Fbp2 cDNA ORF clone, Rattus norvegicus(Norway rat)
Gene Symbol | Fbp2 |
Entrez Gene ID | 114508 |
Full Name | fructose-bisphosphatase 2 |
Synonyms | FBPase |
General protein information |
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Gene Type | protein-coding |
Organism | Rattus norvegicus(Norway rat) |
Genome | |
Summary | last key-enzyme before the synthesis of glucose-6-phosphate of the gluconeogenic pathway [RGD, Feb 2006]. |
mRNA and Protein(s)
mRNA | Protein | Name |
---|---|---|
NM_053716.1 | NP_446168.1 | fructose-1,6-bisphosphatase isozyme 2 |

Canis lupus familiaris (dog) | FBP2 | XP_533504.2 |
Mus musculus (house mouse) | Fbp2 | NP_032020.2 |
Drosophila melanogaster (fruit fly) | fbp | NP_724223.2 |
Anopheles gambiae (African malaria mosquito) | AgaP_AGAP009173 | XP_319937.4 |
Arabidopsis thaliana (thale cress) | AT1G43670 | NP_175032.1 |
Pan troglodytes (chimpanzee) | FBP2 | XP_520718.2 |
Danio rerio (zebrafish) | fbp2 | NP_001004008.1 |
Bos taurus (cattle) | FBP2 | NP_001039629.1 |
Homo sapiens (human) | FBP2 | NP_003828.2 |
Rattus norvegicus (Norway rat) | Fbp2 | NP_446168.1 |
FBP2 | XP_002800246.1 | |
Gallus gallus (chicken) | FBP2 | XP_425039.1 |
Caenorhabditis elegans (roundworm) | fbp-1 | NP_491004.1 |
Oryza sativa (rice) | Os01g0866400 | NP_001044906.1 |
Xenopus tropicalis (tropical clawed frog) | fbp2 | NP_001027516.1 |

Related articles in PubMed
Nuclear accumulation of fructose 1,6-bisphosphatase is impaired in diabetic rat liver.
Bertinat R, Pontigo JP, P?rez M, Concha II, San Mart?n R, Guinovart JJ, Slebe JC, Y??ez AJ
Journal of cellular biochemistry113(3)848-56(2012 Mar)
Large-scale proteomics and phosphoproteomics of urinary exosomes.
Gonzales PA, Pisitkun T, Hoffert JD, Tchapyjnikov D, Star RA, Kleta R, Wang NS, Knepper MA
Journal of the American Society of Nephrology : JASN20(2)363-79(2009 Feb)
Calcium inhibits muscle FBPase and affects its intracellular localization in cardiomyocytes.
Gizak A, Majkowski M, Dus D, Dzugaj A
FEBS letters576(3)445-8(2004 Oct)
Mechanism of fat-induced hepatic gluconeogenesis: effect of metformin.
Song S, Andrikopoulos S, Filippis C, Thorburn AW, Khan D, Proietto J
American journal of physiology. Endocrinology and metabolism281(2)E275-82(2001 Aug)
GeneRIFs: Gene References Into Functions What's a GeneRIF?
Insulin and not hyperglycemia plays a crucial role in the nuclear accumulation of FBPase in vivo.
Title: Nuclear accumulation of fructose 1,6-bisphosphatase is impaired in diabetic rat liver.
Ca2+ appears to be a strong inhibitor of muscle FBPase
Title: Calcium inhibits muscle FBPase and affects its intracellular localization in cardiomyocytes.
The following Fbp2 gene cDNA ORF clone sequences were retrieved from the NCBI Reference Sequence Database (RefSeq). These sequences represent the protein coding region of the Fbp2 cDNA ORF which is encoded by the open reading frame (ORF) sequence. ORF sequences can be delivered in our standard vector, pcDNA3.1+/C-(K)DYK or the vector of your choice as an expression/transfection-ready ORF clone. Not the clone you want? Click here to find your clone.
CloneID | ORa10399 | |
Clone ID Related Accession (Same CDS sequence) | NM_053716.1 | |
Accession Version | NM_053716.1 Latest version! | Documents for ORF clone product in default vector |
Sequence Information | ORF Nucleotide Sequence (Length: 1020bp) Protein sequence SNP |
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Vector | pcDNA3.1+/C-(K)DYK or customized vector | ![]() |
Clone information | Clone Map | ![]() |
Tag on pcDNA3.1+/C-(K)DYK | C terminal DYKDDDDK tags | |
ORF Insert Method | CloneEZ™ Seamless cloning technology | |
Insert Structure | linear | |
Update Date | 2019-09-02 | |
Organism | Rattus norvegicus(Norway rat) | |
Product | fructose-1,6-bisphosphatase isozyme 2 | |
Comment | Comment: PROVISIONAL REFSEQ: This record has not yet been subject to final NCBI review. The reference sequence was derived from AJ005046.1. ##Evidence-Data-START## Transcript exon combination :: AJ005046.1 [ECO:0000332] RNAseq introns :: single sample supports all introns SAMEA2689597, SAMEA2689599 [ECO:0000348] ##Evidence-Data-END## |
1 | ATGACGGACA GAAGCCCCTT TGAGACAGAC ATGCTGACCC TGACCCGTTA CGTTATGGAA |
The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.
RefSeq | NP_446168.1 |
CDS | 59..1078 |
Translation |

Target ORF information:
Target ORF information:
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ORF Insert Sequence:
1 | ATGACGGACA GAAGCCCCTT TGAGACAGAC ATGCTGACCC TGACCCGTTA CGTTATGGAA |
The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.
![]() |
Nuclear accumulation of fructose 1,6-bisphosphatase is impaired in diabetic rat liver. |
![]() |
Large-scale proteomics and phosphoproteomics of urinary exosomes. |
![]() |
Calcium inhibits muscle FBPase and affects its intracellular localization in cardiomyocytes. |
![]() |
Mechanism of fat-induced hepatic gluconeogenesis: effect of metformin. |