Gene Symbol | Jdp2 |
Entrez Gene ID | 81703 |
Full Name | Jun dimerization protein 2 |
Synonyms | Jundm2,Jundp2,TIF |
General protein information |
|
Gene Type | protein-coding |
Organism | Mus musculus(house mouse) |
Genome |
ORF » Species Summary » Mus musculus » Jdp2 cDNA ORF clone
Gene Symbol | Jdp2 |
Entrez Gene ID | 81703 |
Full Name | Jun dimerization protein 2 |
Synonyms | Jundm2,Jundp2,TIF |
General protein information |
|
Gene Type | protein-coding |
Organism | Mus musculus(house mouse) |
Genome |
mRNA | Protein | Name |
---|---|---|
NM_030887.2 | NP_112149.2 | jun dimerization protein 2 |
XM_011244218.1 | XP_011242520.1 | jun dimerization protein 2 isoform X1 |
XM_011244219.2 | XP_011242521.1 | jun dimerization protein 2 isoform X2 |
XM_011244218.2 | XP_011242520.1 | jun dimerization protein 2 isoform X1 |
XM_011244219.3 | XP_011242521.1 | jun dimerization protein 2 isoform X2 |
NM_001205053.1 | NP_001191982.1 | jun dimerization protein 2 |
NM_001205052.1 | NP_001191981.1 | jun dimerization protein 2 |
Homo sapiens (human) | JDP2 | NP_001128521.1 |
Pan troglodytes (chimpanzee) | JDP2 | XP_001160035.2 |
Bos taurus (cattle) | JDP2 | NP_001180174.1 |
Canis lupus familiaris (dog) | JDP2 | XP_005623731.1 |
Rattus norvegicus (Norway rat) | Jdp2 | NP_446346.1 |
Gallus gallus (chicken) | JDP2 | NP_001264816.1 |
Danio rerio (zebrafish) | LOC570258 | XP_005158992.1 |
Mus musculus (house mouse) | Jdp2 | NP_112149.2 |
Nociceptors Boost the Resolution of Fungal Osteoinflammation via the TRP Channel-CGRP-Jdp2 Axis.
Maruyama K, Takayama Y, Kondo T, Ishibashi KI, Sahoo BR, Kanemaru H, Kumagai Y, Martino MM, Tanaka H, Ohno N, Iwakura Y, Takemura N, Tominaga M, Akira S
Cell reports19(13)2730-2742(2017 Jun)
GeneRIFs: Gene References Into Functions What's a GeneRIF?
Female JDP2 null mice, however, exhibited early puberty, observed as early vaginal opening, larger litters, and early reproductive senescence. JDP2 null females had increased levels of circulating FSH and higher expression of the Fshb subunit in the pituitary, resulting in elevated serum estrogen and higher numbers of large ovarian follicles
Title: c-JUN Dimerization Protein 2 (JDP2) Is a Transcriptional Repressor of Follicle-stimulating Hormone ? (FSH?) and Is Required for Preventing Premature Reproductive Senescence in Female Mice.
JDP2 acts as a novel transcriptional activator of the mouse Mc2r gene, suggesting that JDP2 may have physiological functions as a novel player in MC2R-mediated steroidogenesis as well as cell signaling in adrenal glands.
Title: Jun Dimerization Protein 2 Activates Mc2r Transcriptional Activity: Role of Phosphorylation and SUMOylation.
High JDP2 expression in the bone marrow contributes to metastatic spread in the lung.
Title: Host JDP2 expression in the bone marrow contributes to metastatic spread.
results suggest a negative feedback loop between JDP2 and p53, and a direct link between JDP2 and a key oncogenic pathway
Title: Cloning and characterization of the mouse JDP2 gene promoter reveal negative regulation by p53.
Tbx3 plays an important role in osteoclastogenesis at least in part by regulating CSF1-dependent expression of JDP2.
Title: The transcription factor T-box 3 regulates colony-stimulating factor 1-dependent Jun dimerization protein 2 expression and plays an important role in osteoclastogenesis.
The following Jdp2 gene cDNA ORF clone sequences were retrieved from the NCBI Reference Sequence Database (RefSeq). These sequences represent the protein coding region of the Jdp2 cDNA ORF which is encoded by the open reading frame (ORF) sequence. ORF sequences can be delivered in our standard vector, pcDNA3.1+/C-(K)DYK or the vector of your choice as an expression/transfection-ready ORF clone. Not the clone you want? Click here to find your clone.
CloneID | OMu17942 | |
Clone ID Related Accession (Same CDS sequence) | NM_030887.2 , NM_001205053.1 , NM_001205052.1 | |
Accession Version | NM_030887.2 Latest version! | Documents for ORF clone product in default vector |
Sequence Information | ORF Nucleotide Sequence (Length: 492bp) Protein sequence SNP |
|
Vector | pcDNA3.1-C-(k)DYK or customized vector | User Manual |
Clone information | Clone Map | MSDS |
Tag on pcDNA3.1+/C-(K)DYK | C terminal DYKDDDDK tags | |
ORF Insert Method | CloneEZ™ Seamless cloning technology | |
Insert Structure | linear | |
Update Date | 2019-12-25 | |
Organism | Mus musculus(house mouse) | |
Product | jun dimerization protein 2 | |
Comment | Comment: VALIDATED REFSEQ: This record has undergone validation or preliminary review. The reference sequence was derived from AB077438.1. On Jun 19, 2003 this sequence version replaced NM_030887.1. Transcript Variant: This variant (1) represents the longest transcript. Variants 1, 2 and 3 encode the same protein. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Gene record to access additional publications. ##Evidence-Data-START## Transcript exon combination :: AB077438.1, AA667990.1 [ECO:0000332] RNAseq introns :: single sample supports all introns SAMN00849374, SAMN00849375 [ECO:0000348] ##Evidence-Data-END## COMPLETENESS: complete on the 3' end. |
1 | ATGATGCCTG GGCAGATCCC AGACCCTTCA GTGACCGCAG GCTCTCTGCC AGGGCTCGGC |
The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.
RefSeq | NP_112149.2 |
CDS | 232..723 |
Translation |
Target ORF information:
Target ORF information:
|
NM_030887.2 |
1 | ATGATGCCTG GGCAGATCCC AGACCCTTCA GTGACCGCAG GCTCTCTGCC AGGGCTCGGC |
The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.
CloneID | OMu17942 | |
Clone ID Related Accession (Same CDS sequence) | NM_030887.2 , NM_001205053.1 , NM_001205052.1 | |
Accession Version | NM_001205053.1 Latest version! | Documents for ORF clone product in default vector |
Sequence Information | ORF Nucleotide Sequence (Length: 492bp) Protein sequence SNP |
|
Vector | pcDNA3.1-C-(k)DYK or customized vector | User Manual |
Clone information | Clone Map | MSDS |
Tag on pcDNA3.1+/C-(K)DYK | C terminal DYKDDDDK tags | |
ORF Insert Method | CloneEZ™ Seamless cloning technology | |
Insert Structure | linear | |
Update Date | 2019-12-26 | |
Organism | Mus musculus(house mouse) | |
Product | jun dimerization protein 2 | |
Comment | Comment: VALIDATED REFSEQ: This record has undergone validation or preliminary review. The reference sequence was derived from AC115037.16. Transcript Variant: This variant (3) differs in the 5' UTR, compared to variant 1. Variants 1, 2 and 3 encode the same protein. Sequence Note: The RefSeq transcript and protein were derived from genomic sequence to make the sequence consistent with the reference genome assembly. The genomic coordinates used for the transcript record were based on alignments. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Gene record to access additional publications. ##Evidence-Data-START## Transcript exon combination :: AB034697.1 [ECO:0000332] RNAseq introns :: single sample supports all introns SAMN01164131, SAMN01164132 [ECO:0000348] ##Evidence-Data-END## COMPLETENESS: complete on the 3' end. |
1 | ATGATGCCTG GGCAGATCCC AGACCCTTCA GTGACCGCAG GCTCTCTGCC AGGGCTCGGC |
The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.
RefSeq | NP_001191982.1 |
CDS | 148..639 |
Translation |
Target ORF information:
Target ORF information:
|
NM_001205053.1 |
1 | ATGATGCCTG GGCAGATCCC AGACCCTTCA GTGACCGCAG GCTCTCTGCC AGGGCTCGGC |
The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.
CloneID | OMu17942 | |
Clone ID Related Accession (Same CDS sequence) | NM_030887.2 , NM_001205053.1 , NM_001205052.1 | |
Accession Version | NM_001205052.1 Latest version! | Documents for ORF clone product in default vector |
Sequence Information | ORF Nucleotide Sequence (Length: 492bp) Protein sequence SNP |
|
Vector | pcDNA3.1-C-(k)DYK or customized vector | User Manual |
Clone information | Clone Map | MSDS |
Tag on pcDNA3.1+/C-(K)DYK | C terminal DYKDDDDK tags | |
ORF Insert Method | CloneEZ™ Seamless cloning technology | |
Insert Structure | linear | |
Update Date | 2019-12-26 | |
Organism | Mus musculus(house mouse) | |
Product | jun dimerization protein 2 | |
Comment | Comment: VALIDATED REFSEQ: This record has undergone validation or preliminary review. The reference sequence was derived from AC115037.16. Transcript Variant: This variant (2) differs in the 5' UTR, compared to variant 1. Variants 1, 2 and 3 encode the same protein. Sequence Note: The RefSeq transcript and protein were derived from genomic sequence to make the sequence consistent with the reference genome assembly. The genomic coordinates used for the transcript record were based on alignments. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Gene record to access additional publications. ##Evidence-Data-START## Transcript exon combination :: BC019780.1, BF134255.1 [ECO:0000332] RNAseq introns :: single sample supports all introns SAMN00849374, SAMN00849375 [ECO:0000348] ##Evidence-Data-END## COMPLETENESS: complete on the 3' end. |
1 | ATGATGCCTG GGCAGATCCC AGACCCTTCA GTGACCGCAG GCTCTCTGCC AGGGCTCGGC |
The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.
RefSeq | NP_001191981.1 |
CDS | 156..647 |
Translation |
Target ORF information:
Target ORF information:
|
NM_001205052.1 |
1 | ATGATGCCTG GGCAGATCCC AGACCCTTCA GTGACCGCAG GCTCTCTGCC AGGGCTCGGC |
The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.
CloneID | OMu71847 | |
Clone ID Related Accession (Same CDS sequence) | XM_011244218.1 , XM_011244218.2 | |
Accession Version | XM_011244218.2 Latest version! | Documents for ORF clone product in default vector |
Sequence Information | ORF Nucleotide Sequence (Length: 861bp) Protein sequence SNP |
|
Vector | pcDNA3.1-C-(k)DYK or customized vector | User Manual |
Clone information | Clone Map | MSDS |
Tag on pcDNA3.1+/C-(K)DYK | C terminal DYKDDDDK tags | |
ORF Insert Method | CloneEZ™ Seamless cloning technology | |
Insert Structure | linear | |
Update Date | 2019-08-07 | |
Organism | Mus musculus(house mouse) | |
Product | jun dimerization protein 2 isoform X1 | |
Comment | Comment: MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_000078.6) annotated using gene prediction method: Gnomon, supported by mRNA and EST evidence. Also see: Documentation of NCBI's Annotation Process On Aug 8, 2019 this sequence version replaced XM_011244218.1. ##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Name :: Mus musculus Annotation Release 108 Annotation Version :: 108 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 8.2 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END## |
1 | ATGGTTCGGC GTGGGCTGAG CTGGAAGGGG TTCTCTGCTC ATCCGGCCGC CGCCTTCGCG |
The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.
RefSeq | XP_011242520.1 |
CDS | 275..1135 |
Translation |
Target ORF information:
Target ORF information:
|
XM_011244218.2 |
1 | ATGGTTCGGC GTGGGCTGAG CTGGAAGGGG TTCTCTGCTC ATCCGGCCGC CGCCTTCGCG |
The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.
CloneID | OMu71848 | |
Clone ID Related Accession (Same CDS sequence) | XM_011244219.2 , XM_011244219.3 | |
Accession Version | XM_011244219.3 Latest version! | Documents for ORF clone product in default vector |
Sequence Information | ORF Nucleotide Sequence (Length: 822bp) Protein sequence SNP |
|
Vector | pcDNA3.1-C-(k)DYK or customized vector | User Manual |
Clone information | Clone Map | MSDS |
Tag on pcDNA3.1+/C-(K)DYK | C terminal DYKDDDDK tags | |
ORF Insert Method | CloneEZ™ Seamless cloning technology | |
Insert Structure | linear | |
Update Date | 2019-08-07 | |
Organism | Mus musculus(house mouse) | |
Product | jun dimerization protein 2 isoform X2 | |
Comment | Comment: MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_000078.6) annotated using gene prediction method: Gnomon, supported by mRNA and EST evidence. Also see: Documentation of NCBI's Annotation Process On Aug 8, 2019 this sequence version replaced XM_011244219.2. ##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Name :: Mus musculus Annotation Release 108 Annotation Version :: 108 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 8.2 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END## |
1 | ATGGTTCGGC GTGGGCTGAG CTGGAAGGGG TTCTCTGCTC ATCCGGCCGC CGCCTTCGCG |
The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.
RefSeq | XP_011242521.1 |
CDS | 275..1096 |
Translation |
Target ORF information:
Target ORF information:
|
XM_011244219.3 |
1 | ATGGTTCGGC GTGGGCTGAG CTGGAAGGGG TTCTCTGCTC ATCCGGCCGC CGCCTTCGCG |
The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.
CloneID | OMu71847 | |
Clone ID Related Accession (Same CDS sequence) | XM_011244218.1 , XM_011244218.2 | |
Accession Version | XM_011244218.1 | Documents for ORF clone product in default vector |
Sequence Information | ORF Nucleotide Sequence (Length: 861bp) Protein sequence SNP |
|
Vector | pcDNA3.1-C-(k)DYK or customized vector | User Manual |
Clone information | Clone Map | MSDS |
Tag on pcDNA3.1+/C-(K)DYK | C terminal DYKDDDDK tags | |
ORF Insert Method | CloneEZ™ Seamless cloning technology | |
Insert Structure | linear | |
Update Date | 2016-06-21 | |
Organism | Mus musculus(house mouse) | |
Product | jun dimerization protein 2 isoform X1 | |
Comment | Comment: MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_000078.6) annotated using gene prediction method: Gnomon, supported by mRNA and EST evidence. Also see: Documentation of NCBI's Annotation Process ##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Version :: Mus musculus Annotation Release 106 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 7.1 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END## |
1 | ATGGTTCGGC GTGGGCTGAG CTGGAAGGGG TTCTCTGCTC ATCCGGCCGC CGCCTTCGCG |
The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.
RefSeq | XP_011242520.1 |
CDS | 317..1177 |
Translation |
Target ORF information:
Target ORF information:
|
XM_011244218.1 |
1 | ATGGTTCGGC GTGGGCTGAG CTGGAAGGGG TTCTCTGCTC ATCCGGCCGC CGCCTTCGCG |
The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.
CloneID | OMu71848 | |
Clone ID Related Accession (Same CDS sequence) | XM_011244219.2 , XM_011244219.3 | |
Accession Version | XM_011244219.2 | Documents for ORF clone product in default vector |
Sequence Information | ORF Nucleotide Sequence (Length: 822bp) Protein sequence SNP |
|
Vector | pcDNA3.1-C-(k)DYK or customized vector | User Manual |
Clone information | Clone Map | MSDS |
Tag on pcDNA3.1+/C-(K)DYK | C terminal DYKDDDDK tags | |
ORF Insert Method | CloneEZ™ Seamless cloning technology | |
Insert Structure | linear | |
Update Date | 2016-06-21 | |
Organism | Mus musculus(house mouse) | |
Product | jun dimerization protein 2 isoform X2 | |
Comment | Comment: MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_000078.6) annotated using gene prediction method: Gnomon, supported by mRNA and EST evidence. Also see: Documentation of NCBI's Annotation Process On Jun 22, 2016 this sequence version replaced XM_011244219.1. ##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Version :: Mus musculus Annotation Release 106 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 7.1 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END## |
1 | ATGGTTCGGC GTGGGCTGAG CTGGAAGGGG TTCTCTGCTC ATCCGGCCGC CGCCTTCGCG |
The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.
RefSeq | XP_011242521.1 |
CDS | 314..1135 |
Translation |
Target ORF information:
Target ORF information:
|
XM_011244219.2 |
1 | ATGGTTCGGC GTGGGCTGAG CTGGAAGGGG TTCTCTGCTC ATCCGGCCGC CGCCTTCGCG |
The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.
Nociceptors Boost the Resolution of Fungal Osteoinflammation via the TRP Channel-CGRP-Jdp2 Axis. |