Cd3d cDNA ORF clone, Rattus norvegicus(Norway rat)

Gene
Clones
gRNAs

Gene Symbol	Cd3d
Entrez Gene ID	25710
Full Name	CD3d molecule
General protein information	Preferred Names CD3d molecule Names T-cell surface glycoprotein CD3 delta chain CD3 antigen delta polypeptide CD3 molecule delta polypeptide CD3 molecule, delta T-cell receptor T3 delta chain
Gene Type	protein-coding
Organism	Rattus norvegicus(Norway rat)
Genome	Chromosome: 8 Map Location: 8q22
Summary	putative component of the CD3 T-cell receptor [RGD, Feb 2006].

mRNA and Protein(s)

mRNA Protein Name

NM_013169.1 NP_037301.1 T-cell surface glycoprotein CD3 delta chain precursor
Pathways from BioSystems

mRNA	Protein	Name
NM_013169.1	NP_037301.1	T-cell surface glycoprotein CD3 delta chain precursor

Homologies

Homo sapiens (human)	CD3D	NP_000723.1
	CD3D	XP_001097302.1
Xenopus tropicalis (tropical clawed frog)	cd3g	NP_001135555.1
Bos taurus (cattle)	CD3D	NP_001029205.1
Rattus norvegicus (Norway rat)	Cd3d	NP_037301.1
Mus musculus (house mouse)	Cd3d	NP_038515.3
Gallus gallus (chicken)	CD3D	NP_990843.1
Pan troglodytes (chimpanzee)	CD3D	XP_508789.2
Canis lupus familiaris (dog)	CD3D	XP_536556.1

Gene Ontology
Bibliography

Related articles in PubMed

Biochemical evidence for the presence of a single CD3delta and CD3gamma chain in the surface T cell receptor/CD3 complex.
Pan Q, Gollapudi AS, Dave VP
The Journal of biological chemistry279(49)51068-74(2004 Dec)

High-density rat radiation hybrid maps containing over 24,000 SSLPs, genes, and ESTs provide a direct link to the rat genome sequence.
Kwitek AE, Gullings-Handley J, Yu J, Carlos DC, Orlebeke K, Nie J, Eckert J, Lemke A, Andrae JW, Bromberg S, Pasko D, Chen D, Scheetz TE, Casavant TL, Soares MB, Sheffield VC, Tonellato PJ, Jacob HJ
Genome research14(4)750-7(2004 Apr)

Homooligomerization of the cytoplasmic domain of the T cell receptor zeta chain and of other proteins containing the immunoreceptor tyrosine-based activation motif.
Sigalov A, Aivazian D, Stern L
Biochemistry43(7)2049-61(2004 Feb)

Effect of CD3delta deficiency on maturation of alpha/beta and gamma/delta T-cell lineages in severe combined immunodeficiency.
Dadi HK, Simon AJ, Roifman CM
The New England journal of medicine349(19)1821-8(2003 Nov)

Initiation of TCR signaling: regulation within CD3 dimers.
Alarc?n B, Gil D, Delgado P, Schamel WW
Immunological reviews19138-46(2003 Feb)

GeneRIFs: Gene References Into Functions What's a GeneRIF?

The following Cd3d gene cDNA ORF clone sequences were retrieved from the NCBI Reference Sequence Database (RefSeq). These sequences represent the protein coding region of the Cd3d cDNA ORF which is encoded by the open reading frame (ORF) sequence. ORF sequences can be delivered in our standard vector, pcDNA3.1⁺/C-(K)DYK or the vector of your choice as an expression/transfection-ready ORF clone. Not the clone you want? Click here to find your clone.

***CloneID	Accession No.	Definition	**Vector	*Turnaround time	Price (USD)	Select
ORa02201	NM_013169.1 Latest version!	Rattus norvegicus CD3d molecule (Cd3d), mRNA.	pcDNA3.1-C-(k)DYK or customized vector	7-9	$69.30 $99.00

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** You may select a custom vector to replace pcDNA3.1+/C-(K)DYK after clone is added to cart.

** GenScript guarantees 100% sequence accuracy of all synthetic DNA constructs we deliver, but we do not guarantee protein expression in your experimental system. Protein expression is influenced by many factors that may vary between experiments or laboratories. In addition, please pay attention to the signal peptide, propeptide and transit peptide in target ORF, which may affect the choice of vector (N/C terminal tag vector).

***One clone ID might be correlated to multiple accession numbers, which share the same CDS sequence.

Reference Sequences (Refseq)

Cd3d ( NM_013169.1 ) cDNA ORF clone, Rattus norvegicus(Norway rat) -> NP_037301.1 Rattus norvegicus CD3d molecule (Cd3d), mRNA.

Price & Availability↑

CloneID	ORa02201
Clone ID Related Accession (Same CDS sequence)	NM_013169.1
Accession Version	NM_013169.1 Latest version!	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 522bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2019-11-15
Organism	Rattus norvegicus(Norway rat)
Product	T-cell surface glycoprotein CD3 delta chain precursor
Comment	Comment: PROVISIONAL REFSEQ: This record has not yet been subject to final NCBI review. The reference sequence was derived from X53430.1. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Gene record to access additional publications. ##Evidence-Data-START## Transcript exon combination :: X53430.1, FM074502.1 [ECO:0000332] RNAseq introns :: single sample supports all introns SAMEA2689594, SAMEA2689599 [ECO:0000348] ##Evidence-Data-END##

ATGGAGCACT ATGGAATTCT GGTTAGTCTG CTACTGGCTA CTGTTCTCCC CCAAGGGAGC 
CCCTTCAAGA TAGAAGTGGT TGAATATGAG GACAAAGTGT TTGTGAATTG CAACACCAGC 
ATCAGGCATC TAGATGGATC AGTGGAAAGA TGGTTGACCA AAAATAAATC ACTCATCTTG 
GGCAAAGGCA TCCTGGACCC ACGAGGGATG TATATGTGTA ATGGGACAGA GGAGCTGGCG 
AAGGAGGTGT CGACTGTTCA AGTATATTAC CGAATGTGCC AGAACTGTGT GGAGCTGGAC 
TCAGCCACCC TGGCTGGTGT CATCATCACT GATCTCATCG CCACTCTGCT CCTGGCTTTG 
GGGGTCTACT GCTTTGCAGG CCATGAGACC GGAAGACTTT CTGGGGCTGT TGACACTCAA 
GTCCTGTTGA AGAACGAGCA GCTGTATCAG CCTCTTCGAG ATCGCGATGA TGCCCAGTAC 
AGCCGTCTTG GAGGGAACTG GCCCCGGAAC AAAAGGTCTT GA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	NP_037301.1
CDS	62..583
Translation	MEHYGILVSLLLATVLPQGSPFKIEVVEYEDKVFVNCNTSIRHLDGSVERWLTKNKSLILGKGILDPRGMYMCNGTEELAKEVSTVQVYYRMCQNCVELDSATLAGVIITDLIATLLLALGVYCFAGHETGRLSGAVDTQVLLKNEQLYQPLRDRDDAQYSRLGGNWPRNKRS

Target ORF information:

RefSeq Version	NM_013169.1
Organism	Rattus norvegicus(Norway rat)
Definition	Rattus norvegicus CD3d molecule (Cd3d), mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

NM_013169.1

ORF Insert Sequence:

ATGGAGCACT ATGGAATTCT GGTTAGTCTG CTACTGGCTA CTGTTCTCCC CCAAGGGAGC 
CCCTTCAAGA TAGAAGTGGT TGAATATGAG GACAAAGTGT TTGTGAATTG CAACACCAGC 
ATCAGGCATC TAGATGGATC AGTGGAAAGA TGGTTGACCA AAAATAAATC ACTCATCTTG 
GGCAAAGGCA TCCTGGACCC ACGAGGGATG TATATGTGTA ATGGGACAGA GGAGCTGGCG 
AAGGAGGTGT CGACTGTTCA AGTATATTAC CGAATGTGCC AGAACTGTGT GGAGCTGGAC 
TCAGCCACCC TGGCTGGTGT CATCATCACT GATCTCATCG CCACTCTGCT CCTGGCTTTG 
GGGGTCTACT GCTTTGCAGG CCATGAGACC GGAAGACTTT CTGGGGCTGT TGACACTCAA 
GTCCTGTTGA AGAACGAGCA GCTGTATCAG CCTCTTCGAG ATCGCGATGA TGCCCAGTAC 
AGCCGTCTTG GAGGGAACTG GCCCCGGAAC AAAAGGTCTT GA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

PubMed

Biochemical evidence for the presence of a single CD3delta and CD3gamma chain in the surface T cell receptor/CD3 complex.
The Journal of biological chemistry279(49)51068-74(2004 Dec)
Pan Q,Gollapudi AS,Dave VP

High-density rat radiation hybrid maps containing over 24,000 SSLPs, genes, and ESTs provide a direct link to the rat genome sequence.
Genome research14(4)750-7(2004 Apr)
Kwitek AE,Gullings-Handley J,Yu J,Carlos DC,Orlebeke K,Nie J,Eckert J,Lemke A,Andrae JW,Bromberg S,Pasko D,Chen D,Scheetz TE,Casavant TL,Soares MB,Sheffield VC,Tonellato PJ,Jacob HJ

Homooligomerization of the cytoplasmic domain of the T cell receptor zeta chain and of other proteins containing the immunoreceptor tyrosine-based activation motif.
Biochemistry43(7)2049-61(2004 Feb)
Sigalov A,Aivazian D,Stern L

Effect of CD3delta deficiency on maturation of alpha/beta and gamma/delta T-cell lineages in severe combined immunodeficiency.
The New England journal of medicine349(19)1821-8(2003 Nov)
Dadi HK,Simon AJ,Roifman CM

Initiation of TCR signaling: regulation within CD3 dimers.
Immunological reviews19138-46(2003 Feb)
Alarc?n B,Gil D,Delgado P,Schamel WW

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Cd3d cDNA ORF clone, Rattus norvegicus(Norway rat)

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Related articles in PubMed

Target ORF information:

Target ORF information:

ORF Insert Sequence:

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