Gene Symbol | Ston1 |
Entrez Gene ID | 77057 |
Full Name | stonin 1 |
Synonyms | 4921524J06Rik,C86231,Salf,Sblf |
General protein information |
|
Gene Type | protein-coding |
Organism | Mus musculus(house mouse) |
Genome |
ORF » Species Summary » Mus musculus » Ston1 cDNA ORF clone
gRNAs
Gene Symbol | Ston1 |
Entrez Gene ID | 77057 |
Full Name | stonin 1 |
Synonyms | 4921524J06Rik,C86231,Salf,Sblf |
General protein information |
|
Gene Type | protein-coding |
Organism | Mus musculus(house mouse) |
Genome |
mRNA | Protein | Name |
---|---|---|
XM_006525111.2 | XP_006525174.1 | stonin-1 isoform X1 |
XM_006525112.3 | XP_006525175.1 | stonin-1 isoform X1 |
XM_006525111.3 | XP_006525174.1 | stonin-1 isoform X1 |
XM_006525113.2 | XP_006525176.1 | stonin-1 isoform X2 |
NM_029858.2 | NP_084134.2 | stonin-1 |
XM_006525112.4 | XP_006525175.1 | stonin-1 isoform X1 |
XM_006525113.3 | XP_006525176.1 | stonin-1 isoform X2 |
Homo sapiens (human) | STON1 | NP_006864.2 |
Canis lupus familiaris (dog) | STON1 | NP_001191771.1 |
Bos taurus (cattle) | STON1 | NP_001191780.1 |
Rattus norvegicus (Norway rat) | Ston1 | NP_891999.2 |
Mus musculus (house mouse) | Ston1 | NP_084134.2 |
Gallus gallus (chicken) | STON1 | NP_001191794.2 |
Xenopus tropicalis (tropical clawed frog) | ston1 | NP_001191796.1 |
Pan troglodytes (chimpanzee) | STON1 | NP_001191754.1 |
Stonin1 mediates endocytosis of the proteoglycan NG2 and regulates focal adhesion dynamics and cell motility.
Feutlinske F, Browarski M, Ku MC, Trnka P, Waiczies S, Niendorf T, Stallcup WB, Glass R, Krause E, Maritzen T
Nature communications68535(2015 Oct)
A systems approach reveals that the myogenesis genome network is regulated by the transcriptional repressor RP58.
Yokoyama S, Ito Y, Ueno-Kudoh H, Shimizu H, Uchibe K, Albini S, Mitsuoka K, Miyaki S, Kiso M, Nagai A, Hikata T, Osada T, Fukuda N, Yamashita S, Harada D, Mezzano V, Kasai M, Puri PL, Hayashizaki Y, Okado H, Hashimoto M, Asahara H
Developmental cell17(6)836-48(2009 Dec)
Functional dissection of the interactions of stonin 2 with the adaptor complex AP-2 and synaptotagmin.
Walther K, Diril MK, Jung N, Haucke V
Proceedings of the National Academy of Sciences of the United States of America101(4)964-9(2004 Jan)
Human stoned B interacts with AP-2 and synaptotagmin and facilitates clathrin-coated vesicle uncoating.
Walther K, Krauss M, Diril MK, Lemke S, Ricotta D, Honing S, Kaiser S, Haucke V
EMBO reports2(7)634-40(2001 Jul)
GeneRIFs: Gene References Into Functions What's a GeneRIF?
Data establish Stonin1 as a specific adaptor for the endocytosis of NG2 and as an important factor for focal adhesion dynamics and cell migration.
Title: Stonin1 mediates endocytosis of the proteoglycan NG2 and regulates focal adhesion dynamics and cell motility.
The following Ston1 gene cDNA ORF clone sequences were retrieved from the NCBI Reference Sequence Database (RefSeq). These sequences represent the protein coding region of the Ston1 cDNA ORF which is encoded by the open reading frame (ORF) sequence. ORF sequences can be delivered in our standard vector, pcDNA3.1+/C-(K)DYK or the vector of your choice as an expression/transfection-ready ORF clone. Not the clone you want? Click here to find your clone.
CloneID | OMu54164 | |
Clone ID Related Accession (Same CDS sequence) | XM_006525113.2 , XM_006525113.3 | |
Accession Version | XM_006525113.2 | Documents for ORF clone product in default vector |
Sequence Information | ORF Nucleotide Sequence (Length: 1833bp) Protein sequence SNP |
|
Vector | pcDNA3.1-C-(k)DYK or customized vector | ![]() |
Clone information | Clone Map | ![]() |
Tag on pcDNA3.1+/C-(K)DYK | C terminal DYKDDDDK tags | |
ORF Insert Method | CloneEZ™ Seamless cloning technology | |
Insert Structure | linear | |
Update Date | 2016-06-21 | |
Organism | Mus musculus(house mouse) | |
Product | stonin-1 isoform X2 | |
Comment | Comment: MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_000083.6) annotated using gene prediction method: Gnomon, supported by EST evidence. Also see: Documentation of NCBI's Annotation Process On Feb 9, 2015 this sequence version replaced XM_006525113.1. ##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Version :: Mus musculus Annotation Release 106 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 7.1 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END## |
1 | ATGTATTCTA CAAACCCGGG CAGCTGGGTC ACCTTTGATG ATGACCCTGC TTTTCAATCT |
The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.
RefSeq | XP_006525176.1 |
CDS | 155..1987 |
Translation |
Target ORF information:
Target ORF information:
|
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1 | ATGTATTCTA CAAACCCGGG CAGCTGGGTC ACCTTTGATG ATGACCCTGC TTTTCAATCT |
The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.
CloneID | OMu07585 | |
Clone ID Related Accession (Same CDS sequence) | XM_006525111.2 , XM_006525112.3 , XM_006525111.3 , NM_029858.2 , XM_006525112.4 | |
Accession Version | NM_029858.2 Latest version! | Documents for ORF clone product in default vector |
Sequence Information | ORF Nucleotide Sequence (Length: 2193bp) Protein sequence SNP |
|
Vector | pcDNA3.1-C-(k)DYK or customized vector | ![]() |
Clone information | Clone Map | ![]() |
Tag on pcDNA3.1+/C-(K)DYK | C terminal DYKDDDDK tags | |
ORF Insert Method | CloneEZ™ Seamless cloning technology | |
Insert Structure | linear | |
Update Date | 2019-01-20 | |
Organism | Mus musculus(house mouse) | |
Product | stonin-1 | |
Comment | Comment: VALIDATED REFSEQ: This record has undergone validation or preliminary review. The reference sequence was derived from BY334339.1, AK014958.1, CF729405.1 and CD349605.1. On Nov 2, 2007 this sequence version replaced NM_029858.1. ##Evidence-Data-START## Transcript exon combination :: AK014958.1 [ECO:0000332] RNAseq introns :: single sample supports all introns SAMN00849374, SAMN00849375 [ECO:0000348] ##Evidence-Data-END## |
1 | ATGTATTCTA CAAACCCGGG CAGCTGGGTC ACCTTTGATG ATGACCCTGC TTTTCAATCT |
The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.
RefSeq | NP_084134.2 |
CDS | 356..2548 |
Translation |
Target ORF information:
Target ORF information:
|
![]() |
1 | ATGTATTCTA CAAACCCGGG CAGCTGGGTC ACCTTTGATG ATGACCCTGC TTTTCAATCT |
The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.
CloneID | OMu07585 | |
Clone ID Related Accession (Same CDS sequence) | XM_006525111.2 , XM_006525112.3 , XM_006525111.3 , NM_029858.2 , XM_006525112.4 | |
Accession Version | XM_006525111.2 | Documents for ORF clone product in default vector |
Sequence Information | ORF Nucleotide Sequence (Length: 2193bp) Protein sequence SNP |
|
Vector | pcDNA3.1-C-(k)DYK or customized vector | ![]() |
Clone information | Clone Map | ![]() |
Tag on pcDNA3.1+/C-(K)DYK | C terminal DYKDDDDK tags | |
ORF Insert Method | CloneEZ™ Seamless cloning technology | |
Insert Structure | linear | |
Update Date | 2016-06-21 | |
Organism | Mus musculus(house mouse) | |
Product | stonin-1 isoform X1 | |
Comment | Comment: MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_000083.6) annotated using gene prediction method: Gnomon, supported by EST evidence. Also see: Documentation of NCBI's Annotation Process On Feb 9, 2015 this sequence version replaced XM_006525111.1. ##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Version :: Mus musculus Annotation Release 106 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 7.1 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END## |
1 | ATGTATTCTA CAAACCCGGG CAGCTGGGTC ACCTTTGATG ATGACCCTGC TTTTCAATCT |
The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.
RefSeq | XP_006525174.1 |
CDS | 154..2346 |
Translation |
Target ORF information:
Target ORF information:
|
![]() |
1 | ATGTATTCTA CAAACCCGGG CAGCTGGGTC ACCTTTGATG ATGACCCTGC TTTTCAATCT |
The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.
CloneID | OMu07585 | |
Clone ID Related Accession (Same CDS sequence) | XM_006525111.2 , XM_006525112.3 , XM_006525111.3 , NM_029858.2 , XM_006525112.4 | |
Accession Version | XM_006525112.3 | Documents for ORF clone product in default vector |
Sequence Information | ORF Nucleotide Sequence (Length: 2193bp) Protein sequence SNP |
|
Vector | pcDNA3.1-C-(k)DYK or customized vector | ![]() |
Clone information | Clone Map | ![]() |
Tag on pcDNA3.1+/C-(K)DYK | C terminal DYKDDDDK tags | |
ORF Insert Method | CloneEZ™ Seamless cloning technology | |
Insert Structure | linear | |
Update Date | 2016-06-21 | |
Organism | Mus musculus(house mouse) | |
Product | stonin-1 isoform X1 | |
Comment | Comment: MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_000083.6) annotated using gene prediction method: Gnomon, supported by mRNA and EST evidence. Also see: Documentation of NCBI's Annotation Process On Jun 22, 2016 this sequence version replaced XM_006525112.2. ##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Version :: Mus musculus Annotation Release 106 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 7.1 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END## |
1 | ATGTATTCTA CAAACCCGGG CAGCTGGGTC ACCTTTGATG ATGACCCTGC TTTTCAATCT |
The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.
RefSeq | XP_006525175.1 |
CDS | 304..2496 |
Translation |
Target ORF information:
Target ORF information:
|
![]() |
1 | ATGTATTCTA CAAACCCGGG CAGCTGGGTC ACCTTTGATG ATGACCCTGC TTTTCAATCT |
The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.
CloneID | OMu07585 | |
Clone ID Related Accession (Same CDS sequence) | XM_006525111.2 , XM_006525112.3 , XM_006525111.3 , NM_029858.2 , XM_006525112.4 | |
Accession Version | XM_006525111.3 Latest version! | Documents for ORF clone product in default vector |
Sequence Information | ORF Nucleotide Sequence (Length: 2193bp) Protein sequence SNP |
|
Vector | pcDNA3.1-C-(k)DYK or customized vector | ![]() |
Clone information | Clone Map | ![]() |
Tag on pcDNA3.1+/C-(K)DYK | C terminal DYKDDDDK tags | |
ORF Insert Method | CloneEZ™ Seamless cloning technology | |
Insert Structure | linear | |
Update Date | 2019-08-07 | |
Organism | Mus musculus(house mouse) | |
Product | stonin-1 isoform X1 | |
Comment | Comment: MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_000083.6) annotated using gene prediction method: Gnomon, supported by mRNA and EST evidence. Also see: Documentation of NCBI's Annotation Process On Aug 8, 2019 this sequence version replaced XM_006525111.2. ##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Name :: Mus musculus Annotation Release 108 Annotation Version :: 108 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 8.2 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END## |
1 | ATGTATTCTA CAAACCCGGG CAGCTGGGTC ACCTTTGATG ATGACCCTGC TTTTCAATCT |
The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.
RefSeq | XP_006525174.1 |
CDS | 175..2367 |
Translation |
Target ORF information:
Target ORF information:
|
![]() |
1 | ATGTATTCTA CAAACCCGGG CAGCTGGGTC ACCTTTGATG ATGACCCTGC TTTTCAATCT |
The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.
CloneID | OMu07585 | |
Clone ID Related Accession (Same CDS sequence) | XM_006525111.2 , XM_006525112.3 , XM_006525111.3 , NM_029858.2 , XM_006525112.4 | |
Accession Version | XM_006525112.4 Latest version! | Documents for ORF clone product in default vector |
Sequence Information | ORF Nucleotide Sequence (Length: 2193bp) Protein sequence SNP |
|
Vector | pcDNA3.1-C-(k)DYK or customized vector | ![]() |
Clone information | Clone Map | ![]() |
Tag on pcDNA3.1+/C-(K)DYK | C terminal DYKDDDDK tags | |
ORF Insert Method | CloneEZ™ Seamless cloning technology | |
Insert Structure | linear | |
Update Date | 2019-08-07 | |
Organism | Mus musculus(house mouse) | |
Product | stonin-1 isoform X1 | |
Comment | Comment: MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_000083.6) annotated using gene prediction method: Gnomon, supported by mRNA and EST evidence. Also see: Documentation of NCBI's Annotation Process On Aug 8, 2019 this sequence version replaced XM_006525112.3. ##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Name :: Mus musculus Annotation Release 108 Annotation Version :: 108 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 8.2 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END## |
1 | ATGTATTCTA CAAACCCGGG CAGCTGGGTC ACCTTTGATG ATGACCCTGC TTTTCAATCT |
The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.
RefSeq | XP_006525175.1 |
CDS | 303..2495 |
Translation |
Target ORF information:
Target ORF information:
|
![]() |
1 | ATGTATTCTA CAAACCCGGG CAGCTGGGTC ACCTTTGATG ATGACCCTGC TTTTCAATCT |
The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.
CloneID | OMu54164 | |
Clone ID Related Accession (Same CDS sequence) | XM_006525113.2 , XM_006525113.3 | |
Accession Version | XM_006525113.3 Latest version! | Documents for ORF clone product in default vector |
Sequence Information | ORF Nucleotide Sequence (Length: 1833bp) Protein sequence SNP |
|
Vector | pcDNA3.1-C-(k)DYK or customized vector | ![]() |
Clone information | Clone Map | ![]() |
Tag on pcDNA3.1+/C-(K)DYK | C terminal DYKDDDDK tags | |
ORF Insert Method | CloneEZ™ Seamless cloning technology | |
Insert Structure | linear | |
Update Date | 2019-08-07 | |
Organism | Mus musculus(house mouse) | |
Product | stonin-1 isoform X2 | |
Comment | Comment: MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_000083.6) annotated using gene prediction method: Gnomon, supported by mRNA and EST evidence. Also see: Documentation of NCBI's Annotation Process On Aug 8, 2019 this sequence version replaced XM_006525113.2. ##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Name :: Mus musculus Annotation Release 108 Annotation Version :: 108 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 8.2 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END## |
1 | ATGTATTCTA CAAACCCGGG CAGCTGGGTC ACCTTTGATG ATGACCCTGC TTTTCAATCT |
The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.
RefSeq | XP_006525176.1 |
CDS | 175..2007 |
Translation |
Target ORF information:
Target ORF information:
|
![]() |
1 | ATGTATTCTA CAAACCCGGG CAGCTGGGTC ACCTTTGATG ATGACCCTGC TTTTCAATCT |
The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.
Stonin1 mediates endocytosis of the proteoglycan NG2 and regulates focal adhesion dynamics and cell motility. |
A systems approach reveals that the myogenesis genome network is regulated by the transcriptional repressor RP58. |
Functional dissection of the interactions of stonin 2 with the adaptor complex AP-2 and synaptotagmin. |
Human stoned B interacts with AP-2 and synaptotagmin and facilitates clathrin-coated vesicle uncoating. |