Ywhah cDNA ORF clone, Rattus norvegicus(Norway rat)
| Gene Symbol | Ywhah |
| Entrez Gene ID | 25576 |
| Full Name | tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, eta |
| Synonyms | 14-3-3e |
| General protein information |
|
| Gene Type | protein-coding |
| Organism | Rattus norvegicus(Norway rat) |
| Genome | |
| Summary | belongs to the 14-3-3 family of proteins; mediates signal transduction via activation of protein kinase C and calcium/calmodulin-dependent protein kinase II [RGD, Feb 2006]. |
mRNA and Protein(s)
| mRNA | Protein | Name |
|---|---|---|
| NM_013052.1 | NP_037184.1 | 14-3-3 protein eta |
| Homo sapiens (human) | YWHAH | NP_003396.1 |
| Pan troglodytes (chimpanzee) | YWHAH | XP_001151423.1 |
| Bos taurus (cattle) | YWHAH | NP_776917.2 |
| Mus musculus (house mouse) | Ywhah | NP_035868.1 |
| Danio rerio (zebrafish) | ywhah | NP_998329.1 |
| Rattus norvegicus (Norway rat) | Ywhah | NP_037184.1 |
| YWHAH | XP_001111998.1 | |
| Gallus gallus (chicken) | YWHAH | NP_001007840.1 |
| Canis lupus familiaris (dog) | YWHAH | XP_003433473.2 |
| Xenopus tropicalis (tropical clawed frog) | ywhah | NP_001016868.1 |
Related articles in PubMed
Quantitative proteomic analysis of human substantia nigra in Alzheimer's disease, Huntington's disease and Multiple sclerosis.
Chen S, Lu FF, Seeman P, Liu F
Neurochemical research37(12)2805-13(2012 Dec)
MHC class II-associated proteins in B-cell exosomes and potential functional implications for exosome biogenesis.
Buschow SI, van Balkom BW, Aalberts M, Heck AJ, Wauben M, Stoorvogel W
Immunology and cell biology88(8)851-6(2010 Nov-Dec)
Proteomic analysis of human parotid gland exosomes by multidimensional protein identification technology (MudPIT).
Gonzalez-Begne M, Lu B, Han X, Hagen FK, Hand AR, Melvin JE, Yates JR
Journal of proteome research8(3)1304-14(2009 Mar)
Large-scale proteomics and phosphoproteomics of urinary exosomes.
Gonzales PA, Pisitkun T, Hoffert JD, Tchapyjnikov D, Star RA, Kleta R, Wang NS, Knepper MA
Journal of the American Society of Nephrology : JASN20(2)363-79(2009 Feb)
RIM1alpha phosphorylation at serine-413 by protein kinase A is not required for presynaptic long-term plasticity or learning.
Kaeser PS, Kwon HB, Blundell J, Chevaleyre V, Morishita W, Malenka RC, Powell CM, Castillo PE, S?dhof TC
Proceedings of the National Academy of Sciences of the United States of America105(38)14680-5(2008 Sep)
GeneRIFs: Gene References Into Functions What's a GeneRIF?
14-3-3 proteins directly regulate CaMKKalpha when the enzyme is phosphorylated by protein kinase A on either Ser74 or Ser475.
Title: 14-3-3 Proteins directly regulate Ca(2+)/calmodulin-dependent protein kinase kinase alpha through phosphorylation-dependent multisite binding.
Results suggest that the 14-3-3eta protein regulates hTH1 stability by acting on the N-terminus.
Title: RNAi of 14-3-3eta protein increases intracellular stability of tyrosine hydroxylase.
These data suggest that increases in 14-3-3 proteins mediate THC-induced neuroprotection under conditions of NMDA-induced cellular stress.
Title: Increases in expression of 14-3-3 eta and 14-3-3 zeta transcripts during neuroprotection induced by delta9-tetrahydrocannabinol in AF5 cells.
The following Ywhah gene cDNA ORF clone sequences were retrieved from the NCBI Reference Sequence Database (RefSeq). These sequences represent the protein coding region of the Ywhah cDNA ORF which is encoded by the open reading frame (ORF) sequence. ORF sequences can be delivered in our standard vector, pcDNA3.1+/C-(K)DYK or the vector of your choice as an expression/transfection-ready ORF clone. Not the clone you want? Click here to find your clone.
| CloneID | ORa01791 | |
| Clone ID Related Accession (Same CDS sequence) | NM_013052.1 | |
| Accession Version | NM_013052.1 Latest version! | Documents for ORF clone product in default vector |
| Sequence Information | ORF Nucleotide Sequence (Length: 741bp) Protein sequence SNP |
|
| Vector | pcDNA3.1+/C-(K)DYK or customized vector |  User Manual |
| Clone information | Clone Map | MSDS |
| Tag on pcDNA3.1+/C-(K)DYK | C terminal DYKDDDDK tags | |
| ORF Insert Method | CloneEZ™ Seamless cloning technology | |
| Insert Structure | linear | |
| Update Date | 2019-12-25 | |
| Organism | Rattus norvegicus(Norway rat) | |
| Product | 14-3-3 protein eta | |
| Comment | Comment: PROVISIONAL REFSEQ: This record has not yet been subject to final NCBI review. The reference sequence was derived from D17445.1. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Gene record to access additional publications. ##Evidence-Data-START## Transcript exon combination :: D17445.1, CF110048.1 [ECO:0000332] RNAseq introns :: single sample supports all introns SAMD00052296, SAMD00052297 [ECO:0000348] ##Evidence-Data-END## | |
1 | ATGGGGGACC GAGAGCAGCT GCTGCAGCGG GCGCGACTGG CGGAGCAGGC GGAGCGCTAC |
The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.
| RefSeq | NP_037184.1 |
| CDS | 176..916 |
| Translation |
Target ORF information:
Target ORF information:
|
 NM_013052.1 |
ORF Insert Sequence:
1 | ATGGGGGACC GAGAGCAGCT GCTGCAGCGG GCGCGACTGG CGGAGCAGGC GGAGCGCTAC |
The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.
 |
Quantitative proteomic analysis of human substantia nigra in Alzheimer's disease, Huntington's disease and Multiple sclerosis. |
|
MHC class II-associated proteins in B-cell exosomes and potential functional implications for exosome biogenesis. |
|
Proteomic analysis of human parotid gland exosomes by multidimensional protein identification technology (MudPIT). |
|
Large-scale proteomics and phosphoproteomics of urinary exosomes. |
|
RIM1alpha phosphorylation at serine-413 by protein kinase A is not required for presynaptic long-term plasticity or learning. |