Gene Symbol | Chia |
Entrez Gene ID | 113901 |
Full Name | chitinase, acidic |
General protein information |
|
Gene Type | protein-coding |
Organism | Rattus norvegicus(Norway rat) |
Genome |
ORF » Species Summary » Rattus norvegicus » Chia cDNA ORF clone
gRNAs
Gene Symbol | Chia |
Entrez Gene ID | 113901 |
Full Name | chitinase, acidic |
General protein information |
|
Gene Type | protein-coding |
Organism | Rattus norvegicus(Norway rat) |
Genome |
mRNA | Protein | Name |
---|---|---|
NM_207586.2 | NP_997469.1 | acidic mammalian chitinase precursor |
Danio rerio (zebrafish) | zgc:65788 | NP_955897.2 |
Danio rerio (zebrafish) | chia.4 | NP_956740.1 |
Magnaporthe oryzae (rice blast fungus) | MGG_01247 | XP_003714154.1 |
Bos taurus (cattle) | CHIA | NP_777124.1 |
Gallus gallus (chicken) | CHIA | NP_989760.1 |
Danio rerio (zebrafish) | chia.3 | NP_998378.1 |
Homo sapiens (human) | CHIA | NP_970615.2 |
Xenopus tropicalis (tropical clawed frog) | chia | NP_001186489.1 |
CHIA | XP_001104487.1 | |
Canis lupus familiaris (dog) | CHIA | XP_537030.3 |
Mus musculus (house mouse) | Chia1 | NP_075675.2 |
Rattus norvegicus (Norway rat) | Chia | NP_997469.1 |
Danio rerio (zebrafish) | zgc:173927 | NP_001103511.1 |
Neurospora crassa | NCU03209 | XP_965309.2 |
Evidence supporting a role for mammalian chitinases in efficacy of caspofungin against experimental aspergillosis in immunocompromised rats.
Verwer PE, ten Kate MT, Falcone FH, Morroll S, Verbrugh HA, Bakker-Woudenberg IA, van de Sande WW
PloS one8(10)e75848(2013)
Increased expression of acidic mammalian chitinase and chitotriosidase in the nasal mucosa of patients with allergic rhinitis.
Cho WS, Kim TH, Lee HM, Lee SH, Lee SH, Yoo JH, Kim YS, Lee SH
The Laryngoscope120(5)870-5(2010 May)
Polymorphisms of chitinases are not associated with asthma.
Wu AC, Lasky-Su J, Rogers CA, Klanderman BJ, Litonjua A
The Journal of allergy and clinical immunology125(3)754-7, 757.e1-757.e2(2010 Mar)
Inhibition of acidic mammalian chitinase by RNA interference suppresses ovalbumin-sensitized allergic asthma.
Yang CJ, Liu YK, Liu CL, Shen CN, Kuo ML, Su CC, Tseng CP, Yen TC, Shen CR
Human gene therapy20(12)1597-606(2009 Dec)
Differential enzymatic activity of common haplotypic versions of the human acidic Mammalian chitinase protein.
Seibold MA, Reese TA, Choudhry S, Salam MT, Beckman K, Eng C, Atakilit A, Meade K, Lenoir M, Watson HG, Thyne S, Kumar R, Weiss KB, Grammer LC, Avila P, Schleimer RP, Fahy JV, Rodriguez-Santana J, Rodriguez-Cintron W, Boot RG, Sheppard D, Gilliland FD, Locksley RM, Burchard EG
The Journal of biological chemistry284(29)19650-8(2009 Jul)
GeneRIFs: Gene References Into Functions What's a GeneRIF?
Invasive pulmonary aspergillosis in immunocompromised rats caused a dramatic increase in chitinase activity.
Title: Evidence supporting a role for mammalian chitinases in efficacy of caspofungin against experimental aspergillosis in immunocompromised rats.
Report of cDNA that encodes a protein with a characteristic N-terminal 21 amino acid endoplasmic reticulum signal peptide; the putative protein is highly homologous to acidic mammalian chitinase (AMCase) precursor of mouse and human.
Title: Cloning of a rat lung fibrogenic factor.
The following Chia gene cDNA ORF clone sequences were retrieved from the NCBI Reference Sequence Database (RefSeq). These sequences represent the protein coding region of the Chia cDNA ORF which is encoded by the open reading frame (ORF) sequence. ORF sequences can be delivered in our standard vector, pcDNA3.1+/C-(K)DYK or the vector of your choice as an expression/transfection-ready ORF clone. Not the clone you want? Click here to find your clone.
CloneID | ORa42850 | |
Clone ID Related Accession (Same CDS sequence) | NM_207586.2 | |
Accession Version | NM_207586.2 Latest version! | Documents for ORF clone product in default vector |
Sequence Information | ORF Nucleotide Sequence (Length: 1422bp) Protein sequence SNP |
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Vector | pcDNA3.1-C-(k)DYK or customized vector | ![]() |
Clone information | Clone Map | ![]() |
Tag on pcDNA3.1+/C-(K)DYK | C terminal DYKDDDDK tags | |
ORF Insert Method | CloneEZ™ Seamless cloning technology | |
Insert Structure | linear | |
Update Date | 2019-12-24 | |
Organism | Rattus norvegicus(Norway rat) | |
Product | acidic mammalian chitinase precursor | |
Comment | Comment: PROVISIONAL REFSEQ: This record has not yet been subject to final NCBI review. The reference sequence was derived from AY486074.1. On Aug 30, 2012 this sequence version replaced NM_207586.1. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Gene record to access additional publications. ##Evidence-Data-START## Transcript exon combination :: AY486074.1 [ECO:0000332] RNAseq introns :: single sample supports all introns SAMEA2689599, SAMN02642715 [ECO:0000348] ##Evidence-Data-END## |
1 | ATGGCCAAGC TCATTCTTGT CACAGGTCTG GTTCTTCTGC TGAATGTTCA GCTGGGGTCT |
The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.
RefSeq | NP_997469.1 |
CDS | 24..1445 |
Translation |
Target ORF information:
Target ORF information:
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1 | ATGGCCAAGC TCATTCTTGT CACAGGTCTG GTTCTTCTGC TGAATGTTCA GCTGGGGTCT |
The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.
Evidence supporting a role for mammalian chitinases in efficacy of caspofungin against experimental aspergillosis in immunocompromised rats. |
Increased expression of acidic mammalian chitinase and chitotriosidase in the nasal mucosa of patients with allergic rhinitis. |
Polymorphisms of chitinases are not associated with asthma. |
Inhibition of acidic mammalian chitinase by RNA interference suppresses ovalbumin-sensitized allergic asthma. |
Differential enzymatic activity of common haplotypic versions of the human acidic Mammalian chitinase protein. |