Gene Symbol | Cby1 |
Entrez Gene ID | 246768 |
Full Name | chibby family member 1, beta catenin antagonist |
Synonyms | Pgea1 |
General protein information |
|
Gene Type | protein-coding |
Organism | Rattus norvegicus(Norway rat) |
Genome |
ORF » Species Summary » Rattus norvegicus » Cby1 cDNA ORF clone
gRNAs
Gene Symbol | Cby1 |
Entrez Gene ID | 246768 |
Full Name | chibby family member 1, beta catenin antagonist |
Synonyms | Pgea1 |
General protein information |
|
Gene Type | protein-coding |
Organism | Rattus norvegicus(Norway rat) |
Genome |
mRNA | Protein | Name |
---|---|---|
XM_006241967.3 | XP_006242029.1 | protein chibby homolog 1 isoform X1 |
NM_145676.1 | NP_663709.1 | protein chibby homolog 1 |
Pan troglodytes (chimpanzee) | CBY1 | XP_003317289.1 |
Rattus norvegicus (Norway rat) | Cby1 | NP_663709.1 |
Danio rerio (zebrafish) | cby1 | NP_001003838.1 |
Homo sapiens (human) | CBY1 | NP_001002880.2 |
Canis lupus familiaris (dog) | CBY1 | XP_538373.3 |
Bos taurus (cattle) | CBY1 | NP_777164.1 |
Mus musculus (house mouse) | Cby1 | NP_082910.1 |
Gallus gallus (chicken) | CBY1 | NP_001265078.1 |
Xenopus tropicalis (tropical clawed frog) | cby1 | NP_001016253.1 |
Drosophila chibby is required for basal body formation and ciliogenesis but not for Wg signaling.
Enjolras C, Thomas J, Chhin B, Cortier E, Duteyrat JL, Soulavie F, Kernan MJ, Lauren?on A, Durand B
The Journal of cell biology197(2)313-25(2012 Apr)
A Wnt/beta-catenin pathway antagonist Chibby binds Cenexin at the distal end of mother centrioles and functions in primary cilia formation.
Steere N, Chae V, Burke M, Li FQ, Takemaru K, Kuriyama R
PloS one7(7)e41077(2012)
Structural characterization of partially disordered human Chibby: insights into its function in the Wnt-signaling pathway.
Mokhtarzada S, Yu C, Brickenden A, Choy WY
Biochemistry50(5)715-26(2011 Feb)
Inactivation of Chibby affects function of motile airway cilia.
Voronina VA, Takemaru K, Treuting P, Love D, Grubb BR, Hajjar AM, Adams A, Li FQ, Moon RT
The Journal of cell biology185(2)225-33(2009 Apr)
Chibby promotes adipocyte differentiation through inhibition of beta-catenin signaling.
Li FQ, Singh AM, Mofunanya A, Love D, Terada N, Moon RT, Takemaru K
Molecular and cellular biology27(12)4347-54(2007 Jun)
GeneRIFs: Gene References Into Functions What's a GeneRIF?
The following Cby1 gene cDNA ORF clone sequences were retrieved from the NCBI Reference Sequence Database (RefSeq). These sequences represent the protein coding region of the Cby1 cDNA ORF which is encoded by the open reading frame (ORF) sequence. ORF sequences can be delivered in our standard vector, pcDNA3.1+/C-(K)DYK or the vector of your choice as an expression/transfection-ready ORF clone. Not the clone you want? Click here to find your clone.
CloneID | ORa02605 | |
Clone ID Related Accession (Same CDS sequence) | NM_145676.1 | |
Accession Version | NM_145676.1 Latest version! | Documents for ORF clone product in default vector |
Sequence Information | ORF Nucleotide Sequence (Length: 384bp) Protein sequence SNP |
|
Vector | pcDNA3.1-C-(k)DYK or customized vector | ![]() |
Clone information | Clone Map | ![]() |
Tag on pcDNA3.1+/C-(K)DYK | C terminal DYKDDDDK tags | |
ORF Insert Method | CloneEZ™ Seamless cloning technology | |
Insert Structure | linear | |
Update Date | 2019-04-18 | |
Organism | Rattus norvegicus(Norway rat) | |
Product | protein chibby homolog 1 | |
Comment | Comment: PROVISIONAL REFSEQ: This record has not yet been subject to final NCBI review. The reference sequence was derived from AF393211.1. ##Evidence-Data-START## Transcript exon combination :: AF393211.1, BP501090.1 [ECO:0000332] RNAseq introns :: single sample supports all introns SAMD00052296, SAMD00052297 [ECO:0000348] ##Evidence-Data-END## |
1 | ATGCCTCTCT TTGGGAGCAT ATTCAGCCCG AAGAAGACTC CTCCTCGGAA GTCGGCCTCT |
The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.
RefSeq | NP_663709.1 |
CDS | 89..472 |
Translation |
Target ORF information:
Target ORF information:
|
![]() |
1 | ATGCCTCTCT TTGGGAGCAT ATTCAGCCCG AAGAAGACTC CTCCTCGGAA GTCGGCCTCT |
The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.
CloneID | ORa30546 | |
Clone ID Related Accession (Same CDS sequence) | XM_006241967.3 | |
Accession Version | XM_006241967.3 Latest version! | Documents for ORF clone product in default vector |
Sequence Information | ORF Nucleotide Sequence (Length: 384bp) Protein sequence SNP |
|
Vector | pcDNA3.1-C-(k)DYK or customized vector | ![]() |
Clone information | Clone Map | ![]() |
Tag on pcDNA3.1+/C-(K)DYK | C terminal DYKDDDDK tags | |
ORF Insert Method | CloneEZ™ Seamless cloning technology | |
Insert Structure | linear | |
Update Date | 2016-07-25 | |
Organism | Rattus norvegicus(Norway rat) | |
Product | protein chibby homolog 1 isoform X1 | |
Comment | Comment: MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_005106.4) annotated using gene prediction method: Gnomon, supported by mRNA and EST evidence. Also see: Documentation of NCBI's Annotation Process On Jul 26, 2016 this sequence version replaced XM_006241967.2. ##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Version :: Rattus norvegicus Annotation Release 106 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 7.1 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END## |
1 | ATGCCTCTCT TTGGGAGCAT ATTCAGCCCG AAGAAGACTC CTCCTCGGAA GTCGGCCTCT |
The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.
RefSeq | XP_006242029.1 |
CDS | 204..587 |
Translation |
Target ORF information:
Target ORF information:
|
![]() |
1 | ATGCCTCTCT TTGGGAGCAT ATTCAGCCCG AAGAAGACTC CTCCTCGGAA GTCGGCCTCT |
The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.
Drosophila chibby is required for basal body formation and ciliogenesis but not for Wg signaling. |
A Wnt/beta-catenin pathway antagonist Chibby binds Cenexin at the distal end of mother centrioles and functions in primary cilia formation. |
Structural characterization of partially disordered human Chibby: insights into its function in the Wnt-signaling pathway. |
Inactivation of Chibby affects function of motile airway cilia. |
Chibby promotes adipocyte differentiation through inhibition of beta-catenin signaling. |