S100a4 cDNA ORF clone, Rattus norvegicus(Norway rat)
| Gene Symbol | S100a4 |
| Entrez Gene ID | 24615 |
| Full Name | S100 calcium-binding protein A4 |
| Synonyms | 18A2,42A,CAPL,MTS1,P9ka,PEL98,RNP9KA |
| General protein information |
|
| Gene Type | protein-coding |
| Organism | Rattus norvegicus(Norway rat) |
| Genome | |
| Summary | may play a role in regulation of cell growth and differentiation [RGD, Feb 2006]. |
mRNA and Protein(s)
| mRNA | Protein | Name |
|---|---|---|
| NM_012618.2 | NP_036750.1 | protein S100-A4 |
| XM_006232592.3 | XP_006232654.1 | protein S100-A4 isoform X1 |
| Homo sapiens (human) | S100A4 | NP_002952.1 |
| S100A4 | XP_001110673.1 | |
| Danio rerio (zebrafish) | icn | NP_997926.1 |
| Danio rerio (zebrafish) | icn2 | NP_001076426.1 |
| Mus musculus (house mouse) | S100a4 | NP_035441.1 |
| Gallus gallus (chicken) | S100A4 | XP_004948276.1 |
| Canis lupus familiaris (dog) | S100A4 | NP_001003161.1 |
| Bos taurus (cattle) | S100A4 | NP_777020.1 |
| Rattus norvegicus (Norway rat) | S100a4 | NP_036750.1 |
| Pan troglodytes (chimpanzee) | S100A4 | XP_001138744.1 |
Related articles in PubMed
The microRNA miR-124 inhibits vascular smooth muscle cell proliferation by targeting S100 calcium-binding protein A4 (S100A4).
Choe N, Kwon DH, Shin S, Kim YS, Kim YK, Kim J, Ahn Y, Eom GH, Kook H
FEBS letters591(7)1041-1052(2017 04)
Extracellular matrix remodelling in response to venous hypertension: proteomics of human varicose veins.
Barallobre-Barreiro J, Oklu R, Lynch M, Fava M, Baig F, Yin X, Barwari T, Potier DN, Albadawi H, Jahangiri M, Porter KE, Watkins MT, Misra S, Stoughton J, Mayr M
Cardiovascular research110(3)419-30(2016 06)
Involvement of fibroblast-specific protein 1 (S100A4) and matrix metalloproteinase-13 (MMP-13) in CCl4-induced reversible liver fibrosis.
Louka ML, Ramzy MM
Gene579(1)29-33(2016 Mar)
S100A4 upregulation suppresses tissue ossification and enhances matrix degradation in experimental periodontitis models.
Zhou M, Li ZQ, Wang ZL
Acta pharmacologica Sinica36(11)1388-94(2015 Nov)
GeneRIFs: Gene References Into Functions What's a GeneRIF?
Data indicate that microRNA miR-124 targets S100 calcium-binding protein A4 (S100A4) 3' UTR and regulates vascular smooth muscle cell proliferation.
Title: The microRNA miR-124 inhibits vascular smooth muscle cell proliferation by targeting S100 calcium-binding protein A4 (S100A4).
Results show S100A4 expression increasing during fibrotic stage and declining during resolution suggesting it as a good marker for liver fibrogenesis.
Title: Involvement of fibroblast-specific protein 1 (S100A4) and matrix metalloproteinase-13 (MMP-13) in CCl4-induced reversible liver fibrosis.
S100A4 is upregulated in the experimental rat periodontitis.
Title: S100A4 upregulation suppresses tissue ossification and enhances matrix degradation in experimental periodontitis models.
found a significant increase in the expression of S100A4 in vitreous samples of rats with diabetic retinopathy
Title: S100A4 is upregulated in proliferative diabetic retinopathy and correlates with markers of angiogenesis and fibrogenesis.
TG2 regulates S100A4-mediated mammary tumor cell migration.
Title: The role of TG2 in regulating S100A4-mediated mammary tumour cell migration.
The following S100a4 gene cDNA ORF clone sequences were retrieved from the NCBI Reference Sequence Database (RefSeq). These sequences represent the protein coding region of the S100a4 cDNA ORF which is encoded by the open reading frame (ORF) sequence. ORF sequences can be delivered in our standard vector, pcDNA3.1+/C-(K)DYK or the vector of your choice as an expression/transfection-ready ORF clone. Not the clone you want? Click here to find your clone.
| CloneID | ORa00477 | |
| Clone ID Related Accession (Same CDS sequence) | NM_012618.2 , XM_006232592.3 | |
| Accession Version | NM_012618.2 Latest version! | Documents for ORF clone product in default vector |
| Sequence Information | ORF Nucleotide Sequence (Length: 306bp) Protein sequence SNP |
|
| Vector | pcDNA3.1+/C-(K)DYK or customized vector |  User Manual |
| Clone information | Clone Map | MSDS |
| Tag on pcDNA3.1+/C-(K)DYK | C terminal DYKDDDDK tags | |
| ORF Insert Method | CloneEZ™ Seamless cloning technology | |
| Insert Structure | linear | |
| Update Date | 2019-09-02 | |
| Organism | Rattus norvegicus(Norway rat) | |
| Product | protein S100-A4 | |
| Comment | Comment: PROVISIONAL REFSEQ: This record has not yet been subject to final NCBI review. The reference sequence was derived from J03628.1. On Aug 31, 2012 this sequence version replaced NM_012618.1. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Gene record to access additional publications. ##Evidence-Data-START## Transcript exon combination :: J03628.1, FQ215053.1 [ECO:0000332] RNAseq introns :: single sample supports all introns SAMD00052296, SAMD00052297 [ECO:0000348] ##Evidence-Data-END## | |
1 | ATGGCGAGAC CCTTGGAGGA GGCCCTGGAT GTAATAGTGT CCACCTTCCA CAAATACTCA |
The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.
| RefSeq | NP_036750.1 |
| CDS | 53..358 |
| Translation |
Target ORF information:
Target ORF information:
|
 NM_012618.2 |
ORF Insert Sequence:
1 | ATGGCGAGAC CCTTGGAGGA GGCCCTGGAT GTAATAGTGT CCACCTTCCA CAAATACTCA |
The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.
| CloneID | ORa00477 | |
| Clone ID Related Accession (Same CDS sequence) | NM_012618.2 , XM_006232592.3 | |
| Accession Version | XM_006232592.3 Latest version! | Documents for ORF clone product in default vector |
| Sequence Information | ORF Nucleotide Sequence (Length: 306bp) Protein sequence SNP |
|
| Vector | pcDNA3.1+/C-(K)DYK or customized vector | User Manual |
| Clone information | Clone Map | MSDS |
| Tag on pcDNA3.1+/C-(K)DYK | C terminal DYKDDDDK tags | |
| ORF Insert Method | CloneEZ™ Seamless cloning technology | |
| Insert Structure | linear | |
| Update Date | 2016-07-25 | |
| Organism | Rattus norvegicus(Norway rat) | |
| Product | protein S100-A4 isoform X1 | |
| Comment | Comment: MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_005101.4) annotated using gene prediction method: Gnomon, supported by mRNA and EST evidence. Also see: Documentation of NCBI's Annotation Process On Jul 26, 2016 this sequence version replaced XM_006232592.2. ##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Version :: Rattus norvegicus Annotation Release 106 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 7.1 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END## | |
1 | ATGGCGAGAC CCTTGGAGGA GGCCCTGGAT GTAATAGTGT CCACCTTCCA CAAATACTCA |
The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.
| RefSeq | XP_006232654.1 |
| CDS | 126..431 |
| Translation |
Target ORF information:
Target ORF information:
|
XM_006232592.3 |
ORF Insert Sequence:
1 | ATGGCGAGAC CCTTGGAGGA GGCCCTGGAT GTAATAGTGT CCACCTTCCA CAAATACTCA |
The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.
 |
The microRNA miR-124 inhibits vascular smooth muscle cell proliferation by targeting S100 calcium-binding protein A4 (S100A4). |
|
Extracellular matrix remodelling in response to venous hypertension: proteomics of human varicose veins. |
|
Involvement of fibroblast-specific protein 1 (S100A4) and matrix metalloproteinase-13 (MMP-13) in CCl4-induced reversible liver fibrosis. |
|
S100A4 upregulation suppresses tissue ossification and enhances matrix degradation in experimental periodontitis models. |