.1 | NP_001297676.1 | zinc finger HIT domain-containing protein 1 isoform 2 |
NM_027318.4 | NP_081594.1 | zinc finger HIT domain-containing protein 1 isoform 1 |
XM_006504497.3 | XP_006504560.1 | zinc finger HIT domain-containing protein 1 isoform X1 |
NM_001310748.1 | NP_001297677.1 | zinc finger HIT domain-containing protein 1 isoform 3 |
ZNHIT1 | XP_001107951.1 | |
Rattus norvegicus (Norway rat) | Znhit1 | NP_001258279.1 |
Danio rerio (zebrafish) | znhit1 | NP_001017401.1 |
Caenorhabditis elegans (roundworm) | zhit-1 | NP_001122894.1 |
Xenopus tropicalis (tropical clawed frog) | znhit1 | NP_001017056.2 |
Canis lupus familiaris (dog) | ZNHIT1 | XP_536855.2 |
Drosophila melanogaster (fruit fly) | CG31917 | NP_608895.1 |
Pan troglodytes (chimpanzee) | ZNHIT1 | XP_527843.2 |
Mus musculus (house mouse) | Znhit1 | NP_081594.1 |
Anopheles gambiae (African malaria mosquito) | AgaP_AGAP007853 | XP_317641.2 |
Homo sapiens (human) | ZNHIT1 | NP_006340.1 |
Bos taurus (cattle) | ZNHIT1 | NP_001039650.1 |
Essential role of p18Hamlet/SRCAP-mediated histone H2A.Z chromatin incorporation in muscle differentiation.
Cuadrado A, Corrado N, Perdiguero E, Lafarga V, Mu?oz-Canoves P, Nebreda AR
The EMBO journal29(12)2014-25(2010 Jun)
Znhit1 causes cell cycle arrest and down-regulates CDK6 expression.
Yang Z, Cao Y, Zhu X, Huang Y, Ding Y, Liu X
Biochemical and biophysical research communications386(1)146-52(2009 Aug)
GeneRIFs: Gene References Into Functions What's a GeneRIF?
These results identify SRCAP/H2A.Z-mediated chromatin remodelling as a key early event in muscle differentiation-specific gene expression.
Title: Essential role of p18Hamlet/SRCAP-mediated histone H2A.Z chromatin incorporation in muscle differentiation.
These findings identified Znhit1 as a CDK6 regulator that plays an important role in cell proliferation.
Title: Znhit1 causes cell cycle arrest and down-regulates CDK6 expression.
The following Znhit1 gene cDNA ORF clone sequences were retrieved from the NCBI Reference Sequence Database (RefSeq). These sequences represent the protein coding region of the Znhit1 cDNA ORF which is encoded by the open reading frame (ORF) sequence. ORF sequences can be delivered in our standard vector, pcDNA3.1+/C-(K)DYK or the vector of your choice as an expression/transfection-ready ORF clone. Not the clone you want? Click here to find your clone.
CloneID | OMu70498 | |
Clone ID Related Accession (Same CDS sequence) | NM_001310747.1 | |
Accession Version | NM_001310747.1 Latest version! | Documents for ORF clone product in default vector |
Sequence Information | ORF Nucleotide Sequence (Length: 465bp) Protein sequence SNP |
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Vector | pcDNA3.1-C-(k)DYK or customized vector | ![]() |
Clone information | Clone Map | ![]() |
Tag on pcDNA3.1+/C-(K)DYK | C terminal DYKDDDDK tags | |
ORF Insert Method | CloneEZ™ Seamless cloning technology | |
Insert Structure | linear | |
Update Date | 2019-10-21 | |
Organism | Mus musculus(house mouse) | |
Product | zinc finger HIT domain-containing protein 1 isoform 2 | |
Comment | Comment: VALIDATED REFSEQ: This record has undergone validation or preliminary review. The reference sequence was derived from AI426440.1, BY084904.1, AA002885.1 and AI841783.1. On Jul 18, 2015 this sequence version replaced XM_006504498.2. Transcript Variant: This variant (2) differs in the 5' UTR and 5' coding region compared to variant 1. The encoded isoform (2) has a longer, distinct N-terminus than isoform 1. ##Evidence-Data-START## Transcript exon combination :: BU946467.1, CA464501.1 [ECO:0000332] RNAseq introns :: single sample supports all introns SAMN00849384 [ECO:0000348] ##Evidence-Data-END## COMPLETENESS: complete on the 3' end. |
1 | ATGGTGGAGA AGAAACCCGC CGTTCGCTCC CAGGACCCTG GACAGCGGCG GGTGCTGGAC |
The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.
RefSeq | NP_001297676.1 |
CDS | 73..537 |
Translation |
Target ORF information:
Target ORF information:
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1 | ATGGTGGAGA AGAAACCCGC CGTTCGCTCC CAGGACCCTG GACAGCGGCG GGTGCTGGAC |
The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.
CloneID | OMu04042 | |
Clone ID Related Accession (Same CDS sequence) | NM_027318.4 | |
Accession Version | NM_027318.4 Latest version! | Documents for ORF clone product in default vector |
Sequence Information | ORF Nucleotide Sequence (Length: 462bp) Protein sequence SNP |
|
Vector | pcDNA3.1-C-(k)DYK or customized vector | ![]() |
Clone information | Clone Map | ![]() |
Tag on pcDNA3.1+/C-(K)DYK | C terminal DYKDDDDK tags | |
ORF Insert Method | CloneEZ™ Seamless cloning technology | |
Insert Structure | linear | |
Update Date | 2019-04-15 | |
Organism | Mus musculus(house mouse) | |
Product | zinc finger HIT domain-containing protein 1 isoform 1 | |
Comment | Comment: VALIDATED REFSEQ: This record has undergone validation or preliminary review. The reference sequence was derived from CX202132.1, AK080799.1 and AI841783.1. On Jul 18, 2015 this sequence version replaced NM_027318.3. Transcript Variant: This variant (1) represents the longest transcript and encodes the shortest isoform (1). ##Evidence-Data-START## Transcript exon combination :: CB196200.1, AK080799.1 [ECO:0000332] RNAseq introns :: single sample supports all introns SAMN01164132, SAMN01164137 [ECO:0000348] ##Evidence-Data-END## COMPLETENESS: complete on the 3' end. |
1 | ATGCAGACGG CGAGACAAGT TCGCTCCCAG GACCCTGGAC AGCGGCGGGT GCTGGACAGG |
The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.
RefSeq | NP_081594.1 |
CDS | 453..914 |
Translation |
Target ORF information:
Target ORF information:
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1 | ATGCAGACGG CGAGACAAGT TCGCTCCCAG GACCCTGGAC AGCGGCGGGT GCTGGACAGG |
The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.
CloneID | OMu36192 | |
Clone ID Related Accession (Same CDS sequence) | XM_006504497.4 , XM_006504497.3 , NM_001310748.1 | |
Accession Version | NM_001310748.1 Latest version! | Documents for ORF clone product in default vector |
Sequence Information | ORF Nucleotide Sequence (Length: 477bp) Protein sequence SNP |
|
Vector | pcDNA3.1-C-(k)DYK or customized vector | ![]() |
Clone information | Clone Map | ![]() |
Tag on pcDNA3.1+/C-(K)DYK | C terminal DYKDDDDK tags | |
ORF Insert Method | CloneEZ™ Seamless cloning technology | |
Insert Structure | linear | |
Update Date | 2019-04-14 | |
Organism | Mus musculus(house mouse) | |
Product | zinc finger HIT domain-containing protein 1 isoform 3 | |
Comment | Comment: VALIDATED REFSEQ: This record has undergone validation or preliminary review. The reference sequence was derived from AC147987.5. On Jul 18, 2015 this sequence version replaced XM_006504496.1. Transcript Variant: This variant (3) differs in the 5' UTR and 5' coding region compared to variant 1. The encoded isoform (3) has a longer, distinct N-terminus than isoform 1. Sequence Note: The RefSeq transcript and protein were derived from genomic sequence to make the sequence consistent with the reference genome assembly. The genomic coordinates used for the transcript record were based on alignments. ##Evidence-Data-START## CDS exon combination :: BI456103.1 [ECO:0000331] RNAseq introns :: single sample supports all introns SAMN00849382, SAMN00849384 [ECO:0000348] ##Evidence-Data-END## COMPLETENESS: complete on the 3' end. |
1 | ATGTTATGGG AAACCCAGCA CCAGGAATGG GCAGTTCGCT CCCAGGACCC TGGACAGCGG |
The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.
RefSeq | NP_001297677.1 |
CDS | 191..667 |
Translation |
Target ORF information:
Target ORF information:
|
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1 | ATGTTATGGG AAACCCAGCA CCAGGAATGG GCAGTTCGCT CCCAGGACCC TGGACAGCGG |
The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.
CloneID | OMu36192 | |
Clone ID Related Accession (Same CDS sequence) | XM_006504497.4 , XM_006504497.3 , NM_001310748.1 | |
Accession Version | XM_006504497.3 | Documents for ORF clone product in default vector |
Sequence Information | ORF Nucleotide Sequence (Length: 477bp) Protein sequence SNP |
|
Vector | pcDNA3.1-C-(k)DYK or customized vector | ![]() |
Clone information | Clone Map | ![]() |
Tag on pcDNA3.1+/C-(K)DYK | C terminal DYKDDDDK tags | |
ORF Insert Method | CloneEZ™ Seamless cloning technology | |
Insert Structure | linear | |
Update Date | 2016-06-21 | |
Organism | Mus musculus(house mouse) | |
Product | zinc finger HIT domain-containing protein 1 isoform X1 | |
Comment | Comment: MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_000071.6) annotated using gene prediction method: Gnomon, supported by EST evidence. Also see: Documentation of NCBI's Annotation Process On Jun 22, 2016 this sequence version replaced XM_006504497.2. ##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Version :: Mus musculus Annotation Release 106 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 7.1 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END## |
1 | ATGTTATGGG AAACCCAGCA CCAGGAATGG GCAGTTCGCT CCCAGGACCC TGGACAGCGG |
The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.
RefSeq | XP_006504560.1 |
CDS | 117..593 |
Translation |
Target ORF information:
Target ORF information:
|
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1 | ATGTTATGGG AAACCCAGCA CCAGGAATGG GCAGTTCGCT CCCAGGACCC TGGACAGCGG |
The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.
CloneID | OMu36192 | |
Clone ID Related Accession (Same CDS sequence) | XM_006504497.4 , XM_006504497.3 , NM_001310748.1 | |
Accession Version | XM_006504497.4 Latest version! | Documents for ORF clone product in default vector |
Sequence Information | ORF Nucleotide Sequence (Length: 477bp) Protein sequence SNP |
|
Vector | pcDNA3.1-C-(k)DYK or customized vector | ![]() |
Clone information | Clone Map | ![]() |
Tag on pcDNA3.1+/C-(K)DYK | C terminal DYKDDDDK tags | |
ORF Insert Method | CloneEZ™ Seamless cloning technology | |
Insert Structure | linear | |
Update Date | 2019-08-07 | |
Organism | Mus musculus(house mouse) | |
Product | zinc finger HIT domain-containing protein 1 isoform X1 | |
Comment | Comment: MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_000071.6) annotated using gene prediction method: Gnomon, supported by EST evidence. Also see: Documentation of NCBI's Annotation Process On Aug 8, 2019 this sequence version replaced XM_006504497.3. ##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Name :: Mus musculus Annotation Release 108 Annotation Version :: 108 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 8.2 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END## |
1 | ATGTTATGGG AAACCCAGCA CCAGGAATGG GCAGTTCGCT CCCAGGACCC TGGACAGCGG |
The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.
RefSeq | XP_006504560.1 |
CDS | 141..617 |
Translation |
Target ORF information:
Target ORF information:
|
![]() |
1 | ATGTTATGGG AAACCCAGCA CCAGGAATGG GCAGTTCGCT CCCAGGACCC TGGACAGCGG |
The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.
Essential role of p18Hamlet/SRCAP-mediated histone H2A.Z chromatin incorporation in muscle differentiation. |
Znhit1 causes cell cycle arrest and down-regulates CDK6 expression. |