Gene Symbol | Adh5 |
Entrez Gene ID | 100145871 |
Full Name | alcohol dehydrogenase 5 (class III), chi polypeptide |
General protein information |
|
Gene Type | protein-coding |
Organism | Rattus norvegicus(Norway rat) |
Genome |
ORF » Species Summary » Rattus norvegicus » Adh5 cDNA ORF clone
gRNAs
Gene Symbol | Adh5 |
Entrez Gene ID | 100145871 |
Full Name | alcohol dehydrogenase 5 (class III), chi polypeptide |
General protein information |
|
Gene Type | protein-coding |
Organism | Rattus norvegicus(Norway rat) |
Genome |
mRNA | Protein | Name |
---|---|---|
NM_001126120.1 | NP_001119592.1 | alcohol dehydrogenase class-3 |
Bos taurus (cattle) | ADH5 | NP_001029421.1 |
Eremothecium gossypii | AGOS_ACL148C | NP_983256.1 |
Schizosaccharomyces pombe (fission yeast) | SPCC13B11.04c | NP_588247.1 |
Xenopus tropicalis (tropical clawed frog) | adh5 | NP_001011502.1 |
Canis lupus familiaris (dog) | ADH5 | NP_001239084.1 |
Saccharomyces cerevisiae (baker's yeast) | SFA1 | NP_010113.1 |
Kluyveromyces lactis | KLLA0D12342g | XP_453612.1 |
Oryza sativa (rice) | Os02g0815500 | NP_001048503.1 |
Homo sapiens (human) | ADH5 | NP_000662.3 |
Pan troglodytes (chimpanzee) | ADH5 | XP_001166206.1 |
Mus musculus (house mouse) | Adh5 | NP_031436.2 |
Rattus norvegicus (Norway rat) | Adh5 | NP_001119592.1 |
Gallus gallus (chicken) | ADH5 | NP_001026323.1 |
Caenorhabditis elegans (roundworm) | H24K24.3 | NP_001024016.1 |
Caenorhabditis elegans (roundworm) | Y50D4C.2 | NP_503357.1 |
Magnaporthe oryzae (rice blast fungus) | MGG_06011 | XP_003711858.1 |
LOC697703 | XP_001088376.1 | |
Danio rerio (zebrafish) | adh5 | NP_571924.2 |
Drosophila melanogaster (fruit fly) | Fdh | NP_524310.1 |
Anopheles gambiae (African malaria mosquito) | AgaP_AGAP010499 | XP_314472.4 |
Neurospora crassa | NCU06652 | XP_960697.1 |
Arabidopsis thaliana (thale cress) | HOT5 | NP_199207.1 |
Nebivolol Acts as a S-Nitrosoglutathione Reductase Inhibitor: A New Mechanism of Action.
Jiang H, Polhemus DJ, Islam KN, Torregrossa AC, Li Z, Potts A, Lefer DJ, Bryan NS
Journal of cardiovascular pharmacology and therapeutics21(5)478-85(2016 Sep)
Activation of GSNOR transcription by NF-?B negatively regulates NGF-induced PC12 differentiation.
Wu K, Zhang Y, Wang P, Zhang L, Wang T, Chen C
Free radical research48(9)1011-7(2014 Sep)
Analysis of mammalian alcohol dehydrogenase 5 (ADH5): characterisation of rat ADH5 with comparisons to the corresponding human variant.
Ostberg LJ, Str?mberg P, Hedberg JJ, Persson B, H??g JO
Chemico-biological interactions202(1-3)97-103(2013 Feb)
Inhibition of nitric oxide synthesis during induced cholestasis ameliorates hepatocellular injury by facilitating S-nitrosothiol homeostasis.
L?pez-S?nchez LM, Corrales FJ, Barcos M, Espejo I, Mu?oz-Casta?eda JR, Rodr?guez-Ariza A
Laboratory investigation; a journal of technical methods and pathology90(1)116-27(2010 Jan)
Increased nitrosoglutathione reductase activity in hypoxic pulmonary hypertension in mice.
Wu X, Du L, Xu X, Tan L, Li R
Journal of pharmacological sciences113(1)32-40(2010)
GeneRIFs: Gene References Into Functions What's a GeneRIF?
Report inhibition of GSNOR activity by nebivolol leading to accumulation of nitrosothiols in cells, and this is associated with an enhanced vasodilation by S-nitrosoglutathione.
Title: Nebivolol Acts as a S-Nitrosoglutathione Reductase Inhibitor: A New Mechanism of Action.
We have defined a novel role of GSNOR in neurite development and provide molecular insights into the control of neurite growth.
Title: Activation of GSNOR transcription by NF-?B negatively regulates NGF-induced PC12 differentiation.
ADH5, while readily expressed at the mRNA level, does not behave similarly to other mammalian ADHs investigated.
Title: Analysis of mammalian alcohol dehydrogenase 5 (ADH5): characterisation of rat ADH5 with comparisons to the corresponding human variant.
The following Adh5 gene cDNA ORF clone sequences were retrieved from the NCBI Reference Sequence Database (RefSeq). These sequences represent the protein coding region of the Adh5 cDNA ORF which is encoded by the open reading frame (ORF) sequence. ORF sequences can be delivered in our standard vector, pcDNA3.1+/C-(K)DYK or the vector of your choice as an expression/transfection-ready ORF clone. Not the clone you want? Click here to find your clone.
CloneID | ORa01339 | |
Clone ID Related Accession (Same CDS sequence) | NM_001126120.1 | |
Accession Version | NM_001126120.1 Latest version! | Documents for ORF clone product in default vector |
Sequence Information | ORF Nucleotide Sequence (Length: 1125bp) Protein sequence SNP |
|
Vector | pcDNA3.1-C-(k)DYK or customized vector | ![]() |
Clone information | Clone Map | ![]() |
Tag on pcDNA3.1+/C-(K)DYK | C terminal DYKDDDDK tags | |
ORF Insert Method | CloneEZ™ Seamless cloning technology | |
Insert Structure | linear | |
Update Date | 2019-12-27 | |
Organism | Rattus norvegicus(Norway rat) | |
Product | alcohol dehydrogenase class-3 | |
Comment | Comment: PROVISIONAL REFSEQ: This record has not yet been subject to final NCBI review. The reference sequence was derived from BC083724.1. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Gene record to access additional publications. ##Evidence-Data-START## Transcript exon combination :: BC083724.1, FQ212535.1 [ECO:0000332] RNAseq introns :: single sample supports all introns SAMD00052296, SAMD00052297 [ECO:0000348] ##Evidence-Data-END## |
1 | ATGGCGAACC AGGTGATCAG GTGTAAGGCT GCAGTCGCCT GGGAGGCCGG AAAGCCTCTC |
The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.
RefSeq | NP_001119592.1 |
CDS | 16..1140 |
Translation |
Target ORF information:
Target ORF information:
|
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1 | ATGGCGAACC AGGTGATCAG GTGTAAGGCT GCAGTCGCCT GGGAGGCCGG AAAGCCTCTC |
The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.
Nebivolol Acts as a S-Nitrosoglutathione Reductase Inhibitor: A New Mechanism of Action. |
Activation of GSNOR transcription by NF-?B negatively regulates NGF-induced PC12 differentiation. |
Analysis of mammalian alcohol dehydrogenase 5 (ADH5): characterisation of rat ADH5 with comparisons to the corresponding human variant. |
Inhibition of nitric oxide synthesis during induced cholestasis ameliorates hepatocellular injury by facilitating S-nitrosothiol homeostasis. |
Increased nitrosoglutathione reductase activity in hypoxic pulmonary hypertension in mice. |