H3c8 cDNA ORF clone, Mus musculus(house mouse)
| Gene Symbol | H3c8 |
| Entrez Gene ID | 97908 |
| Full Name | histone cluster 1, H3g |
| Synonyms | H3.1-221,M32460 |
| General protein information |
|
| Gene Type | protein-coding |
| Organism | Mus musculus(house mouse) |
| Genome | |
| Summary | Histones are basic nuclear proteins that are responsible for the nucleosome structure of the chromosomal fiber in eukaryotes. Two molecules of each of the four core histones (H2A, H2B, H3, and H4) form an octamer, around which approximately 146 bp of DNA is wrapped in repeating units, called nucleosomes. The linker histone, H1, interacts with linker DNA between nucleosomes and functions in the compaction of chromatin into higher order structures. This gene is intronless and encodes a replication-dependent histone that is a member of the histone H3 family. Transcripts from this gene lack polyA tails but instead contain a palindromic termination element. [provided by RefSeq, Aug 2015]. |
mRNA and Protein(s)
| mRNA | Protein | Name |
|---|---|---|
| NM_145073.2 | NP_659539.1 | histone H3.1 |
| LOC100425854 | XP_002803686.1 | |
| Bos taurus (cattle) | LOC540148 | XP_002697552.2 |
| Caenorhabditis elegans (roundworm) | his-25 | NP_496895.1 |
| Arabidopsis thaliana (thale cress) | AT4G40030 | NP_001078516.1 |
| Oryza sativa (rice) | Os06g0130900 | NP_001056693.1 |
| Mus musculus (house mouse) | Hist1h3g | NP_659539.1 |
| Caenorhabditis elegans (roundworm) | his-17 | NP_505297.1 |
| Caenorhabditis elegans (roundworm) | his-42 | NP_496899.1 |
| Caenorhabditis elegans (roundworm) | his-63 | NP_502153.1 |
| Homo sapiens (human) | HIST1H3J | NP_003526.1 |
| Canis lupus familiaris (dog) | LOC488277 | XP_005640184.1 |
| Danio rerio (zebrafish) | LOC100004914 | XP_005172223.1 |
| Caenorhabditis elegans (roundworm) | his-6 | NP_505199.1 |
| Caenorhabditis elegans (roundworm) | his-49 | NP_505276.1 |
| Caenorhabditis elegans (roundworm) | his-2 | NP_507033.1 |
| Caenorhabditis elegans (roundworm) | his-13 | NP_496890.1 |
| Caenorhabditis elegans (roundworm) | his-45 | NP_502134.1 |
| Xenopus tropicalis (tropical clawed frog) | LOC101732029 | XP_004915774.1 |
| Pan troglodytes (chimpanzee) | LOC471875 | XP_527253.2 |
| Rattus norvegicus (Norway rat) | LOC680498 | XP_001057443.3 |
| Drosophila melanogaster (fruit fly) | His3:CG33830 | NP_001027328.1 |
| Caenorhabditis elegans (roundworm) | his-55 | NP_502138.1 |
| Caenorhabditis elegans (roundworm) | his-9 | NP_496894.1 |
| Caenorhabditis elegans (roundworm) | his-32 | NP_501407.1 |
| Caenorhabditis elegans (roundworm) | his-27 | NP_505292.1 |
| Caenorhabditis elegans (roundworm) | his-59 | NP_501204.1 |
| Arabidopsis thaliana (thale cress) | AT5G10980 | NP_196659.1 |
| Arabidopsis thaliana (thale cress) | AT4G40040 | NP_849529.1 |
Related articles in PubMed
cAMP response element binding protein is required for differentiation of respiratory epithelium during murine development.
Bird AD, Flecknoe SJ, Tan KH, Olsson PF, Antony N, Mantamadiotis T, Mollard R, Hooper SB, Cole TJ
PloS one6(3)e17843(2011 Mar)
Organismal differences in post-translational modifications in histones H3 and H4.
Garcia BA, Hake SB, Diaz RL, Kauer M, Morris SA, Recht J, Shabanowitz J, Mishra N, Strahl BD, Allis CD, Hunt DF
The Journal of biological chemistry282(10)7641-55(2007 Mar)
Identification of histone H3 lysine 36 acetylation as a highly conserved histone modification.
Morris SA, Rao B, Garcia BA, Hake SB, Diaz RL, Shabanowitz J, Hunt DF, Allis CD, Lieb JD, Strahl BD
The Journal of biological chemistry282(10)7632-40(2007 Mar)
Stimulation of the Ras-MAPK pathway leads to independent phosphorylation of histone H3 on serine 10 and 28.
Dunn KL, Davie JR
Oncogene24(21)3492-502(2005 May)
MAP kinase-mediated phosphorylation of distinct pools of histone H3 at S10 or S28 via mitogen- and stress-activated kinase 1/2.
Dyson MH, Thomson S, Inagaki M, Goto H, Arthur SJ, Nightingale K, Iborra FJ, Mahadevan LC
Journal of cell science118(Pt 10)2247-59(2005 May)
GeneRIFs: Gene References Into Functions What's a GeneRIF?
The following H3c8 gene cDNA ORF clone sequences were retrieved from the NCBI Reference Sequence Database (RefSeq). These sequences represent the protein coding region of the H3c8 cDNA ORF which is encoded by the open reading frame (ORF) sequence. ORF sequences can be delivered in our standard vector, pcDNA3.1+/C-(K)DYK or the vector of your choice as an expression/transfection-ready ORF clone. Not the clone you want? Click here to find your clone.
| CloneID | OMu14644 | |
| Clone ID Related Accession (Same CDS sequence) | NM_145073.2 | |
| Accession Version | NM_145073.2 Latest version! | Documents for ORF clone product in default vector |
| Sequence Information | ORF Nucleotide Sequence (Length: 411bp) Protein sequence SNP |
|
| Vector | pcDNA3.1-C-(k)DYK or customized vector |  User Manual |
| Clone information | Clone Map | MSDS |
| Tag on pcDNA3.1+/C-(K)DYK | C terminal DYKDDDDK tags | |
| ORF Insert Method | CloneEZ™ Seamless cloning technology | |
| Insert Structure | linear | |
| Update Date | 2019-11-14 | |
| Organism | Mus musculus(house mouse) | |
| Product | histone H3.1 | |
| Comment | Comment: REVIEWED REFSEQ: This record has been curated by NCBI staff. The reference sequence was derived from AL592149.8. On Sep 21, 2005 this sequence version replaced NM_145073.1. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Gene record to access additional publications. ##Evidence-Data-START## Transcript is intronless :: BC125355.1 [ECO:0000345] ##Evidence-Data-END## ##RefSeq-Attributes-START## replication-dependent histone :: PMID: 12408966 ##RefSeq-Attributes-END## COMPLETENESS: complete on the 3' end. | |
1 | ATGGCTCGTA CTAAGCAGAC CGCTCGCAAG TCTACCGGCG GCAAGGCCCC GCGCAAGCAG |
The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.
| RefSeq | NP_659539.1 |
| CDS | 29..439 |
| Translation |
Target ORF information:
Target ORF information:
|
 NM_145073.2 |
ORF Insert Sequence:
1 | ATGGCTCGTA CTAAGCAGAC CGCTCGCAAG TCTACCGGCG GCAAGGCCCC GCGCAAGCAG |
The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.
 |
cAMP response element binding protein is required for differentiation of respiratory epithelium during murine development. |
|
Organismal differences in post-translational modifications in histones H3 and H4. |
|
Identification of histone H3 lysine 36 acetylation as a highly conserved histone modification. |
|
Stimulation of the Ras-MAPK pathway leads to independent phosphorylation of histone H3 on serine 10 and 28. |
|
MAP kinase-mediated phosphorylation of distinct pools of histone H3 at S10 or S28 via mitogen- and stress-activated kinase 1/2. |