Gene Symbol | Dtl |
Entrez Gene ID | 76843 |
Full Name | denticleless E3 ubiquitin protein ligase |
Synonyms | 2810047L02Rik,5730564G15Rik,L2dtl,Ramp |
General protein information |
|
Gene Type | protein-coding |
Organism | Mus musculus(house mouse) |
Genome |
ORF » Species Summary » Mus musculus » Dtl cDNA ORF clone
Gene Symbol | Dtl |
Entrez Gene ID | 76843 |
Full Name | denticleless E3 ubiquitin protein ligase |
Synonyms | 2810047L02Rik,5730564G15Rik,L2dtl,Ramp |
General protein information |
|
Gene Type | protein-coding |
Organism | Mus musculus(house mouse) |
Genome |
mRNA | Protein | Name |
---|---|---|
NM_029766.3 | NP_084042.1 | denticleless protein homolog isoform 1 |
NM_001305233.1 | NP_001292162.1 | denticleless protein homolog isoform 2 |
XM_011238925.1 | XP_011237227.1 | denticleless protein homolog isoform X1 |
DTL | XP_001108416.1 | |
Mus musculus (house mouse) | Dtl | NP_084042.1 |
Homo sapiens (human) | DTL | NP_057532.3 |
Bos taurus (cattle) | DTL | XP_003587156.1 |
Danio rerio (zebrafish) | dtl | NP_775348.1 |
Canis lupus familiaris (dog) | DTL | XP_547399.2 |
Rattus norvegicus (Norway rat) | Dtl | XP_223074.5 |
Xenopus tropicalis (tropical clawed frog) | dtl | NP_989402.1 |
Pan troglodytes (chimpanzee) | DTL | XP_525058.3 |
Gallus gallus (chicken) | DTL | NP_001026219.1 |
Maternal DCAF2 is crucial for maintenance of genome stability during the first cell cycle in mice.
Xu YW, Cao LR, Wang M, Xu Y, Wu X, Liu J, Tong C, Fan HY
Journal of cell science130(19)3297-3307(2017 Oct)
Cellular heterogeneity in the ureteric progenitor niche and distinct profiles of branching morphogenesis in organ development.
Rutledge EA, Benazet JD, McMahon AP
Development (Cambridge, England)144(17)3177-3188(2017 09)
High-throughput discovery of novel developmental phenotypes.
Dickinson ME, Flenniken AM, Ji X, Teboul L, Wong MD, White JK, Meehan TF, Weninger WJ, Westerberg H, Adissu H, Baker CN, Bower L, Brown JM, Caddle LB, Chiani F, Clary D, Cleak J, Daly MJ, Denegre JM, Doe B, Dolan ME, Edie SM, Fuchs H, Gailus-Durner V, Galli A, Gambadoro A, Gallegos J, Guo S, Horner NR, Hsu CW, Johnson SJ, Kalaga S, Keith LC, Lanoue L, Lawson TN, Lek M, Mark M, Marschall S, Mason J, McElwee ML, Newbigging S, Nutter LM, Peterson KA, Ramirez-Solis R, Rowland DJ, Ryder E, Samocha KE, Seavitt JR, Selloum M, Szoke-Kovacs Z, Tamura M, Trainor AG, Tudose I, Wakana S, Warren J, Wendling O, West DB, Wong L, Yoshiki A, , , , , , , , , MacArthur DG, Tocchini-Valentini GP, Gao X, Flicek P, Bradley A, Skarnes WC, Justice MJ, Parkinson HE, Moore M, Wells S, Braun RE, Svenson KL, de Angelis MH, Herault Y, Mohun T, Mallon AM, Henkelman RM, Brown SD, Adams DJ, Lloyd KC, McKerlie C, Beaudet AL, Bu?an M, Murray SA
Nature537(7621)508-514(2016 09)
GeneRIFs: Gene References Into Functions What's a GeneRIF?
while interaction with PCNA was important for targeting p21 to the CRL4Cdt2 ligase re-localized to MVM replication centers
Title: Efficient parvovirus replication requires CRL4Cdt2-targeted depletion of p21 to prevent its inhibitory interaction with PCNA.
L2dtl gene expression is essential for very early mouse embryonic development
Title: L2dtl is essential for cell survival and nuclear division in early mouse embryonic development.
The following Dtl gene cDNA ORF clone sequences were retrieved from the NCBI Reference Sequence Database (RefSeq). These sequences represent the protein coding region of the Dtl cDNA ORF which is encoded by the open reading frame (ORF) sequence. ORF sequences can be delivered in our standard vector, pcDNA3.1+/C-(K)DYK or the vector of your choice as an expression/transfection-ready ORF clone. Not the clone you want? Click here to find your clone.
CloneID | OMu71575 | |
Clone ID Related Accession (Same CDS sequence) | XM_011238925.1 | |
Accession Version | XM_011238925.1 Latest version! | Documents for ORF clone product in default vector |
Sequence Information | ORF Nucleotide Sequence (Length: 1695bp) Protein sequence SNP |
|
Vector | pcDNA3.1-C-(k)DYK or customized vector | User Manual |
Clone information | Clone Map | MSDS |
Tag on pcDNA3.1+/C-(K)DYK | C terminal DYKDDDDK tags | |
ORF Insert Method | CloneEZ™ Seamless cloning technology | |
Insert Structure | linear | |
Update Date | 2019-08-07 | |
Organism | Mus musculus(house mouse) | |
Product | denticleless protein homolog isoform X1 | |
Comment | Comment: MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_000067.6) annotated using gene prediction method: Gnomon, supported by EST evidence. Also see: Documentation of NCBI's Annotation Process ##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Name :: Mus musculus Annotation Release 108 Annotation Version :: 108 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 8.2 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END## |
1 | ATGATCTGGG ACACCAGGTG TAACAAAAAA GATGGATTTT ATAGACAAGT GAATCAAATC |
The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.
RefSeq | XP_011237227.1 |
CDS | 610..2304 |
Translation |
Target ORF information:
Target ORF information:
|
XM_011238925.1 |
1 | ATGATCTGGG ACACCAGGTG TAACAAAAAA GATGGATTTT ATAGACAAGT GAATCAAATC |
The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.
CloneID | OMu71576 | |
Clone ID Related Accession (Same CDS sequence) | NM_001305233.1 | |
Accession Version | NM_001305233.1 Latest version! | Documents for ORF clone product in default vector |
Sequence Information | ORF Nucleotide Sequence (Length: 1818bp) Protein sequence SNP |
|
Vector | pcDNA3.1-C-(k)DYK or customized vector | User Manual |
Clone information | Clone Map | MSDS |
Tag on pcDNA3.1+/C-(K)DYK | C terminal DYKDDDDK tags | |
ORF Insert Method | CloneEZ™ Seamless cloning technology | |
Insert Structure | linear | |
Update Date | 2019-10-22 | |
Organism | Mus musculus(house mouse) | |
Product | denticleless protein homolog isoform 2 | |
Comment | Comment: VALIDATED REFSEQ: This record has undergone validation or preliminary review. The reference sequence was derived from BB841951.1, AK054412.1, AC132830.12 and AK133177.1. On Mar 5, 2015 this sequence version replaced XM_006497212.1. Transcript Variant: This variant (2) differs in the 5' UTR, initiates translation at an alternate start codon, and uses an alternate exon in the 5' coding region compared to variant 1. The encoded isoform (2) has a distinct N-terminus and is shorter than isoform 1. Sequence Note: This RefSeq record was created from transcript and genomic sequence data because no single transcript from the reference strain was available for the full length of the gene. The extent of this transcript is supported by transcript alignments. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Gene record to access additional publications. ##Evidence-Data-START## Transcript exon combination :: AK154594.1 [ECO:0000332] RNAseq introns :: single sample supports all introns SAMN01164140, SAMN01164142 [ECO:0000348] ##Evidence-Data-END## COMPLETENESS: complete on the 3' end. |
1 | ATGCAAAGGC CACCAGTGCA GCCTCAAGTC TGTAGCCTTT CCCAAGTTTC AAAAAGCTCA |
The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.
RefSeq | NP_001292162.1 |
CDS | 549..2366 |
Translation |
Target ORF information:
Target ORF information:
|
NM_001305233.1 |
1 | ATGCAAAGGC CACCAGTGCA GCCTCAAGTC TGTAGCCTTT CCCAAGTTTC AAAAAGCTCA |
The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.
CloneID | OMu07440 | |
Clone ID Related Accession (Same CDS sequence) | NM_029766.3 | |
Accession Version | NM_029766.3 Latest version! | Documents for ORF clone product in default vector |
Sequence Information | ORF Nucleotide Sequence (Length: 2190bp) Protein sequence SNP |
|
Vector | pcDNA3.1-C-(k)DYK or customized vector | User Manual |
Clone information | Clone Map | MSDS |
Tag on pcDNA3.1+/C-(K)DYK | C terminal DYKDDDDK tags | |
ORF Insert Method | CloneEZ™ Seamless cloning technology | |
Insert Structure | linear | |
Update Date | 2019-10-22 | |
Organism | Mus musculus(house mouse) | |
Product | denticleless protein homolog isoform 1 | |
Comment | Comment: VALIDATED REFSEQ: This record has undergone validation or preliminary review. The reference sequence was derived from BB841951.1, CF898098.1, AK054412.1, AK133177.1 and AC132830.12. On Mar 5, 2015 this sequence version replaced NM_029766.2. Transcript Variant: This variant (1) encodes the longer isoform (1). Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Gene record to access additional publications. ##Evidence-Data-START## Transcript exon combination :: AK166351.1, AK133177.1 [ECO:0000332] RNAseq introns :: single sample supports all introns SAMN01164137, SAMN01164140 [ECO:0000348] ##Evidence-Data-END## COMPLETENESS: complete on the 3' end. |
1 | ATGCTCTTCA ACTCGGTACT CCGCCAGCCG CAGCTCGGCG TCCTGAGGAA CGGGTGGTCT |
The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.
RefSeq | NP_084042.1 |
CDS | 145..2334 |
Translation |
Target ORF information:
Target ORF information:
|
NM_029766.3 |
1 | ATGCTCTTCA ACTCGGTACT CCGCCAGCCG CAGCTCGGCG TCCTGAGGAA CGGGTGGTCT |
The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.
Maternal DCAF2 is crucial for maintenance of genome stability during the first cell cycle in mice. |
Cellular heterogeneity in the ureteric progenitor niche and distinct profiles of branching morphogenesis in organ development. |
High-throughput discovery of novel developmental phenotypes. |