Gene Symbol | Trim50 |
Entrez Gene ID | 288596 |
Full Name | tripartite motif-containing 50 |
General protein information |
|
Gene Type | protein-coding |
Organism | Rattus norvegicus(Norway rat) |
Genome |
ORF » Species Summary » Rattus norvegicus » Trim50 cDNA ORF clone
gRNAs
Gene Symbol | Trim50 |
Entrez Gene ID | 288596 |
Full Name | tripartite motif-containing 50 |
General protein information |
|
Gene Type | protein-coding |
Organism | Rattus norvegicus(Norway rat) |
Genome |
mRNA | Protein | Name |
---|---|---|
XM_006249128.3 | XP_006249190.1 | E3 ubiquitin-protein ligase TRIM50 isoform X1 |
XM_017598298.1 | XP_017453787.1 | E3 ubiquitin-protein ligase TRIM50 isoform X4 |
NM_181080.1 | NP_851594.1 | E3 ubiquitin-protein ligase TRIM50 |
XM_006249130.3 | XP_006249192.1 | E3 ubiquitin-protein ligase TRIM50 isoform X3 |
XM_006249129.3 | XP_006249191.1 | E3 ubiquitin-protein ligase TRIM50 isoform X2 |
Bos taurus (cattle) | TRIM50 | NP_001193185.1 |
Canis lupus familiaris (dog) | TRIM50 | XP_546929.2 |
Rattus norvegicus (Norway rat) | Trim50 | NP_851594.1 |
Gallus gallus (chicken) | TRIM50 | XP_415709.3 |
Homo sapiens (human) | TRIM50 | NP_001268379.1 |
Mus musculus (house mouse) | Trim50 | NP_839971.1 |
Pan troglodytes (chimpanzee) | TRIM50 | XP_527777.2 |
TRIM50 | XP_001110857.1 | |
Xenopus tropicalis (tropical clawed frog) | trim50 | XP_004914939.1 |
TRIM50 protein regulates vesicular trafficking for acid secretion in gastric parietal cells.
Nishi M, Aoyama F, Kisa F, Zhu H, Sun M, Lin P, Ohta H, Van B, Yamamoto S, Kakizawa S, Sakai H, Ma J, Sawaguchi A, Takeshima H
The Journal of biological chemistry287(40)33523-32(2012 Sep)
The E3-ubiquitin ligase TRIM50 interacts with HDAC6 and p62, and promotes the sequestration and clearance of ubiquitinated proteins into the aggresome.
Fusco C, Micale L, Egorov M, Monti M, D'Addetta EV, Augello B, Cozzolino F, Calcagn? A, Fontana A, Polishchuk RS, Didelot G, Reymond A, Pucci P, Merla G
PloS one7(7)e40440(2012)
TRIM27 negatively regulates NOD2 by ubiquitination and proteasomal degradation.
Zurek B, Schoultz I, Neerincx A, Napolitano LM, Birkner K, Bennek E, Sellge G, Lerm M, Meroni G, S?derholm JD, Kufer TA
PloS one7(7)e41255(2012)
GeneRIFs: Gene References Into Functions What's a GeneRIF?
TRIM50 protein regulates vesicular trafficking for acid secretion in gastric parietal cells
Title: TRIM50 protein regulates vesicular trafficking for acid secretion in gastric parietal cells.
The following Trim50 gene cDNA ORF clone sequences were retrieved from the NCBI Reference Sequence Database (RefSeq). These sequences represent the protein coding region of the Trim50 cDNA ORF which is encoded by the open reading frame (ORF) sequence. ORF sequences can be delivered in our standard vector, pcDNA3.1+/C-(K)DYK or the vector of your choice as an expression/transfection-ready ORF clone. Not the clone you want? Click here to find your clone.
CloneID | ORa34751 | |
Clone ID Related Accession (Same CDS sequence) | XM_006249128.3 | |
Accession Version | XM_006249128.3 Latest version! | Documents for ORF clone product in default vector |
Sequence Information | ORF Nucleotide Sequence (Length: 1455bp) Protein sequence SNP |
|
Vector | pcDNA3.1-C-(k)DYK or customized vector | ![]() |
Clone information | Clone Map | ![]() |
Tag on pcDNA3.1+/C-(K)DYK | C terminal DYKDDDDK tags | |
ORF Insert Method | CloneEZ™ Seamless cloning technology | |
Insert Structure | linear | |
Update Date | 2016-07-25 | |
Organism | Rattus norvegicus(Norway rat) | |
Product | E3 ubiquitin-protein ligase TRIM50 isoform X1 | |
Comment | Comment: MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_005111.4) annotated using gene prediction method: Gnomon, supported by mRNA and EST evidence. Also see: Documentation of NCBI's Annotation Process On Jul 26, 2016 this sequence version replaced XM_006249128.2. ##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Version :: Rattus norvegicus Annotation Release 106 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 7.1 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END## |
1 | ATGGCTTGGC AGCTGACTGT GCCGGAACTC CAGGACCAGC TGCAGTGTCC CATTTGCCTG |
The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.
RefSeq | XP_006249190.1 |
CDS | 316..1770 |
Translation |
Target ORF information:
Target ORF information:
|
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1 | ATGGCTTGGC AGCTGACTGT GCCGGAACTC CAGGACCAGC TGCAGTGTCC CATTTGCCTG |
The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.
CloneID | ORa04143 | |
Clone ID Related Accession (Same CDS sequence) | NM_181080.1 , XM_006249129.3 | |
Accession Version | NM_181080.1 Latest version! | Documents for ORF clone product in default vector |
Sequence Information | ORF Nucleotide Sequence (Length: 1452bp) Protein sequence SNP |
|
Vector | pcDNA3.1-C-(k)DYK or customized vector | ![]() |
Clone information | Clone Map | ![]() |
Tag on pcDNA3.1+/C-(K)DYK | C terminal DYKDDDDK tags | |
ORF Insert Method | CloneEZ™ Seamless cloning technology | |
Insert Structure | linear | |
Update Date | 2019-02-15 | |
Organism | Rattus norvegicus(Norway rat) | |
Product | E3 ubiquitin-protein ligase TRIM50 | |
Comment | Comment: PROVISIONAL REFSEQ: This record has not yet been subject to final NCBI review. The reference sequence was derived from AY081950.1. ##Evidence-Data-START## Transcript exon combination :: AY081950.1 [ECO:0000332] RNAseq introns :: single sample supports all introns SAMEA2689596, SAMN02642652 [ECO:0000348] ##Evidence-Data-END## |
1 | ATGGCTTGGC AGCTGACTGT GCCGGAACTC CAGGACCAGC TGCAGTGTCC CATTTGCCTG |
The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.
RefSeq | NP_851594.1 |
CDS | 1..1452 |
Translation |
Target ORF information:
Target ORF information:
|
![]() |
1 | ATGGCTTGGC AGCTGACTGT GCCGGAACTC CAGGACCAGC TGCAGTGTCC CATTTGCCTG |
The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.
CloneID | ORa04143 | |
Clone ID Related Accession (Same CDS sequence) | NM_181080.1 , XM_006249129.3 | |
Accession Version | XM_006249129.3 Latest version! | Documents for ORF clone product in default vector |
Sequence Information | ORF Nucleotide Sequence (Length: 1452bp) Protein sequence SNP |
|
Vector | pcDNA3.1-C-(k)DYK or customized vector | ![]() |
Clone information | Clone Map | ![]() |
Tag on pcDNA3.1+/C-(K)DYK | C terminal DYKDDDDK tags | |
ORF Insert Method | CloneEZ™ Seamless cloning technology | |
Insert Structure | linear | |
Update Date | 2016-07-25 | |
Organism | Rattus norvegicus(Norway rat) | |
Product | E3 ubiquitin-protein ligase TRIM50 isoform X2 | |
Comment | Comment: MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_005111.4) annotated using gene prediction method: Gnomon, supported by mRNA and EST evidence. Also see: Documentation of NCBI's Annotation Process On Jul 26, 2016 this sequence version replaced XM_006249129.2. ##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Version :: Rattus norvegicus Annotation Release 106 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 7.1 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END## |
1 | ATGGCTTGGC AGCTGACTGT GCCGGAACTC CAGGACCAGC TGCAGTGTCC CATTTGCCTG |
The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.
RefSeq | XP_006249191.1 |
CDS | 318..1769 |
Translation |
Target ORF information:
Target ORF information:
|
![]() |
1 | ATGGCTTGGC AGCTGACTGT GCCGGAACTC CAGGACCAGC TGCAGTGTCC CATTTGCCTG |
The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.
CloneID | ORa34752 | |
Clone ID Related Accession (Same CDS sequence) | XM_006249130.3 | |
Accession Version | XM_006249130.3 Latest version! | Documents for ORF clone product in default vector |
Sequence Information | ORF Nucleotide Sequence (Length: 1359bp) Protein sequence SNP |
|
Vector | pcDNA3.1-C-(k)DYK or customized vector | ![]() |
Clone information | Clone Map | ![]() |
Tag on pcDNA3.1+/C-(K)DYK | C terminal DYKDDDDK tags | |
ORF Insert Method | CloneEZ™ Seamless cloning technology | |
Insert Structure | linear | |
Update Date | 2016-07-25 | |
Organism | Rattus norvegicus(Norway rat) | |
Product | E3 ubiquitin-protein ligase TRIM50 isoform X3 | |
Comment | Comment: MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_005111.4) annotated using gene prediction method: Gnomon, supported by EST evidence. Also see: Documentation of NCBI's Annotation Process On Jul 26, 2016 this sequence version replaced XM_006249130.2. ##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Version :: Rattus norvegicus Annotation Release 106 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 7.1 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END## |
1 | ATGGCTTGGC AGCTGACTGT GCCGGAACTC CAGGACCAGC TGCAGTGTCC CATTTGCCTG |
The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.
RefSeq | XP_006249192.1 |
CDS | 319..1677 |
Translation |
Target ORF information:
Target ORF information:
|
![]() |
1 | ATGGCTTGGC AGCTGACTGT GCCGGAACTC CAGGACCAGC TGCAGTGTCC CATTTGCCTG |
The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.
CloneID | ORa57795 | |
Clone ID Related Accession (Same CDS sequence) | XM_017598298.1 | |
Accession Version | XM_017598298.1 Latest version! | Documents for ORF clone product in default vector |
Sequence Information | ORF Nucleotide Sequence (Length: 750bp) Protein sequence SNP |
|
Vector | pcDNA3.1-C-(k)DYK or customized vector | ![]() |
Clone information | Clone Map | ![]() |
Tag on pcDNA3.1+/C-(K)DYK | C terminal DYKDDDDK tags | |
ORF Insert Method | CloneEZ™ Seamless cloning technology | |
Insert Structure | linear | |
Update Date | 2016-07-25 | |
Organism | Rattus norvegicus(Norway rat) | |
Product | E3 ubiquitin-protein ligase TRIM50 isoform X4 | |
Comment | Comment: MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_005111.4) annotated using gene prediction method: Gnomon. Also see: Documentation of NCBI's Annotation Process ##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Version :: Rattus norvegicus Annotation Release 106 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 7.1 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END## |
1 | ATGGCTTGGC AGCTGACTGT GCCGGAACTC CAGGACCAGC TGCAGTGTCC CATTTGCCTG |
The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.
RefSeq | XP_017453787.1 |
CDS | 320..1069 |
Translation |
Target ORF information:
Target ORF information:
|
![]() |
1 | ATGGCTTGGC AGCTGACTGT GCCGGAACTC CAGGACCAGC TGCAGTGTCC CATTTGCCTG |
The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.
TRIM50 protein regulates vesicular trafficking for acid secretion in gastric parietal cells. |
The E3-ubiquitin ligase TRIM50 interacts with HDAC6 and p62, and promotes the sequestration and clearance of ubiquitinated proteins into the aggresome. |
TRIM27 negatively regulates NOD2 by ubiquitination and proteasomal degradation. |