Gene Symbol | Tspan2 |
Entrez Gene ID | 70747 |
Full Name | tetraspanin 2 |
Synonyms | 6330415F13Rik,B230119D02Rik,tspan-2 |
General protein information |
|
Gene Type | protein-coding |
Organism | Mus musculus(house mouse) |
Genome |
ORF » Species Summary » Mus musculus » Tspan2 cDNA ORF clone
gRNAs
Gene Symbol | Tspan2 |
Entrez Gene ID | 70747 |
Full Name | tetraspanin 2 |
Synonyms | 6330415F13Rik,B230119D02Rik,tspan-2 |
General protein information |
|
Gene Type | protein-coding |
Organism | Mus musculus(house mouse) |
Genome |
mRNA | Protein | Name |
---|---|---|
NM_001243132.1 | NP_001230061.1 | tetraspanin-2 isoform 2 |
NM_027533.3 | NP_081809.2 | tetraspanin-2 isoform 1 |
Mus musculus (house mouse) | Tspan2 | NP_081809.2 |
Xenopus tropicalis (tropical clawed frog) | tspan2 | NP_001106532.1 |
Homo sapiens (human) | TSPAN2 | NP_005716.2 |
Pan troglodytes (chimpanzee) | TSPAN2 | XP_513675.4 |
Rattus norvegicus (Norway rat) | Tspan2 | NP_072111.1 |
Gallus gallus (chicken) | TSPAN2 | XP_004935062.1 |
LOC709463 | XP_001111915.1 | |
Canis lupus familiaris (dog) | TSPAN2 | XP_848759.1 |
Bos taurus (cattle) | TSPAN2 | NP_001029829.1 |
Uncoupling of neuroinflammation from axonal degeneration in mice lacking the myelin protein tetraspanin-2.
de Monasterio-Schrader P, Patzig J, M?bius W, Barrette B, Wagner TL, Kusch K, Edgar JM, Brophy PJ, Werner HB
Glia61(11)1832-47(2013 Nov)
Planar cell polarity defects and defective Vangl2 trafficking in mutants for the COPII gene Sec24b.
Wansleeben C, Feitsma H, Montcouquiol M, Kroon C, Cuppen E, Meijlink F
Development (Cambridge, England)137(7)1067-73(2010 Apr)
Convergent functional genomics of oligodendrocyte differentiation identifies multiple autoinhibitory signaling circuits.
Gobert RP, Joubert L, Curchod ML, Salvat C, Foucault I, Jorand-Lebrun C, Lamarine M, Peixoto H, Vignaud C, Fr?maux C, Jomotte T, Fran?on B, Alliod C, Bernasconi L, Abderrahim H, Perrin D, Bombrun A, Zanoguera F, Rommel C, Hooft van Huijsduijnen R
Molecular and cellular biology29(6)1538-53(2009 Mar)
Appearance of new tetraspanin genes during vertebrate evolution.
Garcia-Espa?a A, Chung PJ, Sarkar IN, Stiner E, Sun TT, Desalle R
Genomics91(4)326-34(2008 Apr)
GeneRIFs: Gene References Into Functions What's a GeneRIF?
the activation of astrocytes and microglia was strongly enhanced in Tspan2(null) *Plp1(null) double-mutants compared with either single-mutant
Title: Uncoupling of neuroinflammation from axonal degeneration in mice lacking the myelin protein tetraspanin-2.
The following Tspan2 gene cDNA ORF clone sequences were retrieved from the NCBI Reference Sequence Database (RefSeq). These sequences represent the protein coding region of the Tspan2 cDNA ORF which is encoded by the open reading frame (ORF) sequence. ORF sequences can be delivered in our standard vector, pcDNA3.1+/C-(K)DYK or the vector of your choice as an expression/transfection-ready ORF clone. Not the clone you want? Click here to find your clone.
CloneID | OMu23206 | |
Clone ID Related Accession (Same CDS sequence) | NM_027533.3 | |
Accession Version | NM_027533.3 Latest version! | Documents for ORF clone product in default vector |
Sequence Information | ORF Nucleotide Sequence (Length: 666bp) Protein sequence SNP |
|
Vector | pcDNA3.1-C-(k)DYK or customized vector | ![]() |
Clone information | Clone Map | ![]() |
Tag on pcDNA3.1+/C-(K)DYK | C terminal DYKDDDDK tags | |
ORF Insert Method | CloneEZ™ Seamless cloning technology | |
Insert Structure | linear | |
Update Date | 2019-10-21 | |
Organism | Mus musculus(house mouse) | |
Product | tetraspanin-2 isoform 1 | |
Comment | Comment: VALIDATED REFSEQ: This record has undergone validation or preliminary review. The reference sequence was derived from AC134871.3, AK079560.1 and AK018178.1. On Jul 27, 2011 this sequence version replaced NM_027533.2. Transcript Variant: This variant (1) represents the longer transcript and encodes the longer isoform (1). Sequence Note: This RefSeq record was created from transcript and genomic sequence data to make the sequence consistent with the reference genome assembly. The genomic coordinates used for the transcript record were based on transcript alignments. ##Evidence-Data-START## Transcript exon combination :: AK079560.1, AK049888.1 [ECO:0000332] RNAseq introns :: single sample supports all introns SAMN00849374, SAMN00849375 [ECO:0000348] ##Evidence-Data-END## COMPLETENESS: complete on the 3' end. |
1 | ATGGGGCGTT TTCGCGGGGG CCTGCGGTGC ATCAAGTATC TGCTGCTCGG CTTCAACCTG |
The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.
RefSeq | NP_081809.2 |
CDS | 228..893 |
Translation |
Target ORF information:
Target ORF information:
|
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1 | ATGGGGCGTT TTCGCGGGGG CCTGCGGTGC ATCAAGTATC TGCTGCTCGG CTTCAACCTG |
The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.
CloneID | OMu23244 | |
Clone ID Related Accession (Same CDS sequence) | NM_001243132.1 | |
Accession Version | NM_001243132.1 Latest version! | Documents for ORF clone product in default vector |
Sequence Information | ORF Nucleotide Sequence (Length: 654bp) Protein sequence SNP |
|
Vector | pcDNA3.1-C-(k)DYK or customized vector | ![]() |
Clone information | Clone Map | ![]() |
Tag on pcDNA3.1+/C-(K)DYK | C terminal DYKDDDDK tags | |
ORF Insert Method | CloneEZ™ Seamless cloning technology | |
Insert Structure | linear | |
Update Date | 2019-02-22 | |
Organism | Mus musculus(house mouse) | |
Product | tetraspanin-2 isoform 2 | |
Comment | Comment: VALIDATED REFSEQ: This record has undergone validation or preliminary review. The reference sequence was derived from AK020982.1, AK160479.1 and AC134871.3. Transcript Variant: This variant (2) differs in the 5' UTR and uses an alternate start codon, compared to variant 1. The encoded isoform (2) has a shorter and distinct N-terminus, compared to isoform 1. Sequence Note: This RefSeq record was created from transcript and genomic sequence data to make the sequence consistent with the reference genome assembly. The genomic coordinates used for the transcript record were based on transcript alignments. ##Evidence-Data-START## Transcript exon combination :: AK020982.1, SRR1660813.132386.1 [ECO:0000332] RNAseq introns :: single sample supports all introns SAMN00849376, SAMN00849382 [ECO:0000348] ##Evidence-Data-END## COMPLETENESS: complete on the 3' end. |
1 | ATGCTCCCCC GAAAGAAGCC ATCATCTTCG GCGGCATCGC CCGGCGGGTG GCGCCAGCTA |
The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.
RefSeq | NP_001230061.1 |
CDS | 45..698 |
Translation |
Target ORF information:
Target ORF information:
|
![]() |
1 | ATGCTCCCCC GAAAGAAGCC ATCATCTTCG GCGGCATCGC CCGGCGGGTG GCGCCAGCTA |
The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.
Uncoupling of neuroinflammation from axonal degeneration in mice lacking the myelin protein tetraspanin-2. |
Planar cell polarity defects and defective Vangl2 trafficking in mutants for the COPII gene Sec24b. |
Convergent functional genomics of oligodendrocyte differentiation identifies multiple autoinhibitory signaling circuits. |
Appearance of new tetraspanin genes during vertebrate evolution. |