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Bmp6 cDNA ORF clone, Mus musculus(house mouse)

Summary

Gene Symbol Bmp6
Entrez Gene ID 12161
Full Name bone morphogenetic protein 6
Synonyms D13Wsu115e,Vgr1
General protein information
Preferred Names

bone morphogenetic protein 6

Names

bone morphogenetic protein 6
VG-1-related protein
Gene Type protein-coding
Organism Mus musculus(house mouse)
Genome

13

13 A3.3|13 18.15 cM
Summary This gene encodes a secreted ligand of the TGF-beta (transforming growth factor-beta) superfamily of proteins. Ligands of this family bind various TGF-beta receptors leading to recruitment and activation of SMAD family transcription factors that regulate gene expression. The encoded preproprotein is proteolytically processed to generate each subunit of the disulfide-linked homodimer. This protein regulates a wide range of biological processes including iron homeostasis, fat and bone development, and ovulation. Mice lacking this gene exhibit delayed ossification of the sternum, iron overload, and reduced fertility in females. [provided by RefSeq, Jul 2016].

Reference Sequences (RefSeq)

mRNA and Protein(s)

mRNA Protein Name
NM_007556.2 NP_031582.1 bone morphogenetic protein 6 precursor
NM_007556.3 NP_031582.1 bone morphogenetic protein 6 preproprotein

Pathways from BioSystems


Homologies


BMP6 XP_001085364.1
Mus musculus (house mouse) Bmp6 NP_031582.1
Homo sapiens (human) BMP6 NP_001709.1
Pan troglodytes (chimpanzee) BMP6 XP_003950760.1
Rattus norvegicus (Norway rat) Bmp6 NP_037239.1
Bos taurus (cattle) BMP6 XP_005223949.1
Gallus gallus (chicken) BMP6 XP_418956.4
Danio rerio (zebrafish) bmp6 NP_001013357.1
Xenopus tropicalis (tropical clawed frog) bmp6 NP_001106378.1

Gene Ontology

The following Bmp6 gene cDNA ORF clone sequences were retrieved from the NCBI Reference Sequence Database (RefSeq). These sequences represent the protein coding region of the Bmp6 cDNA ORF which is encoded by the open reading frame (ORF) sequence. ORF sequences can be delivered in our standard vector, pcDNA3.1+/C-(K)DYK or the vector of your choice as an expression/transfection-ready ORF clone. Not the clone you want? Click here to find your clone.

***CloneID Accession No. Definition **Vector *Turnaround time Price (USD) Select
OMu14173 NM_007556.3
Latest version!		 Mus musculus bone morphogenetic protein 6 (Bmp6), mRNA. pcDNA3.1+/C-(K)DYK or customized vector TBD $300.30
$429.00
View Old Accession Versions >>
OMu14173 NM_007556.2 Mus musculus bone morphogenetic protein 6 (Bmp6), mRNA. pcDNA3.1+/C-(K)DYK or customized vector TBD $300.30
$429.00
Hide Old Accession Versions >>

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** You may select a custom vector to replace pcDNA3.1+/C-(K)DYK after clone is added to cart.

** GenScript guarantees 100% sequence accuracy of all synthetic DNA constructs we deliver, but we do not guarantee protein expression in your experimental system. Protein expression is influenced by many factors that may vary between experiments or laboratories. In addition, please pay attention to the signal peptide, propeptide and transit peptide in target ORF, which may affect the choice of vector (N/C terminal tag vector).

***One clone ID might be correlated to multiple accession numbers, which share the same CDS sequence.

Reference Sequences (Refseq)


CloneID OMu14173
Clone ID Related Accession (Same CDS sequence) NM_007556.2 , NM_007556.3
Accession Version NM_007556.2 Documents for ORF clone product in default vector
Sequence Information ORF Nucleotide Sequence (Length: 1533bp)
Protein sequence
SNP
Vector pcDNA3.1+/C-(K)DYK or customized vector User Manual
Clone information Clone Map MSDS
Tag on pcDNA3.1+/C-(K)DYK C terminal DYKDDDDK tags
ORF Insert Method CloneEZ™ Seamless cloning technology
Insert Structure linear
Update Date 2015-02-14
Organism Mus musculus(House mouse)
Product bone morphogenetic protein 6 precursor
Comment 

1
61
121
181
241
301
361
421
481
541
601
661
721
781
841
901
961
1021
1081
1141
1201
1261
1321
1381
1441
1501
ATGCCCGGGC TGGGGCGGAG GGCGCAGTGG CTGTGCTGGT GGTGGGGGTT GCTGTGCAGC 
TGCGGCCCCC CGCCACTGCG GCCCCCTCTG CCGGTAGCCG CGGCCGCCGC CGGGGGGCAG 
CTGCTGGGAG CCGGCGGGAG CCCGGTGCGC GCTGAGCAGC CACCGCCACA GTCCTCTTCT 
TCGGGCTTCC TCTATCGGCG GCTCAAGACC CACGAGAAGC GGGAGATGCA AAAGGAGATC 
CTGTCGGTGC TGGGGCTCCC GCACAGGCCG CGGCCCCTGC ACGGTCTCCA GCAGCCTCAG 
CCCCCGGTGC TCCCGCCACA GCAGCAGCAG CAGCAGCAGC AGCAGCAGAC GGCCCGCGAG 
GAGCCCCCTC CAGGGCGGCT GAAGTCCGCT CCACTCTTCA TGCTGGATCT CTACAACGCC 
CTGTCCAATG ACGACGAAGA GGATGGGGCA TCGGAGGGTG TGGGGCAAGA GCCTGGGTCC 
CACGGAGGGG CCAGCTCGTC CCAGCTCAGG CAGCCGTCTC CCGGCGCTGC ACACTCCTTG 
AACCGCAAGA GTCTCCTGGC CCCGGGACCC GGTGGCGGTG CGTCCCCACT GACTAGCGCG 
CAGGACAGCG CTTTCCTCAA CGACGCGGAC ATGGTCATGA GCTTTGTGAA CCTGGTGGAG 
TACGACAAGG AGTTCTCCCC ACATCAACGA CACCACAAAG AGTTCAAGTT CAACCTATCC 
CAGATTCCTG AGGGTGAGGC GGTGACGGCT GCTGAGTTCC GCGTCTACAA GGACTGTGTG 
GTGGGGAGTT TTAAAAACCA AACCTTTCTT ATCAGCATTT ACCAAGTCTT GCAGGAGCAT 
CAGCACAGAG ACTCTGACCT ATTTTTGTTG GACACCCGGG TGGTGTGGGC CTCAGAAGAA 
GGTTGGCTGG AATTTGACAT CACAGCAACT AGCAATCTGT GGGTGGTGAC ACCGCAGCAC 
AACATGGGGC TCCAGCTGAG TGTGGTGACT CGGGATGGAC TCCACGTCAA CCCCCGTGCG 
GCGGGCCTGG TGGGCAGAGA CGGCCCTTAC GACAAGCAGC CCTTCATGGT GGCCTTCTTC 
AAGGTGAGCG AGGTCCACGT GCGCACCACC AGGTCAGCCT CCAGTCGGCG GCGGCAGCAG 
AGTCGCAACC GGTCCACCCA GTCGCAGGAC GTGTCCCGGG GCTCCGGTTC TTCAGACTAC 
AACGGCAGTG AGTTAAAAAC AGCTTGCAAG AAGCATGAGC TCTATGTGAG CTTCCAGGAC 
CTGGGATGGC AGGACTGGAT CATTGCACCC AAAGGCTACG CTGCCAACTA CTGTGATGGA 
GAGTGTTCCT TCCCACTCAA CGCACACATG AATGCCACCA ACCACGCCAT TGTACAGACC 
TTGGTCCACC TTATGAATCC CGAGTACGTC CCCAAACCAT GCTGCGCACC AACCAAACTG 
AATGCCATCT CGGTTCTTTA CTTCGATGAT AACTCCAATG TCATCTTGAA AAAGTACAGG 
AATATGGTCG TGAGAGCTTG TGGTTGCCAT TAA

The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.

RefSeq NP_031582.1
Translation

Target ORF information:

RefSeq Version NM_007556.2
Organism Mus musculus(House mouse)
Definition Mus musculus bone morphogenetic protein 6 (Bmp6), mRNA.

Target ORF information:

Epitope DYKDDDDK
Bacterial selection AMPR
Mammalian selection NeoR
Vector pcDNA3.1+/C-(K)DYK
 NM_007556.2

ORF Insert Sequence:

1
61
121
181
241
301
361
421
481
541
601
661
721
781
841
901
961
1021
1081
1141
1201
1261
1321
1381
1441
1501
ATGCCCGGGC TGGGGCGGAG GGCGCAGTGG CTGTGCTGGT GGTGGGGGTT GCTGTGCAGC 
TGCGGCCCCC CGCCACTGCG GCCCCCTCTG CCGGTAGCCG CGGCCGCCGC CGGGGGGCAG 
CTGCTGGGAG CCGGCGGGAG CCCGGTGCGC GCTGAGCAGC CACCGCCACA GTCCTCTTCT 
TCGGGCTTCC TCTATCGGCG GCTCAAGACC CACGAGAAGC GGGAGATGCA AAAGGAGATC 
CTGTCGGTGC TGGGGCTCCC GCACAGGCCG CGGCCCCTGC ACGGTCTCCA GCAGCCTCAG 
CCCCCGGTGC TCCCGCCACA GCAGCAGCAG CAGCAGCAGC AGCAGCAGAC GGCCCGCGAG 
GAGCCCCCTC CAGGGCGGCT GAAGTCCGCT CCACTCTTCA TGCTGGATCT CTACAACGCC 
CTGTCCAATG ACGACGAAGA GGATGGGGCA TCGGAGGGTG TGGGGCAAGA GCCTGGGTCC 
CACGGAGGGG CCAGCTCGTC CCAGCTCAGG CAGCCGTCTC CCGGCGCTGC ACACTCCTTG 
AACCGCAAGA GTCTCCTGGC CCCGGGACCC GGTGGCGGTG CGTCCCCACT GACTAGCGCG 
CAGGACAGCG CTTTCCTCAA CGACGCGGAC ATGGTCATGA GCTTTGTGAA CCTGGTGGAG 
TACGACAAGG AGTTCTCCCC ACATCAACGA CACCACAAAG AGTTCAAGTT CAACCTATCC 
CAGATTCCTG AGGGTGAGGC GGTGACGGCT GCTGAGTTCC GCGTCTACAA GGACTGTGTG 
GTGGGGAGTT TTAAAAACCA AACCTTTCTT ATCAGCATTT ACCAAGTCTT GCAGGAGCAT 
CAGCACAGAG ACTCTGACCT ATTTTTGTTG GACACCCGGG TGGTGTGGGC CTCAGAAGAA 
GGTTGGCTGG AATTTGACAT CACAGCAACT AGCAATCTGT GGGTGGTGAC ACCGCAGCAC 
AACATGGGGC TCCAGCTGAG TGTGGTGACT CGGGATGGAC TCCACGTCAA CCCCCGTGCG 
GCGGGCCTGG TGGGCAGAGA CGGCCCTTAC GACAAGCAGC CCTTCATGGT GGCCTTCTTC 
AAGGTGAGCG AGGTCCACGT GCGCACCACC AGGTCAGCCT CCAGTCGGCG GCGGCAGCAG 
AGTCGCAACC GGTCCACCCA GTCGCAGGAC GTGTCCCGGG GCTCCGGTTC TTCAGACTAC 
AACGGCAGTG AGTTAAAAAC AGCTTGCAAG AAGCATGAGC TCTATGTGAG CTTCCAGGAC 
CTGGGATGGC AGGACTGGAT CATTGCACCC AAAGGCTACG CTGCCAACTA CTGTGATGGA 
GAGTGTTCCT TCCCACTCAA CGCACACATG AATGCCACCA ACCACGCCAT TGTACAGACC 
TTGGTCCACC TTATGAATCC CGAGTACGTC CCCAAACCAT GCTGCGCACC AACCAAACTG 
AATGCCATCT CGGTTCTTTA CTTCGATGAT AACTCCAATG TCATCTTGAA AAAGTACAGG 
AATATGGTCG TGAGAGCTTG TGGTTGCCAT TAA

The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.

CloneID OMu14173
Clone ID Related Accession (Same CDS sequence) NM_007556.2 , NM_007556.3
Accession Version NM_007556.3 Latest version! Documents for ORF clone product in default vector
Sequence Information ORF Nucleotide Sequence (Length: 1533bp)
Protein sequence
SNP
Vector pcDNA3.1+/C-(K)DYK or customized vector User Manual
Clone information Clone Map MSDS
Tag on pcDNA3.1+/C-(K)DYK C terminal DYKDDDDK tags
ORF Insert Method CloneEZ™ Seamless cloning technology
Insert Structure linear
Update Date 2019-12-03
Organism Mus musculus(house mouse)
Product bone morphogenetic protein 6 preproprotein
Comment Comment: REVIEWED REFSEQ: This record has been curated by NCBI staff. The reference sequence was derived from AC124549.5, AK135770.1 and AK041210.1. On Oct 17, 2015 this sequence version replaced NM_007556.2. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Gene record to access additional publications. ##Evidence-Data-START## Transcript exon combination :: X80992.1, AK135770.1 [ECO:0000332] RNAseq introns :: single sample supports all introns SAMN00849374, SAMN00849375 [ECO:0000348] ##Evidence-Data-END## 

1
61
121
181
241
301
361
421
481
541
601
661
721
781
841
901
961
1021
1081
1141
1201
1261
1321
1381
1441
1501
ATGCCCGGGC TGGGGCGGAG GGCGCAGTGG CTGTGCTGGT GGTGGGGGTT GCTGTGCAGC 
TGCGGCCCCC CGCCACTGCG GCCCCCTCTG CCGGTAGCCG CGGCCGCCGC CGGGGGGCAG 
CTGCTGGGAG CCGGCGGGAG CCCGGTGCGC GCTGAGCAGC CACCGCCACA GTCCTCTTCT 
TCGGGCTTCC TCTATCGGCG GCTCAAGACC CACGAGAAGC GGGAGATGCA AAAGGAGATC 
CTGTCGGTGC TGGGGCTCCC GCACAGGCCG CGGCCCCTGC ACGGTCTCCA GCAGCCTCAG 
CCCCCGGTGC TCCCGCCACA GCAGCAGCAG CAGCAGCAGC AGCAGCAGAC GGCCCGCGAG 
GAGCCCCCTC CAGGGCGGCT GAAGTCCGCT CCACTCTTCA TGCTGGATCT CTACAACGCC 
CTGTCCAATG ACGACGAAGA GGATGGGGCA TCGGAGGGTG TGGGGCAAGA GCCTGGGTCC 
CACGGAGGGG CCAGCTCGTC CCAGCTCAGG CAGCCGTCTC CCGGCGCTGC ACACTCCTTG 
AACCGCAAGA GTCTCCTGGC CCCGGGACCC GGTGGCGGTG CGTCCCCACT GACTAGCGCG 
CAGGACAGCG CTTTCCTCAA CGACGCGGAC ATGGTCATGA GCTTTGTGAA CCTGGTGGAG 
TACGACAAGG AGTTCTCCCC ACATCAACGA CACCACAAAG AGTTCAAGTT CAACCTATCC 
CAGATTCCTG AGGGTGAGGC GGTGACGGCT GCTGAGTTCC GCGTCTACAA GGACTGTGTG 
GTGGGGAGTT TTAAAAACCA AACCTTTCTT ATCAGCATTT ACCAAGTCTT GCAGGAGCAT 
CAGCACAGAG ACTCTGACCT ATTTTTGTTG GACACCCGGG TGGTGTGGGC CTCAGAAGAA 
GGTTGGCTGG AATTTGACAT CACAGCAACT AGCAATCTGT GGGTGGTGAC ACCGCAGCAC 
AACATGGGGC TCCAGCTGAG TGTGGTGACT CGGGATGGAC TCCACGTCAA CCCCCGTGCG 
GCGGGCCTGG TGGGCAGAGA CGGCCCTTAC GACAAGCAGC CCTTCATGGT GGCCTTCTTC 
AAGGTGAGCG AGGTCCACGT GCGCACCACC AGGTCAGCCT CCAGTCGGCG GCGGCAGCAG 
AGTCGCAACC GGTCCACCCA GTCGCAGGAC GTGTCCCGGG GCTCCGGTTC TTCAGACTAC 
AACGGCAGTG AGTTAAAAAC AGCTTGCAAG AAGCATGAGC TCTATGTGAG CTTCCAGGAC 
CTGGGATGGC AGGACTGGAT CATTGCACCC AAAGGCTACG CTGCCAACTA CTGTGATGGA 
GAGTGTTCCT TCCCACTCAA CGCACACATG AATGCCACCA ACCACGCCAT TGTACAGACC 
TTGGTCCACC TTATGAATCC CGAGTACGTC CCCAAACCAT GCTGCGCACC AACCAAACTG 
AATGCCATCT CGGTTCTTTA CTTCGATGAT AACTCCAATG TCATCTTGAA AAAGTACAGG 
AATATGGTCG TGAGAGCTTG TGGTTGCCAT TAA

The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.

RefSeq NP_031582.1
CDS218..1750
Translation

Target ORF information:

RefSeq Version NM_007556.3
Organism Mus musculus(house mouse)
Definition Mus musculus bone morphogenetic protein 6 (Bmp6), mRNA.

Target ORF information:

Epitope DYKDDDDK
Bacterial selection AMPR
Mammalian selection NeoR
Vector pcDNA3.1+/C-(K)DYK
 NM_007556.3

ORF Insert Sequence:

1
61
121
181
241
301
361
421
481
541
601
661
721
781
841
901
961
1021
1081
1141
1201
1261
1321
1381
1441
1501
ATGCCCGGGC TGGGGCGGAG GGCGCAGTGG CTGTGCTGGT GGTGGGGGTT GCTGTGCAGC 
TGCGGCCCCC CGCCACTGCG GCCCCCTCTG CCGGTAGCCG CGGCCGCCGC CGGGGGGCAG 
CTGCTGGGAG CCGGCGGGAG CCCGGTGCGC GCTGAGCAGC CACCGCCACA GTCCTCTTCT 
TCGGGCTTCC TCTATCGGCG GCTCAAGACC CACGAGAAGC GGGAGATGCA AAAGGAGATC 
CTGTCGGTGC TGGGGCTCCC GCACAGGCCG CGGCCCCTGC ACGGTCTCCA GCAGCCTCAG 
CCCCCGGTGC TCCCGCCACA GCAGCAGCAG CAGCAGCAGC AGCAGCAGAC GGCCCGCGAG 
GAGCCCCCTC CAGGGCGGCT GAAGTCCGCT CCACTCTTCA TGCTGGATCT CTACAACGCC 
CTGTCCAATG ACGACGAAGA GGATGGGGCA TCGGAGGGTG TGGGGCAAGA GCCTGGGTCC 
CACGGAGGGG CCAGCTCGTC CCAGCTCAGG CAGCCGTCTC CCGGCGCTGC ACACTCCTTG 
AACCGCAAGA GTCTCCTGGC CCCGGGACCC GGTGGCGGTG CGTCCCCACT GACTAGCGCG 
CAGGACAGCG CTTTCCTCAA CGACGCGGAC ATGGTCATGA GCTTTGTGAA CCTGGTGGAG 
TACGACAAGG AGTTCTCCCC ACATCAACGA CACCACAAAG AGTTCAAGTT CAACCTATCC 
CAGATTCCTG AGGGTGAGGC GGTGACGGCT GCTGAGTTCC GCGTCTACAA GGACTGTGTG 
GTGGGGAGTT TTAAAAACCA AACCTTTCTT ATCAGCATTT ACCAAGTCTT GCAGGAGCAT 
CAGCACAGAG ACTCTGACCT ATTTTTGTTG GACACCCGGG TGGTGTGGGC CTCAGAAGAA 
GGTTGGCTGG AATTTGACAT CACAGCAACT AGCAATCTGT GGGTGGTGAC ACCGCAGCAC 
AACATGGGGC TCCAGCTGAG TGTGGTGACT CGGGATGGAC TCCACGTCAA CCCCCGTGCG 
GCGGGCCTGG TGGGCAGAGA CGGCCCTTAC GACAAGCAGC CCTTCATGGT GGCCTTCTTC 
AAGGTGAGCG AGGTCCACGT GCGCACCACC AGGTCAGCCT CCAGTCGGCG GCGGCAGCAG 
AGTCGCAACC GGTCCACCCA GTCGCAGGAC GTGTCCCGGG GCTCCGGTTC TTCAGACTAC 
AACGGCAGTG AGTTAAAAAC AGCTTGCAAG AAGCATGAGC TCTATGTGAG CTTCCAGGAC 
CTGGGATGGC AGGACTGGAT CATTGCACCC AAAGGCTACG CTGCCAACTA CTGTGATGGA 
GAGTGTTCCT TCCCACTCAA CGCACACATG AATGCCACCA ACCACGCCAT TGTACAGACC 
TTGGTCCACC TTATGAATCC CGAGTACGTC CCCAAACCAT GCTGCGCACC AACCAAACTG 
AATGCCATCT CGGTTCTTTA CTTCGATGAT AACTCCAATG TCATCTTGAA AAAGTACAGG 
AATATGGTCG TGAGAGCTTG TGGTTGCCAT TAA

The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.

PubMed