• English
  • Sign In
    Please Sign In
    Sign In
    New to GenScript?
    Register
  • Contact Us
×
Contact us now: +1-877-436-7274

Cby1 cDNA ORF clone, Rattus norvegicus(Norway rat)

Summary

Gene Symbol Cby1
Entrez Gene ID 246768
Full Name chibby family member 1, beta catenin antagonist
Synonyms Pgea1
General protein information
Preferred Names

chibby family member 1, beta catenin antagonist

Names

protein chibby homolog 1
PIGEA-14
PKD2 interactor, Golgi and endoplasmic reticulum-associated 1
PKD2 interactor, golgi and endoplasmic reticulum associated 1
chibby homolog 1
cytosolic leucine-rich protein
Gene Type protein-coding
Organism Rattus norvegicus(Norway rat)
Genome

7

7q34

Reference Sequences (RefSeq)

mRNA and Protein(s)

mRNA Protein Name
XM_006241967.3 XP_006242029.1 protein chibby homolog 1 isoform X1
NM_145676.1 NP_663709.1 protein chibby homolog 1

Pathways from BioSystems


Homologies


Pan troglodytes (chimpanzee) CBY1 XP_003317289.1
Rattus norvegicus (Norway rat) Cby1 NP_663709.1
Danio rerio (zebrafish) cby1 NP_001003838.1
Homo sapiens (human) CBY1 NP_001002880.2
Canis lupus familiaris (dog) CBY1 XP_538373.3
Bos taurus (cattle) CBY1 NP_777164.1
Mus musculus (house mouse) Cby1 NP_082910.1
Gallus gallus (chicken) CBY1 NP_001265078.1
Xenopus tropicalis (tropical clawed frog) cby1 NP_001016253.1

Gene Ontology


Bibliography

Related articles in PubMed

Drosophila chibby is required for basal body formation and ciliogenesis but not for Wg signaling.
Enjolras C, Thomas J, Chhin B, Cortier E, Duteyrat JL, Soulavie F, Kernan MJ, Lauren?on A, Durand B
The Journal of cell biology197(2)313-25(2012 Apr)

A Wnt/beta-catenin pathway antagonist Chibby binds Cenexin at the distal end of mother centrioles and functions in primary cilia formation.
Steere N, Chae V, Burke M, Li FQ, Takemaru K, Kuriyama R
PloS one7(7)e41077(2012)

Structural characterization of partially disordered human Chibby: insights into its function in the Wnt-signaling pathway.
Mokhtarzada S, Yu C, Brickenden A, Choy WY
Biochemistry50(5)715-26(2011 Feb)

Inactivation of Chibby affects function of motile airway cilia.
Voronina VA, Takemaru K, Treuting P, Love D, Grubb BR, Hajjar AM, Adams A, Li FQ, Moon RT
The Journal of cell biology185(2)225-33(2009 Apr)

Chibby promotes adipocyte differentiation through inhibition of beta-catenin signaling.
Li FQ, Singh AM, Mofunanya A, Love D, Terada N, Moon RT, Takemaru K
Molecular and cellular biology27(12)4347-54(2007 Jun)

GeneRIFs: Gene References Into Functions What's a GeneRIF?

The following Cby1 gene cDNA ORF clone sequences were retrieved from the NCBI Reference Sequence Database (RefSeq). These sequences represent the protein coding region of the Cby1 cDNA ORF which is encoded by the open reading frame (ORF) sequence. ORF sequences can be delivered in our standard vector, pcDNA3.1+/C-(K)DYK or the vector of your choice as an expression/transfection-ready ORF clone. Not the clone you want? Click here to find your clone.

***CloneID Accession No. Definition **Vector *Turnaround time Price (USD) Select
ORa02605 NM_145676.1
Latest version!		 Rattus norvegicus chibby family member 1, beta catenin antagonist (Cby1), mRNA. pcDNA3.1-C-(k)DYK or customized vector 7-9 $69.30
$99.00
ORa30546 XM_006241967.3
Latest version!		 Rattus norvegicus chibby family member 1, beta catenin antagonist (Cby1), transcript variant X1, mRNA. pcDNA3.1-C-(k)DYK or customized vector 7-9 $69.30
$99.00

ORF Online Only Promotion

Next-day Shipping ORF Clones ( in default vector with tag)
1 Clone 30% OFF
2-4 Clone 40% OFF
5 or more Clone 50% OFF
All Other ORF Clones
30% OFF

*Business Day

** You may select a custom vector to replace pcDNA3.1+/C-(K)DYK after clone is added to cart.

** GenScript guarantees 100% sequence accuracy of all synthetic DNA constructs we deliver, but we do not guarantee protein expression in your experimental system. Protein expression is influenced by many factors that may vary between experiments or laboratories. In addition, please pay attention to the signal peptide, propeptide and transit peptide in target ORF, which may affect the choice of vector (N/C terminal tag vector).

***One clone ID might be correlated to multiple accession numbers, which share the same CDS sequence.

Reference Sequences (Refseq)


CloneID ORa02605
Clone ID Related Accession (Same CDS sequence) NM_145676.1
Accession Version NM_145676.1 Latest version! Documents for ORF clone product in default vector
Sequence Information ORF Nucleotide Sequence (Length: 384bp)
Protein sequence
SNP
Vector pcDNA3.1+/C-(K)DYK or customized vector User Manual
Clone information Clone Map MSDS
Tag on pcDNA3.1+/C-(K)DYK C terminal DYKDDDDK tags
ORF Insert Method CloneEZ™ Seamless cloning technology
Insert Structure linear
Update Date 2019-04-18
Organism Rattus norvegicus(Norway rat)
Product protein chibby homolog 1
Comment Comment: PROVISIONAL REFSEQ: This record has not yet been subject to final NCBI review. The reference sequence was derived from AF393211.1. ##Evidence-Data-START## Transcript exon combination :: AF393211.1, BP501090.1 [ECO:0000332] RNAseq introns :: single sample supports all introns SAMD00052296, SAMD00052297 [ECO:0000348] ##Evidence-Data-END## 

1
61
121
181
241
301
361
ATGCCTCTCT TTGGGAGCAT ATTCAGCCCG AAGAAGACTC CTCCTCGGAA GTCGGCCTCT 
CTCTCTAACC TGCACTCTTT AGATCGATCA ACGCGAGAAC TGGAGCTGGG TCTTGACTAT 
GGAACTCCTA CCATGAACCT GGCGGGGCAA AGCCTGAAGT TTGAAAATGG CCAGTGGGTG 
GCAGACTCAG TGATTAGTGG GGGTGTGGAC CGGAGGGAAA CTCAGCGCCT GCGCAAACGA 
AACCAGCAGT TGGAAGAAGA GAACAATCTC CTGCGGCTGA AGGTGGACAT CCTGCTGGAC 
ATGCTTTCAG AAACCACTGC TGAGTCCCAC TTAAAGGACA AGGAACTGGA TGAACTGAAG 
ATTACCAACC GCAGGAGGAA GTGA

The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.

RefSeq NP_663709.1
CDS89..472
Translation

Target ORF information:

RefSeq Version NM_145676.1
Organism Rattus norvegicus(Norway rat)
Definition Rattus norvegicus chibby family member 1, beta catenin antagonist (Cby1), mRNA.

Target ORF information:

Epitope DYKDDDDK
Bacterial selection AMPR
Mammalian selection NeoR
Vector pcDNA3.1+/C-(K)DYK
 NM_145676.1

ORF Insert Sequence:

1
61
121
181
241
301
361
ATGCCTCTCT TTGGGAGCAT ATTCAGCCCG AAGAAGACTC CTCCTCGGAA GTCGGCCTCT 
CTCTCTAACC TGCACTCTTT AGATCGATCA ACGCGAGAAC TGGAGCTGGG TCTTGACTAT 
GGAACTCCTA CCATGAACCT GGCGGGGCAA AGCCTGAAGT TTGAAAATGG CCAGTGGGTG 
GCAGACTCAG TGATTAGTGG GGGTGTGGAC CGGAGGGAAA CTCAGCGCCT GCGCAAACGA 
AACCAGCAGT TGGAAGAAGA GAACAATCTC CTGCGGCTGA AGGTGGACAT CCTGCTGGAC 
ATGCTTTCAG AAACCACTGC TGAGTCCCAC TTAAAGGACA AGGAACTGGA TGAACTGAAG 
ATTACCAACC GCAGGAGGAA GTGA

The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.

CloneID ORa30546
Clone ID Related Accession (Same CDS sequence) XM_006241967.3
Accession Version XM_006241967.3 Latest version! Documents for ORF clone product in default vector
Sequence Information ORF Nucleotide Sequence (Length: 384bp)
Protein sequence
SNP
Vector pcDNA3.1+/C-(K)DYK or customized vector User Manual
Clone information Clone Map MSDS
Tag on pcDNA3.1+/C-(K)DYK C terminal DYKDDDDK tags
ORF Insert Method CloneEZ™ Seamless cloning technology
Insert Structure linear
Update Date 2016-07-25
Organism Rattus norvegicus(Norway rat)
Product protein chibby homolog 1 isoform X1
Comment Comment: MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_005106.4) annotated using gene prediction method: Gnomon, supported by mRNA and EST evidence. Also see: Documentation of NCBI's Annotation Process On Jul 26, 2016 this sequence version replaced XM_006241967.2. ##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Version :: Rattus norvegicus Annotation Release 106 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 7.1 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END## 

1
61
121
181
241
301
361
ATGCCTCTCT TTGGGAGCAT ATTCAGCCCG AAGAAGACTC CTCCTCGGAA GTCGGCCTCT 
CTCTCTAACC TGCACTCTTT AGATCGGTCA ACGCGAGAAC TGGAGCTGGG TCTTGACTAT 
GGAACTCCTA CCATGAACCT GGCGGGGCAA AGCCTGAAGT TTGAAAATGG CCAGTGGGTG 
GCAGACTCAG TGATTAGTGG GGGTGTGGAC CGGAGGGAAA CTCAGCGCCT GCGCAAACGA 
AACCAGCAGT TGGAAGAAGA GAACAATCTC CTGCGGCTGA AGGTGGACAT CCTGCTGGAC 
ATGCTTTCAG AAACCACTGC TGAGTCCCAC TTAAAGGACA AGGAACTGGA TGAACTGAAG 
ATTACCAACC GCAGGAGGAA GTGA

The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.

RefSeq XP_006242029.1
CDS204..587
Translation

Target ORF information:

RefSeq Version XM_006241967.3
Organism Rattus norvegicus(Norway rat)
Definition Rattus norvegicus chibby family member 1, beta catenin antagonist (Cby1), transcript variant X1, mRNA.

Target ORF information:

Epitope DYKDDDDK
Bacterial selection AMPR
Mammalian selection NeoR
Vector pcDNA3.1+/C-(K)DYK
 XM_006241967.3

ORF Insert Sequence:

1
61
121
181
241
301
361
ATGCCTCTCT TTGGGAGCAT ATTCAGCCCG AAGAAGACTC CTCCTCGGAA GTCGGCCTCT 
CTCTCTAACC TGCACTCTTT AGATCGGTCA ACGCGAGAAC TGGAGCTGGG TCTTGACTAT 
GGAACTCCTA CCATGAACCT GGCGGGGCAA AGCCTGAAGT TTGAAAATGG CCAGTGGGTG 
GCAGACTCAG TGATTAGTGG GGGTGTGGAC CGGAGGGAAA CTCAGCGCCT GCGCAAACGA 
AACCAGCAGT TGGAAGAAGA GAACAATCTC CTGCGGCTGA AGGTGGACAT CCTGCTGGAC 
ATGCTTTCAG AAACCACTGC TGAGTCCCAC TTAAAGGACA AGGAACTGGA TGAACTGAAG 
ATTACCAACC GCAGGAGGAA GTGA

The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.

PubMed

book

Drosophila chibby is required for basal body formation and ciliogenesis but not for Wg signaling.
The Journal of cell biology197(2)313-25(2012 Apr)
Enjolras C,Thomas J,Chhin B,Cortier E,Duteyrat JL,Soulavie F,Kernan MJ,Lauren?on A,Durand B


book

A Wnt/beta-catenin pathway antagonist Chibby binds Cenexin at the distal end of mother centrioles and functions in primary cilia formation.
PloS one7(7)e41077(2012)
Steere N,Chae V,Burke M,Li FQ,Takemaru K,Kuriyama R


book

Structural characterization of partially disordered human Chibby: insights into its function in the Wnt-signaling pathway.
Biochemistry50(5)715-26(2011 Feb)
Mokhtarzada S,Yu C,Brickenden A,Choy WY


book

Inactivation of Chibby affects function of motile airway cilia.
The Journal of cell biology185(2)225-33(2009 Apr)
Voronina VA,Takemaru K,Treuting P,Love D,Grubb BR,Hajjar AM,Adams A,Li FQ,Moon RT


book

Chibby promotes adipocyte differentiation through inhibition of beta-catenin signaling.
Molecular and cellular biology27(12)4347-54(2007 Jun)
Li FQ,Singh AM,Mofunanya A,Love D,Terada N,Moon RT,Takemaru K