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Mamdc4 cDNA ORF clone, Rattus norvegicus(Norway rat)

Summary

Gene Symbol Mamdc4
Entrez Gene ID 252882
Full Name MAM domain containing 4
Synonyms Aegp
General protein information
Preferred Names

MAM domain containing 4

Names

apical endosomal glycoprotein
MAM domain-containing protein 4
apical early endosomal glycoprotein
Gene Type protein-coding
Organism Rattus norvegicus(Norway rat)
Genome

3

3p13
Summary glycoprotein localized to the apical endosomal tubules of intestinal epithelial cells; may play a role in intestinal transport [RGD, Feb 2006].

Reference Sequences (RefSeq)

mRNA and Protein(s)

mRNA Protein Name
NM_145768.1 NP_665711.1 apical endosomal glycoprotein precursor

Pathways from BioSystems


Homologies


Homo sapiens (human) MAMDC4 NP_996803.2
Canis lupus familiaris (dog) MAMDC4 XP_005625136.1
Rattus norvegicus (Norway rat) Mamdc4 NP_665711.1
Gallus gallus (chicken) MAMDC4 XP_004945772.1
Danio rerio (zebrafish) LOC797166 XP_001337624.4
Xenopus tropicalis (tropical clawed frog) mamdc4 XP_002940785.2
Pan troglodytes (chimpanzee) MAMDC4 XP_528464.3
MAMDC4 XP_002799962.1
Bos taurus (cattle) MAMDC4 NP_001137345.1
Mus musculus (house mouse) Mamdc4 NP_001074668.2

Gene Ontology


Bibliography

Related articles in PubMed

Regulation of tight junction assembly and epithelial polarity by a resident protein of apical endosomes.
McCarter SD, Johnson DL, Kitt KN, Donohue C, Adams A, Wilson JM
Traffic (Copenhagen, Denmark)11(6)856-66(2010 Jun)

Molecular characterization of an apical early endosomal glycoprotein from developing rat intestinal epithelial cells.
Speelman BA, Allen K, Grounds TL, Neutra MR, Kirchhausen T, Wilson JM
The Journal of biological chemistry270(4)1583-8(1995 Jan)

GeneRIFs: Gene References Into Functions What's a GeneRIF?

endotubin regulates trafficking of polarity proteins and tight junction components out of the endosomal compartment
Title: Regulation of tight junction assembly and epithelial polarity by a resident protein of apical endosomes.

The following Mamdc4 gene cDNA ORF clone sequences were retrieved from the NCBI Reference Sequence Database (RefSeq). These sequences represent the protein coding region of the Mamdc4 cDNA ORF which is encoded by the open reading frame (ORF) sequence. ORF sequences can be delivered in our standard vector, pcDNA3.1+/C-(K)DYK or the vector of your choice as an expression/transfection-ready ORF clone. Not the clone you want? Click here to find your clone.

***CloneID Accession No. Definition **Vector *Turnaround time Price (USD) Select
ORa02651 NM_145768.1
Latest version!		 Rattus norvegicus MAM domain containing 4 (Mamdc4), mRNA. pcDNA3.1+/C-(K)DYK or customized vector 20 $895.30
$1279.00

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** You may select a custom vector to replace pcDNA3.1+/C-(K)DYK after clone is added to cart.

** GenScript guarantees 100% sequence accuracy of all synthetic DNA constructs we deliver, but we do not guarantee protein expression in your experimental system. Protein expression is influenced by many factors that may vary between experiments or laboratories. In addition, please pay attention to the signal peptide, propeptide and transit peptide in target ORF, which may affect the choice of vector (N/C terminal tag vector).

***One clone ID might be correlated to multiple accession numbers, which share the same CDS sequence.

Reference Sequences (Refseq)


CloneID ORa02651
Clone ID Related Accession (Same CDS sequence) NM_145768.1
Accession Version NM_145768.1 Latest version! Documents for ORF clone product in default vector
Sequence Information ORF Nucleotide Sequence (Length: 3651bp)
Protein sequence
SNP
Vector pcDNA3.1+/C-(K)DYK or customized vector User Manual
Clone information Clone Map MSDS
Tag on pcDNA3.1+/C-(K)DYK C terminal DYKDDDDK tags
ORF Insert Method CloneEZ™ Seamless cloning technology
Insert Structure linear
Update Date 2019-12-25
Organism Rattus norvegicus(Norway rat)
Product apical endosomal glycoprotein precursor
Comment Comment: PROVISIONAL REFSEQ: This record has not yet been subject to final NCBI review. The reference sequence was derived from L37380.1. ##Evidence-Data-START## Transcript exon combination :: L37380.1 [ECO:0000332] RNAseq introns :: mixed/partial sample support SAMD00052296, SAMD00052297 [ECO:0000350] ##Evidence-Data-END## 

1
61
121
181
241
301
361
421
481
541
601
661
721
781
841
901
961
1021
1081
1141
1201
1261
1321
1381
1441
1501
1561
1621
1681
1741
1801
1861
1921
1981
2041
2101
2161
2221
2281
2341
2401
2461
2521
2581
2641
2701
2761
2821
2881
2941
3001
3061
3121
3181
3241
3301
3361
3421
3481
3541
3601
ATGTGCCTGC CTAGCTGCCT CCTCTCAATC TGGGTCCTAT TTATGGCTGC ACAGTCTCTA 
GGCAAGACCT GGGTCCCTGA CCACTGCAGA AGCCCCACCG AAGCTACGTG CAACTTTGTG 
TGTGACTGTG GAGACTGTTC AGATGAGGCT CAGTGTGGTT TCCACGGTGC CTCAACTACC 
CCAAACACCC CCTTCACCTG CAACTTTGAG CAGGATCCCT GTGGCTGGCA GGACATCAGC 
ACCTCGGGCT ATCGATGGCT TCGAGACCGG GCAGGGGCAG GGCTGGATAG TTCTGGGCCC 
CATTCTGACC ATACACGTGG CACTGACTTG GGCTGGTACA TGGCTGTGGG AACCCATAGT 
GGGAAGGAGC CATCTACTCG GACTTTGCGC TCTCCTGTCA TGCGTGAGGC AGCCCCCACC 
TGTGAACTGA GGCTCTGGTA CCACACTGAC TCTAGAGATG TCGCTGAGCT GCGGCTGGAT 
CTGACCCATG GTATGGAGAC ACTGACTCTA TGGCAGAGCT CGGGACCTTG GGGTCCCTGG 
CCTGGCAGGG AACTAGCAGT GAACACTGGC CGAATCCAGG GTGACTTCAA AGTGACATTT 
TCTGCCACTC GAAATGCTAC ACACAGGGGC GCTGTGGCCT TGGATGACAT GGAGTTCTGG 
GACTGTGGTC TGCCCATCCC TCAGGCCAGG TGTCCCCTGG GGCACCACCA CTGCCAGAAC 
AAAGCTTGTG TGGAGCCCCA CCAGCTCTGT GACGGTGAAG ACAACTGTGG AGACAGTTCT 
GATGAAGACC CGCTCATCTG CAGCCACCAC ATGGCCACCG ACTTTGAGAC AGGCCTAGGA 
CCATGGACCC AATTAGAGGG CTGGACACGG AACTTCAGTG CTGGCAGCAT GGTGAGCCCT 
GCCTGGCCCC ACCGAGATCA CAGCCGGAAT AGTGCATATG GCTTCTTTCT CGTCTCTGTG 
GCCAAGCCTG GCACCACTGC TGTCCTCTAC AGCCCTGAGT TCCAAGGCTC AGTCTCCTAC 
AACTGCTCGT TCACCTTCTA TTACTACCTG CATGGGTCTG AGGCCAACCA ATTCCAGCTC 
TTTGTGCAGG CACAGGGGCT CAACACCACC CAGCCTCCTG TCCTACTCCG AAGCCGCCAT 
GGAGAGTTGG GGACAGCCTG GGTCAGAGAC CGGGTTAACA TTCAAAGTGC CCATCCATTT 
CGGATCCTTC TTGCTGGGGA GACTGGTCCA GGAGGCTTCG TGGGCCTAGA CGACCTTATC 
ATGTCCAACC ACTGCATACT TGTTCCAGGT ATGTCCACCC TGCAGTCATC ACTTTCTGGA 
CCTGTGCCAT TGGCCCTCTA TCCCCAGACA TCCATCAAGC GAACCTGTGA CGCAGGACAT 
CTCTCCTGTG ACGAGCTGTG TGTGCCCCCG GAGCAGCTGT GTGATTTCCA GCAGCACTGT 
GCCGAAGGCG AGGATGAAGA GAAGTGTGGC ACCACGGACT TTGAGTCTGC CTCTGCTGGG 
GGCTGGGAGG ACATCAGTAT AGGAAAGCTA CAGTGGCAAC GGGCTGAAGC CCAGGAGAGC 
GGGAAGCCTG CCAGGGATAC CAACCGGAAT GCACCTGGGC ACTTCCTATC TCTGCGGAAG 
GCCTGGGGGC AGCTACGATC TGAGGCCCGG GCTCTCACAC CTACTCTGGG CCCCTCTGGC 
CCTCACTGTG AACTCCACAT GACTTACTAT TTTCACAGTC ATCCCCAAGG CTTCTTGGCA 
CTGGCTGTGG TGGAGAATGG CTTCCGGGAG CTGCTGTGGC AGGCTCCAAG CAGCAGCAGT 
GGGGGCTGGA CACTACAGAA GATTCTTCTT GGGGCACGGC GCTGGCCATT CCAGCTGGAG 
TTCGTCAGTC TGGTGGACTT GGATGGCCCT GGCCAACAGG GGGCTGGGGT GGATAATGTG 
ACCCTGAGAG ACTGCAACCC CATGGTGACC ACTGAGAGTG ACCAAGAGGT CTCCTGTAAC 
TTTGAACGGG ACTCCTGCAG CTGGCACACA GGCCACCTCA CAGATGCCCA CTGGCACCGT 
GTAAAAAGCC ACGGCTCTCA GTATGACCAC ACCACCGGCC AAGGTTTTTT CATGTTCCTG 
GATCCCATGG ACCCACCTGC TCGAGGCCAA GGTGCCCTGT TGCTCACAAG ACCCCAGGTG 
CCAGTTGTCC CCAAGGAATG TCTCAGCTTC TGGTACCATC TGCATGGGCC CCAGATTGGG 
ACACTGTGCT TGGCCATGAG GAGGGAGGGG GAGGAAGACA CACTACTGTG GTCCCGGTCA 
GGCACCCACG GCAACCGCTG GCACCAGGCT TGGGTCACTC TTCACCACCA GCTGCAGCCC 
AGCACCAAGT ACCAGTTGCT GTTTGAAGGC CTCCGGGATG GGTACCATGG CACAATGGGC 
CTGGATGACA TGGCTGTGCG GCCTGGCCCC TGCTGGGCCG CCAAGAGATG TTCCTTTGAA 
GACTCTGACT GTGGCTTCTC CCCAGGGGAC TGGGGGCTGT GGACACGCCA GAATAATGCC 
TCAGGCCTTG GTCCTTGGGG TCCTTGGATA GACCATACCA CAGGGACAGC CCAGGGGCAC 
TACATGGTGG TGGACACCAG CCCAAATTTA CTGCCCAAAG GTCATGTGGC CTCTCTGACT 
TCAGAGGAGC ACCCGCCCCT GTCCCGGCCT GCCTGCCTGT CCTTCTGGTA CCACCTGAGC 
TTCCACAATC CAGGCACCTT GAGGGTCTTC GTGGAAGAGA GCACAAGGCG CCAAGAGCTC 
AGCATCAGTG GCCATGGTGG ATTTGCGTGG CGCCTAGGCA GCGTGAATGT ACAGGCTGAG 
CAGGCCTGGA AGGTAGTGTT TGAGGCTATG GCTTCTGGCG TGGAACATTC CTACATGGCT 
CTGGATGACA TTTCCCTCCA AGATGGGCCC TGTGCTCAGC CAGGGTCCTG TGACTTTGAA 
TCTGGCCTGT GTGGGTGGAG CCACCTGCCT TGGCCTGGTC TGGGTGGGTA CAGCTGGGAC 
TGGAGCAGTG GAGCCACTCC ATCCCGGTAC CCCCGGCCTT CAGTGGACCA CACTGTGGGC 
ACAGAAGCAG GCCACTTCGC TTTCTTTGAA ACCAGCGTGC TAGGTCCTGG GGGCCAGGCA 
GCCTGGCTCG GCAGTGAGCC ACTGCCAGCA ACTGCAGTCT CCTGCCTCCA CTTCTGGTAC 
TACATGGGCT TTCCTGCGCA TTTCTACAAG GGTGAGTTGA GAGTGCTCCT GAGCAGTACC 
CAAGGACAGC TAGCTGTGTG GCACCGGGGT GGGCACTTGC GGGACCAGTG GCTACAAGTC 
CAGATTGAAG TGTCCAGCTC TGAGGAGTTC CAGATTGTTT TTGAAGCCAC TCTGGGTGGC 
CAGCCGGCTC TAGGGCCCAT TGCCCTTGAT GATGTGGAGT ACTTGGCTGG ACAACACTGC 
AAGCAACCTA CACCTAGCCA GGGTAGAGTG GCAGCACCCG TGTCTGTGCC GGTTGCAGTC 
GGAGGAGCCC TCCTCCTCTT CCTGTTGCTC CTGGGCCTTG GAGGTTGGCA CTGGCTGCAG 
AAGCAGCACC TCCCCTGCCA AAGTACAGAT GCAGCAGCCT CTGGCTTTGA CAATATCCTC 
TTCAATGCGG ATCAAGTTAC CCTCCCAGAA TCAATCACCA GTAACCCATA G

The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.

RefSeq NP_665711.1
CDS58..3708
Translation

Target ORF information:

RefSeq Version NM_145768.1
Organism Rattus norvegicus(Norway rat)
Definition Rattus norvegicus MAM domain containing 4 (Mamdc4), mRNA.

Target ORF information:

Epitope DYKDDDDK
Bacterial selection AMPR
Mammalian selection NeoR
Vector pcDNA3.1+/C-(K)DYK
 NM_145768.1

ORF Insert Sequence:

1
61
121
181
241
301
361
421
481
541
601
661
721
781
841
901
961
1021
1081
1141
1201
1261
1321
1381
1441
1501
1561
1621
1681
1741
1801
1861
1921
1981
2041
2101
2161
2221
2281
2341
2401
2461
2521
2581
2641
2701
2761
2821
2881
2941
3001
3061
3121
3181
3241
3301
3361
3421
3481
3541
3601
ATGTGCCTGC CTAGCTGCCT CCTCTCAATC TGGGTCCTAT TTATGGCTGC ACAGTCTCTA 
GGCAAGACCT GGGTCCCTGA CCACTGCAGA AGCCCCACCG AAGCTACGTG CAACTTTGTG 
TGTGACTGTG GAGACTGTTC AGATGAGGCT CAGTGTGGTT TCCACGGTGC CTCAACTACC 
CCAAACACCC CCTTCACCTG CAACTTTGAG CAGGATCCCT GTGGCTGGCA GGACATCAGC 
ACCTCGGGCT ATCGATGGCT TCGAGACCGG GCAGGGGCAG GGCTGGATAG TTCTGGGCCC 
CATTCTGACC ATACACGTGG CACTGACTTG GGCTGGTACA TGGCTGTGGG AACCCATAGT 
GGGAAGGAGC CATCTACTCG GACTTTGCGC TCTCCTGTCA TGCGTGAGGC AGCCCCCACC 
TGTGAACTGA GGCTCTGGTA CCACACTGAC TCTAGAGATG TCGCTGAGCT GCGGCTGGAT 
CTGACCCATG GTATGGAGAC ACTGACTCTA TGGCAGAGCT CGGGACCTTG GGGTCCCTGG 
CCTGGCAGGG AACTAGCAGT GAACACTGGC CGAATCCAGG GTGACTTCAA AGTGACATTT 
TCTGCCACTC GAAATGCTAC ACACAGGGGC GCTGTGGCCT TGGATGACAT GGAGTTCTGG 
GACTGTGGTC TGCCCATCCC TCAGGCCAGG TGTCCCCTGG GGCACCACCA CTGCCAGAAC 
AAAGCTTGTG TGGAGCCCCA CCAGCTCTGT GACGGTGAAG ACAACTGTGG AGACAGTTCT 
GATGAAGACC CGCTCATCTG CAGCCACCAC ATGGCCACCG ACTTTGAGAC AGGCCTAGGA 
CCATGGACCC AATTAGAGGG CTGGACACGG AACTTCAGTG CTGGCAGCAT GGTGAGCCCT 
GCCTGGCCCC ACCGAGATCA CAGCCGGAAT AGTGCATATG GCTTCTTTCT CGTCTCTGTG 
GCCAAGCCTG GCACCACTGC TGTCCTCTAC AGCCCTGAGT TCCAAGGCTC AGTCTCCTAC 
AACTGCTCGT TCACCTTCTA TTACTACCTG CATGGGTCTG AGGCCAACCA ATTCCAGCTC 
TTTGTGCAGG CACAGGGGCT CAACACCACC CAGCCTCCTG TCCTACTCCG AAGCCGCCAT 
GGAGAGTTGG GGACAGCCTG GGTCAGAGAC CGGGTTAACA TTCAAAGTGC CCATCCATTT 
CGGATCCTTC TTGCTGGGGA GACTGGTCCA GGAGGCTTCG TGGGCCTAGA CGACCTTATC 
ATGTCCAACC ACTGCATACT TGTTCCAGGT ATGTCCACCC TGCAGTCATC ACTTTCTGGA 
CCTGTGCCAT TGGCCCTCTA TCCCCAGACA TCCATCAAGC GAACCTGTGA CGCAGGACAT 
CTCTCCTGTG ACGAGCTGTG TGTGCCCCCG GAGCAGCTGT GTGATTTCCA GCAGCACTGT 
GCCGAAGGCG AGGATGAAGA GAAGTGTGGC ACCACGGACT TTGAGTCTGC CTCTGCTGGG 
GGCTGGGAGG ACATCAGTAT AGGAAAGCTA CAGTGGCAAC GGGCTGAAGC CCAGGAGAGC 
GGGAAGCCTG CCAGGGATAC CAACCGGAAT GCACCTGGGC ACTTCCTATC TCTGCGGAAG 
GCCTGGGGGC AGCTACGATC TGAGGCCCGG GCTCTCACAC CTACTCTGGG CCCCTCTGGC 
CCTCACTGTG AACTCCACAT GACTTACTAT TTTCACAGTC ATCCCCAAGG CTTCTTGGCA 
CTGGCTGTGG TGGAGAATGG CTTCCGGGAG CTGCTGTGGC AGGCTCCAAG CAGCAGCAGT 
GGGGGCTGGA CACTACAGAA GATTCTTCTT GGGGCACGGC GCTGGCCATT CCAGCTGGAG 
TTCGTCAGTC TGGTGGACTT GGATGGCCCT GGCCAACAGG GGGCTGGGGT GGATAATGTG 
ACCCTGAGAG ACTGCAACCC CATGGTGACC ACTGAGAGTG ACCAAGAGGT CTCCTGTAAC 
TTTGAACGGG ACTCCTGCAG CTGGCACACA GGCCACCTCA CAGATGCCCA CTGGCACCGT 
GTAAAAAGCC ACGGCTCTCA GTATGACCAC ACCACCGGCC AAGGTTTTTT CATGTTCCTG 
GATCCCATGG ACCCACCTGC TCGAGGCCAA GGTGCCCTGT TGCTCACAAG ACCCCAGGTG 
CCAGTTGTCC CCAAGGAATG TCTCAGCTTC TGGTACCATC TGCATGGGCC CCAGATTGGG 
ACACTGTGCT TGGCCATGAG GAGGGAGGGG GAGGAAGACA CACTACTGTG GTCCCGGTCA 
GGCACCCACG GCAACCGCTG GCACCAGGCT TGGGTCACTC TTCACCACCA GCTGCAGCCC 
AGCACCAAGT ACCAGTTGCT GTTTGAAGGC CTCCGGGATG GGTACCATGG CACAATGGGC 
CTGGATGACA TGGCTGTGCG GCCTGGCCCC TGCTGGGCCG CCAAGAGATG TTCCTTTGAA 
GACTCTGACT GTGGCTTCTC CCCAGGGGAC TGGGGGCTGT GGACACGCCA GAATAATGCC 
TCAGGCCTTG GTCCTTGGGG TCCTTGGATA GACCATACCA CAGGGACAGC CCAGGGGCAC 
TACATGGTGG TGGACACCAG CCCAAATTTA CTGCCCAAAG GTCATGTGGC CTCTCTGACT 
TCAGAGGAGC ACCCGCCCCT GTCCCGGCCT GCCTGCCTGT CCTTCTGGTA CCACCTGAGC 
TTCCACAATC CAGGCACCTT GAGGGTCTTC GTGGAAGAGA GCACAAGGCG CCAAGAGCTC 
AGCATCAGTG GCCATGGTGG ATTTGCGTGG CGCCTAGGCA GCGTGAATGT ACAGGCTGAG 
CAGGCCTGGA AGGTAGTGTT TGAGGCTATG GCTTCTGGCG TGGAACATTC CTACATGGCT 
CTGGATGACA TTTCCCTCCA AGATGGGCCC TGTGCTCAGC CAGGGTCCTG TGACTTTGAA 
TCTGGCCTGT GTGGGTGGAG CCACCTGCCT TGGCCTGGTC TGGGTGGGTA CAGCTGGGAC 
TGGAGCAGTG GAGCCACTCC ATCCCGGTAC CCCCGGCCTT CAGTGGACCA CACTGTGGGC 
ACAGAAGCAG GCCACTTCGC TTTCTTTGAA ACCAGCGTGC TAGGTCCTGG GGGCCAGGCA 
GCCTGGCTCG GCAGTGAGCC ACTGCCAGCA ACTGCAGTCT CCTGCCTCCA CTTCTGGTAC 
TACATGGGCT TTCCTGCGCA TTTCTACAAG GGTGAGTTGA GAGTGCTCCT GAGCAGTACC 
CAAGGACAGC TAGCTGTGTG GCACCGGGGT GGGCACTTGC GGGACCAGTG GCTACAAGTC 
CAGATTGAAG TGTCCAGCTC TGAGGAGTTC CAGATTGTTT TTGAAGCCAC TCTGGGTGGC 
CAGCCGGCTC TAGGGCCCAT TGCCCTTGAT GATGTGGAGT ACTTGGCTGG ACAACACTGC 
AAGCAACCTA CACCTAGCCA GGGTAGAGTG GCAGCACCCG TGTCTGTGCC GGTTGCAGTC 
GGAGGAGCCC TCCTCCTCTT CCTGTTGCTC CTGGGCCTTG GAGGTTGGCA CTGGCTGCAG 
AAGCAGCACC TCCCCTGCCA AAGTACAGAT GCAGCAGCCT CTGGCTTTGA CAATATCCTC 
TTCAATGCGG ATCAAGTTAC CCTCCCAGAA TCAATCACCA GTAACCCATA G

The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.

PubMed

book

Regulation of tight junction assembly and epithelial polarity by a resident protein of apical endosomes.
Traffic (Copenhagen, Denmark)11(6)856-66(2010 Jun)
McCarter SD,Johnson DL,Kitt KN,Donohue C,Adams A,Wilson JM


book

Molecular characterization of an apical early endosomal glycoprotein from developing rat intestinal epithelial cells.
The Journal of biological chemistry270(4)1583-8(1995 Jan)
Speelman BA,Allen K,Grounds TL,Neutra MR,Kirchhausen T,Wilson JM