ORF cDNA Clones and Custom Clones » Species Summary » Rattus norvegicus » Gsta1 cDNA ORF clone

Gsta1 cDNA ORF clone, Rattus norvegicus(Norway rat)

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Summary

Gene Symbol	Gsta1
Entrez Gene ID	24421
Full Name	glutathione S-transferase alpha 1
Synonyms	GST 2-2,GST A3-3,GST AA,GST Yc1,Gsta3,Gsta5,Yc1
General protein information	Preferred Names glutathione S-transferase alpha 1 Names glutathione S-transferase alpha-3 Glutathione-S-transferase alpha type (Ya) glutathione S-transferase A3 subunit glutathione S-transferase A5 glutathione S-transferase Yc1 subunit
Gene Type	protein-coding
Organism	Rattus norvegicus(Norway rat)
Genome	Chromosome: 9 Map Location: 9q13
Summary	may play a role in drug resistance and carcinogenesis [RGD, Feb 2006].

Reference Sequences (RefSeq)

mRNA and Protein(s)

mRNA	Protein	Name
NM_031509.2	NP_113697.1	glutathione S-transferase alpha-3

Homologies

Rattus norvegicus (Norway rat)	Gsta1	NP_113697.1
Gallus gallus (chicken)	LOC100859645	XP_003641074.1
Gallus gallus (chicken)	LOC395611	XP_004940536.1
Gallus gallus (chicken)	GSTA3	NP_001001777.1

Bibliography

Related articles in PubMed

Analysis of proteomic changes induced upon cellular differentiation of the human intestinal cell line Caco-2.
Buhrke T, Lengler I, Lampen A
Development, growth & differentiation53(3)411-26(2011 Apr)

GSTA1, GSTO1 and GSTO2 gene polymorphisms in Italian asthma patients.
Polimanti R, Piacentini S, Moscatelli B, Pellicciotti L, Manfellotto D, Fuciarelli M
Clinical and experimental pharmacology & physiology37(8)870-2(2010 Aug)

The role of a topologically conserved isoleucine in glutathione transferase structure, stability and function.
Achilonu I, Gildenhuys S, Fisher L, Burke J, Fanucchi S, Sewell BT, Fernandes M, Dirr HW
Acta crystallographica. Section F, Structural biology and crystallization communications66(Pt 7)776-80(2010 Jul)

Genetic polymorphisms and the efficacy and toxicity of cisplatin-based chemotherapy in ovarian cancer patients.
Khrunin AV, Moisseev A, Gorbunova V, Limborska S
The pharmacogenomics journal10(1)54-61(2010 Feb)

Isoenzyme-specific up-regulation of glutathione transferase and aldo-keto reductase mRNA expression by dietary quercetin in rat liver.
Odbayar TO, Kimura T, Tsushida T, Ide T
Molecular and cellular biochemistry325(1-2)121-30(2009 May)

GeneRIFs: Gene References Into Functions What's a GeneRIF?

a considerable amount of GSTs, in particular GSTA1-1, GSTA2-2, and GSTA3-3, corresponding to 10% of the cytosolic pool is electrostatically associated with the outer nuclear membrane, and a similar quantity is compartmentalized inside the nucleus
Title: Electrostatic association of glutathione transferase to the nuclear membrane. Evidence of an enzyme defense barrier at the nuclear envelope.

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The following Gsta1 gene cDNA ORF clone sequences were retrieved from the NCBI Reference Sequence Database (RefSeq). These sequences represent the protein coding region of the Gsta1 cDNA ORF which is encoded by the open reading frame (ORF) sequence. ORF sequences can be delivered in our standard vector, pcDNA3.1⁺/C-(K)DYK or the vector of your choice as an expression/transfection-ready ORF clone. Not the clone you want? Click here to find your clone.

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***CloneID	Accession No.	Definition	**Vector	*Turnaround time	Price (USD)	Select
ORa07945	NM_031509.2 Latest version!	Rattus norvegicus glutathione S-transferase alpha 1 (Gsta1), mRNA.	pcDNA3.1⁺/C-(K)DYK or customized vector	5-7	$139.30 $199.00

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** You may select a custom vector to replace pcDNA3.1+/C-(K)DYK after clone is added to cart.

** GenScript guarantees 100% sequence accuracy of all synthetic DNA constructs we deliver, but we do not guarantee protein expression in your experimental system. Protein expression is influenced by many factors that may vary between experiments or laboratories. In addition, please pay attention to the signal peptide, propeptide and transit peptide in target ORF, which may affect the choice of vector (N/C terminal tag vector).

***One clone ID might be correlated to multiple accession numbers, which share the same CDS sequence.

Reference Sequences (Refseq)

Gsta1 ( NM_031509.2 ) cDNA ORF clone, Rattus norvegicus(Norway rat) -> NP_113697.1 Rattus norvegicus glutathione S-transferase alpha 1 (Gsta1), mRNA.

Price & Availability↑

CloneID	ORa07945
Clone ID Related Accession (Same CDS sequence)	NM_031509.2
Accession Version	NM_031509.2 Latest version!	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 666bp) Protein sequence SNP
Vector	pcDNA3.1⁺/C-(K)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2019-12-25
Organism	Rattus norvegicus(Norway rat)
Product	glutathione S-transferase alpha-3
Comment	Comment: VALIDATED REFSEQ: This record has undergone validation or preliminary review. The reference sequence was derived from AF111160.1. On Jan 29, 2005 this sequence version replaced NM_031509.1. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Gene record to access additional publications. ##Evidence-Data-START## Transcript exon combination :: FQ213952.1, X78848.1 [ECO:0000332] RNAseq introns :: mixed/partial sample support SAMEA2689597, SAMEA2689598 [ECO:0000350] ##Evidence-Data-END## COMPLETENESS: full length.

ATGCCGGGGA AGCCAGTCCT TCACTACTTC GATGGCAGGG GGAGAATGGA GCCCATCCGG 
TGGCTCCTGG CTGCAGCTGG AGTAGAGTTT GAAGAACAAT TTCTGAAAAC TCGGGATGAC 
CTGGCCAGGC TAAGGAATGA TGGGAGTTTG ATGTTCCAGC AAGTGCCCAT GGTGGAGATT 
GATGGGATGA AGCTGGTGCA GACCAGAGCC ATTCTCAACT ACATTGCCAC CAAATACAAC 
CTCTATGGGA AGGACATGAA GGAGAGAGCC CTCATCGACA TGTATGCAGA AGGAGTGGCG 
GATCTGGATG AAATAGTTCT CCATTACCCT TACATTCCCC CTGGGGAGAA AGAGGCAAGT 
CTTGCCAAAA TCAAGGACAA AGCAAGGAAC CGTTACTTTC CTGCCTTTGA AAAGGTGTTG 
AAGAGCCATG GACAAGATTA TCTCGTTGGC AATAGGCTGA GCAGGGCTGA TGTTTACCTA 
GTTCAAGTTC TCTACCATGT GGAAGAGCTG GACCCCAGCG CTTTGGCCAA CTTCCCTCTG 
CTGAAGGCCC TGAGAACCAG AGTCAGCAAC CTCCCCACAG TGAAGAAGTT TCTTCAGCCT 
GGCAGCCAGA GGAAGCCATT AGAGGATGAG AAATGTGTAG AATCTGCAGT TAAGATCTTC 
AGTTAA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	NP_113697.1
CDS	240..905
Translation	MPGKPVLHYFDGRGRMEPIRWLLAAAGVEFEEQFLKTRDDLARLRNDGSLMFQQVPMVEIDGMKLVQTRAILNYIATKYNLYGKDMKERALIDMYAEGVADLDEIVLHYPYIPPGEKEASLAKIKDKARNRYFPAFEKVLKSHGQDYLVGNRLSRADVYLVQVLYHVEELDPSALANFPLLKALRTRVSNLPTVKKFLQPGSQRKPLEDEKCVESAVKIFS

Target ORF information:

RefSeq Version	NM_031509.2
Organism	Rattus norvegicus(Norway rat)
Definition	Rattus norvegicus glutathione S-transferase alpha 1 (Gsta1), mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

NM_031509.2

ORF Insert Sequence:

ATGCCGGGGA AGCCAGTCCT TCACTACTTC GATGGCAGGG GGAGAATGGA GCCCATCCGG 
TGGCTCCTGG CTGCAGCTGG AGTAGAGTTT GAAGAACAAT TTCTGAAAAC TCGGGATGAC 
CTGGCCAGGC TAAGGAATGA TGGGAGTTTG ATGTTCCAGC AAGTGCCCAT GGTGGAGATT 
GATGGGATGA AGCTGGTGCA GACCAGAGCC ATTCTCAACT ACATTGCCAC CAAATACAAC 
CTCTATGGGA AGGACATGAA GGAGAGAGCC CTCATCGACA TGTATGCAGA AGGAGTGGCG 
GATCTGGATG AAATAGTTCT CCATTACCCT TACATTCCCC CTGGGGAGAA AGAGGCAAGT 
CTTGCCAAAA TCAAGGACAA AGCAAGGAAC CGTTACTTTC CTGCCTTTGA AAAGGTGTTG 
AAGAGCCATG GACAAGATTA TCTCGTTGGC AATAGGCTGA GCAGGGCTGA TGTTTACCTA 
GTTCAAGTTC TCTACCATGT GGAAGAGCTG GACCCCAGCG CTTTGGCCAA CTTCCCTCTG 
CTGAAGGCCC TGAGAACCAG AGTCAGCAAC CTCCCCACAG TGAAGAAGTT TCTTCAGCCT 
GGCAGCCAGA GGAAGCCATT AGAGGATGAG AAATGTGTAG AATCTGCAGT TAAGATCTTC 
AGTTAA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

PubMed

Analysis of proteomic changes induced upon cellular differentiation of the human intestinal cell line Caco-2.
Development, growth & differentiation53(3)411-26(2011 Apr)
Buhrke T,Lengler I,Lampen A

GSTA1, GSTO1 and GSTO2 gene polymorphisms in Italian asthma patients.
Clinical and experimental pharmacology & physiology37(8)870-2(2010 Aug)
Polimanti R,Piacentini S,Moscatelli B,Pellicciotti L,Manfellotto D,Fuciarelli M

The role of a topologically conserved isoleucine in glutathione transferase structure, stability and function.
Acta crystallographica. Section F, Structural biology and crystallization communications66(Pt 7)776-80(2010 Jul)
Achilonu I,Gildenhuys S,Fisher L,Burke J,Fanucchi S,Sewell BT,Fernandes M,Dirr HW

Genetic polymorphisms and the efficacy and toxicity of cisplatin-based chemotherapy in ovarian cancer patients.
The pharmacogenomics journal10(1)54-61(2010 Feb)
Khrunin AV,Moisseev A,Gorbunova V,Limborska S

Isoenzyme-specific up-regulation of glutathione transferase and aldo-keto reductase mRNA expression by dietary quercetin in rat liver.
Molecular and cellular biochemistry325(1-2)121-30(2009 May)
Odbayar TO,Kimura T,Tsushida T,Ide T

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Gsta1 cDNA ORF clone, Rattus norvegicus(Norway rat)

Summary

Reference Sequences (RefSeq)

Pathways from BioSystems

Homologies

Gene Ontology

Bibliography

Reference Sequences (Refseq)

Target ORF information:

Target ORF information:

ORF Insert Sequence:

PubMed

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