Gene Symbol | Ckap2 |
Entrez Gene ID | 80986 |
Full Name | cytoskeleton associated protein 2 |
Synonyms | AI461656,AW228814,LB1 |
General protein information |
|
Gene Type | protein-coding |
Organism | Mus musculus(house mouse) |
Genome |
ORF » Species Summary » Mus musculus » Ckap2 cDNA ORF clone
gRNAs
Gene Symbol | Ckap2 |
Entrez Gene ID | 80986 |
Full Name | cytoskeleton associated protein 2 |
Synonyms | AI461656,AW228814,LB1 |
General protein information |
|
Gene Type | protein-coding |
Organism | Mus musculus(house mouse) |
Genome |
mRNA | Protein | Name |
---|---|---|
XM_006509226.3 | XP_006509289.1 | cytoskeleton-associated protein 2 isoform X1 |
XM_006509226.4 | XP_006509289.1 | cytoskeleton-associated protein 2 isoform X1 |
NM_001004140.2 | NP_001004140.2 | cytoskeleton-associated protein 2 |
CKAP2 | XP_001084035.1 | |
Rattus norvegicus (Norway rat) | Ckap2 | NP_001162610.1 |
Gallus gallus (chicken) | CKAP2 | NP_001006274.1 |
Danio rerio (zebrafish) | si:ch211-266i6.3 | XP_697274.2 |
Bos taurus (cattle) | CKAP2 | NP_001091501.1 |
Mus musculus (house mouse) | Ckap2 | NP_001004140.2 |
Rattus norvegicus (Norway rat) | LOC691173 | XP_003749023.1 |
Xenopus tropicalis (tropical clawed frog) | ckap2 | XP_002936769.2 |
Homo sapiens (human) | CKAP2 | NP_001091995.1 |
Pan troglodytes (chimpanzee) | CKAP2 | XP_001135710.1 |
Canis lupus familiaris (dog) | CKAP2 | XP_005635452.1 |
CKAP2 phosphorylation by CDK1/cyclinB1 is crucial for maintaining centrosome integrity.
Yoo BH, Kang DS, Park CH, Kang K, Bae CD
Experimental & molecular medicine49(7)e354(2017 Jul)
Lamin-B1 contributes to the proper timing of epicardial cell migration and function during embryonic heart development.
Tran JR, Zheng X, Zheng Y
Molecular biology of the cell27(25)3956-3963(2016 Dec)
CKAP2 is necessary to ensure the faithful spindle bipolarity in a dividing diploid hepatocyte.
Yoo BH, Park CH, Kim HJ, Kang DS, Bae CD
Biochemical and biophysical research communications473(4)886-893(2016 05)
The Interleukin-2-mTORc1 Kinase Axis Defines the Signaling, Differentiation, and Metabolism of T Helper 1 and Follicular B Helper T Cells.
Ray JP, Staron MM, Shyer JA, Ho PC, Marshall HD, Gray SM, Laidlaw BJ, Araki K, Ahmed R, Kaech SM, Craft J
Immunity43(4)690-702(2015 Oct)
Angiogenesis QTL on Mouse Chromosome 8 Colocalizes with Differential ?-Defensin Expression.
Smith J, Liu F, Beyer B, Morales K, Reilly A, Cole R, Herron BJ
Journal of biomolecular techniques : JBT26(2)45-53(2015 Jul)
GeneRIFs: Gene References Into Functions What's a GeneRIF?
we found that Lb1-null epicardial cells have a delayed nuclear morphology change in vivo, suggesting that Lb1 facilitates morphological changes associated with migration. These findings suggest that Lb1 contributes to nuclear shape maintenance and migration of epicardial cells
Title: Lamin-B1 contributes to the proper timing of epicardial cell migration and function during embryonic heart development.
These data suggest a physiological role of CKAP2 in the formation of spindle bipolarity, which is necessary for maintaining chromosomal stability.
Title: CKAP2 is necessary to ensure the faithful spindle bipolarity in a dividing diploid hepatocyte.
Our present findings demonstrate that TMAP/CKAP2 is essential for proper chromosome segregation and for maintaining genomic stability.
Title: TMAP/CKAP2 is essential for proper chromosome segregation.
The cellular functions of TMAP/CKAP2 might be regulated by timely phosphorylation and dephosphorylation during the course of mitosis.
Title: Transient phosphorylation of tumor associated microtubule associated protein (TMAP)/cytoskeleton associated protein 2 (CKAP2) at Thr-596 during early phases of mitosis.
Data suggest the existence of a functional positive feedback loop in which Ckap2 activates the G1 tetraploidy checkpoint and prevents aneuploidy.
Title: Ckap2 regulates aneuploidy, cell cycling, and cell death in a p53-dependent manner.
The following Ckap2 gene cDNA ORF clone sequences were retrieved from the NCBI Reference Sequence Database (RefSeq). These sequences represent the protein coding region of the Ckap2 cDNA ORF which is encoded by the open reading frame (ORF) sequence. ORF sequences can be delivered in our standard vector, pcDNA3.1+/C-(K)DYK or the vector of your choice as an expression/transfection-ready ORF clone. Not the clone you want? Click here to find your clone.
CloneID | OMu40710 | |
Clone ID Related Accession (Same CDS sequence) | XM_006509226.3 , XM_006509226.4 | |
Accession Version | XM_006509226.3 | Documents for ORF clone product in default vector |
Sequence Information | ORF Nucleotide Sequence (Length: 1794bp) Protein sequence SNP |
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Vector | pcDNA3.1-C-(k)DYK or customized vector | ![]() |
Clone information | Clone Map | ![]() |
Tag on pcDNA3.1+/C-(K)DYK | C terminal DYKDDDDK tags | |
ORF Insert Method | CloneEZ™ Seamless cloning technology | |
Insert Structure | linear | |
Update Date | 2016-06-21 | |
Organism | Mus musculus(house mouse) | |
Product | cytoskeleton-associated protein 2 isoform X1 | |
Comment | Comment: MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_000074.6) annotated using gene prediction method: Gnomon, supported by EST evidence. Also see: Documentation of NCBI's Annotation Process On Jun 22, 2016 this sequence version replaced XM_006509226.2. ##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Version :: Mus musculus Annotation Release 106 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 7.1 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END## |
1 | ATGATAACAT CTGAGGATCG GGTCCAAGAA GGGAAAAAAG TTGTGAAACT CAAAACAGAA |
The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.
RefSeq | XP_006509289.1 |
CDS | 238..2031 |
Translation |
Target ORF information:
Target ORF information:
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1 | ATGATAACAT CTGAGGATCG GGTCCAAGAA GGGAAAAAAG TTGTGAAACT CAAAACAGAA |
The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.
CloneID | OMu10590 | |
Clone ID Related Accession (Same CDS sequence) | NM_001004140.2 | |
Accession Version | NM_001004140.2 Latest version! | Documents for ORF clone product in default vector |
Sequence Information | ORF Nucleotide Sequence (Length: 1995bp) Protein sequence SNP |
|
Vector | pcDNA3.1-C-(k)DYK or customized vector | ![]() |
Clone information | Clone Map | ![]() |
Tag on pcDNA3.1+/C-(K)DYK | C terminal DYKDDDDK tags | |
ORF Insert Method | CloneEZ™ Seamless cloning technology | |
Insert Structure | linear | |
Update Date | 2019-09-21 | |
Organism | Mus musculus(house mouse) | |
Product | cytoskeleton-associated protein 2 | |
Comment | Comment: VALIDATED REFSEQ: This record has undergone validation or preliminary review. The reference sequence was derived from AC117665.6, AK132463.1 and BM217153.2. On Nov 20, 2009 this sequence version replaced NM_001004140.1. Sequence Note: This RefSeq record was created from transcript and genomic sequence data to make the sequence consistent with the reference genome assembly. The genomic coordinates used for the transcript record were based on transcript alignments. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Gene record to access additional publications. ##Evidence-Data-START## Transcript exon combination :: AY692438.1, AK132463.1 [ECO:0000332] RNAseq introns :: single sample supports all introns SAMN01164143 [ECO:0000348] ##Evidence-Data-END## |
1 | ATGGCAGAGT CCAGGAAACG CTTCCTTGGC AGGGCTGCGA GGAATCCCTT GCCGGTGACC |
The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.
RefSeq | NP_001004140.2 |
CDS | 28..2022 |
Translation |
Target ORF information:
Target ORF information:
|
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1 | ATGGCAGAGT CCAGGAAACG CTTCCTTGGC AGGGCTGCGA GGAATCCCTT GCCGGTGACC |
The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.
CloneID | OMu40710 | |
Clone ID Related Accession (Same CDS sequence) | XM_006509226.3 , XM_006509226.4 | |
Accession Version | XM_006509226.4 Latest version! | Documents for ORF clone product in default vector |
Sequence Information | ORF Nucleotide Sequence (Length: 1794bp) Protein sequence SNP |
|
Vector | pcDNA3.1-C-(k)DYK or customized vector | ![]() |
Clone information | Clone Map | ![]() |
Tag on pcDNA3.1+/C-(K)DYK | C terminal DYKDDDDK tags | |
ORF Insert Method | CloneEZ™ Seamless cloning technology | |
Insert Structure | linear | |
Update Date | 2019-08-07 | |
Organism | Mus musculus(house mouse) | |
Product | cytoskeleton-associated protein 2 isoform X1 | |
Comment | Comment: MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_000074.6) annotated using gene prediction method: Gnomon, supported by EST evidence. Also see: Documentation of NCBI's Annotation Process On Aug 8, 2019 this sequence version replaced XM_006509226.3. ##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Name :: Mus musculus Annotation Release 108 Annotation Version :: 108 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 8.2 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END## |
1 | ATGATAACAT CTGAGGATCG GGTCCAAGAA GGGAAAAAAG TTGTGAAACT CAAAACAGAA |
The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.
RefSeq | XP_006509289.1 |
CDS | 412..2205 |
Translation |
Target ORF information:
Target ORF information:
|
![]() |
1 | ATGATAACAT CTGAGGATCG GGTCCAAGAA GGGAAAAAAG TTGTGAAACT CAAAACAGAA |
The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.
CKAP2 phosphorylation by CDK1/cyclinB1 is crucial for maintaining centrosome integrity. |
Lamin-B1 contributes to the proper timing of epicardial cell migration and function during embryonic heart development. |
CKAP2 is necessary to ensure the faithful spindle bipolarity in a dividing diploid hepatocyte. |
The Interleukin-2-mTORc1 Kinase Axis Defines the Signaling, Differentiation, and Metabolism of T Helper 1 and Follicular B Helper T Cells. |
Angiogenesis QTL on Mouse Chromosome 8 Colocalizes with Differential ?-Defensin Expression. |