Gene Symbol | Jam3 |
Entrez Gene ID | 83964 |
Full Name | junction adhesion molecule 3 |
Synonyms | 1110002N23Rik,JAM-3,JAM-C,Jcam3 |
General protein information |
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Gene Type | protein-coding |
Organism | Mus musculus(house mouse) |
Genome |
ORF » Species Summary » Mus musculus » Jam3 cDNA ORF clone
gRNAs
Gene Symbol | Jam3 |
Entrez Gene ID | 83964 |
Full Name | junction adhesion molecule 3 |
Synonyms | 1110002N23Rik,JAM-3,JAM-C,Jcam3 |
General protein information |
|
Gene Type | protein-coding |
Organism | Mus musculus(house mouse) |
Genome |
mRNA | Protein | Name |
---|---|---|
XM_030244741.1 | XP_030100601.1 | junctional adhesion molecule C isoform X1 |
NM_023277.4 | NP_075766.1 | junctional adhesion molecule C precursor |
Canis lupus familiaris (dog) | JAM3 | XP_005619600.1 |
Xenopus tropicalis (tropical clawed frog) | jam3 | XP_004916068.1 |
Homo sapiens (human) | JAM3 | NP_116190.3 |
Bos taurus (cattle) | JAM3 | NP_001098834.1 |
Mus musculus (house mouse) | Jam3 | NP_075766.1 |
Danio rerio (zebrafish) | jam3a | XP_001338123.1 |
Pan troglodytes (chimpanzee) | JAM3 | XP_529458.3 |
Rattus norvegicus (Norway rat) | Jam3 | NP_001004269.1 |
Gallus gallus (chicken) | JAM3 | XP_004948061.1 |
Danio rerio (zebrafish) | jam3b | NP_001076332.2 |
JAM-C maintains VEGR2 expression to promote retinal pigment epithelium cell survival under oxidative stress.
Jia X, Zhao C, Chen Q, Du Y, Huang L, Ye Z, Ren X, Wang S, Lee C, Tang Z, Li X, Ju R
Thrombosis and haemostasis117(4)750-757(2017 Apr)
GeneRIFs: Gene References Into Functions What's a GeneRIF?
JAM-B/JAM-C mediated interaction between endothelial cells and stellate cells stabilizes vessel walls and may control the sinusoidal diameter.
Title: Murine junctional adhesion molecules JAM-B and JAM-C mediate endothelial and stellate cell interactions during hepatic fibrosis.
Study provides evidence that JAM-C downregulation may contribute to acute pancreatitis-associated lung injury via reverse transendothelial migration of neutrophils.
Title: Reverse-migrated neutrophils regulated by JAM-C are involved in acute pancreatitis-associated lung injury.
Endothelial-specific deletion of JAM-C promoted endothelial cell sprouting, and consequently vessel normalisation and revascularisation of the hypoxic retina without altering pathologic neovascularisation.
Title: Endothelial-specific deficiency of Junctional Adhesion Molecule-C promotes vessel normalisation in proliferative retinopathy.
JAM-C blockade can finely-tune the innate cell migration and accelerate the consequent immune response to L. major without changing the type of the T helper cell response.
Title: Blocking junctional adhesion molecule C enhances dendritic cell migration and boosts the immune responses against Leishmania major.
Function of Jam-B/Jam-C interaction in homing and mobilization of human and mouse hematopoietic stem and progenitor cells.
Title: Function of Jam-B/Jam-C interaction in homing and mobilization of human and mouse hematopoietic stem and progenitor cells.
The following Jam3 gene cDNA ORF clone sequences were retrieved from the NCBI Reference Sequence Database (RefSeq). These sequences represent the protein coding region of the Jam3 cDNA ORF which is encoded by the open reading frame (ORF) sequence. ORF sequences can be delivered in our standard vector, pcDNA3.1+/C-(K)DYK or the vector of your choice as an expression/transfection-ready ORF clone. Not the clone you want? Click here to find your clone.
CloneID | OMu01144 | |
Clone ID Related Accession (Same CDS sequence) | NM_023277.4 | |
Accession Version | NM_023277.4 Latest version! | Documents for ORF clone product in default vector |
Sequence Information | ORF Nucleotide Sequence (Length: 933bp) Protein sequence SNP |
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Vector | pcDNA3.1-C-(k)DYK or customized vector | ![]() |
Clone information | Clone Map | ![]() |
Tag on pcDNA3.1+/C-(K)DYK | C terminal DYKDDDDK tags | |
ORF Insert Method | CloneEZ™ Seamless cloning technology | |
Insert Structure | linear | |
Update Date | 2019-12-27 | |
Organism | Mus musculus(house mouse) | |
Product | junctional adhesion molecule C precursor | |
Comment | Comment: VALIDATED REFSEQ: This record has undergone validation or preliminary review. The reference sequence was derived from AW106511.1, AK013156.1 and AI850297.1. On Mar 22, 2011 this sequence version replaced NM_023277.3. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Gene record to access additional publications. ##Evidence-Data-START## Transcript exon combination :: BC024357.1, AK003326.1 [ECO:0000332] RNAseq introns :: single sample supports all introns SAMN00849382, SAMN00849385 [ECO:0000348] ##Evidence-Data-END## COMPLETENESS: complete on the 3' end. |
1 | ATGGCGCTGA GCCGGCGGCT GCGACTTCGA CTGTACGCGC GGCTGCCTGA CTTCTTCCTG |
The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.
RefSeq | NP_075766.1 |
CDS | 56..988 |
Translation |
Target ORF information:
Target ORF information:
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1 | ATGGCGCTGA GCCGGCGGCT GCGACTTCGA CTGTACGCGC GGCTGCCTGA CTTCTTCCTG |
The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.
CloneID | OMu90325 | |
Clone ID Related Accession (Same CDS sequence) | XM_030244741.1 | |
Accession Version | XM_030244741.1 Latest version! | Documents for ORF clone product in default vector |
Sequence Information | ORF Nucleotide Sequence (Length: 852bp) Protein sequence SNP |
|
Vector | pcDNA3.1-C-(k)DYK or customized vector | ![]() |
Clone information | Clone Map | ![]() |
Tag on pcDNA3.1+/C-(K)DYK | C terminal DYKDDDDK tags | |
ORF Insert Method | CloneEZ™ Seamless cloning technology | |
Insert Structure | linear | |
Update Date | 2019-08-07 | |
Organism | Mus musculus(house mouse) | |
Product | junctional adhesion molecule C isoform X1 | |
Comment | Comment: MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_000075.6) annotated using gene prediction method: Gnomon, supported by EST evidence. Also see: Documentation of NCBI's Annotation Process ##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Name :: Mus musculus Annotation Release 108 Annotation Version :: 108 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 8.2 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END## |
1 | ATGATAGAGG CAGTGAATCT CAAATCCAGC AACCGAAACC CAGTGGTACA TGAATTTGAA |
The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.
RefSeq | XP_030100601.1 |
CDS | 3755..4606 |
Translation |
Target ORF information:
Target ORF information:
|
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1 | ATGATAGAGG CAGTGAATCT CAAATCCAGC AACCGAAACC CAGTGGTACA TGAATTTGAA |
The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.
JAM-C maintains VEGR2 expression to promote retinal pigment epithelium cell survival under oxidative stress. |