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Rims4 cDNA ORF clone, Rattus norvegicus(Norway rat)

Summary

Gene Symbol Rims4
Entrez Gene ID 266976
Full Name regulating synaptic membrane exocytosis 4
Synonyms Rim4gamma
General protein information
Preferred Names

regulating synaptic membrane exocytosis 4

Names

regulating synaptic membrane exocytosis protein 4
RIM 4
RIM4 gamma
rab3-interacting molecule 4
synaptic regulatory protein RIM4gamma
Gene Type protein-coding
Organism Rattus norvegicus(Norway rat)
Genome

3

3q42
Summary member of a family of synaptic proteins involved in neurotransmitter release [RGD, Feb 2006].

Reference Sequences (RefSeq)

mRNA and Protein(s)

mRNA Protein Name
XM_008762471.2 XP_008760693.1 regulating synaptic membrane exocytosis protein 4 isoform X1
NM_170666.1 NP_733766.1 regulating synaptic membrane exocytosis protein 4

Pathways from BioSystems


Homologies


Canis lupus familiaris (dog) RIMS4 XP_003433260.1
Bos taurus (cattle) RIMS4 XP_002692374.2
Rattus norvegicus (Norway rat) Rims4 NP_733766.1
Danio rerio (zebrafish) LOC570923 XP_005166329.1
Pan troglodytes (chimpanzee) RIMS4 XP_001144803.2
Homo sapiens (human) RIMS4 NP_001192246.1
Mus musculus (house mouse) Rims4 NP_898844.1
Xenopus tropicalis (tropical clawed frog) rims4 XP_004918712.1
RIMS4 XP_001109689.1
Gallus gallus (chicken) RIMS4 XP_425700.2

Gene Ontology


Bibliography

Related articles in PubMed

RIM3? and RIM4? are key regulators of neuronal arborization.
Alvarez-Baron E, Michel K, Mittelstaedt T, Opitz T, Schmitz F, Beck H, Dietrich D, Becker AJ, Schoch S
The Journal of neuroscience : the official journal of the Society for Neuroscience33(2)824-39(2013 Jan)

Rab3-interacting molecule gamma isoforms lacking the Rab3-binding domain induce long lasting currents but block neurotransmitter vesicle anchoring in voltage-dependent P/Q-type Ca2+ channels.
Uriu Y, Kiyonaka S, Miki T, Yagi M, Akiyama S, Mori E, Nakao A, Beedle AM, Campbell KP, Wakamori M, Mori Y
The Journal of biological chemistry285(28)21750-67(2010 Jul)

Genomic definition of RIM proteins: evolutionary amplification of a family of synaptic regulatory proteins.
Wang Y, S?dhof TC
Genomics81(2)126-37(2003 Feb)

GeneRIFs: Gene References Into Functions What's a GeneRIF?

The following Rims4 gene cDNA ORF clone sequences were retrieved from the NCBI Reference Sequence Database (RefSeq). These sequences represent the protein coding region of the Rims4 cDNA ORF which is encoded by the open reading frame (ORF) sequence. ORF sequences can be delivered in our standard vector, pcDNA3.1+/C-(K)DYK or the vector of your choice as an expression/transfection-ready ORF clone. Not the clone you want? Click here to find your clone.

***CloneID Accession No. Definition **Vector *Turnaround time Price (USD) Select
ORa03208 NM_170666.1
Latest version!		 Rattus norvegicus regulating synaptic membrane exocytosis 4 (Rims4), mRNA. pcDNA3.1+/C-(K)DYK or customized vector 7-9 $139.30
$199.00
ORa44519 XM_008762471.2
Latest version!		 Rattus norvegicus regulating synaptic membrane exocytosis 4 (Rims4), transcript variant X1, mRNA. pcDNA3.1+/C-(K)DYK or customized vector 7-9 $139.30
$199.00

ORF Online Only Promotion

Next-day Shipping ORF Clones ( in default vector with tag)
1 Clone 30% OFF
2-4 Clone 40% OFF
5 or more Clone 50% OFF
All Other ORF Clones
30% OFF

*Business Day

** You may select a custom vector to replace pcDNA3.1+/C-(K)DYK after clone is added to cart.

** GenScript guarantees 100% sequence accuracy of all synthetic DNA constructs we deliver, but we do not guarantee protein expression in your experimental system. Protein expression is influenced by many factors that may vary between experiments or laboratories. In addition, please pay attention to the signal peptide, propeptide and transit peptide in target ORF, which may affect the choice of vector (N/C terminal tag vector).

***One clone ID might be correlated to multiple accession numbers, which share the same CDS sequence.

Reference Sequences (Refseq)


CloneID ORa03208
Clone ID Related Accession (Same CDS sequence) NM_170666.1
Accession Version NM_170666.1 Latest version! Documents for ORF clone product in default vector
Sequence Information ORF Nucleotide Sequence (Length: 810bp)
Protein sequence
SNP
Vector pcDNA3.1+/C-(K)DYK or customized vector User Manual
Clone information Clone Map MSDS
Tag on pcDNA3.1+/C-(K)DYK C terminal DYKDDDDK tags
ORF Insert Method CloneEZ™ Seamless cloning technology
Insert Structure linear
Update Date 2019-09-20
Organism Rattus norvegicus(Norway rat)
Product regulating synaptic membrane exocytosis protein 4
Comment Comment: PROVISIONAL REFSEQ: This record has not yet been subject to final NCBI review. The reference sequence was derived from AF548739.1. ##Evidence-Data-START## Transcript exon combination :: AF548739.1 [ECO:0000332] RNAseq introns :: single sample supports all introns SAMN00632258 [ECO:0000348] ##Evidence-Data-END## 

1
61
121
181
241
301
361
421
481
541
601
661
721
781
ATGGAGCGCT CGCAGAGCCG CCTCAGCCTG TCCGCCTCCT TCGAGGCGCT CGCCATCTAC 
TTCCCGTGCA TGAACTCCTT CGATGATGAG GACGCAGCAG ACAGCCGGAG GCTGAAGGGT 
GCCATCCAGA GAAGCACAGA GACAGGGCTG GCCGTGGAGA TGCCCAGCCG GACGTTACGC 
CAAGCCAGCC ATGAGTCCAT CGAGGACAGC ATGAATAGCT ATGGCTCAGA GGGCAACCTG 
AACTATGGAG GAGTTTGTCT AGCTTCGGAT GCCCAGTTCA GTGACTTCCT GGGGAGCATG 
GGGCCAGCAC AGTTTGTGGG CCGCCAGACC CTGGCTACCA CACCCATGGG GGGTGTGGAG 
ATCGGTTTAC AGGAGCGGAA CGGTCAGCTG GAGGTGGACA TCATCCAGGC ACGCGGGCTG 
ACTGCCAAGC CAGGCTCGAA GACACTGCCA GCTGCCTATA TCAAGGCCTA TCTGCTGGAA 
AATGGTGTCT GCATTGCCAA GAAGAAGACC AAAGTGGCCC GCAAGTCACT GGACCCATTG 
TACAACCAGG TGCTTCTGTT TCCTGAGAGT CCCCAGGGCA AAGTCCTGCA GGTAATTGTG 
TGGGGAAACT ACGGACGAAT GGAGCGGAAG CAGTTCATGG GCGTGGCTCG AGTGCTGCTG 
GAGGAACTGG ACTTGACCAC CCTGGCCGTG GGTTGGTACA AGCTCTTCCC CACCTCCTCC 
ATGGTGGACC CAGCCACAGG TCCCCTGCTT CGGCAGGCAT CCCAGCTGTC CCTCGAGAGC 
ACCGTGGGGC CCTGTGGCGA GCGATCTTAA

The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.

RefSeq NP_733766.1
CDS1..810
Translation

Target ORF information:

RefSeq Version NM_170666.1
Organism Rattus norvegicus(Norway rat)
Definition Rattus norvegicus regulating synaptic membrane exocytosis 4 (Rims4), mRNA.

Target ORF information:

Epitope DYKDDDDK
Bacterial selection AMPR
Mammalian selection NeoR
Vector pcDNA3.1+/C-(K)DYK
 NM_170666.1

ORF Insert Sequence:

1
61
121
181
241
301
361
421
481
541
601
661
721
781
ATGGAGCGCT CGCAGAGCCG CCTCAGCCTG TCCGCCTCCT TCGAGGCGCT CGCCATCTAC 
TTCCCGTGCA TGAACTCCTT CGATGATGAG GACGCAGCAG ACAGCCGGAG GCTGAAGGGT 
GCCATCCAGA GAAGCACAGA GACAGGGCTG GCCGTGGAGA TGCCCAGCCG GACGTTACGC 
CAAGCCAGCC ATGAGTCCAT CGAGGACAGC ATGAATAGCT ATGGCTCAGA GGGCAACCTG 
AACTATGGAG GAGTTTGTCT AGCTTCGGAT GCCCAGTTCA GTGACTTCCT GGGGAGCATG 
GGGCCAGCAC AGTTTGTGGG CCGCCAGACC CTGGCTACCA CACCCATGGG GGGTGTGGAG 
ATCGGTTTAC AGGAGCGGAA CGGTCAGCTG GAGGTGGACA TCATCCAGGC ACGCGGGCTG 
ACTGCCAAGC CAGGCTCGAA GACACTGCCA GCTGCCTATA TCAAGGCCTA TCTGCTGGAA 
AATGGTGTCT GCATTGCCAA GAAGAAGACC AAAGTGGCCC GCAAGTCACT GGACCCATTG 
TACAACCAGG TGCTTCTGTT TCCTGAGAGT CCCCAGGGCA AAGTCCTGCA GGTAATTGTG 
TGGGGAAACT ACGGACGAAT GGAGCGGAAG CAGTTCATGG GCGTGGCTCG AGTGCTGCTG 
GAGGAACTGG ACTTGACCAC CCTGGCCGTG GGTTGGTACA AGCTCTTCCC CACCTCCTCC 
ATGGTGGACC CAGCCACAGG TCCCCTGCTT CGGCAGGCAT CCCAGCTGTC CCTCGAGAGC 
ACCGTGGGGC CCTGTGGCGA GCGATCTTAA

The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.

CloneID ORa44519
Clone ID Related Accession (Same CDS sequence) XM_008762471.2
Accession Version XM_008762471.2 Latest version! Documents for ORF clone product in default vector
Sequence Information ORF Nucleotide Sequence (Length: 807bp)
Protein sequence
SNP
Vector pcDNA3.1+/C-(K)DYK or customized vector User Manual
Clone information Clone Map MSDS
Tag on pcDNA3.1+/C-(K)DYK C terminal DYKDDDDK tags
ORF Insert Method CloneEZ™ Seamless cloning technology
Insert Structure linear
Update Date 2016-07-25
Organism Rattus norvegicus(Norway rat)
Product regulating synaptic membrane exocytosis protein 4 isoform X1
Comment Comment: MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_005102.4) annotated using gene prediction method: Gnomon, supported by EST evidence. Also see: Documentation of NCBI's Annotation Process On Jul 26, 2016 this sequence version replaced XM_008762471.1. ##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Version :: Rattus norvegicus Annotation Release 106 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 7.1 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END## 

1
61
121
181
241
301
361
421
481
541
601
661
721
781
ATGGAGCGCT CGCAGAGCCG CCTCAGCCTG TCCGCCTCCT TCGAGGCGCT CGCCATCTAC 
TTCCCGTGCA TGAACTCCTT CGATGATGAG GACGCAGACA GCCGGAGGCT GAAGGGTGCC 
ATCCAGAGAA GCACAGAGAC AGGGCTGGCC GTGGAGATGC CCAGCCGGAC GTTACGCCAA 
GCCAGCCATG AGTCCATCGA GGACAGCATG AATAGCTATG GCTCAGAGGG CAACCTGAAC 
TATGGAGGAG TTTGTCTAGC TTCGGATGCC CAGTTCAGTG ACTTCCTGGG GAGCATGGGG 
CCAGCACAGT TTGTGGGCCG CCAGACCCTG GCTACCACAC CCATGGGGGA TGTGGAGATC 
GGTTTACAGG AGCGGAACGG TCAGCTGGAG GTGGACATCA TCCAGGCACG CGGGCTGACT 
GCCAAGCCAG GCTCGAAGAC ACTGCCAGCT GCCTATATCA AGGCCTATCT GCTGGAAAAT 
GGTGTCTGCA TTGCCAAGAA GAAGACCAAA GTGGCCCGCA AGTCACTGGA CCCGTTGTAC 
AACCAGGTGC TTCTGTTTCC TGAGAGTCCC CAGGGCAAAG TCCTGCAGGT AATTGTGTGG 
GGAAACTACG GACGAATGGA GCGGAAGCAG TTCATGGGCG TGGCTCGAGT GCTGCTGGAG 
GAACTGGACT TGACCACCCT GGCCGTGGGT TGGTACAAGC TCTTCCCCAC CTCCTCCATG 
GTGGACCCAG CCACAGGTCC CCTGCTTCGG CAGGCATCCC AGCTGTCCCT CGAGAGCACC 
GTGGGGCCCT GTGGCGAGCG ATCTTAA

The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.

RefSeq XP_008760693.1
CDS215..1021
Translation

Target ORF information:

RefSeq Version XM_008762471.2
Organism Rattus norvegicus(Norway rat)
Definition Rattus norvegicus regulating synaptic membrane exocytosis 4 (Rims4), transcript variant X1, mRNA.

Target ORF information:

Epitope DYKDDDDK
Bacterial selection AMPR
Mammalian selection NeoR
Vector pcDNA3.1+/C-(K)DYK
 XM_008762471.2

ORF Insert Sequence:

1
61
121
181
241
301
361
421
481
541
601
661
721
781
ATGGAGCGCT CGCAGAGCCG CCTCAGCCTG TCCGCCTCCT TCGAGGCGCT CGCCATCTAC 
TTCCCGTGCA TGAACTCCTT CGATGATGAG GACGCAGACA GCCGGAGGCT GAAGGGTGCC 
ATCCAGAGAA GCACAGAGAC AGGGCTGGCC GTGGAGATGC CCAGCCGGAC GTTACGCCAA 
GCCAGCCATG AGTCCATCGA GGACAGCATG AATAGCTATG GCTCAGAGGG CAACCTGAAC 
TATGGAGGAG TTTGTCTAGC TTCGGATGCC CAGTTCAGTG ACTTCCTGGG GAGCATGGGG 
CCAGCACAGT TTGTGGGCCG CCAGACCCTG GCTACCACAC CCATGGGGGA TGTGGAGATC 
GGTTTACAGG AGCGGAACGG TCAGCTGGAG GTGGACATCA TCCAGGCACG CGGGCTGACT 
GCCAAGCCAG GCTCGAAGAC ACTGCCAGCT GCCTATATCA AGGCCTATCT GCTGGAAAAT 
GGTGTCTGCA TTGCCAAGAA GAAGACCAAA GTGGCCCGCA AGTCACTGGA CCCGTTGTAC 
AACCAGGTGC TTCTGTTTCC TGAGAGTCCC CAGGGCAAAG TCCTGCAGGT AATTGTGTGG 
GGAAACTACG GACGAATGGA GCGGAAGCAG TTCATGGGCG TGGCTCGAGT GCTGCTGGAG 
GAACTGGACT TGACCACCCT GGCCGTGGGT TGGTACAAGC TCTTCCCCAC CTCCTCCATG 
GTGGACCCAG CCACAGGTCC CCTGCTTCGG CAGGCATCCC AGCTGTCCCT CGAGAGCACC 
GTGGGGCCCT GTGGCGAGCG ATCTTAA

The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.

PubMed

book

RIM3? and RIM4? are key regulators of neuronal arborization.
The Journal of neuroscience : the official journal of the Society for Neuroscience33(2)824-39(2013 Jan)
Alvarez-Baron E,Michel K,Mittelstaedt T,Opitz T,Schmitz F,Beck H,Dietrich D,Becker AJ,Schoch S


book

Rab3-interacting molecule gamma isoforms lacking the Rab3-binding domain induce long lasting currents but block neurotransmitter vesicle anchoring in voltage-dependent P/Q-type Ca2+ channels.
The Journal of biological chemistry285(28)21750-67(2010 Jul)
Uriu Y,Kiyonaka S,Miki T,Yagi M,Akiyama S,Mori E,Nakao A,Beedle AM,Campbell KP,Wakamori M,Mori Y


book

Genomic definition of RIM proteins: evolutionary amplification of a family of synaptic regulatory proteins.
Genomics81(2)126-37(2003 Feb)
Wang Y,S?dhof TC