Mapk8ip1 cDNA ORF clone, Rattus norvegicus(Norway rat)
| Gene Symbol | Mapk8ip1 |
| Entrez Gene ID | 116457 |
| Full Name | mitogen-activated protein kinase 8 interacting protein 1 |
| Synonyms | JIP1,Jip-1,Mapk8ip |
| General protein information |
|
| Gene Type | protein-coding |
| Organism | Rattus norvegicus(Norway rat) |
| Genome | |
| Summary | may play a role in the SAPK mediated stress-induced cellular responses [RGD, Feb 2006]. |
mRNA and Protein(s)
| mRNA | Protein | Name |
|---|---|---|
| NM_053777.1 | NP_446229.1 | C-Jun-amino-terminal kinase-interacting protein 1 |
| Homo sapiens (human) | MAPK8IP1 | NP_005447.1 |
| Canis lupus familiaris (dog) | MAPK8IP1 | XP_005631786.1 |
| Rattus norvegicus (Norway rat) | Mapk8ip1 | NP_446229.1 |
| Gallus gallus (chicken) | MAPK8IP1 | XP_421126.4 |
| MAPK8IP1 | XP_001113132.1 | |
| Danio rerio (zebrafish) | LOC100333948 | XP_005172441.1 |
| Bos taurus (cattle) | MAPK8IP1 | NP_001095978.1 |
| Pan troglodytes (chimpanzee) | MAPK8IP1 | XP_001160866.1 |
| Mus musculus (house mouse) | Mapk8ip1 | NP_035292.2 |
| Xenopus tropicalis (tropical clawed frog) | mapk8ip1 | XP_002934139.2 |
Related articles in PubMed
Class I HDACs control a JIP1-dependent pathway for kinesin-microtubule binding in cardiomyocytes.
Blakeslee WW, Lin YH, Stratton MS, Tatman PD, Hu T, Ferguson BS, McKinsey TA
Journal of molecular and cellular cardiology11274-82(2017 Nov)
Islet Brain 1 Protects Insulin Producing Cells against Lipotoxicity.
Brajkovic S, Ferdaoussi M, Pawlowski V, Ezanno H, Plaisance V, Zmuda E, Hai T, Annicotte JS, Waeber G, Abderrahmani A
Journal of diabetes research20169158562(2016)
JIP1 mediates anterograde transport of Rab10 cargos during neuronal polarization.
Deng CY, Lei WL, Xu XH, Ju XC, Liu Y, Luo ZG
The Journal of neuroscience : the official journal of the Society for Neuroscience34(5)1710-23(2014 Jan)
The POSH/JIP-1 scaffold network regulates TCR-mediated JNK1 signals and effector function in CD8(+) T cells.
Cunningham CA, Knudson KM, Peng BJ, Teixeiro E, Daniels MA
European journal of immunology43(12)3361-71(2013 Dec)
Loss of c-Jun N-terminal kinase-interacting protein-1 does not affect axonal transport of the amyloid precursor protein or Aβ production.
Vagnoni A, Glennon EB, Perkinton MS, Gray EH, Noble W, Miller CC
Human molecular genetics22(22)4646-52(2013 Nov)
GeneRIFs: Gene References Into Functions What's a GeneRIF?
Suppression of IB1 level mimicked the harmful effects of palmitate on the beta cell survival and GSIS. Conversely, ectopic expression of IB1 counteracted the deleterious effects of palmitate on the beta cell survival and insulin secretion
Title: Islet Brain 1 Protects Insulin Producing Cells against Lipotoxicity.
this study demonistrated that JIP1 mediates anterograde transport of Rab10 cargos during neuronal polarization
Title: JIP1 mediates anterograde transport of Rab10 cargos during neuronal polarization.
study found levels of JIP1 are not altered in Alzheimer's disease brains
Title: Loss of c-Jun N-terminal kinase-interacting protein-1 does not affect axonal transport of the amyloid precursor protein or Aβ production.
SOCS3 binds to the carboxyl terminus of C-Jun N-terminal kinase-interacting protein-1 (JIP1), increases its serine phosphorylation, and increases its binding to kinesin.
Title: Two cytokine signaling molecules co-operate to promote axonal transport and growth.
JIP1 and JIP3 play important roles in the activation of JNK during simulated ischemia-reperfusion challenge in H9c2 cells.
Title: Regulation of stress-associated scaffold proteins JIP1 and JIP3 on the c-Jun NH2-terminal kinase in ischemia-reperfusion.
The following Mapk8ip1 gene cDNA ORF clone sequences were retrieved from the NCBI Reference Sequence Database (RefSeq). These sequences represent the protein coding region of the Mapk8ip1 cDNA ORF which is encoded by the open reading frame (ORF) sequence. ORF sequences can be delivered in our standard vector, pcDNA3.1+/C-(K)DYK or the vector of your choice as an expression/transfection-ready ORF clone. Not the clone you want? Click here to find your clone.
| CloneID | ORa12669 | |
| Clone ID Related Accession (Same CDS sequence) | NM_053777.1 | |
| Accession Version | NM_053777.1 Latest version! | Documents for ORF clone product in default vector |
| Sequence Information | ORF Nucleotide Sequence (Length: 2100bp) Protein sequence SNP |
|
| Vector | pcDNA3.1-C-(k)DYK or customized vector |  User Manual |
| Clone information | Clone Map | MSDS |
| Tag on pcDNA3.1+/C-(K)DYK | C terminal DYKDDDDK tags | |
| ORF Insert Method | CloneEZ™ Seamless cloning technology | |
| Insert Structure | linear | |
| Update Date | 2019-09-20 | |
| Organism | Rattus norvegicus(Norway rat) | |
| Product | C-Jun-amino-terminal kinase-interacting protein 1 | |
| Comment | Comment: PROVISIONAL REFSEQ: This record has not yet been subject to final NCBI review. The reference sequence was derived from AF109774.1. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Gene record to access additional publications. ##Evidence-Data-START## Transcript exon combination :: AF109774.1 [ECO:0000332] RNAseq introns :: single sample supports all introns SAMD00052297 [ECO:0000348] ##Evidence-Data-END## | |
1 | ATGCAGCTGG TACTGAAGAT GGATTCGAGC CCAGACAATG ACAGCTGGTT GGAGGATCAG |
The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.
| RefSeq | NP_446229.1 |
| CDS | 218..2317 |
| Translation |
Target ORF information:
Target ORF information:
|
 NM_053777.1 |
ORF Insert Sequence:
1 | ATGCAGCTGG TACTGAAGAT GGATTCGAGC CCAGACAATG ACAGCTGGTT GGAGGATCAG |
The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.
 |
Class I HDACs control a JIP1-dependent pathway for kinesin-microtubule binding in cardiomyocytes. |
|
Islet Brain 1 Protects Insulin Producing Cells against Lipotoxicity. |
|
JIP1 mediates anterograde transport of Rab10 cargos during neuronal polarization. |
|
The POSH/JIP-1 scaffold network regulates TCR-mediated JNK1 signals and effector function in CD8(+) T cells. |
|
Loss of c-Jun N-terminal kinase-interacting protein-1 does not affect axonal transport of the amyloid precursor protein or Aβ production. |