| Gene Symbol | Pak4 |
| Entrez Gene ID | 70584 |
| Full Name | p21 protein (Cdc42/Rac)-activated kinase 4 |
| Synonyms | 5730488L07Rik,AW555722,mKIAA1142 |
| General protein information |
|
| Gene Type | protein-coding |
| Organism | Mus musculus(house mouse) |
| Genome |
The following Pak4 gene cDNA ORF clone sequences were retrieved from the NCBI Reference Sequence Database (RefSeq). These sequences represent the protein coding region of the Pak4 cDNA ORF which is encoded by the open reading frame (ORF) sequence. ORF sequences can be delivered in our standard vector, pcDNA3.1+/C-(K)DYK or the vector of your choice as an expression/transfection-ready ORF clone. Not the clone you want? Click here to find your clone.
| CloneID | OMu14793 | |
| Clone ID Related Accession (Same CDS sequence) | XM_017312296.1 , NM_027470.3 , XM_017312297.1 | |
| Accession Version | NM_027470.3 Latest version! | Documents for ORF clone product in default vector |
| Sequence Information | ORF Nucleotide Sequence (Length: 1782bp) Protein sequence SNP |
|
| Vector | pcDNA3.1-C-(k)DYK or customized vector |  User Manual |
| Clone information | Clone Map | MSDS |
| Tag on pcDNA3.1+/C-(K)DYK | C terminal DYKDDDDK tags | |
| ORF Insert Method | CloneEZ™ Seamless cloning technology | |
| Insert Structure | linear | |
| Update Date | 2019-12-25 | |
| Organism | Mus musculus(house mouse) | |
| Product | serine/threonine-protein kinase PAK 4 | |
| Comment | Comment: VALIDATED REFSEQ: This record has undergone validation or preliminary review. The reference sequence was derived from BY197606.1, BB839524.1, CF172418.1, BQ572351.1, AC136456.3 and AK017713.1. On Dec 20, 2006 this sequence version replaced NM_027470.2. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Gene record to access additional publications. ##Evidence-Data-START## Transcript exon combination :: AK129298.2, AK088512.1 [ECO:0000332] RNAseq introns :: single sample supports all introns SAMN00849382, SAMN00849384 [ECO:0000348] ##Evidence-Data-END## | |
1 | ATGTTTGGAA AGAAGAAGAA GCGGGTGGAG ATCTCAGCCC CATCCAACTT CGAGCACCGT |
The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.
| RefSeq | NP_081746.1 |
| CDS | 286..2067 |
| Translation |
Target ORF information:
Target ORF information:
|
 NM_027470.3 |
1 | ATGTTTGGAA AGAAGAAGAA GCGGGTGGAG ATCTCAGCCC CATCCAACTT CGAGCACCGT |
The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.
| CloneID | OMu14793 | |
| Clone ID Related Accession (Same CDS sequence) | XM_017312296.1 , NM_027470.3 , XM_017312297.1 | |
| Accession Version | XM_017312296.1 Latest version! | Documents for ORF clone product in default vector |
| Sequence Information | ORF Nucleotide Sequence (Length: 1782bp) Protein sequence SNP |
|
| Vector | pcDNA3.1-C-(k)DYK or customized vector | User Manual |
| Clone information | Clone Map | MSDS |
| Tag on pcDNA3.1+/C-(K)DYK | C terminal DYKDDDDK tags | |
| ORF Insert Method | CloneEZ™ Seamless cloning technology | |
| Insert Structure | linear | |
| Update Date | 2019-08-07 | |
| Organism | Mus musculus(house mouse) | |
| Product | serine/threonine-protein kinase PAK 4 isoform X1 | |
| Comment | Comment: MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_000073.6) annotated using gene prediction method: Gnomon, supported by mRNA and EST evidence. Also see: Documentation of NCBI's Annotation Process ##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Name :: Mus musculus Annotation Release 108 Annotation Version :: 108 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 8.2 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END## | |
1 | ATGTTTGGAA AGAAGAAGAA GCGGGTGGAG ATCTCAGCCC CATCCAACTT CGAGCACCGT |
The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.
| RefSeq | XP_017167785.1 |
| CDS | 428..2209 |
| Translation |
Target ORF information:
Target ORF information:
|
XM_017312296.1 |
1 | ATGTTTGGAA AGAAGAAGAA GCGGGTGGAG ATCTCAGCCC CATCCAACTT CGAGCACCGT |
The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.
| CloneID | OMu14793 | |
| Clone ID Related Accession (Same CDS sequence) | XM_017312296.1 , NM_027470.3 , XM_017312297.1 | |
| Accession Version | XM_017312297.1 Latest version! | Documents for ORF clone product in default vector |
| Sequence Information | ORF Nucleotide Sequence (Length: 1782bp) Protein sequence SNP |
|
| Vector | pcDNA3.1-C-(k)DYK or customized vector | User Manual |
| Clone information | Clone Map | MSDS |
| Tag on pcDNA3.1+/C-(K)DYK | C terminal DYKDDDDK tags | |
| ORF Insert Method | CloneEZ™ Seamless cloning technology | |
| Insert Structure | linear | |
| Update Date | 2019-08-07 | |
| Organism | Mus musculus(house mouse) | |
| Product | serine/threonine-protein kinase PAK 4 isoform X1 | |
| Comment | Comment: MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_000073.6) annotated using gene prediction method: Gnomon, supported by mRNA and EST evidence. Also see: Documentation of NCBI's Annotation Process ##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Name :: Mus musculus Annotation Release 108 Annotation Version :: 108 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 8.2 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END## | |
1 | ATGTTTGGAA AGAAGAAGAA GCGGGTGGAG ATCTCAGCCC CATCCAACTT CGAGCACCGT |
The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.
| RefSeq | XP_017167786.1 |
| CDS | 282..2063 |
| Translation |
Target ORF information:
Target ORF information:
|
XM_017312297.1 |
1 | ATGTTTGGAA AGAAGAAGAA GCGGGTGGAG ATCTCAGCCC CATCCAACTT CGAGCACCGT |
The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.
PAK4 crystal structures suggest unusual kinase conformational movements. |
Pdx1-Cre-driven conditional gene depletion suggests PAK4 as dispensable for mouse pancreas development. |
Increased Circulating Endothelial Microparticles Associated with PAK4 Play a Key Role in Ventilation-Induced Lung Injury Process. |
High-throughput screening of mouse gene knockouts identifies established and novel skeletal phenotypes. |
