Lypd3 cDNA ORF clone, Mus musculus(house mouse)

Gene
Clones
gRNAs

Gene Symbol	Lypd3
Entrez Gene ID	72434
Full Name	Ly6/Plaur domain containing 3
Synonyms	2310061G07Rik,C4.4a
General protein information	Preferred Names Ly6/Plaur domain containing 3 Names ly6/PLAUR domain-containing protein 3 GPI-anchored metastasis-associated protein C4.4A homolog GPI-anchored metastasis-associated protein homolog
Gene Type	protein-coding
Organism	Mus musculus(house mouse)
Genome	Chromosome: 7 Map Location: 7\|7 A3

mRNA and Protein(s)

mRNA Protein Name

NM_133743.1 NP_598504.1 ly6/PLAUR domain-containing protein 3 precursor
Pathways from BioSystems

mRNA	Protein	Name
NM_133743.1	NP_598504.1	ly6/PLAUR domain-containing protein 3 precursor

Homologies

Homo sapiens (human)	LYPD3	NP_055215.2
	LOC718197	XP_001102229.1
Bos taurus (cattle)	LYPD3	NP_001076888.1
Rattus norvegicus (Norway rat)	Lypd3	NP_068527.1
Canis lupus familiaris (dog)	LYPD3	XP_541585.2
Xenopus tropicalis (tropical clawed frog)	LOC100489124	XP_002939176.2
Pan troglodytes (chimpanzee)	LYPD3	XP_512715.2
Mus musculus (house mouse)	Lypd3	NP_598504.1

Gene Ontology
Bibliography

Related articles in PubMed

Expression of C4.4A in an In Vitro Human Tissue-Engineered Skin Model.
Jacobsen B, Larouche D, Rochette-Drouin O, Ploug M, Germain L
BioMed research international20172403072(2017)

High-throughput discovery of novel developmental phenotypes.
Dickinson ME, Flenniken AM, Ji X, Teboul L, Wong MD, White JK, Meehan TF, Weninger WJ, Westerberg H, Adissu H, Baker CN, Bower L, Brown JM, Caddle LB, Chiani F, Clary D, Cleak J, Daly MJ, Denegre JM, Doe B, Dolan ME, Edie SM, Fuchs H, Gailus-Durner V, Galli A, Gambadoro A, Gallegos J, Guo S, Horner NR, Hsu CW, Johnson SJ, Kalaga S, Keith LC, Lanoue L, Lawson TN, Lek M, Mark M, Marschall S, Mason J, McElwee ML, Newbigging S, Nutter LM, Peterson KA, Ramirez-Solis R, Rowland DJ, Ryder E, Samocha KE, Seavitt JR, Selloum M, Szoke-Kovacs Z, Tamura M, Trainor AG, Tudose I, Wakana S, Warren J, Wendling O, West DB, Wong L, Yoshiki A, , , , , , , , , MacArthur DG, Tocchini-Valentini GP, Gao X, Flicek P, Bradley A, Skarnes WC, Justice MJ, Parkinson HE, Moore M, Wells S, Braun RE, Svenson KL, de Angelis MH, Herault Y, Mohun T, Mallon AM, Henkelman RM, Brown SD, Adams DJ, Lloyd KC, McKerlie C, Beaudet AL, Bu?an M, Murray SA
Nature537(7621)508-514(2016 09)

C4.4A gene ablation is compatible with normal epidermal development and causes modest overt phenotypes.
Kriegbaum MC, Jacobsen B, F?chtbauer A, Hansen GH, Christensen IJ, Rundsten CF, Persson M, Engelholm LH, Madsen AN, Di Meo I, Lund IK, Holst B, Kjaer A, L?rum OD, F?chtbauer EM, Ploug M
Scientific reports625833(2016 May)

Organization, evolution and functions of the human and mouse Ly6/uPAR family genes.
Loughner CL, Bruford EA, McAndrews MS, Delp EE, Swamynathan S, Swamynathan SK
Human genomics1010(2016 Apr)

The International Mouse Phenotyping Consortium Web Portal, a unified point of access for knockout mice and related phenotyping data.
Koscielny G, Yaikhom G, Iyer V, Meehan TF, Morgan H, Atienza-Herrero J, Blake A, Chen CK, Easty R, Di Fenza A, Fiegel T, Grifiths M, Horne A, Karp NA, Kurbatova N, Mason JC, Matthews P, Oakley DJ, Qazi A, Regnart J, Retha A, Santos LA, Sneddon DJ, Warren J, Westerberg H, Wilson RJ, Melvin DG, Smedley D, Brown SD, Flicek P, Skarnes WC, Mallon AM, Parkinson H
Nucleic acids research42(Database issue)D802-9(2014 Jan)

GeneRIFs: Gene References Into Functions What's a GeneRIF?

a possible functional role of C4.4A in early differentiation of stratified squamous epithelia
Title: Expression of C4.4A, a structural uPAR homolog, reflects squamous epithelial differentiation in the adult mouse and during embryogenesis.

The following Lypd3 gene cDNA ORF clone sequences were retrieved from the NCBI Reference Sequence Database (RefSeq). These sequences represent the protein coding region of the Lypd3 cDNA ORF which is encoded by the open reading frame (ORF) sequence. ORF sequences can be delivered in our standard vector, pcDNA3.1⁺/C-(K)DYK or the vector of your choice as an expression/transfection-ready ORF clone. Not the clone you want? Click here to find your clone.

***CloneID	Accession No.	Definition	**Vector	*Turnaround time	Price (USD)	Select
OMu10165	NM_133743.1 Latest version!	Mus musculus Ly6/Plaur domain containing 3 (Lypd3), mRNA.	pcDNA3.1-C-(k)DYK or customized vector	5-7	$188.30 $269.00

ORF Online Only Promotion

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** You may select a custom vector to replace pcDNA3.1+/C-(K)DYK after clone is added to cart.

** GenScript guarantees 100% sequence accuracy of all synthetic DNA constructs we deliver, but we do not guarantee protein expression in your experimental system. Protein expression is influenced by many factors that may vary between experiments or laboratories. In addition, please pay attention to the signal peptide, propeptide and transit peptide in target ORF, which may affect the choice of vector (N/C terminal tag vector).

***One clone ID might be correlated to multiple accession numbers, which share the same CDS sequence.

Reference Sequences (Refseq)

Lypd3 ( NM_133743.1 ) cDNA ORF clone, Mus musculus(house mouse) -> NP_598504.1 Mus musculus Ly6/Plaur domain containing 3 (Lypd3), mRNA.

Price & Availability↑

CloneID	OMu10165
Clone ID Related Accession (Same CDS sequence)	NM_133743.1
Accession Version	NM_133743.1 Latest version!	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 1092bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2019-12-24
Organism	Mus musculus(house mouse)
Product	ly6/PLAUR domain-containing protein 3 precursor
Comment	Comment: PROVISIONAL REFSEQ: This record has not yet been subject to final NCBI review. The reference sequence was derived from BC016549.1. ##Evidence-Data-START## Transcript exon combination :: BC016549.1, AK009998.1 [ECO:0000332] RNAseq introns :: single sample supports all introns SAMN00849375, SAMN00849376 [ECO:0000348] ##Evidence-Data-END##

ATGGATGCCG CCAGGAGAGG AGATACACAG CCAGTGATGT GGACCACCGG ATGGCTGTTG 
CTGCTGCCGC TTCTGCTGTG TGAAGGAGCG CAAGCCCTGG AGTGCTACAG CTGCGTGCAG 
AAGGCGGACG ATGGATGCTC TCCGCACAGG ATGAAGACAG TCAAATGTGG TCCCGGGGTG 
GACGTCTGTA CCGAGGCCGT GGGAGCGGTA GAGACCATCC ACGGGCAATT CTCTGTGGCG 
GTGCGGGGCT GCGGTTCCGG AATCCCGGGC AAGAACGACC GCGGACTGGA CCTTCACGGG 
CTCCTGGCCT TCTTTCAGCT ACAGCAGTGC TCCGAGGACC GATGCAACGC CAAACTCAAC 
CTCACTTTGC GAGGCCTCAA CCCTGCAGGC AATGAGAGTG CATATGAGCC TAACGGTGCA 
GAGTGCTACA GCTGTGTGGG TCTGAGCCGC GAGAAGTGCC AGGGCTCCAT GCCGCCGGTC 
GTGAACTGCT ACAACGCCAG TGGCCGTGTC TACAAGGGCT GCTTCGATGG TAACGTCACC 
CTGACGGCAG CCAACGTGAC CGTGTCCTTA CCTGTCCGAG GCTGCGTCCA GGACGAGACC 
TGCACCCGGG ATGGGGTGAC GGGTCCAGGA TTCACACTCA GCGGCTCTTG CTGTCAGGGC 
CCCCGCTGTA ACGCCGACCT TCGCAACAAG ACCTATTTCT CCCCTCGAAT CCCACCCCTA 
GTCCTGCTGC CCCCTCCAAC CACCGCAGCC CCATCCACTC GGGCCCAGAA CTCCTCCAGC 
ACGACCTCTA CAGCAGCCCC AACCACGACC ACCTCCATCA TCAAGCCCAC CACAGCCCAA 
GCCAGCCACA CTTCTCCCCA TGAAATGGAT CTCGAAGTCA TACAGGAAGA GGGGGCGTCG 
TTGAGTGGAG GTGCTGCGGG CCATGGAGGT ACTGCGGGCC ATGGAGGTGC TGCGGGCCAC 
CAAGACCGCA GCAATATGGA GAAGTATCCA GGAAAGGGTG GGGCCCAGAT CCCAGCTAAA 
GGAGGCTCTG GCACTCTAGG GTCCTGGTTG TCTGCAGTTC TGTTGACTGT GGTTGCTGGC 
GCGATGCTGT GA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	NP_598504.1
CDS	21..1112
Translation	MDAARRGDTQPVMWTTGWLLLLPLLLCEGAQALECYSCVQKADDGCSPHRMKTVKCGPGVDVCTEAVGAVETIHGQFSVAVRGCGSGIPGKNDRGLDLHGLLAFFQLQQCSEDRCNAKLNLTLRGLNPAGNESAYEPNGAECYSCVGLSREKCQGSMPPVVNCYNASGRVYKGCFDGNVTLTAANVTVSLPVRGCVQDETCTRDGVTGPGFTLSGSCCQGPRCNADLRNKTYFSPRIPPLVLLPPPTTAAPSTRAQNSSSTTSTAAPTTTTSIIKPTTAQASHTSPHEMDLEVIQEEGASLSGGAAGHGGTAGHGGAAGHQDRSNMEKYPGKGGAQIPAKGGSGTLGSWLSAVLLTVVAGAML

Target ORF information:

RefSeq Version	NM_133743.1
Organism	Mus musculus(house mouse)
Definition	Mus musculus Ly6/Plaur domain containing 3 (Lypd3), mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

NM_133743.1

ORF Insert Sequence:

ATGGATGCCG CCAGGAGAGG AGATACACAG CCAGTGATGT GGACCACCGG ATGGCTGTTG 
CTGCTGCCGC TTCTGCTGTG TGAAGGAGCG CAAGCCCTGG AGTGCTACAG CTGCGTGCAG 
AAGGCGGACG ATGGATGCTC TCCGCACAGG ATGAAGACAG TCAAATGTGG TCCCGGGGTG 
GACGTCTGTA CCGAGGCCGT GGGAGCGGTA GAGACCATCC ACGGGCAATT CTCTGTGGCG 
GTGCGGGGCT GCGGTTCCGG AATCCCGGGC AAGAACGACC GCGGACTGGA CCTTCACGGG 
CTCCTGGCCT TCTTTCAGCT ACAGCAGTGC TCCGAGGACC GATGCAACGC CAAACTCAAC 
CTCACTTTGC GAGGCCTCAA CCCTGCAGGC AATGAGAGTG CATATGAGCC TAACGGTGCA 
GAGTGCTACA GCTGTGTGGG TCTGAGCCGC GAGAAGTGCC AGGGCTCCAT GCCGCCGGTC 
GTGAACTGCT ACAACGCCAG TGGCCGTGTC TACAAGGGCT GCTTCGATGG TAACGTCACC 
CTGACGGCAG CCAACGTGAC CGTGTCCTTA CCTGTCCGAG GCTGCGTCCA GGACGAGACC 
TGCACCCGGG ATGGGGTGAC GGGTCCAGGA TTCACACTCA GCGGCTCTTG CTGTCAGGGC 
CCCCGCTGTA ACGCCGACCT TCGCAACAAG ACCTATTTCT CCCCTCGAAT CCCACCCCTA 
GTCCTGCTGC CCCCTCCAAC CACCGCAGCC CCATCCACTC GGGCCCAGAA CTCCTCCAGC 
ACGACCTCTA CAGCAGCCCC AACCACGACC ACCTCCATCA TCAAGCCCAC CACAGCCCAA 
GCCAGCCACA CTTCTCCCCA TGAAATGGAT CTCGAAGTCA TACAGGAAGA GGGGGCGTCG 
TTGAGTGGAG GTGCTGCGGG CCATGGAGGT ACTGCGGGCC ATGGAGGTGC TGCGGGCCAC 
CAAGACCGCA GCAATATGGA GAAGTATCCA GGAAAGGGTG GGGCCCAGAT CCCAGCTAAA 
GGAGGCTCTG GCACTCTAGG GTCCTGGTTG TCTGCAGTTC TGTTGACTGT GGTTGCTGGC 
GCGATGCTGT GA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

PubMed

Expression of C4.4A in an In Vitro Human Tissue-Engineered Skin Model.
BioMed research international20172403072(2017)
Jacobsen B,Larouche D,Rochette-Drouin O,Ploug M,Germain L

High-throughput discovery of novel developmental phenotypes.
Nature537(7621)508-514(2016 09)
Dickinson ME,Flenniken AM,Ji X,Teboul L,Wong MD,White JK,Meehan TF,Weninger WJ,Westerberg H,Adissu H,Baker CN,Bower L,Brown JM,Caddle LB,Chiani F,Clary D,Cleak J,Daly MJ,Denegre JM,Doe B,Dolan ME,Edie SM,Fuchs H,Gailus-Durner V,Galli A,Gambadoro A,Gallegos J,Guo S,Horner NR,Hsu CW,Johnson SJ,Kalaga S,Keith LC,Lanoue L,Lawson TN,Lek M,Mark M,Marschall S,Mason J,McElwee ML,Newbigging S,Nutter LM,Peterson KA,Ramirez-Solis R,Rowland DJ,Ryder E,Samocha KE,Seavitt JR,Selloum M,Szoke-Kovacs Z,Tamura M,Trainor AG,Tudose I,Wakana S,Warren J,Wendling O,West DB,Wong L,Yoshiki A,,,,,,,,,MacArthur DG,Tocchini-Valentini GP,Gao X,Flicek P,Bradley A,Skarnes WC,Justice MJ,Parkinson HE,Moore M,Wells S,Braun RE,Svenson KL,de Angelis MH,Herault Y,Mohun T,Mallon AM,Henkelman RM,Brown SD,Adams DJ,Lloyd KC,McKerlie C,Beaudet AL,Bu?an M,Murray SA

C4.4A gene ablation is compatible with normal epidermal development and causes modest overt phenotypes.
Scientific reports625833(2016 May)
Kriegbaum MC,Jacobsen B,F?chtbauer A,Hansen GH,Christensen IJ,Rundsten CF,Persson M,Engelholm LH,Madsen AN,Di Meo I,Lund IK,Holst B,Kjaer A,L?rum OD,F?chtbauer EM,Ploug M

Organization, evolution and functions of the human and mouse Ly6/uPAR family genes.
Human genomics1010(2016 Apr)
Loughner CL,Bruford EA,McAndrews MS,Delp EE,Swamynathan S,Swamynathan SK

The International Mouse Phenotyping Consortium Web Portal, a unified point of access for knockout mice and related phenotyping data.
Nucleic acids research42(Database issue)D802-9(2014 Jan)
Koscielny G,Yaikhom G,Iyer V,Meehan TF,Morgan H,Atienza-Herrero J,Blake A,Chen CK,Easty R,Di Fenza A,Fiegel T,Grifiths M,Horne A,Karp NA,Kurbatova N,Mason JC,Matthews P,Oakley DJ,Qazi A,Regnart J,Retha A,Santos LA,Sneddon DJ,Warren J,Westerberg H,Wilson RJ,Melvin DG,Smedley D,Brown SD,Flicek P,Skarnes WC,Mallon AM,Parkinson H

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Lypd3 cDNA ORF clone, Mus musculus(house mouse)

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Related articles in PubMed

Target ORF information:

Target ORF information:

ORF Insert Sequence:

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