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WNT16 cDNA ORF clone, Homo sapiens(human)

Summary

Gene Symbol WNT16
Entrez Gene ID 51384
Full Name Wnt family member 16
General protein information
Preferred Names

Wnt family member 16

Names

protein Wnt-16
wingless-type MMTV integration site family member 16b
wingless-type MMTV integration site family, member 16
Gene Type protein-coding
Organism Homo sapiens(human)
Genome

7

7q31.31
Summary The WNT gene family consists of structurally related genes which encode secreted signaling proteins. These proteins have been implicated in oncogenesis and in several developmental processes, including regulation of cell fate and patterning during embryogenesis. This gene is a member of the WNT gene family. It contains two transcript variants diverging at the 5' termini. These two variants are proposed to be the products of separate promoters and not to be splice variants from a single promoter. They are differentially expressed in normal tissues, one of which (variant 2) is expressed at significant levels only in the pancreas, whereas another one (variant 1) is expressed more ubiquitously with highest levels in adult kidney, placenta, brain, heart, and spleen. [provided by RefSeq, Jul 2008].
Disorder MIM:

606267


Reference Sequences (RefSeq)

mRNA and Protein(s)

mRNA Protein Name
NM_057168.2 NP_476509.1 protein Wnt-16 isoform 1 precursor
NM_016087.2 NP_057171.2 protein Wnt-16 isoform 2
NM_057168.1 NP_476509.1 protein Wnt-16 isoform 1 precursor

Pathways from BioSystems


Homologies


Bos taurus (cattle) WNT16 NP_001014949.1
Caenorhabditis elegans (roundworm) egl-20 NP_501754.1
Gallus gallus (chicken) WNT16 XP_001233678.3
Homo sapiens (human) WNT16 NP_476509.1
Pan troglodytes (chimpanzee) WNT16 XP_001143972.1
WNT16 XP_001082781.1
Mus musculus (house mouse) Wnt16 NP_444346.3
Rattus norvegicus (Norway rat) Wnt16 NP_001102693.1
Danio rerio (zebrafish) wnt16 NP_001093516.1
Xenopus tropicalis (tropical clawed frog) wnt16 NP_001096551.1

Gene Ontology


Bibliography

Related articles in PubMed

Non-synonymous WNT16 polymorphisms alleles are associated with different osteoarthritis phenotypes.
Garc?a-Ibarbia C, Neila S, Garc?s C, Alonso MA, Zarrabeitia MT, Valero C, Ortiz F, Riancho JA
Rheumatology international37(10)1667-1672(2017 Oct)

Altered Expression of PRKX, WNT3 and WNT16 in Human Nodular Basal Cell Carcinoma.
DO Carmo NG, Sakamoto LH, Pogue R, DO Couto Mascarenhas C, Passos SK, Felipe MS, DE Andrade RV
Anticancer research36(9)4545-51(2016 09)

Bone morphogenetic protein-induced cell differentiation involves Atg7 and Wnt16 sequentially in human stem cell-derived osteoblastic cells.
Ozeki N, Mogi M, Hase N, Hiyama T, Yamaguchi H, Kawai R, Matsumoto T, Nakata K
Experimental cell research347(1)24-41(2016 09)

GeneRIFs: Gene References Into Functions What's a GeneRIF?

PRKX, WNT3 and WNT16 genes, belonging to the WNT signaling pathway, are involved in the tumorigenic process of nodular basal cell carcinoma
Title: Altered Expression of PRKX, WNT3 and WNT16 in Human Nodular Basal Cell Carcinoma.

the upregulation of autophagy-related gene (Atg) and wingless/int1 (Wnt) signaling during BMP-2-mediated human osteoblastic differentiation, was examined.
Title: Bone morphogenetic protein-induced cell differentiation involves Atg7 and Wnt16 sequentially in human stem cell-derived osteoblastic cells.

WNT16B recognizes cancer cell surface receptors including frizzled (FZD) 3/4/6, a process enhanced by SFRP2, coordinated by the co-receptor LRP6 but subject to abrogation by DKK1.
Title: SFRP2 augments WNT16B signaling to promote therapeutic resistance in the damaged tumor microenvironment.

Data indicate that WNT16 is critical for positive regulation of both cortical and trabecular bone mass and structure. WNT16-TG mice exhibited significantly higher whole-body areal bone mineral density and bone mineral content.
Title: Osteoblast-Specific Overexpression of Human WNT16 Increases Both Cortical and Trabecular Bone Mass and Structure in Mice.

loss of endogenous WNT16 results specifically in cortical bone loss, whereas overexpression of WNT16 surprisingly increases mainly trabecular bone mass.
Title: The bone-sparing effects of estrogen and WNT16 are independent of each other.

The following WNT16 gene cDNA ORF clone sequences were retrieved from the NCBI Reference Sequence Database (RefSeq). These sequences represent the protein coding region of the WNT16 cDNA ORF which is encoded by the open reading frame (ORF) sequence. ORF sequences can be delivered in our standard vector, pcDNA3.1+/C-(K)DYK or the vector of your choice as an expression/transfection-ready ORF clone. Not the clone you want? Click here to find your clone.

***CloneID Accession No. Definition **Vector *Turnaround time Price (USD) Select
OHu13041 NM_057168.2
Latest version!		 Homo sapiens Wnt family member 16 (WNT16), transcript variant 1, mRNA. pcDNA3.1-C-(k)DYK or customized vector
in pcDNA3.1-C-(k)DYK 		$189.50-$265.30
$379.00
OHu19019 NM_016087.2
Latest version!		 Homo sapiens Wnt family member 16 (WNT16), transcript variant 2, mRNA. pcDNA3.1-C-(k)DYK or customized vector 7-9 $202.30
$289.00
View Old Accession Versions >>
OHu13041 NM_057168.1 Homo sapiens Wnt family member 16 (WNT16), transcript variant 1, mRNA. pcDNA3.1-C-(k)DYK or customized vector
in pcDNA3.1-C-(k)DYK 		$189.50-$265.30
$379.00
Hide Old Accession Versions >>

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** You may select a custom vector to replace pcDNA3.1+/C-(K)DYK after clone is added to cart.

** GenScript guarantees 100% sequence accuracy of all synthetic DNA constructs we deliver, but we do not guarantee protein expression in your experimental system. Protein expression is influenced by many factors that may vary between experiments or laboratories. In addition, please pay attention to the signal peptide, propeptide and transit peptide in target ORF, which may affect the choice of vector (N/C terminal tag vector).

***One clone ID might be correlated to multiple accession numbers, which share the same CDS sequence.

Reference Sequences (Refseq)


CloneID OHu13041
Clone ID Related Accession (Same CDS sequence) NM_057168.2 , NM_057168.1
Accession Version NM_057168.2 Latest version! Documents for ORF clone product in default vector
Sequence Information ORF Nucleotide Sequence (Length: 1098bp)
Protein sequence
SNP
Vector pcDNA3.1+/C-(K)DYK or customized vector User Manual
Clone information Clone Map MSDS
Tag on pcDNA3.1+/C-(K)DYK C terminal DYKDDDDK tags
ORF Insert Method CloneEZ™ Seamless cloning technology
Insert Structure linear
Update Date 2020-01-01
Organism Homo sapiens(human)
Product protein Wnt-16 isoform 1 precursor
Comment Comment: REVIEWED REFSEQ: This record has been curated by NCBI staff. The reference sequence was derived from AC006364.4. On Nov 26, 2018 this sequence version replaced NM_057168.1. Transcript Variant: This variant (1) differs from variant 2 at the 5' terminus including 5' UTR and the coding region for the N-terminus. Isoform 1, encoded by this variant, is 90% identical to the mouse Wnt16 protein at the amino acid level. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Gene record to access additional publications. ##Evidence-Data-START## Transcript exon combination :: AF169963.1, BC104945.1 [ECO:0000332] ##Evidence-Data-END## ##RefSeq-Attributes-START## MANE Ensembl match :: ENST00000222462.3/ ENSP00000222462.2 RefSeq Select criteria :: based on conservation, expression, longest protein ##RefSeq-Attributes-END## COMPLETENESS: full length. 

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ATGGACAGGG CGGCGCTCCT GGGACTGGCC CGCTTGTGCG CGCTGTGGGC AGCCCTGCTC 
GTGCTGTTCC CCTACGGAGC CCAAGGAAAC TGGATGTGGT TGGGCATTGC CTCCTTCGGG 
GTTCCAGAGA AGCTGGGCTG CGCCAATTTG CCGCTGAACA GCCGCCAGAA GGAGCTGTGC 
AAGAGGAAAC CGTACCTGCT GCCGAGCATC CGAGAGGGCG CCCGGCTGGG CATTCAGGAG 
TGCGGGAGCC AGTTCAGACA CGAGAGATGG AACTGCATGA TCACCGCCGC CGCCACTACC 
GCCCCGATGG GCGCCAGCCC CCTCTTTGGC TACGAGCTGA GCAGCGGCAC CAAAGAGACA 
GCATTTATTT ATGCTGTGAT GGCTGCAGGC CTGGTGCATT CTGTGACCAG GTCATGCAGT 
GCAGGCAACA TGACAGAGTG TTCCTGTGAC ACCACCTTGC AGAACGGCGG CTCAGCAAGT 
GAAGGCTGGC ACTGGGGGGG CTGCTCCGAT GATGTCCAGT ATGGCATGTG GTTCAGCAGA 
AAGTTCCTAG ATTTCCCCAT CGGAAACACC ACGGGCAAAG AAAACAAAGT ACTATTAGCA 
ATGAACCTAC ATAACAATGA AGCTGGAAGG CAGGCTGTCG CCAAGTTGAT GTCAGTAGAC 
TGCCGCTGCC ACGGAGTTTC CGGCTCCTGT GCTGTGAAAA CATGCTGGAA AACCATGTCT 
TCTTTTGAAA AGATTGGCCA TTTGTTGAAG GATAAATATG AAAACAGTAT CCAGATATCA 
GACAAAACAA AGAGGAAAAT GCGCAGGAGA GAAAAAGATC AGAGGAAAAT ACCAATCCAT 
AAGGATGATC TGCTCTATGT TAATAAGTCT CCCAACTACT GTGTAGAAGA TAAGAAACTG 
GGAATCCCAG GGACACAAGG CAGAGAATGC AACCGTACAT CAGAGGGTGC AGATGGCTGC 
AACCTCCTCT GCTGTGGCCG AGGTTACAAC ACCCATGTGG TCAGGCACGT GGAGAGGTGT 
GAGTGTAAGT TCATCTGGTG CTGCTATGTC CGTTGCAGGA GGTGTGAAAG CATGACTGAT 
GTCCACACTT GCAAGTAA

The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.

RefSeq NP_476509.1
CDS294..1391
Translation

Target ORF information:

RefSeq Version NM_057168.2
Organism Homo sapiens(human)
Definition Homo sapiens Wnt family member 16 (WNT16), transcript variant 1, mRNA.

Target ORF information:

Epitope DYKDDDDK
Bacterial selection AMPR
Mammalian selection NeoR
Vector pcDNA3.1+/C-(K)DYK
 NM_057168.2

ORF Insert Sequence:

1
61
121
181
241
301
361
421
481
541
601
661
721
781
841
901
961
1021
1081
ATGGACAGGG CGGCGCTCCT GGGACTGGCC CGCTTGTGCG CGCTGTGGGC AGCCCTGCTC 
GTGCTGTTCC CCTACGGAGC CCAAGGAAAC TGGATGTGGT TGGGCATTGC CTCCTTCGGG 
GTTCCAGAGA AGCTGGGCTG CGCCAATTTG CCGCTGAACA GCCGCCAGAA GGAGCTGTGC 
AAGAGGAAAC CGTACCTGCT GCCGAGCATC CGAGAGGGCG CCCGGCTGGG CATTCAGGAG 
TGCGGGAGCC AGTTCAGACA CGAGAGATGG AACTGCATGA TCACCGCCGC CGCCACTACC 
GCCCCGATGG GCGCCAGCCC CCTCTTTGGC TACGAGCTGA GCAGCGGCAC CAAAGAGACA 
GCATTTATTT ATGCTGTGAT GGCTGCAGGC CTGGTGCATT CTGTGACCAG GTCATGCAGT 
GCAGGCAACA TGACAGAGTG TTCCTGTGAC ACCACCTTGC AGAACGGCGG CTCAGCAAGT 
GAAGGCTGGC ACTGGGGGGG CTGCTCCGAT GATGTCCAGT ATGGCATGTG GTTCAGCAGA 
AAGTTCCTAG ATTTCCCCAT CGGAAACACC ACGGGCAAAG AAAACAAAGT ACTATTAGCA 
ATGAACCTAC ATAACAATGA AGCTGGAAGG CAGGCTGTCG CCAAGTTGAT GTCAGTAGAC 
TGCCGCTGCC ACGGAGTTTC CGGCTCCTGT GCTGTGAAAA CATGCTGGAA AACCATGTCT 
TCTTTTGAAA AGATTGGCCA TTTGTTGAAG GATAAATATG AAAACAGTAT CCAGATATCA 
GACAAAACAA AGAGGAAAAT GCGCAGGAGA GAAAAAGATC AGAGGAAAAT ACCAATCCAT 
AAGGATGATC TGCTCTATGT TAATAAGTCT CCCAACTACT GTGTAGAAGA TAAGAAACTG 
GGAATCCCAG GGACACAAGG CAGAGAATGC AACCGTACAT CAGAGGGTGC AGATGGCTGC 
AACCTCCTCT GCTGTGGCCG AGGTTACAAC ACCCATGTGG TCAGGCACGT GGAGAGGTGT 
GAGTGTAAGT TCATCTGGTG CTGCTATGTC CGTTGCAGGA GGTGTGAAAG CATGACTGAT 
GTCCACACTT GCAAGTAA

The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.

CloneID OHu13041
Clone ID Related Accession (Same CDS sequence) NM_057168.2 , NM_057168.1
Accession Version NM_057168.1 Documents for ORF clone product in default vector
Sequence Information ORF Nucleotide Sequence (Length: 1098bp)
Protein sequence
SNP
Vector pcDNA3.1+/C-(K)DYK or customized vector User Manual
Clone information Clone Map MSDS
Tag on pcDNA3.1+/C-(K)DYK C terminal DYKDDDDK tags
ORF Insert Method CloneEZ™ Seamless cloning technology
Insert Structure linear
Update Date 2017-09-09
Organism Homo sapiens(human)
Product protein Wnt-16 isoform 1 precursor
Comment Comment: REVIEWED REFSEQ: This record has been curated by NCBI staff. The reference sequence was derived from AF169963.1. Transcript Variant: This variant (1) differs from variant 2 at the 5' terminus including 5' UTR and the coding region for the N-terminus. Isoform 1, encoded by this variant, is 90% identical to the mouse Wnt16 protein at the amino acid level. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Gene record to access additional publications. ##Evidence-Data-START## Transcript exon combination :: AF169963.1, SRR1660803.242393.1 [ECO:0000332] RNAseq introns :: single sample supports all introns SAMEA2145893, SAMEA2147596 [ECO:0000348] ##Evidence-Data-END## COMPLETENESS: complete on the 3' end. 

1
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181
241
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361
421
481
541
601
661
721
781
841
901
961
1021
1081
ATGGACAGGG CGGCGCTCCT GGGACTGGCC CGCTTGTGCG CGCTGTGGGC AGCCCTGCTC 
GTGCTGTTCC CCTACGGAGC CCAAGGAAAC TGGATGTGGT TGGGCATTGC CTCCTTCGGG 
GTTCCAGAGA AGCTGGGCTG CGCCAATTTG CCGCTGAACA GCCGCCAGAA GGAGCTGTGC 
AAGAGGAAAC CGTACCTGCT GCCGAGCATC CGAGAGGGCG CCCGGCTGGG CATTCAGGAG 
TGCGGGAGCC AGTTCAGACA CGAGAGATGG AACTGCATGA TCACCGCCGC CGCCACTACC 
GCCCCGATGG GCGCCAGCCC CCTCTTTGGC TACGAGCTGA GCAGCGGCAC CAAAGAGACA 
GCATTTATTT ATGCTGTGAT GGCTGCAGGC CTGGTGCATT CTGTGACCAG GTCATGCAGT 
GCAGGCAACA TGACAGAGTG TTCCTGTGAC ACCACCTTGC AGAACGGCGG CTCAGCAAGT 
GAAGGCTGGC ACTGGGGGGG CTGCTCCGAT GATGTCCAGT ATGGCATGTG GTTCAGCAGA 
AAGTTCCTAG ATTTCCCCAT CGGAAACACC ACGGGCAAAG AAAACAAAGT ACTATTAGCA 
ATGAACCTAC ATAACAATGA AGCTGGAAGG CAGGCTGTCG CCAAGTTGAT GTCAGTAGAC 
TGCCGCTGCC ACGGAGTTTC CGGCTCCTGT GCTGTGAAAA CATGCTGGAA AACCATGTCT 
TCTTTTGAAA AGATTGGCCA TTTGTTGAAG GATAAATATG AAAACAGTAT CCAGATATCA 
GACAAAACAA AGAGGAAAAT GCGCAGGAGA GAAAAAGATC AGAGGAAAAT ACCAATCCAT 
AAGGATGATC TGCTCTATGT TAATAAGTCT CCCAACTACT GTGTAGAAGA TAAGAAACTG 
GGAATCCCAG GGACACAAGG CAGAGAATGC AACCGTACAT CAGAGGGTGC AGATGGCTGC 
AACCTCCTCT GCTGTGGCCG AGGTTACAAC ACCCATGTGG TCAGGCACGT GGAGAGGTGT 
GAGTGTAAGT TCATCTGGTG CTGCTATGTC CGTTGCAGGA GGTGTGAAAG CATGACTGAT 
GTCCACACTT GCAAGTAA

The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.

RefSeq NP_476509.1
CDS258..1355
Translation

Target ORF information:

RefSeq Version NM_057168.1
Organism Homo sapiens(human)
Definition Homo sapiens Wnt family member 16 (WNT16), transcript variant 1, mRNA.

Target ORF information:

Epitope DYKDDDDK
Bacterial selection AMPR
Mammalian selection NeoR
Vector pcDNA3.1+/C-(K)DYK
 NM_057168.1

ORF Insert Sequence:

1
61
121
181
241
301
361
421
481
541
601
661
721
781
841
901
961
1021
1081
ATGGACAGGG CGGCGCTCCT GGGACTGGCC CGCTTGTGCG CGCTGTGGGC AGCCCTGCTC 
GTGCTGTTCC CCTACGGAGC CCAAGGAAAC TGGATGTGGT TGGGCATTGC CTCCTTCGGG 
GTTCCAGAGA AGCTGGGCTG CGCCAATTTG CCGCTGAACA GCCGCCAGAA GGAGCTGTGC 
AAGAGGAAAC CGTACCTGCT GCCGAGCATC CGAGAGGGCG CCCGGCTGGG CATTCAGGAG 
TGCGGGAGCC AGTTCAGACA CGAGAGATGG AACTGCATGA TCACCGCCGC CGCCACTACC 
GCCCCGATGG GCGCCAGCCC CCTCTTTGGC TACGAGCTGA GCAGCGGCAC CAAAGAGACA 
GCATTTATTT ATGCTGTGAT GGCTGCAGGC CTGGTGCATT CTGTGACCAG GTCATGCAGT 
GCAGGCAACA TGACAGAGTG TTCCTGTGAC ACCACCTTGC AGAACGGCGG CTCAGCAAGT 
GAAGGCTGGC ACTGGGGGGG CTGCTCCGAT GATGTCCAGT ATGGCATGTG GTTCAGCAGA 
AAGTTCCTAG ATTTCCCCAT CGGAAACACC ACGGGCAAAG AAAACAAAGT ACTATTAGCA 
ATGAACCTAC ATAACAATGA AGCTGGAAGG CAGGCTGTCG CCAAGTTGAT GTCAGTAGAC 
TGCCGCTGCC ACGGAGTTTC CGGCTCCTGT GCTGTGAAAA CATGCTGGAA AACCATGTCT 
TCTTTTGAAA AGATTGGCCA TTTGTTGAAG GATAAATATG AAAACAGTAT CCAGATATCA 
GACAAAACAA AGAGGAAAAT GCGCAGGAGA GAAAAAGATC AGAGGAAAAT ACCAATCCAT 
AAGGATGATC TGCTCTATGT TAATAAGTCT CCCAACTACT GTGTAGAAGA TAAGAAACTG 
GGAATCCCAG GGACACAAGG CAGAGAATGC AACCGTACAT CAGAGGGTGC AGATGGCTGC 
AACCTCCTCT GCTGTGGCCG AGGTTACAAC ACCCATGTGG TCAGGCACGT GGAGAGGTGT 
GAGTGTAAGT TCATCTGGTG CTGCTATGTC CGTTGCAGGA GGTGTGAAAG CATGACTGAT 
GTCCACACTT GCAAGTAA

The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.

CloneID OHu19019
Clone ID Related Accession (Same CDS sequence) NM_016087.2
Accession Version NM_016087.2 Latest version! Documents for ORF clone product in default vector
Sequence Information ORF Nucleotide Sequence (Length: 1068bp)
Protein sequence
SNP
Vector pcDNA3.1+/C-(K)DYK or customized vector User Manual
Clone information Clone Map MSDS
Tag on pcDNA3.1+/C-(K)DYK C terminal DYKDDDDK tags
ORF Insert Method CloneEZ™ Seamless cloning technology
Insert Structure linear
Update Date 2019-12-03
Organism Homo sapiens(human)
Product protein Wnt-16 isoform 2
Comment Comment: REVIEWED REFSEQ: This record has been curated by NCBI staff. The reference sequence was derived from AF152584.1 and AF169963.1. This sequence is a reference standard in the RefSeqGene project. On Dec 7, 2001 this sequence version replaced NM_016087.1. Transcript Variant: This variant (2) differs from variant 1 at the 5' terminus including 5' UTR and the coding region for the N-terminus. It encodes a shorter isoform than variant 1. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Gene record to access additional publications. ##Evidence-Data-START## Transcript exon combination :: AF152584.1 [ECO:0000332] ##Evidence-Data-END## ##RefSeq-Attributes-START## regulatory uORF :: PMID: 23617586 ##RefSeq-Attributes-END## COMPLETENESS: complete on the 3' end. 

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ATGCAGCTCA CCACTTGCCT CAGGGAGACC CTCTTCACAG GGGCTTCTCA AAAGACCTCC 
CTATGGTGGT TGGGCATTGC CTCCTTCGGG GTTCCAGAGA AGCTGGGCTG CGCCAATTTG 
CCGCTGAACA GCCGCCAGAA GGAGCTGTGC AAGAGGAAAC CGTACCTGCT GCCGAGCATC 
CGAGAGGGCG CCCGGCTGGG CATTCAGGAG TGCGGGAGCC AGTTCAGACA CGAGAGATGG 
AACTGCATGA TCACCGCCGC CGCCACTACC GCCCCGATGG GCGCCAGCCC CCTCTTTGGC 
TACGAGCTGA GCAGCGGCAC CAAAGAGACA GCATTTATTT ATGCTGTGAT GGCTGCAGGC 
CTGGTGCATT CTGTGACCAG GTCATGCAGT GCAGGCAACA TGACAGAGTG TTCCTGTGAC 
ACCACCTTGC AGAACGGCGG CTCAGCAAGT GAAGGCTGGC ACTGGGGGGG CTGCTCCGAT 
GATGTCCAGT ATGGCATGTG GTTCAGCAGA AAGTTCCTAG ATTTCCCCAT CGGAAACACC 
ACGGGCAAAG AAAACAAAGT ACTATTAGCA ATGAACCTAC ATAACAATGA AGCTGGAAGG 
CAGGCTGTCG CCAAGTTGAT GTCAGTAGAC TGCCGCTGCC ACGGAGTTTC CGGCTCCTGT 
GCTGTGAAAA CATGCTGGAA AACCATGTCT TCTTTTGAAA AGATTGGCCA TTTGTTGAAG 
GATAAATATG AAAACAGTAT CCAGATATCA GACAAAACAA AGAGGAAAAT GCGCAGGAGA 
GAAAAAGATC AGAGGAAAAT ACCAATCCAT AAGGATGATC TGCTCTATGT TAATAAGTCT 
CCCAACTACT GTGTAGAAGA TAAGAAACTG GGAATCCCAG GGACACAAGG CAGAGAATGC 
AACCGTACAT CAGAGGGTGC AGATGGCTGC AACCTCCTCT GCTGTGGCCG AGGTTACAAC 
ACCCATGTGG TCAGGCACGT GGAGAGGTGT GAGTGTAAGT TCATCTGGTG CTGCTATGTC 
CGTTGCAGGA GGTGTGAAAG CATGACTGAT GTCCACACTT GCAAGTAA

The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.

RefSeq NP_057171.2
CDS50..1117
Translation

Target ORF information:

RefSeq Version NM_016087.2
Organism Homo sapiens(human)
Definition Homo sapiens Wnt family member 16 (WNT16), transcript variant 2, mRNA.

Target ORF information:

Epitope DYKDDDDK
Bacterial selection AMPR
Mammalian selection NeoR
Vector pcDNA3.1+/C-(K)DYK
 NM_016087.2

ORF Insert Sequence:

1
61
121
181
241
301
361
421
481
541
601
661
721
781
841
901
961
1021
ATGCAGCTCA CCACTTGCCT CAGGGAGACC CTCTTCACAG GGGCTTCTCA AAAGACCTCC 
CTATGGTGGT TGGGCATTGC CTCCTTCGGG GTTCCAGAGA AGCTGGGCTG CGCCAATTTG 
CCGCTGAACA GCCGCCAGAA GGAGCTGTGC AAGAGGAAAC CGTACCTGCT GCCGAGCATC 
CGAGAGGGCG CCCGGCTGGG CATTCAGGAG TGCGGGAGCC AGTTCAGACA CGAGAGATGG 
AACTGCATGA TCACCGCCGC CGCCACTACC GCCCCGATGG GCGCCAGCCC CCTCTTTGGC 
TACGAGCTGA GCAGCGGCAC CAAAGAGACA GCATTTATTT ATGCTGTGAT GGCTGCAGGC 
CTGGTGCATT CTGTGACCAG GTCATGCAGT GCAGGCAACA TGACAGAGTG TTCCTGTGAC 
ACCACCTTGC AGAACGGCGG CTCAGCAAGT GAAGGCTGGC ACTGGGGGGG CTGCTCCGAT 
GATGTCCAGT ATGGCATGTG GTTCAGCAGA AAGTTCCTAG ATTTCCCCAT CGGAAACACC 
ACGGGCAAAG AAAACAAAGT ACTATTAGCA ATGAACCTAC ATAACAATGA AGCTGGAAGG 
CAGGCTGTCG CCAAGTTGAT GTCAGTAGAC TGCCGCTGCC ACGGAGTTTC CGGCTCCTGT 
GCTGTGAAAA CATGCTGGAA AACCATGTCT TCTTTTGAAA AGATTGGCCA TTTGTTGAAG 
GATAAATATG AAAACAGTAT CCAGATATCA GACAAAACAA AGAGGAAAAT GCGCAGGAGA 
GAAAAAGATC AGAGGAAAAT ACCAATCCAT AAGGATGATC TGCTCTATGT TAATAAGTCT 
CCCAACTACT GTGTAGAAGA TAAGAAACTG GGAATCCCAG GGACACAAGG CAGAGAATGC 
AACCGTACAT CAGAGGGTGC AGATGGCTGC AACCTCCTCT GCTGTGGCCG AGGTTACAAC 
ACCCATGTGG TCAGGCACGT GGAGAGGTGT GAGTGTAAGT TCATCTGGTG CTGCTATGTC 
CGTTGCAGGA GGTGTGAAAG CATGACTGAT GTCCACACTT GCAAGTAA

The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.

PubMed

book

Non-synonymous WNT16 polymorphisms alleles are associated with different osteoarthritis phenotypes.
Rheumatology international37(10)1667-1672(2017 Oct)
Garc?a-Ibarbia C,Neila S,Garc?s C,Alonso MA,Zarrabeitia MT,Valero C,Ortiz F,Riancho JA


book

Altered Expression of PRKX, WNT3 and WNT16 in Human Nodular Basal Cell Carcinoma.
Anticancer research36(9)4545-51(2016 09)
DO Carmo NG,Sakamoto LH,Pogue R,DO Couto Mascarenhas C,Passos SK,Felipe MS,DE Andrade RV


book

Bone morphogenetic protein-induced cell differentiation involves Atg7 and Wnt16 sequentially in human stem cell-derived osteoblastic cells.
Experimental cell research347(1)24-41(2016 09)
Ozeki N,Mogi M,Hase N,Hiyama T,Yamaguchi H,Kawai R,Matsumoto T,Nakata K