ORF cDNA Clones and Custom Clones » Species Summary » Rattus norvegicus » Fbp2 cDNA ORF clone

Fbp2 cDNA ORF clone, Rattus norvegicus(Norway rat)

Collapse all
Expand all

Summary

Gene Symbol	Fbp2
Entrez Gene ID	114508
Full Name	fructose-bisphosphatase 2
Synonyms	FBPase
General protein information	Preferred Names fructose-bisphosphatase 2 Names fructose-1,6-bisphosphatase isozyme 2 D-fructose-1,6-bisphosphate 1-phosphohydrolase 2 FBPase 2 fructose-1,6-bisphosphatase 2 muscle FBPase
Gene Type	protein-coding
Organism	Rattus norvegicus(Norway rat)
Genome	Chromosome: 17 Map Location: 17p14
Summary	last key-enzyme before the synthesis of glucose-6-phosphate of the gluconeogenic pathway [RGD, Feb 2006].

Reference Sequences (RefSeq)

mRNA and Protein(s)

mRNA	Protein	Name
NM_053716.1	NP_446168.1	fructose-1,6-bisphosphatase isozyme 2

Homologies

Canis lupus familiaris (dog)	FBP2	XP_533504.2
Mus musculus (house mouse)	Fbp2	NP_032020.2
Drosophila melanogaster (fruit fly)	fbp	NP_724223.2
Anopheles gambiae (African malaria mosquito)	AgaP_AGAP009173	XP_319937.4
Arabidopsis thaliana (thale cress)	AT1G43670	NP_175032.1
Pan troglodytes (chimpanzee)	FBP2	XP_520718.2
Danio rerio (zebrafish)	fbp2	NP_001004008.1
Bos taurus (cattle)	FBP2	NP_001039629.1
Homo sapiens (human)	FBP2	NP_003828.2
Rattus norvegicus (Norway rat)	Fbp2	NP_446168.1
	FBP2	XP_002800246.1
Gallus gallus (chicken)	FBP2	XP_425039.1
Caenorhabditis elegans (roundworm)	fbp-1	NP_491004.1
Oryza sativa (rice)	Os01g0866400	NP_001044906.1
Xenopus tropicalis (tropical clawed frog)	fbp2	NP_001027516.1

Bibliography

Related articles in PubMed

Nuclear accumulation of fructose 1,6-bisphosphatase is impaired in diabetic rat liver.
Bertinat R, Pontigo JP, P?rez M, Concha II, San Mart?n R, Guinovart JJ, Slebe JC, Y??ez AJ
Journal of cellular biochemistry113(3)848-56(2012 Mar)

Large-scale proteomics and phosphoproteomics of urinary exosomes.
Gonzales PA, Pisitkun T, Hoffert JD, Tchapyjnikov D, Star RA, Kleta R, Wang NS, Knepper MA
Journal of the American Society of Nephrology : JASN20(2)363-79(2009 Feb)

Calcium inhibits muscle FBPase and affects its intracellular localization in cardiomyocytes.
Gizak A, Majkowski M, Dus D, Dzugaj A
FEBS letters576(3)445-8(2004 Oct)

Mechanism of fat-induced hepatic gluconeogenesis: effect of metformin.
Song S, Andrikopoulos S, Filippis C, Thorburn AW, Khan D, Proietto J
American journal of physiology. Endocrinology and metabolism281(2)E275-82(2001 Aug)

GeneRIFs: Gene References Into Functions What's a GeneRIF?

Insulin and not hyperglycemia plays a crucial role in the nuclear accumulation of FBPase in vivo.
Title: Nuclear accumulation of fructose 1,6-bisphosphatase is impaired in diabetic rat liver.

Ca2+ appears to be a strong inhibitor of muscle FBPase
Title: Calcium inhibits muscle FBPase and affects its intracellular localization in cardiomyocytes.

Collapse all
Expand all

The following Fbp2 gene cDNA ORF clone sequences were retrieved from the NCBI Reference Sequence Database (RefSeq). These sequences represent the protein coding region of the Fbp2 cDNA ORF which is encoded by the open reading frame (ORF) sequence. ORF sequences can be delivered in our standard vector, pcDNA3.1⁺/C-(K)DYK or the vector of your choice as an expression/transfection-ready ORF clone. Not the clone you want? Click here to find your clone.

Collapse all
Expand all

***CloneID	Accession No.	Definition	**Vector	*Turnaround time	Price (USD)	Select
ORa10399	NM_053716.1 Latest version!	Rattus norvegicus fructose-bisphosphatase 2 (Fbp2), mRNA.	pcDNA3.1-C-(k)DYK or customized vector	7-9	$188.30 $269.00

ORF Online Only Promotion

Next-day Shipping ORF Clones ( in default vector with tag)
1 Clone	30% OFF
2-4 Clone	40% OFF
5 or more Clone	50% OFF
All Other ORF Clones
30% OFF

*Business Day

** You may select a custom vector to replace pcDNA3.1+/C-(K)DYK after clone is added to cart.

** GenScript guarantees 100% sequence accuracy of all synthetic DNA constructs we deliver, but we do not guarantee protein expression in your experimental system. Protein expression is influenced by many factors that may vary between experiments or laboratories. In addition, please pay attention to the signal peptide, propeptide and transit peptide in target ORF, which may affect the choice of vector (N/C terminal tag vector).

***One clone ID might be correlated to multiple accession numbers, which share the same CDS sequence.

Reference Sequences (Refseq)

Fbp2 ( NM_053716.1 ) cDNA ORF clone, Rattus norvegicus(Norway rat) -> NP_446168.1 Rattus norvegicus fructose-bisphosphatase 2 (Fbp2), mRNA.

Price & Availability↑

CloneID	ORa10399
Clone ID Related Accession (Same CDS sequence)	NM_053716.1
Accession Version	NM_053716.1 Latest version!	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 1020bp) Protein sequence SNP
Vector	pcDNA3.1⁺/C-(K)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2019-09-02
Organism	Rattus norvegicus(Norway rat)
Product	fructose-1,6-bisphosphatase isozyme 2
Comment	Comment: PROVISIONAL REFSEQ: This record has not yet been subject to final NCBI review. The reference sequence was derived from AJ005046.1. ##Evidence-Data-START## Transcript exon combination :: AJ005046.1 [ECO:0000332] RNAseq introns :: single sample supports all introns SAMEA2689597, SAMEA2689599 [ECO:0000348] ##Evidence-Data-END##

ATGACGGACA GAAGCCCCTT TGAGACAGAC ATGCTGACCC TGACCCGTTA CGTTATGGAA 
AAGGGGCGAC AGGCCAAAGG GACCGGAGAA CTCACCCAGC TGCTCAACTC GATGCTGACT 
GCCATCAAAG CCATCTCTTC CGCTGTGCGA AAGGCCGGCC TGGCCAACCT GTATGGGATT 
GCGGGAAGCG TGAATGTGAC AGGGGATGAG GTGAAGAAAC TGGATGTGCT GTCCAATTCC 
CTGGTGATCA ACATGCTTCA GTCCTCCTAC AGCACCTGTG TGCTTGTCTC AGAAGAGAAT 
AAAGAGGCTG TGATCACAGC CAAGGAGAGG AGGGGGAAAT ATGTGGTTTG CTTTGACCCA 
CTGGATGGAT CTTCAAACAT TGACTGCCTG GCTTCCATTG GAACTATATT TGCTATCTAC 
AGAAAGACCA CAGAGGATGA GCCTTCCGAG AAGGATGCCT TGCAGCCTGG ACGCAATATC 
GTGGCTGCAG GTTATGCACT GTATGGTAGT GCAACCCTGG TGGCTCTTTC TACAGGGCAA 
GGAGTGGATC TCTTCATGCT GGACCCGGCT CTTGGAGAAT TCGTGCTAGT GGAAAAAGAT 
ATCCGGATTA AGAAGAAAGG GAAAATTTTT AGCCTCAATG AGGGCTATGC CAAGTATTTT 
GATGCTGCTA CCGCTGAGTA TGTACAGAAA AAGAAGTTCC CTGAGGATGG CAGTGCACCT 
TACGGGGCAA GGTACGTGGG TTCCATGGTG GCTGATGTGC ATCGCACCCT GGTCTATGGA 
GGAATCTTCA TGTACCCAGC CAACCAGAAG AGTCCTAATG GCAAGCTCCG GCTCCTGTAT 
GAATGCAATC CTGTAGCCTA TATCATTGAG CAGGCAGGAG GCATGGCAAC CACAGGCACC 
CAGCCGGTAC TGGATGTAAA GCCTGAGAGC ATTCACCAGC GAGTCCCCCT CATTCTGGGG 
TCCCCGGAAG ATGTGCAAGA ATATCTCAGC TGTGTGCAAA GAAACCAGGC AGGCAGGTAG

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	NP_446168.1
CDS	59..1078
Translation	MTDRSPFETDMLTLTRYVMEKGRQAKGTGELTQLLNSMLTAIKAISSAVRKAGLANLYGIAGSVNVTGDEVKKLDVLSNSLVINMLQSSYSTCVLVSEENKEAVITAKERRGKYVVCFDPLDGSSNIDCLASIGTIFAIYRKTTEDEPSEKDALQPGRNIVAAGYALYGSATLVALSTGQGVDLFMLDPALGEFVLVEKDIRIKKKGKIFSLNEGYAKYFDAATAEYVQKKKFPEDGSAPYGARYVGSMVADVHRTLVYGGIFMYPANQKSPNGKLRLLYECNPVAYIIEQAGGMATTGTQPVLDVKPESIHQRVPLILGSPEDVQEYLSCVQRNQAGR

Target ORF information:

RefSeq Version	NM_053716.1
Organism	Rattus norvegicus(Norway rat)
Definition	Rattus norvegicus fructose-bisphosphatase 2 (Fbp2), mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

NM_053716.1

ORF Insert Sequence:

ATGACGGACA GAAGCCCCTT TGAGACAGAC ATGCTGACCC TGACCCGTTA CGTTATGGAA 
AAGGGGCGAC AGGCCAAAGG GACCGGAGAA CTCACCCAGC TGCTCAACTC GATGCTGACT 
GCCATCAAAG CCATCTCTTC CGCTGTGCGA AAGGCCGGCC TGGCCAACCT GTATGGGATT 
GCGGGAAGCG TGAATGTGAC AGGGGATGAG GTGAAGAAAC TGGATGTGCT GTCCAATTCC 
CTGGTGATCA ACATGCTTCA GTCCTCCTAC AGCACCTGTG TGCTTGTCTC AGAAGAGAAT 
AAAGAGGCTG TGATCACAGC CAAGGAGAGG AGGGGGAAAT ATGTGGTTTG CTTTGACCCA 
CTGGATGGAT CTTCAAACAT TGACTGCCTG GCTTCCATTG GAACTATATT TGCTATCTAC 
AGAAAGACCA CAGAGGATGA GCCTTCCGAG AAGGATGCCT TGCAGCCTGG ACGCAATATC 
GTGGCTGCAG GTTATGCACT GTATGGTAGT GCAACCCTGG TGGCTCTTTC TACAGGGCAA 
GGAGTGGATC TCTTCATGCT GGACCCGGCT CTTGGAGAAT TCGTGCTAGT GGAAAAAGAT 
ATCCGGATTA AGAAGAAAGG GAAAATTTTT AGCCTCAATG AGGGCTATGC CAAGTATTTT 
GATGCTGCTA CCGCTGAGTA TGTACAGAAA AAGAAGTTCC CTGAGGATGG CAGTGCACCT 
TACGGGGCAA GGTACGTGGG TTCCATGGTG GCTGATGTGC ATCGCACCCT GGTCTATGGA 
GGAATCTTCA TGTACCCAGC CAACCAGAAG AGTCCTAATG GCAAGCTCCG GCTCCTGTAT 
GAATGCAATC CTGTAGCCTA TATCATTGAG CAGGCAGGAG GCATGGCAAC CACAGGCACC 
CAGCCGGTAC TGGATGTAAA GCCTGAGAGC ATTCACCAGC GAGTCCCCCT CATTCTGGGG 
TCCCCGGAAG ATGTGCAAGA ATATCTCAGC TGTGTGCAAA GAAACCAGGC AGGCAGGTAG

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

PubMed

Nuclear accumulation of fructose 1,6-bisphosphatase is impaired in diabetic rat liver.
Journal of cellular biochemistry113(3)848-56(2012 Mar)
Bertinat R,Pontigo JP,P?rez M,Concha II,San Mart?n R,Guinovart JJ,Slebe JC,Y??ez AJ

Large-scale proteomics and phosphoproteomics of urinary exosomes.
Journal of the American Society of Nephrology : JASN20(2)363-79(2009 Feb)
Gonzales PA,Pisitkun T,Hoffert JD,Tchapyjnikov D,Star RA,Kleta R,Wang NS,Knepper MA

Calcium inhibits muscle FBPase and affects its intracellular localization in cardiomyocytes.
FEBS letters576(3)445-8(2004 Oct)
Gizak A,Majkowski M,Dus D,Dzugaj A

Mechanism of fat-induced hepatic gluconeogenesis: effect of metformin.
American journal of physiology. Endocrinology and metabolism281(2)E275-82(2001 Aug)
Song S,Andrikopoulos S,Filippis C,Thorburn AW,Khan D,Proietto J

Collapse all
Expand all

Fbp2 cDNA ORF clone, Rattus norvegicus(Norway rat)

Summary

Reference Sequences (RefSeq)

Pathways from BioSystems

Homologies

Gene Ontology

Bibliography

Reference Sequences (Refseq)

Target ORF information:

Target ORF information:

ORF Insert Sequence:

PubMed

Resources

Support

Company

Shopping Tools