Gene Symbol | Arhgap42 |
Entrez Gene ID | 71544 |
Full Name | Rho GTPase activating protein 42 |
Synonyms | 9030420J04Rik,BE136619 |
General protein information |
|
Gene Type | protein-coding |
Organism | Mus musculus(house mouse) |
Genome |
ORF » Species Summary » Mus musculus » Arhgap42 cDNA ORF clone
Gene Symbol | Arhgap42 |
Entrez Gene ID | 71544 |
Full Name | Rho GTPase activating protein 42 |
Synonyms | 9030420J04Rik,BE136619 |
General protein information |
|
Gene Type | protein-coding |
Organism | Mus musculus(house mouse) |
Genome |
mRNA | Protein | Name |
---|---|---|
XM_006509884.3 | XP_006509947.1 | rho GTPase-activating protein 42 isoform X1 |
NM_027823.1 | NP_082099.1 | rho GTPase-activating protein 42 |
NM_001372568.1 | NP_001359497.1 | rho GTPase-activating protein 42 isoform 7 |
NM_001372569.1 | NP_001359498.1 | rho GTPase-activating protein 42 isoform 8 |
NM_001372565.1 | NP_001359494.1 | rho GTPase-activating protein 42 isoform 4 |
NM_001372567.1 | NP_001359496.1 | rho GTPase-activating protein 42 isoform 6 |
NM_001372570.1 | NP_001359499.1 | rho GTPase-activating protein 42 isoform 9 |
NM_001372564.1 | NP_001359493.1 | rho GTPase-activating protein 42 isoform 2 |
NM_027823.2 | NP_082099.1 | rho GTPase-activating protein 42 isoform 3 |
NM_001372563.1 | NP_001359492.1 | rho GTPase-activating protein 42 isoform 1 |
NM_001372566.1 | NP_001359495.1 | rho GTPase-activating protein 42 isoform 5 |
Rattus norvegicus (Norway rat) | Arhgap42 | XP_576354.3 |
Homo sapiens (human) | ARHGAP42 | NP_689645.2 |
Canis lupus familiaris (dog) | ARHGAP42 | XP_533968.4 |
Danio rerio (zebrafish) | arhgap42 | XP_698022.5 |
ARHGAP42 | XP_002799830.1 | |
Mus musculus (house mouse) | Arhgap42 | NP_082099.1 |
Xenopus tropicalis (tropical clawed frog) | arhgap42 | XP_002935619.1 |
Pan troglodytes (chimpanzee) | ARHGAP42 | XP_001148638.2 |
Bos taurus (cattle) | ARHGAP42 | XP_003586980.1 |
Gallus gallus (chicken) | ARHGAP42 | XP_417185.3 |
ARHGAP42 is activated by Src-mediated tyrosine phosphorylation to promote cell motility.
Luo W, Jano?tiak R, Tolde O, Ryzhova LM, Koudelkov? L, Dibus M, Br?bek J, Hanks SK, Rosel D
Journal of cell science130(14)2382-2393(2017 Jul)
Blood pressure-associated polymorphism controls ARHGAP42 expression via serum response factor DNA binding.
Bai X, Mangum KD, Dee RA, Stouffer GA, Lee CR, Oni-Orisan A, Patterson C, Schisler JC, Viera AJ, Taylor JM, Mack CP
The Journal of clinical investigation127(2)670-680(2017 Feb)
The smooth muscle-selective RhoGAP GRAF3 is a critical regulator of vascular tone and hypertension.
Bai X, Lenhart KC, Bird KE, Suen AA, Rojas M, Kakoki M, Li F, Smithies O, Mack CP, Taylor JM
Nature communications42910(2013)
GeneRIFs: Gene References Into Functions What's a GeneRIF?
Blood pressure-associated polymorphism controls ARHGAP42 expression via serum response factor DNA binding
Title: Blood pressure-associated polymorphism controls ARHGAP42 expression via serum response factor DNA binding.
GRAF3 is expressed in a smooth muscle-restricted fashion.
Title: The smooth muscle-selective RhoGAP GRAF3 is a critical regulator of vascular tone and hypertension.
The following Arhgap42 gene cDNA ORF clone sequences were retrieved from the NCBI Reference Sequence Database (RefSeq). These sequences represent the protein coding region of the Arhgap42 cDNA ORF which is encoded by the open reading frame (ORF) sequence. ORF sequences can be delivered in our standard vector, pcDNA3.1+/C-(K)DYK or the vector of your choice as an expression/transfection-ready ORF clone. Not the clone you want? Click here to find your clone.
CloneID | OMu90541 | |
Clone ID Related Accession (Same CDS sequence) | NM_001372569.1 | |
Accession Version | NM_001372569.1 Latest version! | Documents for ORF clone product in default vector |
Sequence Information | ORF Nucleotide Sequence (Length: 681bp) Protein sequence SNP |
|
Vector | pcDNA3.1-C-(k)DYK or customized vector | User Manual |
Clone information | Clone Map | MSDS |
Tag on pcDNA3.1+/C-(K)DYK | C terminal DYKDDDDK tags | |
ORF Insert Method | CloneEZ™ Seamless cloning technology | |
Insert Structure | linear | |
Update Date | 2019-09-03 | |
Organism | Mus musculus(house mouse) | |
Product | rho GTPase-activating protein 42 isoform 8 | |
Comment | Comment: VALIDATED REFSEQ: This record has undergone validation or preliminary review. The reference sequence was derived from AC113589.13 and AC160964.1. Sequence Note: The RefSeq transcript and protein were derived from genomic sequence to make the sequence consistent with the reference genome assembly. The genomic coordinates used for the transcript record were based on alignments. ##Evidence-Data-START## Transcript exon combination :: SRR7345562.77700.1, SRR7345562.4901844.1 [ECO:0000332] RNAseq introns :: mixed/partial sample support SAMN00849374, SAMN00849375 [ECO:0000350] ##Evidence-Data-END## |
1 | ATGGGGCTGC CCACTCTGGA GTTCAGCGAT TCGTATTTGG ACAGCCCGGA TTTTAGGGAG |
The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.
RefSeq | NP_001359498.1 |
CDS | 249..929 |
Translation |
Target ORF information:
Target ORF information:
|
NM_001372569.1 |
1 | ATGGGGCTGC CCACTCTGGA GTTCAGCGAT TCGTATTTGG ACAGCCCGGA TTTTAGGGAG |
The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.
CloneID | OMu90544 | |
Clone ID Related Accession (Same CDS sequence) | NM_001372567.1 | |
Accession Version | NM_001372567.1 Latest version! | Documents for ORF clone product in default vector |
Sequence Information | ORF Nucleotide Sequence (Length: 1134bp) Protein sequence SNP |
|
Vector | pcDNA3.1-C-(k)DYK or customized vector | User Manual |
Clone information | Clone Map | MSDS |
Tag on pcDNA3.1+/C-(K)DYK | C terminal DYKDDDDK tags | |
ORF Insert Method | CloneEZ™ Seamless cloning technology | |
Insert Structure | linear | |
Update Date | 2019-09-03 | |
Organism | Mus musculus(house mouse) | |
Product | rho GTPase-activating protein 42 isoform 6 | |
Comment | Comment: VALIDATED REFSEQ: This record has undergone validation or preliminary review. The reference sequence was derived from AC113589.13 and AC160964.1. Sequence Note: The RefSeq transcript and protein were derived from genomic sequence to make the sequence consistent with the reference genome assembly. The genomic coordinates used for the transcript record were based on alignments. ##Evidence-Data-START## Transcript exon combination :: SRR7345562.4720788.1, SRR8865137.8935.1 [ECO:0000332] RNAseq introns :: mixed/partial sample support SAMN00849374, SAMN00849375 [ECO:0000350] ##Evidence-Data-END## |
1 | ATGGGGCTGC CCACTCTGGA GTTCAGCGAT TCGTATTTGG ACAGCCCGGA TTTTAGGGAG |
The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.
RefSeq | NP_001359496.1 |
CDS | 249..1382 |
Translation |
Target ORF information:
Target ORF information:
|
NM_001372567.1 |
1 | ATGGGGCTGC CCACTCTGGA GTTCAGCGAT TCGTATTTGG ACAGCCCGGA TTTTAGGGAG |
The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.
CloneID | OMu90547 | |
Clone ID Related Accession (Same CDS sequence) | NM_001372570.1 | |
Accession Version | NM_001372570.1 Latest version! | Documents for ORF clone product in default vector |
Sequence Information | ORF Nucleotide Sequence (Length: 657bp) Protein sequence SNP |
|
Vector | pcDNA3.1-C-(k)DYK or customized vector | User Manual |
Clone information | Clone Map | MSDS |
Tag on pcDNA3.1+/C-(K)DYK | C terminal DYKDDDDK tags | |
ORF Insert Method | CloneEZ™ Seamless cloning technology | |
Insert Structure | linear | |
Update Date | 2019-09-03 | |
Organism | Mus musculus(house mouse) | |
Product | rho GTPase-activating protein 42 isoform 9 | |
Comment | Comment: VALIDATED REFSEQ: This record has undergone validation or preliminary review. The reference sequence was derived from AC113589.13 and AC160964.1. Sequence Note: The RefSeq transcript and protein were derived from genomic sequence to make the sequence consistent with the reference genome assembly. The genomic coordinates used for the transcript record were based on alignments. ##Evidence-Data-START## Transcript exon combination :: SRR7345562.3997507.1 [ECO:0000332] RNAseq introns :: single sample supports all introns SAMN01164137 [ECO:0000348] ##Evidence-Data-END## |
1 | ATGGGGCTGC CCACTCTGGA GTTCAGCGAT TCGTATTTGG ACAGCCCGGA TTTTAGGGAG |
The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.
RefSeq | NP_001359499.1 |
CDS | 249..905 |
Translation |
Target ORF information:
Target ORF information:
|
NM_001372570.1 |
1 | ATGGGGCTGC CCACTCTGGA GTTCAGCGAT TCGTATTTGG ACAGCCCGGA TTTTAGGGAG |
The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.
CloneID | OMu90548 | |
Clone ID Related Accession (Same CDS sequence) | NM_001372568.1 | |
Accession Version | NM_001372568.1 Latest version! | Documents for ORF clone product in default vector |
Sequence Information | ORF Nucleotide Sequence (Length: 753bp) Protein sequence SNP |
|
Vector | pcDNA3.1-C-(k)DYK or customized vector | User Manual |
Clone information | Clone Map | MSDS |
Tag on pcDNA3.1+/C-(K)DYK | C terminal DYKDDDDK tags | |
ORF Insert Method | CloneEZ™ Seamless cloning technology | |
Insert Structure | linear | |
Update Date | 2019-09-03 | |
Organism | Mus musculus(house mouse) | |
Product | rho GTPase-activating protein 42 isoform 7 | |
Comment | Comment: VALIDATED REFSEQ: This record has undergone validation or preliminary review. The reference sequence was derived from AC113589.13 and AC160964.1. Sequence Note: The RefSeq transcript and protein were derived from genomic sequence to make the sequence consistent with the reference genome assembly. The genomic coordinates used for the transcript record were based on alignments. ##Evidence-Data-START## Transcript exon combination :: SRR7345562.2071396.1, SRR1660815.78760.1 [ECO:0000332] RNAseq introns :: mixed/partial sample support SAMN00849374, SAMN00849375 [ECO:0000350] ##Evidence-Data-END## |
1 | ATGGGGCTGC CCACTCTGGA GTTCAGCGAT TCGTATTTGG ACAGCCCGGA TTTTAGGGAG |
The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.
RefSeq | NP_001359497.1 |
CDS | 249..1001 |
Translation |
Target ORF information:
Target ORF information:
|
NM_001372568.1 |
1 | ATGGGGCTGC CCACTCTGGA GTTCAGCGAT TCGTATTTGG ACAGCCCGGA TTTTAGGGAG |
The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.
CloneID | OMu90707 | |
Clone ID Related Accession (Same CDS sequence) | NM_001372566.1 | |
Accession Version | NM_001372566.1 Latest version! | Documents for ORF clone product in default vector |
Sequence Information | ORF Nucleotide Sequence (Length: 1452bp) Protein sequence SNP |
|
Vector | pcDNA3.1-C-(k)DYK or customized vector | User Manual |
Clone information | Clone Map | MSDS |
Tag on pcDNA3.1+/C-(K)DYK | C terminal DYKDDDDK tags | |
ORF Insert Method | CloneEZ™ Seamless cloning technology | |
Insert Structure | linear | |
Update Date | 2020-01-04 | |
Organism | Mus musculus(house mouse) | |
Product | rho GTPase-activating protein 42 isoform 5 | |
Comment | Comment: VALIDATED REFSEQ: This record has undergone validation or preliminary review. The reference sequence was derived from AC113589.13 and AC160964.1. Sequence Note: The RefSeq transcript and protein were derived from genomic sequence to make the sequence consistent with the reference genome assembly. The genomic coordinates used for the transcript record were based on alignments. ##Evidence-Data-START## Transcript exon combination :: AK082857.1 [ECO:0000332] RNAseq introns :: mixed/partial sample support SAMN00849374, SAMN00849375 [ECO:0000350] ##Evidence-Data-END## |
1 | ATGGGGCTGC CCACTCTGGA GTTCAGCGAT TCGTATTTGG ACAGCCCGGA TTTTAGGGAG |
The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.
RefSeq | NP_001359495.1 |
CDS | 249..1700 |
Translation |
Target ORF information:
Target ORF information:
|
NM_001372566.1 |
1 | ATGGGGCTGC CCACTCTGGA GTTCAGCGAT TCGTATTTGG ACAGCCCGGA TTTTAGGGAG |
The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.
CloneID | OMu04643 | |
Clone ID Related Accession (Same CDS sequence) | NM_027823.1 , NM_027823.2 | |
Accession Version | NM_027823.1 | Documents for ORF clone product in default vector |
Sequence Information | ORF Nucleotide Sequence (Length: 2526bp) Protein sequence SNP |
|
Vector | pcDNA3.1-C-(k)DYK or customized vector | User Manual |
Clone information | Clone Map | MSDS |
Tag on pcDNA3.1+/C-(K)DYK | C terminal DYKDDDDK tags | |
ORF Insert Method | CloneEZ™ Seamless cloning technology | |
Insert Structure | linear | |
Update Date | 2019-02-17 | |
Organism | Mus musculus(house mouse) | |
Product | rho GTPase-activating protein 42 | |
Comment | Comment: PROVISIONAL REFSEQ: This record has not yet been subject to final NCBI review. The reference sequence was derived from BC137892.1. On or before Sep 7, 2008 this sequence version replaced XM_984736.2, XM_146632.7. ##Evidence-Data-START## Transcript exon combination :: BC137892.1, BC137891.1 [ECO:0000332] RNAseq introns :: mixed/partial sample support SAMN00849374, SAMN00849375 [ECO:0000350] ##Evidence-Data-END## |
1 | ATGGGGCTGC CCACTCTGGA GTTCAGCGAT TCGTATTTGG ACAGCCCGGA TTTTAGGGAG |
The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.
RefSeq | NP_082099.1 |
CDS | 235..2760 |
Translation |
Target ORF information:
Target ORF information:
|
NM_027823.1 |
1 | ATGGGGCTGC CCACTCTGGA GTTCAGCGAT TCGTATTTGG ACAGCCCGGA TTTTAGGGAG |
The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.
CloneID | OMu41908 | |
Clone ID Related Accession (Same CDS sequence) | XM_006509884.3 , NM_001372563.1 | |
Accession Version | XM_006509884.3 Latest version! | Documents for ORF clone product in default vector |
Sequence Information | ORF Nucleotide Sequence (Length: 2628bp) Protein sequence SNP |
|
Vector | pcDNA3.1-C-(k)DYK or customized vector | User Manual |
Clone information | Clone Map | MSDS |
Tag on pcDNA3.1+/C-(K)DYK | C terminal DYKDDDDK tags | |
ORF Insert Method | CloneEZ™ Seamless cloning technology | |
Insert Structure | linear | |
Update Date | 2016-06-21 | |
Organism | Mus musculus(house mouse) | |
Product | rho GTPase-activating protein 42 isoform X1 | |
Comment | Comment: MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_000075.6) annotated using gene prediction method: Gnomon, supported by mRNA and EST evidence. Also see: Documentation of NCBI's Annotation Process On Jun 22, 2016 this sequence version replaced XM_006509884.2. ##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Version :: Mus musculus Annotation Release 106 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 7.1 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END## |
1 | ATGGGGCTGC CCACTCTGGA GTTCAGCGAT TCGTATTTGG ACAGCCCGGA TTTTAGGGAG |
The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.
RefSeq | XP_006509947.1 |
CDS | 388..3015 |
Translation |
Target ORF information:
Target ORF information:
|
XM_006509884.3 |
1 | ATGGGGCTGC CCACTCTGGA GTTCAGCGAT TCGTATTTGG ACAGCCCGGA TTTTAGGGAG |
The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.
CloneID | OMu04643 | |
Clone ID Related Accession (Same CDS sequence) | NM_027823.1 , NM_027823.2 | |
Accession Version | NM_027823.2 Latest version! | Documents for ORF clone product in default vector |
Sequence Information | ORF Nucleotide Sequence (Length: 2526bp) Protein sequence SNP |
|
Vector | pcDNA3.1-C-(k)DYK or customized vector | User Manual |
Clone information | Clone Map | MSDS |
Tag on pcDNA3.1+/C-(K)DYK | C terminal DYKDDDDK tags | |
ORF Insert Method | CloneEZ™ Seamless cloning technology | |
Insert Structure | linear | |
Update Date | 2020-01-04 | |
Organism | Mus musculus(house mouse) | |
Product | rho GTPase-activating protein 42 isoform 3 | |
Comment | Comment: VALIDATED REFSEQ: This record has undergone validation or preliminary review. The reference sequence was derived from AC113589.13 and AC160964.1. On Sep 4, 2019 this sequence version replaced NM_027823.1. Sequence Note: The RefSeq transcript and protein were derived from genomic sequence to make the sequence consistent with the reference genome assembly. The genomic coordinates used for the transcript record were based on alignments. ##Evidence-Data-START## Transcript exon combination :: BC137892.1 [ECO:0000332] RNAseq introns :: mixed/partial sample support SAMN00849374, SAMN00849375 [ECO:0000350] ##Evidence-Data-END## |
1 | ATGGGGCTGC CCACTCTGGA GTTCAGCGAT TCGTATTTGG ACAGCCCGGA TTTTAGGGAG |
The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.
RefSeq | NP_082099.1 |
CDS | 249..2774 |
Translation |
Target ORF information:
Target ORF information:
|
NM_027823.2 |
1 | ATGGGGCTGC CCACTCTGGA GTTCAGCGAT TCGTATTTGG ACAGCCCGGA TTTTAGGGAG |
The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.
CloneID | OMu41908 | |
Clone ID Related Accession (Same CDS sequence) | XM_006509884.3 , NM_001372563.1 | |
Accession Version | NM_001372563.1 Latest version! | Documents for ORF clone product in default vector |
Sequence Information | ORF Nucleotide Sequence (Length: 2628bp) Protein sequence SNP |
|
Vector | pcDNA3.1-C-(k)DYK or customized vector | User Manual |
Clone information | Clone Map | MSDS |
Tag on pcDNA3.1+/C-(K)DYK | C terminal DYKDDDDK tags | |
ORF Insert Method | CloneEZ™ Seamless cloning technology | |
Insert Structure | linear | |
Update Date | 2019-09-03 | |
Organism | Mus musculus(house mouse) | |
Product | rho GTPase-activating protein 42 isoform 1 | |
Comment | Comment: VALIDATED REFSEQ: This record has undergone validation or preliminary review. The reference sequence was derived from AC113589.13 and AC160964.1. On Sep 4, 2019 this sequence version replaced XM_006509884.4. Sequence Note: The RefSeq transcript and protein were derived from genomic sequence to make the sequence consistent with the reference genome assembly. The genomic coordinates used for the transcript record were based on alignments. ##Evidence-Data-START## Transcript exon combination :: SRR7345562.2641979.1, SRR7345562.3636057.1 [ECO:0000332] RNAseq introns :: mixed/partial sample support SAMN00849374, SAMN00849375 [ECO:0000350] ##Evidence-Data-END## |
1 | ATGGGGCTGC CCACTCTGGA GTTCAGCGAT TCGTATTTGG ACAGCCCGGA TTTTAGGGAG |
The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.
RefSeq | NP_001359492.1 |
CDS | 249..2876 |
Translation |
Target ORF information:
Target ORF information:
|
NM_001372563.1 |
1 | ATGGGGCTGC CCACTCTGGA GTTCAGCGAT TCGTATTTGG ACAGCCCGGA TTTTAGGGAG |
The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.
CloneID | OMu90542 | |
Clone ID Related Accession (Same CDS sequence) | NM_001372565.1 | |
Accession Version | NM_001372565.1 Latest version! | Documents for ORF clone product in default vector |
Sequence Information | ORF Nucleotide Sequence (Length: 1554bp) Protein sequence SNP |
|
Vector | pcDNA3.1-C-(k)DYK or customized vector | User Manual |
Clone information | Clone Map | MSDS |
Tag on pcDNA3.1+/C-(K)DYK | C terminal DYKDDDDK tags | |
ORF Insert Method | CloneEZ™ Seamless cloning technology | |
Insert Structure | linear | |
Update Date | 2019-09-03 | |
Organism | Mus musculus(house mouse) | |
Product | rho GTPase-activating protein 42 isoform 4 | |
Comment | Comment: VALIDATED REFSEQ: This record has undergone validation or preliminary review. The reference sequence was derived from AC113589.13 and AC160964.1. Sequence Note: The RefSeq transcript and protein were derived from genomic sequence to make the sequence consistent with the reference genome assembly. The genomic coordinates used for the transcript record were based on alignments. ##Evidence-Data-START## Transcript exon combination :: SRR7345562.1911676.1 [ECO:0000332] RNAseq introns :: mixed/partial sample support SAMN00849374, SAMN00849375 [ECO:0000350] ##Evidence-Data-END## |
1 | ATGGGGCTGC CCACTCTGGA GTTCAGCGAT TCGTATTTGG ACAGCCCGGA TTTTAGGGAG |
The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.
RefSeq | NP_001359494.1 |
CDS | 249..1802 |
Translation |
Target ORF information:
Target ORF information:
|
NM_001372565.1 |
1 | ATGGGGCTGC CCACTCTGGA GTTCAGCGAT TCGTATTTGG ACAGCCCGGA TTTTAGGGAG |
The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.
CloneID | OMu90550 | |
Clone ID Related Accession (Same CDS sequence) | NM_001372564.1 | |
Accession Version | NM_001372564.1 Latest version! | Documents for ORF clone product in default vector |
Sequence Information | ORF Nucleotide Sequence (Length: 2565bp) Protein sequence SNP |
|
Vector | pcDNA3.1-C-(k)DYK or customized vector | User Manual |
Clone information | Clone Map | MSDS |
Tag on pcDNA3.1+/C-(K)DYK | C terminal DYKDDDDK tags | |
ORF Insert Method | CloneEZ™ Seamless cloning technology | |
Insert Structure | linear | |
Update Date | 2019-09-03 | |
Organism | Mus musculus(house mouse) | |
Product | rho GTPase-activating protein 42 isoform 2 | |
Comment | Comment: VALIDATED REFSEQ: This record has undergone validation or preliminary review. The reference sequence was derived from AC113589.13 and AC160964.1. Sequence Note: The RefSeq transcript and protein were derived from genomic sequence to make the sequence consistent with the reference genome assembly. The genomic coordinates used for the transcript record were based on alignments. ##Evidence-Data-START## Transcript exon combination :: SRR7345562.2970120.1 [ECO:0000332] RNAseq introns :: mixed/partial sample support SAMN00849374, SAMN00849375 [ECO:0000350] ##Evidence-Data-END## |
1 | ATGGGGCTGC CCACTCTGGA GTTCAGCGAT TCGTATTTGG ACAGCCCGGA TTTTAGGGAG |
The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.
RefSeq | NP_001359493.1 |
CDS | 249..2813 |
Translation |
Target ORF information:
Target ORF information:
|
NM_001372564.1 |
1 | ATGGGGCTGC CCACTCTGGA GTTCAGCGAT TCGTATTTGG ACAGCCCGGA TTTTAGGGAG |
The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.
ARHGAP42 is activated by Src-mediated tyrosine phosphorylation to promote cell motility. |
Blood pressure-associated polymorphism controls ARHGAP42 expression via serum response factor DNA binding. |
The smooth muscle-selective RhoGAP GRAF3 is a critical regulator of vascular tone and hypertension. |