Gene Symbol | MLANA |
Entrez Gene ID | 77836 |
Full Name | melan-A |
Synonyms | A930034P04Rik,Mart1 |
General protein information |
|
Gene Type | protein-coding |
Organism | Mus musculus(House mouse) |
Genome |
ORF » Species Summary » Mus musculus » MLANA cDNA ORF clone
Gene Symbol | MLANA |
Entrez Gene ID | 77836 |
Full Name | melan-A |
Synonyms | A930034P04Rik,Mart1 |
General protein information |
|
Gene Type | protein-coding |
Organism | Mus musculus(House mouse) |
Genome |
mRNA | Protein | Name |
---|---|---|
NM_029993.1 | NP_084269.1 | melanoma antigen recognized by T-cells 1 |
XM_011247400.2 | XP_011245702.1 | melanoma antigen recognized by T-cells 1 isoform X1 |
XM_011247400.1 | XP_011245702.1 | melanoma antigen recognized by T-cells 1 isoform X1 |
Homo sapiens (human) | MLANA | NP_005502.1 |
Mus musculus (house mouse) | Mlana | NP_084269.1 |
MLANA | XP_001112920.1 | |
Canis lupus familiaris (dog) | MLANA | NP_001181897.1 |
Rattus norvegicus (Norway rat) | Mlana | NP_001099818.1 |
Bos taurus (cattle) | MLANA | NP_001180064.1 |
Gallus gallus (chicken) | MLANA | XP_001232043.1 |
Pan troglodytes (chimpanzee) | MLANA | XP_001141417.1 |
Effects of Long-term Serial Passaging on the Characteristics and Properties of Cell Lines Derived From Uveal Melanoma Primary Tumors.
Mouriaux F, Zaniolo K, Bergeron MA, Weidmann C, De La Fouchardi?re A, Fournier F, Droit A, Morcos MW, Landreville S, Gu?rin SL
Investigative ophthalmology & visual science57(13)5288-5301(2016 Oct)
Keratin 76 is required for tight junction function and maintenance of the skin barrier.
DiTommaso T, Cottle DL, Pearson HB, Schl?ter H, Kaur P, Humbert PO, Smyth IM
PLoS genetics10(10)e1004706(2014 Oct)
PAX6 regulates melanogenesis in the retinal pigmented epithelium through feed-forward regulatory interactions with MITF.
Raviv S, Bharti K, Rencus-Lazar S, Cohen-Tayar Y, Schyr R, Evantal N, Meshorer E, Zilberberg A, Idelson M, Reubinoff B, Grebe R, Rosin-Arbesfeld R, Lauderdale J, Lutty G, Arnheiter H, Ashery-Padan R
PLoS genetics10(5)e1004360(2014)
Coat color dilution in mice because of inactivation of the melanoma antigen MART-1.
Aydin IT, Hummler E, Smit NP, Beermann F
Pigment cell & melanoma research25(1)37-46(2012 Jan)
A mart-1::Cre transgenic line induces recombination in melanocytes and retinal pigment epithelium.
Aydin IT, Beermann F
Genesis (New York, N.Y. : 2000)49(5)403-9(2011 May)
GeneRIFs: Gene References Into Functions What's a GeneRIF?
Cell passaging severely reduced the expression of genes encoding markers typical of UM, including those of the prognostic gene signature. Marked differences between gene expression profiles of primary tumors and cell lines could be linked to the infiltrating immune and stromal cells in situ.
Title: Effects of Long-term Serial Passaging on the Characteristics and Properties of Cell Lines Derived From Uveal Melanoma Primary Tumors.
MART-1 is a pigmentation gene that is required for melanosome biogenesis and/or maintenance.
Title: Coat color dilution in mice because of inactivation of the melanoma antigen MART-1.
Results suggest that the MART-1::Cre line may serve as a novel and useful tool for functional studies in melanocytes and retinal pigment epithelium.
Title: A mart-1::Cre transgenic line induces recombination in melanocytes and retinal pigment epithelium.
OA1 interacts with MART-1 at early stages of melanogenesis to control melanosome identity and composition.
Title: The ocular albinism type 1 (OA1) G-protein-coupled receptor functions with MART-1 at early stages of melanogenesis to control melanosome identity and composition.
mLANA and p53 have roles in virus replication
Title: ORF73-null murine gammaherpesvirus 68 reveals roles for mLANA and p53 in virus replication.
The following MLANA gene cDNA ORF clone sequences were retrieved from the NCBI Reference Sequence Database (RefSeq). These sequences represent the protein coding region of the MLANA cDNA ORF which is encoded by the open reading frame (ORF) sequence. ORF sequences can be delivered in our standard vector, pcDNA3.1+/C-(K)DYK or the vector of your choice as an expression/transfection-ready ORF clone. Not the clone you want? Click here to find your clone.
CloneID | OMu07797 | |
Clone ID Related Accession (Same CDS sequence) | NM_029993.1 , XM_011247400.2 , XM_011247400.1 | |
Accession Version | NM_029993.1 Latest version! | Documents for ORF clone product in default vector |
Sequence Information | ORF Nucleotide Sequence (Length: 342bp) Protein sequence SNP |
|
Vector | pcDNA3.1-C-(k)DYK or customized vector | User Manual |
Clone information | Clone Map | MSDS |
Tag on pcDNA3.1+/C-(K)DYK | C terminal DYKDDDDK tags | |
ORF Insert Method | CloneEZ™ Seamless cloning technology | |
Insert Structure | linear | |
Update Date | 2018-05-27 | |
Organism | Mus musculus(house mouse) | |
Product | melanoma antigen recognized by T-cells 1 | |
Comment | Comment: PROVISIONAL REFSEQ: This record has not yet been subject to final NCBI review. The reference sequence was derived from BC111114.1. On or before Jul 24, 2006 this sequence version replaced XM_129166.5, XM_916895.2, XM_993504.1. ##Evidence-Data-START## Transcript exon combination :: BC111114.1, BB851876.1 [ECO:0000332] RNAseq introns :: single sample supports all introns SAMN00849375, SAMN00849387 [ECO:0000348] ##Evidence-Data-END## |
1 | ATGCCCCAAG AAGACATTCA CTTTGGTTAT CCCAGGAAGG GGCACAGACG CTCCTATGTC |
The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.
RefSeq | NP_084269.1 |
CDS | 47..388 |
Translation |
Target ORF information:
Target ORF information:
|
NM_029993.1 |
1 | ATGCCCCAAG AAGACATTCA CTTTGGTTAT CCCAGGAAGG GGCACAGACG CTCCTATGTC |
The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.
CloneID | OMu07797 | |
Clone ID Related Accession (Same CDS sequence) | NM_029993.1 , XM_011247400.2 , XM_011247400.1 | |
Accession Version | XM_011247400.2 Latest version! | Documents for ORF clone product in default vector |
Sequence Information | ORF Nucleotide Sequence (Length: 342bp) Protein sequence SNP |
|
Vector | pcDNA3.1-C-(k)DYK or customized vector | User Manual |
Clone information | Clone Map | MSDS |
Tag on pcDNA3.1+/C-(K)DYK | C terminal DYKDDDDK tags | |
ORF Insert Method | CloneEZ™ Seamless cloning technology | |
Insert Structure | linear | |
Update Date | 2019-08-07 | |
Organism | Mus musculus(house mouse) | |
Product | melanoma antigen recognized by T-cells 1 isoform X1 | |
Comment | Comment: MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_000085.6) annotated using gene prediction method: Gnomon, supported by mRNA and EST evidence. Also see: Documentation of NCBI's Annotation Process On Jun 22, 2016 this sequence version replaced XM_011247400.1. ##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Name :: Mus musculus Annotation Release 108 Annotation Version :: 108 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 8.2 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END## |
1 | ATGCCCCAAG AAGACATTCA CTTTGGTTAT CCCAGGAAGG GGCACAGACG CTCCTATGTC |
The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.
RefSeq | XP_011245702.1 |
CDS | 164..505 |
Translation |
Target ORF information:
Target ORF information:
|
XM_011247400.2 |
1 | ATGCCCCAAG AAGACATTCA CTTTGGTTAT CCCAGGAAGG GGCACAGACG CTCCTATGTC |
The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.
CloneID | OMu07797 | |
Clone ID Related Accession (Same CDS sequence) | NM_029993.1 , XM_011247400.2 , XM_011247400.1 | |
Accession Version | XM_011247400.1 | Documents for ORF clone product in default vector |
Sequence Information | ORF Nucleotide Sequence (Length: 342bp) Protein sequence SNP |
|
Vector | pcDNA3.1-C-(k)DYK or customized vector | User Manual |
Clone information | Clone Map | MSDS |
Tag on pcDNA3.1+/C-(K)DYK | C terminal DYKDDDDK tags | |
ORF Insert Method | CloneEZ™ Seamless cloning technology | |
Insert Structure | linear | |
Update Date | 2015-02-08 | |
Organism | Mus musculus(House mouse) | |
Product | melanoma antigen recognized by T-cells 1 isoform X1 | |
Comment |
1 | ATGCCCCAAG AAGACATTCA CTTTGGTTAT CCCAGGAAGG GGCACAGACG CTCCTATGTC |
The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.
RefSeq | XP_011245702.1 |
Translation |
Target ORF information:
Target ORF information:
|
XM_011247400.1 |
1 | ATGCCCCAAG AAGACATTCA CTTTGGTTAT CCCAGGAAGG GGCACAGACG CTCCTATGTC |
The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.
Effects of Long-term Serial Passaging on the Characteristics and Properties of Cell Lines Derived From Uveal Melanoma Primary Tumors. |
Keratin 76 is required for tight junction function and maintenance of the skin barrier. |
PAX6 regulates melanogenesis in the retinal pigmented epithelium through feed-forward regulatory interactions with MITF. |
Coat color dilution in mice because of inactivation of the melanoma antigen MART-1. |
A mart-1::Cre transgenic line induces recombination in melanocytes and retinal pigment epithelium. |