Gene Symbol | Rnf19b |
Entrez Gene ID | 75234 |
Full Name | ring finger protein 19B |
Synonyms | 4930534K13Rik,4930555L03Rik,Ibrdc3 |
General protein information |
|
Gene Type | protein-coding |
Organism | Mus musculus(house mouse) |
Genome |
ORF » Species Summary » Mus musculus » Rnf19b cDNA ORF clone
gRNAs
Gene Symbol | Rnf19b |
Entrez Gene ID | 75234 |
Full Name | ring finger protein 19B |
Synonyms | 4930534K13Rik,4930555L03Rik,Ibrdc3 |
General protein information |
|
Gene Type | protein-coding |
Organism | Mus musculus(house mouse) |
Genome |
mRNA | Protein | Name |
---|---|---|
NM_001368763.1 | NP_001355692.1 | E3 ubiquitin-protein ligase RNF19B isoform 1 |
NM_029219.2 | NP_083495.1 | E3 ubiquitin-protein ligase RNF19B isoform 2 |
XM_006503458.3 | XP_006503521.1 | E3 ubiquitin-protein ligase RNF19B isoform X1 |
NM_029219.1 | NP_083495.1 | E3 ubiquitin-protein ligase RNF19B |
Mus musculus (house mouse) | Rnf19b | NP_083495.1 |
Pan troglodytes (chimpanzee) | RNF19B | XP_001164659.2 |
Canis lupus familiaris (dog) | RNF19B | XP_535322.4 |
Gallus gallus (chicken) | RNF19B | XP_417816.4 |
Homo sapiens (human) | RNF19B | NP_699172.2 |
Bos taurus (cattle) | RNF19B | NP_001192591.1 |
Danio rerio (zebrafish) | rnf19b | NP_001189369.1 |
Xenopus tropicalis (tropical clawed frog) | rnf19b | XP_002940071.2 |
E3 ubiquitin ligase NKLAM positively regulates macrophage inducible nitric oxide synthase expression.
Lawrence DW, Gullickson G, Kornbluth J
Immunobiology220(1)83-92(2015 Jan)
E3 ubiquitin ligase NKLAM is a macrophage phagosome protein and plays a role in bacterial killing.
Lawrence DW, Kornbluth J
Cellular immunology279(1)46-52(2012 Sep)
Impaired NK cytolytic activity and enhanced tumor growth in NK lytic-associated molecule-deficient mice.
Hoover RG, Gullickson G, Kornbluth J
Journal of immunology (Baltimore, Md. : 1950)183(11)6913-21(2009 Dec)
GeneRIFs: Gene References Into Functions What's a GeneRIF?
E3 ubiquitin ligase NKLAM positively regulates macrophage inducible nitric oxide synthase expression.
Title: E3 ubiquitin ligase NKLAM positively regulates macrophage inducible nitric oxide synthase expression.
Data show that Natural Killer Lytic-Associated Molecule (NKLAM) is a component of macrophage phagosomes and is involved in macrophage bactericidal functions.
Title: E3 ubiquitin ligase NKLAM is a macrophage phagosome protein and plays a role in bacterial killing.
support the role for NKLAM in NK function both in vitro and in vivo.
Title: Impaired NK cytolytic activity and enhanced tumor growth in NK lytic-associated molecule-deficient mice.
The following Rnf19b gene cDNA ORF clone sequences were retrieved from the NCBI Reference Sequence Database (RefSeq). These sequences represent the protein coding region of the Rnf19b cDNA ORF which is encoded by the open reading frame (ORF) sequence. ORF sequences can be delivered in our standard vector, pcDNA3.1+/C-(K)DYK or the vector of your choice as an expression/transfection-ready ORF clone. Not the clone you want? Click here to find your clone.
CloneID | OMu06643 | |
Clone ID Related Accession (Same CDS sequence) | NM_029219.2 , NM_029219.1 | |
Accession Version | NM_029219.2 Latest version! | Documents for ORF clone product in default vector |
Sequence Information | ORF Nucleotide Sequence (Length: 2196bp) Protein sequence SNP |
|
Vector | pcDNA3.1-C-(k)DYK or customized vector | ![]() |
Clone information | Clone Map | ![]() |
Tag on pcDNA3.1+/C-(K)DYK | C terminal DYKDDDDK tags | |
ORF Insert Method | CloneEZ™ Seamless cloning technology | |
Insert Structure | linear | |
Update Date | 2020-01-01 | |
Organism | Mus musculus(house mouse) | |
Product | E3 ubiquitin-protein ligase RNF19B isoform 2 | |
Comment | Comment: VALIDATED REFSEQ: This record has undergone validation or preliminary review. The reference sequence was derived from AL606977.28. On Feb 25, 2019 this sequence version replaced NM_029219.1. Sequence Note: The RefSeq transcript and protein were derived from genomic sequence to make the sequence consistent with the reference genome assembly. The genomic coordinates used for the transcript record were based on alignments. ##Evidence-Data-START## Transcript exon combination :: SRR7652917.339223.1, SRR7652917.256960.1 [ECO:0000332] RNAseq introns :: single sample supports all introns SAMN00849374, SAMN00849375 [ECO:0000348] ##Evidence-Data-END## |
1 | ATGGGCTCCG AGAAGGACTC CGAGTCGCCG CGCTCCACCT CGCTCCATGC GGCCGCCCCC |
The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.
RefSeq | NP_083495.1 |
CDS | 128..2323 |
Translation |
Target ORF information:
Target ORF information:
|
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1 | ATGGGCTCCG AGAAGGACTC CGAGTCGCCG CGCTCCACCT CGCTCCATGC GGCCGCCCCC |
The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.
CloneID | OMu06643 | |
Clone ID Related Accession (Same CDS sequence) | NM_029219.2 , NM_029219.1 | |
Accession Version | NM_029219.1 | Documents for ORF clone product in default vector |
Sequence Information | ORF Nucleotide Sequence (Length: 2196bp) Protein sequence SNP |
|
Vector | pcDNA3.1-C-(k)DYK or customized vector | ![]() |
Clone information | Clone Map | ![]() |
Tag on pcDNA3.1+/C-(K)DYK | C terminal DYKDDDDK tags | |
ORF Insert Method | CloneEZ™ Seamless cloning technology | |
Insert Structure | linear | |
Update Date | 2018-07-21 | |
Organism | Mus musculus(house mouse) | |
Product | E3 ubiquitin-protein ligase RNF19B | |
Comment | Comment: VALIDATED REFSEQ: This record has undergone validation or preliminary review. The reference sequence was derived from AL606977.28. On or before Jul 8, 2009 this sequence version replaced XM_910375.2, XM_204030.6. Sequence Note: The RefSeq transcript and protein were derived from genomic sequence to make the sequence consistent with the reference genome assembly. The genomic coordinates used for the transcript record were based on alignments. ##Evidence-Data-START## RNAseq introns :: single sample supports all introns SAMN00849374, SAMN00849375 [ECO:0000348] ##Evidence-Data-END## |
1 | ATGGGCTCCG AGAAGGACTC CGAGTCGCCG CGCTCCACCT CGCTCCATGC GGCCGCCCCC |
The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.
RefSeq | NP_083495.1 |
CDS | 1..2196 |
Translation |
Target ORF information:
Target ORF information:
|
![]() |
1 | ATGGGCTCCG AGAAGGACTC CGAGTCGCCG CGCTCCACCT CGCTCCATGC GGCCGCCCCC |
The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.
CloneID | OMu33858 | |
Clone ID Related Accession (Same CDS sequence) | NM_001368763.1 , XM_006503458.3 | |
Accession Version | NM_001368763.1 Latest version! | Documents for ORF clone product in default vector |
Sequence Information | ORF Nucleotide Sequence (Length: 2199bp) Protein sequence SNP |
|
Vector | pcDNA3.1-C-(k)DYK or customized vector | ![]() |
Clone information | Clone Map | ![]() |
Tag on pcDNA3.1+/C-(K)DYK | C terminal DYKDDDDK tags | |
ORF Insert Method | CloneEZ™ Seamless cloning technology | |
Insert Structure | linear | |
Update Date | 2020-01-01 | |
Organism | Mus musculus(house mouse) | |
Product | E3 ubiquitin-protein ligase RNF19B isoform 1 | |
Comment | Comment: VALIDATED REFSEQ: This record has undergone validation or preliminary review. The reference sequence was derived from AL606977.28. On Feb 25, 2019 this sequence version replaced XM_006503458.3. Sequence Note: The RefSeq transcript and protein were derived from genomic sequence to make the sequence consistent with the reference genome assembly. The genomic coordinates used for the transcript record were based on alignments. ##Evidence-Data-START## Transcript exon combination :: SRR7345562.4751644.1, SRR6238556.3630335.1 [ECO:0000332] RNAseq introns :: single sample supports all introns SAMN00849374, SAMN00849375 [ECO:0000348] ##Evidence-Data-END## |
1 | ATGGGCTCCG AGAAGGACTC CGAGTCGCCG CGCTCCACCT CGCTCCATGC GGCCGCCCCC |
The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.
RefSeq | NP_001355692.1 |
CDS | 128..2326 |
Translation |
Target ORF information:
Target ORF information:
|
![]() |
1 | ATGGGCTCCG AGAAGGACTC CGAGTCGCCG CGCTCCACCT CGCTCCATGC GGCCGCCCCC |
The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.
CloneID | OMu33858 | |
Clone ID Related Accession (Same CDS sequence) | NM_001368763.1 , XM_006503458.3 | |
Accession Version | XM_006503458.3 Latest version! | Documents for ORF clone product in default vector |
Sequence Information | ORF Nucleotide Sequence (Length: 2199bp) Protein sequence SNP |
|
Vector | pcDNA3.1-C-(k)DYK or customized vector | ![]() |
Clone information | Clone Map | ![]() |
Tag on pcDNA3.1+/C-(K)DYK | C terminal DYKDDDDK tags | |
ORF Insert Method | CloneEZ™ Seamless cloning technology | |
Insert Structure | linear | |
Update Date | 2016-06-21 | |
Organism | Mus musculus(house mouse) | |
Product | E3 ubiquitin-protein ligase RNF19B isoform X1 | |
Comment | Comment: MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_000070.6) annotated using gene prediction method: Gnomon, supported by mRNA and EST evidence. Also see: Documentation of NCBI's Annotation Process On Jun 22, 2016 this sequence version replaced XM_006503458.2. ##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Version :: Mus musculus Annotation Release 106 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 7.1 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END## |
1 | ATGGGCTCCG AGAAGGACTC CGAGTCGCCG CGCTCCACCT CGCTCCATGC GGCCGCCCCC |
The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.
RefSeq | XP_006503521.1 |
CDS | 126..2324 |
Translation |
Target ORF information:
Target ORF information:
|
![]() |
1 | ATGGGCTCCG AGAAGGACTC CGAGTCGCCG CGCTCCACCT CGCTCCATGC GGCCGCCCCC |
The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.
E3 ubiquitin ligase NKLAM positively regulates macrophage inducible nitric oxide synthase expression. |
E3 ubiquitin ligase NKLAM is a macrophage phagosome protein and plays a role in bacterial killing. |
Impaired NK cytolytic activity and enhanced tumor growth in NK lytic-associated molecule-deficient mice. |