Gene Symbol | Polq |
Entrez Gene ID | 288079 |
Full Name | DNA polymerase theta |
General protein information |
|
Gene Type | protein-coding |
Organism | Rattus norvegicus(Norway rat) |
Genome |
ORF » Species Summary » Rattus norvegicus » Polq cDNA ORF clone
Gene Symbol | Polq |
Entrez Gene ID | 288079 |
Full Name | DNA polymerase theta |
General protein information |
|
Gene Type | protein-coding |
Organism | Rattus norvegicus(Norway rat) |
Genome |
mRNA | Protein | Name |
---|---|---|
XM_008768716.2 | XP_008766938.1 | DNA polymerase theta isoform X2 |
XM_006248391.2 | XP_006248453.1 | DNA polymerase theta isoform X1 |
XM_006248390.3 | XP_006248452.1 | DNA polymerase theta isoform X1 |
NM_001105878.1 | NP_001099348.1 | DNA polymerase theta |
Canis lupus familiaris (dog) | POLQ | XP_545125.3 |
Gallus gallus (chicken) | POLQ | XP_416549.3 |
Xenopus tropicalis (tropical clawed frog) | polq | NP_001184156.1 |
Bos taurus (cattle) | POLQ | XP_002684835.1 |
Rattus norvegicus (Norway rat) | Polq | NP_001099348.1 |
Danio rerio (zebrafish) | si:rp71-1p14.5 | XP_694437.6 |
Neurospora crassa | NCU07411 | XP_958186.2 |
Anopheles gambiae (African malaria mosquito) | AgaP_AGAP007533 | XP_564726.3 |
Homo sapiens (human) | POLQ | NP_955452.3 |
POLQ | XP_001111254.2 | |
Drosophila melanogaster (fruit fly) | mus308 | NP_524333.1 |
Magnaporthe oryzae (rice blast fungus) | MGG_15295 | XP_003711003.1 |
Pan troglodytes (chimpanzee) | POLQ | XP_001165150.2 |
Mus musculus (house mouse) | Polq | NP_084253.1 |
Structure of the Helicase Domain of DNA Polymerase Theta Reveals a Possible Role in the Microhomology-Mediated End-Joining Pathway.
Newman JA, Cooper CD, Aitkenhead H, Gileadi O
Structure (London, England : 1993)23(12)2319-30(2015 Dec)
Mechanism of microhomology-mediated end-joining promoted by human DNA polymerase ?.
Kent T, Chandramouly G, McDevitt SM, Ozdemir AY, Pomerantz RT
Nature structural & molecular biology22(3)230-7(2015 Mar)
Homologous-recombination-deficient tumours are dependent on Pol?-mediated repair.
Ceccaldi R, Liu JC, Amunugama R, Hajdu I, Primack B, Petalcorin MI, O'Connor KW, Konstantinopoulos PA, Elledge SJ, Boulton SJ, Yusufzai T, D'Andrea AD
Nature518(7538)258-62(2015 Feb)
Mammalian polymerase ? promotes alternative NHEJ and suppresses recombination.
Mateos-Gomez PA, Gong F, Nair N, Miller KM, Lazzerini-Denchi E, Sfeir A
Nature518(7538)254-7(2015 Feb)
Promiscuous DNA synthesis by human DNA polymerase ?.
Hogg M, Sauer-Eriksson AE, Johansson E
Nucleic acids research40(6)2611-22(2012 Mar)
GeneRIFs: Gene References Into Functions What's a GeneRIF?
The following Polq gene cDNA ORF clone sequences were retrieved from the NCBI Reference Sequence Database (RefSeq). These sequences represent the protein coding region of the Polq cDNA ORF which is encoded by the open reading frame (ORF) sequence. ORF sequences can be delivered in our standard vector, pcDNA3.1+/C-(K)DYK or the vector of your choice as an expression/transfection-ready ORF clone. Not the clone you want? Click here to find your clone.
CloneID | ORa11594 | |
Clone ID Related Accession (Same CDS sequence) | NM_001105878.1 | |
Accession Version | NM_001105878.1 Latest version! | Documents for ORF clone product in default vector |
Sequence Information | ORF Nucleotide Sequence (Length: 7644bp) Protein sequence SNP |
|
Vector | pcDNA3.1-C-(k)DYK or customized vector | User Manual |
Clone information | Clone Map | MSDS |
Tag on pcDNA3.1+/C-(K)DYK | C terminal DYKDDDDK tags | |
ORF Insert Method | CloneEZ™ Seamless cloning technology | |
Insert Structure | linear | |
Update Date | 2018-05-27 | |
Organism | Rattus norvegicus(Norway rat) | |
Product | DNA polymerase theta | |
Comment | Comment: PROVISIONAL REFSEQ: This record has not yet been subject to final NCBI review. The reference sequence was derived from CH473967.1. On or before Oct 3, 2007 this sequence version replaced XM_221423.4, XM_001062099.1, XM_001062278.1, XM_001062339.1, XM_001062161.1, XM_001062220.1. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Gene record to access additional publications. ##Evidence-Data-START## RNAseq introns :: mixed/partial sample support SAMD00052296, SAMD00052297 [ECO:0000350] ##Evidence-Data-END## |
1 | ATGAGTCTTC CGCGCCGGAG TGGGAAACGG CGGCGTTCAT CATCCGGCTC CGACTCATTC |
The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.
RefSeq | NP_001099348.1 |
CDS | 114..7757 |
Translation |
Target ORF information:
Target ORF information:
|
NM_001105878.1 |
1 | ATGAGTCTTC CGCGCCGGAG TGGGAAACGG CGGCGTTCAT CATCCGGCTC CGACTCATTC |
The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.
CloneID | ORa34306 | |
Clone ID Related Accession (Same CDS sequence) | XM_006248391.2 , XM_006248390.3 | |
Accession Version | XM_006248391.2 Latest version! | Documents for ORF clone product in default vector |
Sequence Information | ORF Nucleotide Sequence (Length: 7128bp) Protein sequence SNP |
|
Vector | pcDNA3.1-C-(k)DYK or customized vector | User Manual |
Clone information | Clone Map | MSDS |
Tag on pcDNA3.1+/C-(K)DYK | C terminal DYKDDDDK tags | |
ORF Insert Method | CloneEZ™ Seamless cloning technology | |
Insert Structure | linear | |
Update Date | 2016-07-25 | |
Organism | Rattus norvegicus(Norway rat) | |
Product | DNA polymerase theta isoform X1 | |
Comment | Comment: MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_005110.4) annotated using gene prediction method: Gnomon, supported by EST evidence. Also see: Documentation of NCBI's Annotation Process On Aug 7, 2014 this sequence version replaced XM_006248391.1. ##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Version :: Rattus norvegicus Annotation Release 106 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 7.1 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END## |
1 | ATGGGCAGCA CCTCACCAAC TGGACGTTTC TCCTCCTTGG ACGTTGCTGT TTGCACTATT |
The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.
RefSeq | XP_006248453.1 |
CDS | 1039..8166 |
Translation |
Target ORF information:
Target ORF information:
|
XM_006248391.2 |
1 | ATGGGCAGCA CCTCACCAAC TGGACGTTTC TCCTCCTTGG ACGTTGCTGT TTGCACTATT |
The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.
CloneID | ORa34306 | |
Clone ID Related Accession (Same CDS sequence) | XM_006248391.2 , XM_006248390.3 | |
Accession Version | XM_006248390.3 Latest version! | Documents for ORF clone product in default vector |
Sequence Information | ORF Nucleotide Sequence (Length: 7128bp) Protein sequence SNP |
|
Vector | pcDNA3.1-C-(k)DYK or customized vector | User Manual |
Clone information | Clone Map | MSDS |
Tag on pcDNA3.1+/C-(K)DYK | C terminal DYKDDDDK tags | |
ORF Insert Method | CloneEZ™ Seamless cloning technology | |
Insert Structure | linear | |
Update Date | 2016-07-25 | |
Organism | Rattus norvegicus(Norway rat) | |
Product | DNA polymerase theta isoform X1 | |
Comment | Comment: MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_005110.4) annotated using gene prediction method: Gnomon, supported by EST evidence. Also see: Documentation of NCBI's Annotation Process On Jul 26, 2016 this sequence version replaced XM_006248390.2. ##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Version :: Rattus norvegicus Annotation Release 106 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 7.1 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END## |
1 | ATGGGCAGCA CCTCACCAAC TGGACGTTTC TCCTCCTTGG ACGTTGCTGT TTGCACTATT |
The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.
RefSeq | XP_006248452.1 |
CDS | 648..7775 |
Translation |
Target ORF information:
Target ORF information:
|
XM_006248390.3 |
1 | ATGGGCAGCA CCTCACCAAC TGGACGTTTC TCCTCCTTGG ACGTTGCTGT TTGCACTATT |
The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.
CloneID | ORa44663 | |
Clone ID Related Accession (Same CDS sequence) | XM_008768716.2 | |
Accession Version | XM_008768716.2 Latest version! | Documents for ORF clone product in default vector |
Sequence Information | ORF Nucleotide Sequence (Length: 6453bp) Protein sequence SNP |
|
Vector | pcDNA3.1-C-(k)DYK or customized vector | User Manual |
Clone information | Clone Map | MSDS |
Tag on pcDNA3.1+/C-(K)DYK | C terminal DYKDDDDK tags | |
ORF Insert Method | CloneEZ™ Seamless cloning technology | |
Insert Structure | linear | |
Update Date | 2016-07-25 | |
Organism | Rattus norvegicus(Norway rat) | |
Product | DNA polymerase theta isoform X2 | |
Comment | Comment: MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_005110.4) annotated using gene prediction method: Gnomon, supported by EST evidence. Also see: Documentation of NCBI's Annotation Process On Jul 26, 2016 this sequence version replaced XM_008768716.1. ##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Version :: Rattus norvegicus Annotation Release 106 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 7.1 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END## |
1 | ATGAGTCTTC CGCGCCGGAG TGGGAAACGG CGGCGTTCAT CATCCGGCTC CGACTCATTC |
The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.
RefSeq | XP_008766938.1 |
CDS | 130..6582 |
Translation |
Target ORF information:
Target ORF information:
|
XM_008768716.2 |
1 | ATGAGTCTTC CGCGCCGGAG TGGGAAACGG CGGCGTTCAT CATCCGGCTC CGACTCATTC |
The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.
Structure of the Helicase Domain of DNA Polymerase Theta Reveals a Possible Role in the Microhomology-Mediated End-Joining Pathway. |
Mechanism of microhomology-mediated end-joining promoted by human DNA polymerase ?. |
Homologous-recombination-deficient tumours are dependent on Pol?-mediated repair. |
Mammalian polymerase ? promotes alternative NHEJ and suppresses recombination. |
Promiscuous DNA synthesis by human DNA polymerase ?. |