Gene Symbol | Styx |
Entrez Gene ID | 100912536 |
Full Name | serine/threonine/tyrosine interacting protein |
General protein information |
|
Gene Type | protein-coding |
Organism | Rattus norvegicus(Norway rat) |
Genome |
ORF » Species Summary » Rattus norvegicus » Styx cDNA ORF clone
Gene Symbol | Styx |
Entrez Gene ID | 100912536 |
Full Name | serine/threonine/tyrosine interacting protein |
General protein information |
|
Gene Type | protein-coding |
Organism | Rattus norvegicus(Norway rat) |
Genome |
mRNA | Protein | Name |
---|---|---|
NM_001271541.1 | NP_001258470.1 | serine/threonine/tyrosine-interacting protein |
Pan troglodytes (chimpanzee) | STYX | XP_001159524.1 |
Canis lupus familiaris (dog) | STYX | XP_005623462.1 |
Homo sapiens (human) | STYX | NP_660294.1 |
STYX | XP_001082157.1 | |
Rattus norvegicus (Norway rat) | Styx | NP_001258470.1 |
Danio rerio (zebrafish) | styx | NP_001019561.1 |
Xenopus tropicalis (tropical clawed frog) | styx | NP_001135695.1 |
Bos taurus (cattle) | STYX | NP_001180057.1 |
Mus musculus (house mouse) | Styx | NP_062611.2 |
Gallus gallus (chicken) | STYX | XP_421475.3 |
The pseudophosphatase STYX targets the F-box of FBXW7 and inhibits SCFFBXW7 function.
Reiterer V, Figueras-Puig C, Le Guerroue F, Confalonieri S, Vecchi M, Jalapothu D, Kanse SM, Deshaies RJ, Di Fiore PP, Behrends C, Farhan H
The EMBO journal36(3)260-273(2017 Feb)
Pseudophosphatase STYX modulates cell-fate decisions and cell migration by spatiotemporal regulation of ERK1/2.
Reiterer V, Fey D, Kolch W, Kholodenko BN, Farhan H
Proceedings of the National Academy of Sciences of the United States of America110(31)E2934-43(2013 Jul)
The archetype STYX/dead-phosphatase complexes with a spermatid mRNA-binding protein and is essential for normal sperm production.
Wishart MJ, Dixon JE
Proceedings of the National Academy of Sciences of the United States of America99(4)2112-7(2002 Feb)
GeneRIFs: Gene References Into Functions What's a GeneRIF?
results identify STYX as an important regulator of ERK1/2 signaling critical for cell migration
Title: Pseudophosphatase STYX modulates cell-fate decisions and cell migration by spatiotemporal regulation of ERK1/2.
The following Styx gene cDNA ORF clone sequences were retrieved from the NCBI Reference Sequence Database (RefSeq). These sequences represent the protein coding region of the Styx cDNA ORF which is encoded by the open reading frame (ORF) sequence. ORF sequences can be delivered in our standard vector, pcDNA3.1+/C-(K)DYK or the vector of your choice as an expression/transfection-ready ORF clone. Not the clone you want? Click here to find your clone.
CloneID | ORa11290 | |
Clone ID Related Accession (Same CDS sequence) | NM_001271541.1 | |
Accession Version | NM_001271541.1 Latest version! | Documents for ORF clone product in default vector |
Sequence Information | ORF Nucleotide Sequence (Length: 672bp) Protein sequence SNP |
|
Vector | pcDNA3.1-C-(k)DYK or customized vector | User Manual |
Clone information | Clone Map | MSDS |
Tag on pcDNA3.1+/C-(K)DYK | C terminal DYKDDDDK tags | |
ORF Insert Method | CloneEZ™ Seamless cloning technology | |
Insert Structure | linear | |
Update Date | 2019-04-18 | |
Organism | Rattus norvegicus(Norway rat) | |
Product | serine/threonine/tyrosine-interacting protein | |
Comment | Comment: PROVISIONAL REFSEQ: This record has not yet been subject to final NCBI review. The reference sequence was derived from AABR07017254.1. On or before Oct 14, 2012 this sequence version replaced XM_003751450.1, XM_003752789.1. Sequence Note: The RefSeq transcript and protein were derived from genomic sequence to make the sequence consistent with the reference genome assembly. The genomic coordinates used for the transcript record were based on alignments to rat ESTs BF408902.1 and FQ204490.1 and to mouse NM_019637.3. ##Evidence-Data-START## RNAseq introns :: single sample supports all introns SAMD00052296, SAMD00052297 [ECO:0000348] ##Evidence-Data-END## |
1 | ATGGAGGACG TGAAACTGGA GTTCCCCTCG CTCCCGCAGT GCAAAGACGA CGCCGAGGAG |
The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.
RefSeq | NP_001258470.1 |
CDS | 209..880 |
Translation |
Target ORF information:
Target ORF information:
|
NM_001271541.1 |
1 | ATGGAGGACG TGAAACTGGA GTTCCCCTCG CTCCCGCAGT GCAAAGACGA CGCCGAGGAG |
The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.
The pseudophosphatase STYX targets the F-box of FBXW7 and inhibits SCFFBXW7 function. |
Pseudophosphatase STYX modulates cell-fate decisions and cell migration by spatiotemporal regulation of ERK1/2. |
The archetype STYX/dead-phosphatase complexes with a spermatid mRNA-binding protein and is essential for normal sperm production. |